scholarly journals Role of Nutraceuticals in Cancer Therapy

2014 ◽  
Vol 3 (4) ◽  
pp. 18 ◽  
Author(s):  
Elia Ranzato ◽  
Simona Martinotti ◽  
Cinzia Myriam Calabrese ◽  
Giorgio Calabrese
Keyword(s):  
Current Knowledge ◽  
Well Being ◽  
Therapeutic Agents ◽  
Antagonistic Activity ◽  
Molecular Processes ◽  
Cancer Treatments ◽  
Therapeutic Properties ◽  
Health And Well Being ◽  
Food Value

<p>Nutraceuticals are natural bioactive products with food value and promising therapeutic properties in several diseases. Current cancer treatments, such as chemotherapy, radiotherapy and surgery, induce unintended side effects compromising also health and well-being of patients. Emerging studies suggest that some plant-based agents may impact cellular and molecular processes underlying tumor progression. However, some of these molecules might also play an antagonistic activity against classic therapeutic agents. The aim of this article is to review the current knowledge underpinning the use of nutraceuticals in cancer prevention and therapy.</p>

scholarly journals Impact of nutrition on ageing the process. Bridging the Gap: the animal perspective

2015 ◽  
Vol 113 (S1) ◽  
pp. S23-S25 ◽  
Author(s):  
Richard F. Butterwick
Keyword(s):  
Current Knowledge ◽  
Later Life ◽  
Well Being ◽  
Companion Paper ◽  
Ageing Process ◽  
Fundamental Biology ◽  
Health And Well Being

In pets, as in humans, there is increasing interest in interventions that promote ‘health and well-being’ into later life and extend these beyond their current limits. The purpose of this review was to assess the relevance of current knowledge of ageing in humans, described in a companion paper, as well as reviewing recent research on ageing in pet populations. The role of diet and other factors that influence the ageing process and ultimately lifespan in pets are highlighted in this review; in addition, future opportunities and challenges to further our understanding of the ageing process in pets are identified. Advancing knowledge of the fundamental biology of ageing will be key for the development and evaluation of strategies that extend both the quality and the quantity of lifespan in human and pet populations.

Prospective Memory Development Across the Lifespan

2020 ◽  
Vol 25 (3) ◽  
pp. 162-173 ◽  
Author(s):  
Sascha Zuber ◽  
Matthias Kliegel
Keyword(s):  
Prospective Memory ◽  
Healthy Aging ◽  
Present Model ◽  
Current Knowledge ◽  
Well Being ◽  
The Elderly ◽  
Cognitive Factors ◽  
Everyday Functioning ◽  
Integrative Framework

Abstract. Prospective Memory (PM; i.e., the ability to remember to perform planned tasks) represents a key proxy of healthy aging, as it relates to older adults’ everyday functioning, autonomy, and personal well-being. The current review illustrates how PM performance develops across the lifespan and how multiple cognitive and non-cognitive factors influence this trajectory. Further, a new, integrative framework is presented, detailing how those processes interplay in retrieving and executing delayed intentions. Specifically, while most previous models have focused on memory processes, the present model focuses on the role of executive functioning in PM and its development across the lifespan. Finally, a practical outlook is presented, suggesting how the current knowledge can be applied in geriatrics and geropsychology to promote healthy aging by maintaining prospective abilities in the elderly.

Gender Equity and the SDGs

2018 ◽  
Author(s):  
Elizabeth Dettori ◽  
Geeta Rao Gupta
Keyword(s):  
Gender Equity ◽  
Adolescent Girls ◽  
Well Being ◽  
Economic Resources ◽  
The Sustainable Development ◽  
Global Partnership ◽  
Development Goals ◽  
Gender Based ◽  
Health And Well Being

This chapter identifies some of the most stubborn gender-based risks and vulnerabilities girls face as a cohort from preadolescence through late adolescence across the domains of personal capabilities, security, safety, economic resources, and opportunities. It reviews progress made during the Millennium Development Goal era in improving girls’ health and well-being and looks to the role of adolescent girls in advancing the Sustainable Development Goals. The chapter concludes by recommending an approach for global partnership that is linked to national and local actions and that is centered on priority interventions that can catalyze change, at scale, for adolescent girls.

Pateicības izpausmes folklorā psiholoģiskā kontekstā

2021 ◽  
pp. 42-53
Author(s):  
Ieva Ančevska
Keyword(s):  
Family Relationships ◽  
Positive Emotions ◽  
Emotional Health ◽  
Human Life ◽  
Well Being ◽  
Psychological Research ◽  
Neuroscience Research ◽  
Health And Well Being

The article examines the depiction of gratitude and related events in Latvian folklore through comparative evaluation. Gratitude is considered in a psychological context, comparing the attitude expressed in folklore with the findings of modern scientific research. Gratitude is a concept that is usually associated with a relationship or a benefit, it is most often aimed outwards, dedicated to someone else, but at the same time, it creates a pleasant feeling within the person. In modern psychology, gratitude is receiving more and more attention from researchers because its manifestations stimulate the formation of positive emotions and contribute to the improvement of the person’s overall well-being. Research and clinical studies in psychotherapy confirm that gratitude plays an important role in improving mental health and reducing depressive, destructive feelings. In turn, neuroscience research shows the potential of a grateful and positive attitude in strengthening psycho-emotional health and well-being in general. In Latvian folklore, gratitude is depicted as an important part of ritual events, which helps to ensure a positive, balanced connection with the forces of nature, gods, and society. In folklore, the importance of gratitude is emphasised more when building family relationships or accepting various situations and occurrences in life. In both psychological research and the practice of systemic therapy, as well as in folklore, gratitude appears as one of the most important values of interpersonal connection, which promotes the formation of harmonious relationships. Similar to the opinions of psychology, the folk world views emphasise the motivational role of gratitude in improving the quality of human life and health in general.

scholarly journals Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2983 ◽  
Author(s):  
Prabhakaran Soundararajan ◽  
Jung Kim
Keyword(s):  
Antagonistic Activity ◽  
Antagonistic Effect ◽  
Side Chain ◽  
Cruciferous Vegetables ◽  
Related Factor ◽  
Nuclear Factor ◽  
Naturally Occurring ◽  
Therapeutic Properties ◽  
Responsive Element

Glucosinolates (GSL) are naturally occurring β-d-thioglucosides found across the cruciferous vegetables. Core structure formation and side-chain modifications lead to the synthesis of more than 200 types of GSLs in Brassicaceae. Isothiocyanates (ITCs) are chemoprotectives produced as the hydrolyzed product of GSLs by enzyme myrosinase. Benzyl isothiocyanate (BITC), phenethyl isothiocyanate (PEITC) and sulforaphane ([1-isothioyanato-4-(methyl-sulfinyl) butane], SFN) are potential ITCs with efficient therapeutic properties. Beneficial role of BITC, PEITC and SFN was widely studied against various cancers such as breast, brain, blood, bone, colon, gastric, liver, lung, oral, pancreatic, prostate and so forth. Nuclear factor-erythroid 2-related factor-2 (Nrf2) is a key transcription factor limits the tumor progression. Induction of ARE (antioxidant responsive element) and ROS (reactive oxygen species) mediated pathway by Nrf2 controls the activity of nuclear factor-kappaB (NF-κB). NF-κB has a double edged role in the immune system. NF-κB induced during inflammatory is essential for an acute immune process. Meanwhile, hyper activation of NF-κB transcription factors was witnessed in the tumor cells. Antagonistic activity of BITC, PEITC and SFN against cancer was related with the direct/indirect interaction with Nrf2 and NF-κB protein. All three ITCs able to disrupts Nrf2-Keap1 complex and translocate Nrf2 into the nucleus. BITC have the affinity to inhibit the NF-κB than SFN due to the presence of additional benzyl structure. This review will give the overview on chemo preventive of ITCs against several types of cancer cell lines. We have also discussed the molecular interaction(s) of the antagonistic effect of BITC, PEITC and SFN with Nrf2 and NF-κB to prevent cancer.

scholarly journals Advancing environmental public health in Latin America and the Caribbean

2021 ◽  
Vol 45 ◽  
pp. 1
Author(s):  
Marcelo Korc ◽  
Fred Hauchman
Keyword(s):  
Public Health ◽  
Latin America ◽  
Health Sector ◽  
Well Being ◽  
Leadership Role ◽  
The Public ◽  
Environmental Public Health ◽  
The Caribbean ◽  
Health And Well Being

This paper highlights the important leadership role of the public health sector, working with other governmental sectors and nongovernmental entities, to advance environmental public health in Latin America and the Caribbean toward the achievement of 2030 Sustainable Development Goal 3: Health and Well-Being. The most pressing current and future environmental public health threats are discussed, followed by a brief review of major historical and current international and regional efforts to address these concerns. The paper concludes with a discussion of three major components of a regional environmental public health agenda that responsible parties can undertake to make significant progress toward ensuring the health and well-being of all people throughout Latin America and the Caribbean.

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