scholarly journals Genetic Variations in the Bovine Fatty Acid Desaturase 6 (FADS6) Are Associated with Fatty Acid Composition in Hanwoo Cattle

2016 ◽  
Vol 8 (12) ◽  
pp. 41 ◽  
Author(s):  
Krishnamoorthy Srikanth ◽  
Eunjin Lee ◽  
Anam Kwan ◽  
Youngjo Lim ◽  
Hoyoung Chung
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Genetic Variants ◽  
Fatty Acid Desaturase ◽  
Domain Family ◽  
Sequence Analyses ◽  
Hardy Weinberg Equilibrium ◽  
Hanwoo Cattle ◽  
Intron 2

The purpose of this study was to discover genetic variants in the bovine fatty acid desaturase domain family member 6 (FADS6) gene and to test for associations with fatty acid composition (FAC) as well as carcass traits such as backfat thickness (BFT) and marbling scores (MAR). 90 Hanwoo steers were used in the study, and sequence analyses detected 4 genetic variants in intron 2 (approximately 10,890 bp) of FADS6. The FADS6 SNPs showed no significant departures from HWE (Hardy-Weinberg Equilibrium) except g.57772511C > T that did not have heterozygous genotypes. Genotypes of g.57770744A > G and g.57772511C > T were significantly associated with Vaccenic (C18:ln7), Palmitoleic (C16:ln7), and Stearic (C18:0) acids. The analysis confirmed dominance and additive effects for the g.57770744A > G and g.57772511C > T segments, respectively. A positive correlation (31.1%, P = 0.003) between BFT and Linolenic acid (C18:3n3) and a negative (-36.5%, P < 0.001) correlation between MAR and Eicosenoic acids (C20:1n9) were observed.

scholarly journals GWAS identifies genetic variants associated with omega-3 fatty acid composition of Atlantic salmon fillets

Aquaculture ◽  
2020 ◽  
Vol 514 ◽  
pp. 734494 ◽  
Author(s):  
Siri S. Horn ◽  
Bente Ruyter ◽  
Theo H.E. Meuwissen ◽  
Hooman Moghadam ◽  
Borghild Hillestad ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Atlantic Salmon ◽  
Acid Composition ◽  
Genetic Variants ◽  
Omega 3 ◽  
Omega 3 Fatty Acid

Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition

Meat Science ◽  
2015 ◽  
Vol 110 ◽  
pp. 46-51 ◽  
Author(s):  
Joonki Hong ◽  
Duwan Kim ◽  
Kyuho Cho ◽  
Soojin Sa ◽  
Sunho Choi ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Genetic Variants

scholarly journals Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition

2012 ◽  
Vol 97 (1) ◽  
pp. 195-207 ◽  
Author(s):  
Leah G Gillingham ◽  
Scott V Harding ◽  
Todd C Rideout ◽  
Natalia Yurkova ◽  
Stephen C Cunnane ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linolenic Acid ◽  
Acid Composition ◽  
Genetic Variants ◽  
Acid Metabolism ◽  
Plasma Fatty Acid ◽  
Dietary Oils ◽  
Plasma Fatty Acid Composition

scholarly journals Genome-Wide Association Study for Fatty Acid Composition in American Angus Cattle

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2424
Author(s):  
Muhammad Dawood ◽  
Luke Matthew Kramer ◽  
Muhammad Imran Shabbir ◽  
James Mark Reecy
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Thyroid Hormone ◽  
Acid Composition ◽  
Acid Content ◽  
Fatty Acid Synthase ◽  
Fatty Acid Content ◽  
Fatty Acid Desaturase ◽  
Fatty Acid Binding ◽  
Genomic Regions

Livestock is an important commodity playing a major role in the global economy. Red meat plays an important role in human life, as it is a good source of animal protein and energy. The fatty acid content of beef has been shown to impact the eating experience and nutritional value of beef. Therefore, this study aimed to identify genomic regions which can account for genetic variation in meat fatty acid content. Genotypes imputed to the Illumina BovineHD 770K BeadChip were used in this study. Thirty-six 1-Mb genomic regions with a posterior probability of inclusion (PPI) greater than 0.90 were identified to be associated with variation in the content of at least one fatty acid. The genomic regions (1Mb) which were associated with more than one fatty acid trait with high genetic variance and harbored good candidate genes were on Chromosome (Chr) 6 (fatty acid binding protein 2), Chr 19 (thyroid hormone receptor alpha, fatty acid synthase), Chr 26 (stearoyl-CoA desaturase), and Chr 29 (thyroid hormone responsive, fatty acid desaturase 2, and fatty acid desaturase 3). Further studies are required to identify the causal variants within the identified genomic regions. Findings from the present study will help to increase understanding of the variation in fatty acid content of beef and help to enhance selection for beef with improved fatty acid composition.

Sign in / Sign up

Export Citation Format

Share Document