scholarly journals Is EEG a Useful Examination Tool for Diagnosis of Epilepsy and Comorbid Psychiatric Disorders?

2020 ◽  
Author(s):  
Hideki Azuma

Diagnosis of epilepsy usually involves interviewing the patients and the individuals who witnessed the seizure. An electroencephalogram (EEG) adds useful information for the diagnosis of epilepsy when epileptic abnormalities emerge. EEG exhibits nonlinearity and weak stationarity. Thus, nonlinear EEG analysis may be useful for clinical application. We examined only about English language studies of nonlinear EEG analysis that compared normal EEG and interictal EEG and reported the accuracy. We identified 60 studies from the public data of Andrzejak 2001 and two studies that did not use the data of Andrzejak 2001. Comorbid psychiatric disorders in patients with epilepsy were not reported in nonlinear EEG analysis except for one case series of comorbid psychotic disorders. Using a variety of feature extraction methods and classifier methods, we concluded that the studies that used the data of Andrzejak 2001 played a valuable role in EEG diagnosis of epilepsy. In the future, according to the evolution of artificial intelligence, deep learning, new nonlinear analysis methods, and the EEG association with the rating scale of the quality of life and psychiatric symptoms, we anticipate that EEG diagnosis of epilepsy, seizures, and comorbid psychiatric disorders in patients with epilepsy will be possible.

Author(s):  
Saurabh Jaiswal ◽  
Santosh Kumar

ABSTRACT Introduction People with epilepsy are more likely than the general population to have comorbid psychiatric disorders that include anxiety, depression, and interictal and chronic psychoses. Even though psychiatric comorbidity is common in epilepsy, it is underrecognized and undertreated, both in specialty epilepsy centers and also in community-based services. A thorough assessment of this was sought in this study among the patients of Rohilkhand region of Uttar Pradesh (India). Materials and methods A total of 100 patients with epilepsy who visited the psychiatry outpatient clinic were recruited for this study. They were assessed in detail for the presence of comorbid psychiatric disorders on Axis 1 with the help of Structured Clinical Interview for Fourth Edition of the Diagnostic and Statistical Manual of Mental Disorders. Results Overall, it was found that a comorbidity of psychiatric disorders was present in 45% of patients with epilepsy. The frequency of cooccurrence of different types of psychiatric disorders was as follows: Mood disorders 21%, anxiety disorders 14%, and psychotic disorders 28%. Conclusion Psychiatric comorbidities were found to be a common problem in patients with epilepsy. The results of this study are in line with many different research works both in India and abroad. A proper address of this issue is important for management, better outcome, and policy making in patients with epilepsy. How to cite this article Jaiswal S, Kumar S, Sharma CS, Kuchhal A, Jaiswal A. Psychiatric Comorbidities in Patients with Epilepsy: A Cross-sectional Study. Int J Adv Integ Med Sci 2017;2(1):24-28.


2021 ◽  
Vol 15 ◽  
Author(s):  
Irena Balzekas ◽  
Vladimir Sladky ◽  
Petr Nejedly ◽  
Benjamin H. Brinkmann ◽  
Daniel Crepeau ◽  
...  

Intracranial electroencephalographic (iEEG) recordings from patients with epilepsy provide distinct opportunities and novel data for the study of co-occurring psychiatric disorders. Comorbid psychiatric disorders are very common in drug-resistant epilepsy and their added complexity warrants careful consideration. In this review, we first discuss psychiatric comorbidities and symptoms in patients with epilepsy. We describe how epilepsy can potentially impact patient presentation and how these factors can be addressed in the experimental designs of studies focused on the electrophysiologic correlates of mood. Second, we review emerging technologies to integrate long-term iEEG recording with dense behavioral tracking in naturalistic environments. Third, we explore questions on how best to address the intersection between epilepsy and psychiatric comorbidities. Advances in ambulatory iEEG and long-term behavioral monitoring technologies will be instrumental in studying the intersection of seizures, epilepsy, psychiatric comorbidities, and their underlying circuitry.


2021 ◽  
Vol 28 (1) ◽  
Author(s):  
Sheikh Shoib ◽  
Javid Ahmad ◽  
Manzoor Ahmed Wani ◽  
Irfan Ullah ◽  
Shah Faisal Ahmad Tarfarosh ◽  
...  

Abstract Background The aim of the present study was to compare the presence of psychiatric disorders in people with hyperthyroidism and euthyroid patients attending the Endocrinology Outpatient Department at the Shri Maharaja Hari Singh Hospital in Kashmir, India. Seventy-five patients with hyperthyroidism and an equal number of euthyroid patients participated in the study. Participants were selected using stratified random sampling. All patients were female. There was no significant difference between the two groups in terms of demographic features. Hormonal screening was performed by immunoassay and haemagglutination method. For the mental health assessment, the Mini-International Neuropsychiatric Interview (MINI), Hamilton Depression Rating Scale [HAM-D], and Hamilton Anxiety Rating Scale [HAM-A] were used. Results There was a higher prevalence of psychiatric disorders among the hyperthyroidism group (60% versus 34.7%). In particular, there was a higher prevalence of major depressive disorder, suicidality, generalised anxiety disorder, panic attacks, and agoraphobia. In some cases, the prevalence of a psychiatric disorder diminished after endocrinological treatment. Conclusions Screening patients with hyperthyroid disorders for psychiatric symptoms and disorders, and providing timely care when necessary, can go a long way in improving the quality of life of this population. It is imperative to establish routine screening and timely care of mental health symptoms and disorders in patients with hyperthyroidism.


2010 ◽  
Vol 22 (5) ◽  
pp. 223-227 ◽  
Author(s):  
Fernando Machado Dias ◽  
Flávia Doyle ◽  
Arthur Kummer ◽  
Francisco Cardoso ◽  
Leonardo Franklin Fontenelle ◽  
...  

Dias FM, Doyle F, Kummer A, Cardoso F, Fontenelle LF, Teixeira AL. Frequency of psychiatric disorders in blepharospasm does not differ from hemifacial spasm.Objective:To compare the frequency of psychiatric disorders and the severity of psychiatric symptoms between patients with blepharospasm (BS) and hemifacial spasm (HS).Methods:BS is a type of primary focal dystonia characterised by recurrent and involuntary eye blinking. HS is a condition with different pathophysiology but similar clinical phenotype. Twenty-two patients with BS and 29 patients with HS participated in this study. They underwent a comprehensive psychiatric evaluation that included a structured clinical interview for current psychiatric diagnosis according to Diagnostic Statistical Manual, fourth edition (DSM-IV) (MINI-Plus) and psychometric scales, including the Yale-Brown Obsessive-Compulsive Scale (YBOCS), the Beck Depression Inventory (BDI), the Hamilton Rating Scale for Depression (HRSD), the Hamilton Anxiety Scale (HAS) and the Liebowitz Social Anxiety Scale (LSAS).Results:BS and HS groups did not differ in most demographic and clinical parameters, such as gender, age and length of symptoms. The frequency of psychiatric disorders and the severity of psychiatric symptoms were similar in both groups.Conclusion:BS does not seem to have more psychiatric disorders than HS.


Author(s):  
Kumari Padma ◽  
Sagar Subhash Nanaware ◽  
Aruna Yadihal ◽  
P. John Mathai

Background: Psoriasis is associated with a variety of psychological problems including poor self-esteem, sexual dysfunction, anxiety and depressive disorder and suicidal ideation. There are reports that patients with psoriasis may have significant psychiatric morbidity. The objective of the study is to evaluate the frequency of psychiatric disorders, frequency and nature of psychiatric symptoms in patients with psoriasis.Methods: 100 patients with psoriasis were evaluated and included for the study. Comprehensive Psychopathological Rating Scale (CPRS) is used for assessment of psychiatric symptoms and MINI Plus for assessing psychiatric disorders. Chi-square test was used to compare the proportions.Results: Patients with psoriasis had high frequency of psychiatric morbidity and was found to be 42%.Conclusions: Patients with psoriasis have more psychopathology and higher psychiatric morbidity which may further imply justifiable consultation liaison psychiatry in other speciality fields like Dermatology.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1277-1277
Author(s):  
M. Roca ◽  
S. Armengol ◽  
M. García-García ◽  
J. Salva ◽  
S. Monzón ◽  
...  

BackgroundDepression is associated with high rates of comorbidity with other psychiatric disorders. Adherence to antidepressant medication regimens has been associated to different factors. Few studies have analyzed the influence of comorbid psychiatric disorders and adjunctive pharmacological treatments on antidepressant adherence.AimThe study evaluates the association of comorbid psychiatric disorder and pharmacological treatments with adherence rates to antidepressants in a large sample of depressive outpatients.Method3606 depressive patients were included in a cross-sectional epidemiological study, involving a stratified sample of 750 psychiatrists selected to participate. Patients were included if they met DSM-IV criteria for current single or recurrent non-psychotic major depressive disorder. Simplified Medication Adherence Questionnaire (SMAQ) and Hamilton Depression Rating Scale (HDRS) were used to assess adherence and depression severity.ResultsAdherence rates are lower in depressive patients with psychiatric comorbidity (62.8%) than in patients without comorbidity (69.1%) (Chi-square = 15.9, p < 0.001, OR = 1.6, 1.2–1.8). There are no significant differences in adherence rates between those patients taking or not benzodiacepines.ConclusionsPsychiatric comorbidity plays a negative role in adherence to antidepressant treatment. Benzodiazepine use has no influence on adherence rates. Special attention should be paid to the symptom overlapping between anxiety and depression and to the benzodiazepine prescription in comorbid depressive patients.


2021 ◽  
Vol 12 ◽  
Author(s):  
Elise Riquin ◽  
Thomas Le Nerzé ◽  
Natwin Pasquini ◽  
Magalie Barth ◽  
Clément Prouteau ◽  
...  

Background: Mitochondrial disorders (MD) are a group of clinically heterogeneous genetic disorders resulting from dysfunction of the mitochondrial respiratory chain. Cognitive impairment is a common feature in adults with MD and psychiatric symptoms are associated with MD in up to 70% of the adult population. The aim of this study is to describe the psychiatric profile in children and adolescents with MD by focusing on the description of psychiatric symptoms.Methods: A cohort of 12 children and adolescents was prospectively recruited between February 2019 and February 2020 in the Reference Center for Mitochondrial Disorders of Angers (France). Participants and their parents completed an anamnestic form to provide socio-demographic data and completed the Global Assessment of Functioning scale, the Brief Psychiatric Rating Scale, the Child Depression Inventory, the Revised Children's Manifest Anxiety Scale, and the Conner's Rating Scale to evaluate the inattention/hyperactivity symptoms as well as the Quality of Life scale.Results: Four children (33.3%) were diagnosed with depressive symptoms. With regarding to anxiety, 6 children (50%) reported anxiety issues during the psychiatric interview and 3 children (25%) were suffering from anxiety according to the RCMAS scale. Compared to other children with chronic illnesses, the individuals in our cohort reported a lower overall quality of life score and lower scores in physical and social subscales.Conclusion: Our study shows that MD can lead to psychiatric disorders in children and adolescents, in particular anxiety and depression, as well as poor quality of life. This highlights the need for regular psychiatric assessments in individuals with developing brains, such as children and adolescents. We do not, however, have data regarding the neuropsychological profile of this population.


2017 ◽  
Vol 41 (S1) ◽  
pp. S354-S354 ◽  
Author(s):  
H.P. Caglar Nazali ◽  
E.A. Yildirim

The attachment style is one of the significant factors affecting the grief process and complicated grief. This study aims to research the relation between the factors determining the sociodemographic features, the reactions of grief, the suicidal behaviour and the grief process on the patients who are followed and treated with the complicated grief diagnosis and the features of attachment. The study includes 45 patients directed to a therapy unit and meet the criterions of complicated grief diagnosis. 33 of those patients have completed their treatment. Sociodemographic and clinical data form applied to the patients at the beginning, to evaluate for comorbid psychiatric disorders structured clinical interview for DSM-IV axis I disorders, adult attachment style questionnaire (AASQ), grief scale, hamilton rating scale for depression (HDRS), suicide behaviors questionnaire (SBQ), suicide probability scale (SPS), experiences in close relationships inventory (ECRI) are applied on the participants and compared the results of the scales prior to and following the treatment. In the dimensional evaluation of attachment, ECRI avoidance score is high over the patients diagnosed with comorbid psychiatric disorders with complicated grief. During the first application of the treatment, while evaluating the attachment categorically, in the complicated grief patients attached with avoidance grief scale, behavioural base scale and SPS negative self base scale are higher compared to the group whose HDRS scores attached with secure. The results show that in complicated grief cases the avoidance attachment is both dimensionally and categorically related with the strength of grief reaction and additional psychiatric problems.Disclosure of interestThe authors have not supplied their declaration of competing interest.


Crisis ◽  
2005 ◽  
Vol 26 (4) ◽  
pp. 160-169 ◽  
Author(s):  
Paul S. Links ◽  
Rahel Eynan ◽  
Jeffrey S. Ball ◽  
Aiala Barr ◽  
Sean Rourke

Abstract. Assertive community treatment appears to have limited impact on the risk of suicide in persons with severe and persistent mental illness (SPMI). This exploratory prospective study attempts to understand this observation by studying the contribution of suicidality to the occurrence of crisis events in patients with SPMI. Specifically, an observer-rated measure of the need for hospitalization, the Crisis Triage Rating Scale, was completed at baseline, crisis occurrence, and resolution to determine how much the level of suicidality contributed to the deemed level of crisis. Second, observer-ratings of suicidal ideation, the Modified Scale for Suicide Ideation, and psychopathology and suicidality, Brief Psychiatric Rating Scale, were measured at baseline, crisis occurrence, and resolution. A self-report measure of distress, the Symptom Distress Scale, was completed at baseline, crisis occurrence, and resolution. Finally, the patients' crisis experiences were recorded qualitatively to compare with quantitative measures of suicidality. Almost 40% of the subjects experienced crisis events and more than a quarter of these events were judged to be severe enough to warrant the need for hospitalization. Our findings suggest that elevation of psychiatric symptoms is a major contributor to the crisis occurrences of individuals with SPMI; although the risk of suicide may have to be conceived as somewhat separate from crisis occurrence.


2018 ◽  
Vol 59 (2) ◽  
pp. 176-186 ◽  
Author(s):  
Sheila N. Garland ◽  
Ivan Vargas ◽  
Michael A. Grandner ◽  
Michael L. Perlis

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