Adherence to antidepressant treatment in depressive patients with comorbid psychiatric disorders

2011 ◽  
Vol 26 (S2) ◽  
pp. 1277-1277
Author(s):  
M. Roca ◽  
S. Armengol ◽  
M. García-García ◽  
J. Salva ◽  
S. Monzón ◽  
...  
Keyword(s):  
Psychiatric Disorders ◽  
Psychiatric Comorbidity ◽  
Rating Scale ◽  
Antidepressant Treatment ◽  
Antidepressant Medication ◽  
Pharmacological Treatments ◽  
Chi Square ◽  
Cross Sectional ◽  
Comorbid Psychiatric Disorders ◽  
Depressive Patients

BackgroundDepression is associated with high rates of comorbidity with other psychiatric disorders. Adherence to antidepressant medication regimens has been associated to different factors. Few studies have analyzed the influence of comorbid psychiatric disorders and adjunctive pharmacological treatments on antidepressant adherence.AimThe study evaluates the association of comorbid psychiatric disorder and pharmacological treatments with adherence rates to antidepressants in a large sample of depressive outpatients.Method3606 depressive patients were included in a cross-sectional epidemiological study, involving a stratified sample of 750 psychiatrists selected to participate. Patients were included if they met DSM-IV criteria for current single or recurrent non-psychotic major depressive disorder. Simplified Medication Adherence Questionnaire (SMAQ) and Hamilton Depression Rating Scale (HDRS) were used to assess adherence and depression severity.ResultsAdherence rates are lower in depressive patients with psychiatric comorbidity (62.8%) than in patients without comorbidity (69.1%) (Chi-square = 15.9, p < 0.001, OR = 1.6, 1.2–1.8). There are no significant differences in adherence rates between those patients taking or not benzodiacepines.ConclusionsPsychiatric comorbidity plays a negative role in adherence to antidepressant treatment. Benzodiazepine use has no influence on adherence rates. Special attention should be paid to the symptom overlapping between anxiety and depression and to the benzodiazepine prescription in comorbid depressive patients.

scholarly journals Psychopathology in patients with psoriasis: a cross-sectional clinical study

2019 ◽  
Vol 8 (1) ◽  
pp. 307
Author(s):  
Kumari Padma ◽  
Sagar Subhash Nanaware ◽  
Aruna Yadihal ◽  
P. John Mathai
Keyword(s):  
Psychiatric Disorders ◽  
Rating Scale ◽  
Psychiatric Symptoms ◽  
Psychiatric Morbidity ◽  
Self Esteem ◽  
Liaison Psychiatry ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Consultation Liaison Psychiatry

Background: Psoriasis is associated with a variety of psychological problems including poor self-esteem, sexual dysfunction, anxiety and depressive disorder and suicidal ideation. There are reports that patients with psoriasis may have significant psychiatric morbidity. The objective of the study is to evaluate the frequency of psychiatric disorders, frequency and nature of psychiatric symptoms in patients with psoriasis.Methods: 100 patients with psoriasis were evaluated and included for the study. Comprehensive Psychopathological Rating Scale (CPRS) is used for assessment of psychiatric symptoms and MINI Plus for assessing psychiatric disorders. Chi-square test was used to compare the proportions.Results: Patients with psoriasis had high frequency of psychiatric morbidity and was found to be 42%.Conclusions: Patients with psoriasis have more psychopathology and higher psychiatric morbidity which may further imply justifiable consultation liaison psychiatry in other speciality fields like Dermatology.

scholarly journals Faktor-Faktor yang Berhubungan dengan Tekanan Darah pada Masa Pandemi Covid-19

2020 ◽  
Vol 5 (2) ◽  
pp. 61-67
Author(s):  
Widiharti Widiharti ◽  
Wiwik Widiyawati ◽  
Widya Lita Fitrianur
Keyword(s):  
Rating Scale ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Hamilton Anxiety Rating Scale ◽  
Hamilton Anxiety

Tekanan darah adalah faktor penting dalam sistem sirkulasi tubuh manusia. Tekanan darah dapat dengan mudah berubah meski dalam hitungan detik (Sasmalinda, Syafriandi, & Helma, 2013). Pada 2 Maret 2020, pemerintah Indonesia pertama kali mengumumkan dua kasus pasien postif Covid-19. (Pranita, 2020). Pasien tidak berani melakukan pemeriksaan ke rumah sakit, sehingga jika ada keluhan yang tidak begitu berat mereka akan membeli obat di apotik tanpa mengetahui tekanan darahnya. Hal ini sangat mengkhawatirkan karena tekanan darah yang tidak terkontrol dapat menyebabkan komplikasi lain seperti stroke. Tujuan penelitian menganalisis faktor yang berhubungan dengan tekanan darah. Desain penelitian analitik observasional, dengan pendekatan Cross Sectional (Notoatmodjo, 2012). Pelaksanaan bulan  Maret – Mei 2020. Populasi dari Seluruh warga  babatan RT 8 RW 2 Kelurahan Babatan Kecamatan Wiyung sebanyak 110 orang. Teknik Sampel total sampling. Variabel independen; jenis kelamin, beban kerja, pendapatan, tingkat kecemasan dan riwayat keluarga. Variabel dependen; tekanan darah. Instrument penelitian; timbangan injak digital, tensi digital, dan kuesioner. Variabel Tingkat kecemasan  menggunakan HARS (Hamilton Anxiety Rating Scale). Dianalisis uji statistik Chi Square dengan nilai p value <0.05. Hasil penelitian chi square  beban kerja nilai p-value 0,004<0,005 ada hubungan beban kerja dengan  tekanan darah. Hasil  p – value 0,002<0,05 ada hubungan antara jenis kelamin dengan tekanan darah.  Hasil p value 0,463<0,05 tidak ada hubungan antara tingkat kecemasan, hasilnya p – value 0,000<0,05 ada hubungan riwayat keluarga dengan tekanan darah. Kesimpulan faktor yang berhubungan dengan tekanan darah yaitu jenis kelamin, beban kerja, pendapatan, riwayat keluarga sedangkan faktor yang tidak berhubungan dengan tekanan darah yaitu kecemasan

scholarly journals Relationship of psychiatric comorbidity and treatment of panic disorder and agoraphobia

2006 ◽  
Vol 134 (7-8) ◽  
pp. 267-272
Author(s):  
Milan Latas ◽  
Vladan Starcevic ◽  
Goran Trajkovic
Keyword(s):  
Panic Disorder ◽  
Psychiatric Disorders ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Psychiatric Comorbidity ◽  
Integrative Model ◽  
Treatment Modalities ◽  
Cognitive Behavior ◽  
Comorbid Psychiatric Disorders ◽  
Relationship Of

Introduction. Besides numerous studies that examined various aspects of comorbidity in patients with panic disorder and agoraphobia and numerous studies that examined efficacy of different treatment modalities in these patients, there was no study that examined relationship of overall psychiatric comorbidity and treatment of patients with panic disorder and agoraphobia. Objective. The objective of the study was to establish the effect of psychiatric comorbidity on treatment efficiency of patients with panic disorder and agoraphobia. Method. The sample of the study consisted of 119 patients with primary diagnosis of panic disorder and agoraphobia. The therapy of patients was based on the use of individual integrative model of treatment, which incorporated psycho-pharmaceuticals (benzodiazepines and antidepressants) and cognitive- behavior therapy. Symptom severity was estimated by Panic and Agoraphobia Scale before and after the completion of treatment. Patients with comorbidity and patients without any comorbidity were compared by MANOVA and ANOVA with repeated measures. Results. The results of the study showed that 91% of patients met diagnostic criteria of comorbid psychiatric disorder and these patients had more severe clinical picture than patients without any comorbid disorder before the treatment. The results also showed that, after the completion of treatment, there was a significant reduction of all analyzed symptoms, that the effects of treatment were significantly better in patients with psychiatric comorbidity and that comorbid psychiatric disorders had no negative effect on the main goals of the treatment. Conclusion. Based on these results, it may be concluded that: in patients with panic disorder and agoraphobia and comorbid psychiatric disorders, the pharmacotherapy must be based on simultaneous use of antidepressants and benzodiazepines, while standard cognitive-behavior therapy of patients with panic disorder and agoraphobia must be modified in case of the existing comorbid psychiatric disorders.

scholarly journals Hubungan tingkat kecemasan dengan kualitas tidur pada ibu hamil irimester III di Socokangsi Jatinom Klaten

2019 ◽  
Vol 3 (1) ◽  
pp. 27-32
Author(s):  
Piscolia Dynamurti Wintoro ◽  
Wiwin Rohmawati ◽  
Ana Sulistyowati
Keyword(s):  
Sleep Quality ◽  
Quality Index ◽  
Rating Scale ◽  
Pittsburgh Sleep Quality Index ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Hamilton Rating Scale

Latar Belakang: Seorang ibu hamil biasa mengalami kecemasan. Pada TM III kecemasan disebabkan oleh kekhawatiran menghadapi persalinan dan apakah bayinya lahir normal atau cacat. Kecemasan meningkatkan kadar norepinefrin dalam darah melalui stimulasi sistem saraf simpatis. Perubahan kimia ini menyebabkan kurangnya waktu tidur tahap IV NREM dan tidur REM serta lebih banyak perubahan dalam tahap tidur lain dan lebih sering terbangun. Tujuan penelitian ini adalah untuk mengetahui hubungan tingkat kecemasan dengan kualitas tidur pada ibu hamil trimester III di BPM Siti Sujalmi Socokangsi Jatinom. Metode: Desain penelitian deskriptif korelasional dengan pendekatan cross sectional. Populasi penelitian ini ibu hamil trimester III di BPM Siti Sujalmi Socokangsi Jatinom, sebanyak 40 responden dengan teknik total sampling. Alat pengambilan data menggunakan kuesioner Hamilton Rating Scale For Anxiety (HRS-A) untuk mengukur tingkat kecemasan dan Pittsburgh Sleep Quality Index (PSQI) untuk mengukur kualitas tidur. Analisis data yang digunakan chi square. Hasil : Penelitian ini menunjukkan ada hubungan tingkat kecemasan dengan kualitas tidur pada ibu hamil trimester III di BPM Siti Sujalmi Socokangsi dengan P value sebesar 0,021. Simpulan : Ibu hamil trimester III dapat memperbaiki kualitas tidur dengan mengurangi aktivitas dan istirahat yang cukup, perasaan cemas dengan cara relaksasi, senam ibu hamil, dan yoga.

scholarly journals Antidepressants: knowledge and use among nursing students

2010 ◽  
Vol 18 (3) ◽  
pp. 421-428 ◽  
Author(s):  
Plínio Tadeu Istilli ◽  
Adriana Inocenti Miasso ◽  
Cláudia Maria Padovan ◽  
José Alexandre Crippa ◽  
Carlos Renato Tirapelli
Keyword(s):  
Nursing Students ◽  
Antidepressant Treatment ◽  
Antidepressant Medication ◽  
Descriptive Study ◽  
The State ◽  
Antidepressant Therapy ◽  
Nursing School ◽  
Therapeutic Effects ◽  
Cross Sectional ◽  
Antidepressant Medications

This study examined the knowledge of nursing students in regard to using antidepressant medication and proposes actions such that nurses contribute to a safe and effective antidepressant therapy. This cross-sectional and descriptive study was conducted in a public nursing school in the state of São Paulo, Brazil, between March and November 2008. Fifty-two (19%) out of the 273 participants were using or had used antidepressants. Instruction concerning the use of antidepressants was provided by physicians. Even after receiving instruction concerning the antidepressant treatment before its administration, the majority of users (cII1=0.07, p> 0.05) still had doubts about its use. Fluoxetine was the most prevalent antidepressant. Actions to improve knowledge concerning the use of antidepressant medications, their side and therapeutic effects, seem to be necessary and relevant.

Psychiatric Comorbidities in Patients with Epilepsy: A Cross-sectional Study

2017 ◽  
Vol 2 (1) ◽  
pp. 24-28
Author(s):  
Saurabh Jaiswal ◽  
Santosh Kumar
Keyword(s):  
Psychiatric Disorders ◽  
Psychotic Disorders ◽  
Uttar Pradesh ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Psychiatric Comorbidities ◽  
Comorbid Psychiatric Disorders ◽  
Diagnostic And Statistical Manual ◽  
Patients With Epilepsy

ABSTRACT Introduction People with epilepsy are more likely than the general population to have comorbid psychiatric disorders that include anxiety, depression, and interictal and chronic psychoses. Even though psychiatric comorbidity is common in epilepsy, it is underrecognized and undertreated, both in specialty epilepsy centers and also in community-based services. A thorough assessment of this was sought in this study among the patients of Rohilkhand region of Uttar Pradesh (India). Materials and methods A total of 100 patients with epilepsy who visited the psychiatry outpatient clinic were recruited for this study. They were assessed in detail for the presence of comorbid psychiatric disorders on Axis 1 with the help of Structured Clinical Interview for Fourth Edition of the Diagnostic and Statistical Manual of Mental Disorders. Results Overall, it was found that a comorbidity of psychiatric disorders was present in 45% of patients with epilepsy. The frequency of cooccurrence of different types of psychiatric disorders was as follows: Mood disorders 21%, anxiety disorders 14%, and psychotic disorders 28%. Conclusion Psychiatric comorbidities were found to be a common problem in patients with epilepsy. The results of this study are in line with many different research works both in India and abroad. A proper address of this issue is important for management, better outcome, and policy making in patients with epilepsy. How to cite this article Jaiswal S, Kumar S, Sharma CS, Kuchhal A, Jaiswal A. Psychiatric Comorbidities in Patients with Epilepsy: A Cross-sectional Study. Int J Adv Integ Med Sci 2017;2(1):24-28.

scholarly journals Hubungan lamanya hemodialisis dengan tingkat depresi pada pasangan hidup pasien gagal ginjal kronik di RSUP Prof. Dr. R. D. Kandou Manado

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Vicka V. A. Tartum ◽  
Theresia M. D. Kaunang ◽  
Christofel Elim ◽  
Neni Ekawardani
Keyword(s):  
Rating Scale ◽  
Chronic Renal Disease ◽  
Chronic Kidney Failure ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Loved One ◽  
Hamilton Depression Rating Scale ◽  
Chi Square Analysis ◽  
The Impact

Abstract: Depression is a disturbance in the function of human nature associated with feelings of sadness and accompanying symptoms, including changes in sleep patterns and appetite, anhedonia, concentration, psychomotor, fatigue, despair and helplessness. Depression can be obtained by any person, including a person suffering from chronic diseases such as chronic renal disease requiring hemodialysis therapy for life. However, the impact of depression was not only felt by the patient, but also the patient's family, especially spouses of patients would be very easy to get depressed as a result of seeing a loved one suffer, so will affect the support and motivation given to patients, especially in patients undergoing hemodialysis should undergo dialysis for life, so a lot of depression in patients and their families, especially spouses of patients. This study aimed to determine the relationship of the length of hemodialysis with the level of depression in spouses of hemodialysis patients in Prof. Dr. R. D. Kandou Hospital Manado. This was an observational analystical study with a cross sectional design. This study used Hamilton Depression Rating Scale questionaire (HDRS). Data were processed by using SPSS 20.0. The chi-square analysis test showed a p value of 0.105 (p > 0.05). Conclusion: There was no correlation between the duration of hemodialysis with the degree of depression of chronic kidney failure patient’s live spouses.Keywords: depression, chronic kidney disease, hemodialysis, spouse.Abstrak: Depresi adalah terganggunya fungsi manusia yang berkaitan dengan alam perasaan yang sedih dan gejala penyertanya, termasuk perubahan pada pola tidur dan nafsu makan, anhedonia, konsentrasi, psikomotor, kelelahan rasa putus asa dan tidak berdaya. Depresi bisa didapatkan oleh setiap orang termasuk seseorang yang menderita penyakit kronik seperti penyakit ginjal kronik yang membutuhkan terapi hemodialisis seumur hidup. Dampak depresi pun tidak hanya dirasakan oleh pasien, keluarga pasien terutama pasangan hidup pasien akan sangat mudah mendapatkan depresi akibat melihat orang yang dicintai menderita, sehingga akan memengaruhi dukungan dan motivasi yang akan diberikan kepada pasien, terutama pada pasien yang menjalani hemodialisis yang harus menjalani proses cuci darah seumur hidup, sehingga banyak terjadi depresi pada pasien dan keluarganya terutama pasangan hidup pasien. Penelitian ini bertujuan untuk mengetahui hubungan lamanya hemodialisis dengan tingkat depresi pada pasangan hidup pasien hemodialisis di RSUP Prof. Dr. R. D. Kandou Manado. Metode penelitian yang digunakan ialah analitik observasional dengan pendekatan potong lintang. Penelitian ini menggunakan kuesioner Hamilton Depression Rating Scale (HDRS) dan data diolah menggunakan SPSS 20.0. Uji analisis chi-square mendapatkan nilai p sebesar 0,105 (p >0,05). Simpulan: Tidak terdapat hubungan antara lama hemodialisis dengan tingkat depresi pasangan hidup pasien penyakit ginjal kronik.Kata kunci: depresi, penyakit ginjal kronik, hemodialisis, pasangan hidup

scholarly journals Prevalence of Psychiatric Disorders in Patients Referring to a Psychiatric Clinic in Lorestan Province, West of Iran

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Hedayat Nazari ◽  
Mandana Saki ◽  
Sajad Yarahmadi ◽  
Zoherh Mohammadi
Keyword(s):  
Mental Health ◽  
Psychiatric Disorders ◽  
Mood Disorders ◽  
Cross Sectional Study ◽  
Psychiatric Clinic ◽  
Chi Square ◽  
Cross Sectional ◽  
Education Group ◽  
Promotion Policies ◽  
Chi Square Test

Background: Psychiatric disorders are common and impose a huge burden globally. The study aimed to examine the prevalence of psychiatric disorders in patients referring to a psychiatric clinic in Lorestan. Objectives: This study aimed to investigate the prevalence of psychiatric disorders in patients referring to a psychiatric clinic in Lorestan province Methods: A cross-sectional study was conducted with all people aged 18 years or older. Participants were selected by a convenience sampling method. Diagnostic interviews based on DSM-5 were held for 750 patients who were administered between January and June 2018. The collected data were analyzed by SPSS version 22 using absolute frequency, relative frequency, mean, and chi-square test. Results: Women included 53% of the study sample. The most prevalent psychiatric disorders were anxiety (35.3%) and mood disorders (31.5%). Depression was the most prevalent mood disorder (63.6%), followed by generalized anxiety disorder (60%). The prevalence of psychiatric disorders was higher in people aged 21-30 (28.5%), the illiterate or primary education group (52.4%), housekeepers (29.5%), and married ones (51.8%). Conclusions: The majority of the patients referring to the psychiatric clinic suffered from mood and anxiety disorders. Therefore, public health authorities of the province need to take steps to warrant necessary measures, including mental health promotion policies, to improve the mental health status and prevent anxiety and mood disorders.

scholarly journals Hubungan intensitas pemakaian gawai dengan neck pain pada usia 15-20 tahun

2019 ◽  
Vol 2 (2) ◽  
pp. 71-76
Author(s):  
Yuni Tri Yustianti ◽  
Pusparini Pusparini
Keyword(s):  
Neck Pain ◽  
Rating Scale ◽  
Numeric Rating Scale ◽  
Chi Square ◽  
Cross Sectional ◽  
Numeric Rating

LATAR BELAKANG Dekade terakhir menunjukkan neck pain pada remaja semakin meningkat, bersamaan dengan meningkatnya penggunaan gawai (gadget). Seiring perkembangan zaman, gawai menjadi kebutuhan dan gaya hidup masyarakat luas. Pelajar menjadi pasar terbesar dalam penggunaan gawai sehubungan dengan kebutuhan belajar yang memerlukan akses Internet. Salah satu faktor penyebab neck pain pada pengguna gawai adalah intensitas penggunaan gawai yang mempengaruhi lamanya posisi fleksi pada otot leher. Tujuan penelitian ini adalah untuk mengetahui hubungan intensitas pemakaian gawai dengan neck pain pada usia 15-20 tahun. METODE Penelitian ini merupakan studi observasional dengan desain cross sectional yang mengikutsertakan 164 pelajar SMAN 28 Jakarta dan Fakultas Hukum Universitas Trisakti. Data dikumpulkan dengan cara pengisian kuesioner yang meliputi usia, jenis kelamin, intensitas pemakaian gawai dan keluhan neck pain. Penilaian neck pain menggunakan NRS (Numeric Rating Scale). Analisis data dilakukan dengan uji Chi-square dengan tingkat kemaknaan p<0.05. HASIL Subjek perempuan berjumlah 121 orang (73.8%). Paparan gawai dengan intensitas >56 jam/minggu dijumpai pada 109 subjek (66.5%). Keluhan neck pain dijumpai pada 138 subjek (84.1%). Uji Chi-square menunjukkan terdapat hubungan yang bermakna antara intensitas penggunaan gawai dengan neck pain pada usia 15-20 tahun dengan nilai p=0.004. KESIMPULAN Terdapat hubungan yang bermakna antara intensitas penggunaan gawai dengan neck pain pada usia 15-20 tahun.    

Correlations Between Neuroendocrine Disorders and Biochemical Brain Metabolites Alterations in Antidepressant Treatment

2018 ◽  
Vol 69 (3) ◽  
pp. 621-626
Author(s):  
Luminita Ageu ◽  
Cristina Talpos ◽  
Ghizela Kanalas ◽  
Simina Crisan ◽  
Carmen Lacramioara Zamfir ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Mr Spectroscopy ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Antidepressant Treatment ◽  
Treatment Strategies ◽  
Antidepressant Medication ◽  
Brain Metabolites ◽  
Gamma Aminobutyric Acid ◽  
Pharmacogenetic Testing

We approach the theme of modern investigation and treatment strategies, based on biochemical, clinical-biological, metabolic, pharmacogenetic, neuro-imagistic, and neuroendocrine integrative correlations in the management of depressive disorders. Our main objective was to investigate: the biochemical brain metabolites [N-acetyl-aspartate (NAA), gamma-aminobutyric acid (GABA), aspartate (Asp), creatine (CR), glutamine (Gln), glicerophosphocholine (GPC), phosphocholine (PC), phosphocreatine (PCr), taurine (Tau), N-methyl-D-aspartate (N-MDA), serine, glycine, choline (Cho)]; the neuroimagistic and neurobiological markers and the metabolic abnormalities in correlation with the molecular pharmacogenetic testing in children and adolescents treated with antidepressant medication. Our research was conducted between 2009-2016 on 90 children and adolescents with depressive disorders -45 children-G1, who benefited of pharmacogenetic testing tailored pharmacotherapy, and 45 without pharmacogenetic testing-G2. The patients were also evaluated by MR spectroscopy at baseline and after pharmacotherapy. The efficacy of the chosen therapy in correlation with the pharmacogenetic testing was evaluated by the mean change in the CDRS (Child Depression Rating Scale) total scores, in the CGI-S/I (Clinical Global Impression Severity/Improvement), CGAS (Clinical Global Assessment of Functioning) and by the change of the relevant neurobiological markers and MR spectroscopy biochemical brain metabolites. Our results showed statistically significant differences in the clinical scores between the studied groups. Our research could represent a proof that the biochemical brain metabolites registered in depressive disorders modified values in the MR spectroscopy and the administration of antidepressants could determine metabolic and neuroendocrine abnormalities (changed lipid profiles, high insulin and plasma glucose levels, weight gain, obesity), especially when chosen without prior pharmacogenetic testing.

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