scholarly journals Pityriasis lichenoides et varioliformis acuta in skin of color: new observations by dermoscopy

2017 ◽  
Author(s):  
Balachandra S. Ankad ◽  
Savitha L. Beergouder
Keyword(s):  
Late Phase ◽  
Case Series ◽  
Hair Follicles ◽  
Pityriasis Lichenoides ◽  
Medical College ◽  
Inflammatory Conditions ◽  
Case Series Study ◽  
Duration Of Disease ◽  
San Juan Capistrano ◽  
Histologic Changes

Background: Pityriasis lichenoides is an uncommon skin disease that presents in three different forms: pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic-Mucha-Habermann disease. These represent a spectrum of a disease. PLEVA presents as skin eruption of multiple, small, red papules that develop into polymorphic lesions with periods of varying remissions, as well as possible sequels of hyper/hypopigmentation and varicella-like scars. Diagnosis of this condition is mainly clinical, and sometimes clinical differentiation from other conditions may be a difficult task that often requires histological analysis. In this study, PLEVA lesions were examined by dermoscopy, and the significance of specific dermoscopic findings was investigated in order to facilitate their differentiation from other inflammatory conditions. Objectives: To evaluate dermoscopic patterns in PLEVA and to correlate these patterns with histopathology. Materials and methods: The study was conducted at S. Nijalingappa Medical College, Bagalkot. It was an observational case series study and patients were selected randomly. Ethical clearance and informed consent were obtained. PLEVA lesions in early and late phases were evaluated. A manual DermLite 3 (3Gen, San Juan Capistrano, CA) dermoscope attached to a Sony (Cyber Shot DSC-W800, Sony Electronics Inc., San Diego, California, USA, digital, 14 mega pixels) camera was employed. Histopathology was done to confirm the diagnosis. Data was collected and analyzed. Results were statistically described in terms of frequencies and types of dermoscopic patterns. Results: There was a total of 14 patients; 8 males and 6 females. Mean age of patients was 19 years. Mean duration of disease was 7 months. Dermoscopy in early-phase lesions revealed amorphous brownish areas around the hair follicles, dotted vessels, and scaling. Dermoscopy in late-phase lesions showed whitish-structureless areas and central white crust within whitish-structureless rim with scale, focal bluish-grayish areas or centrifugal strands irregularly distributed along the periphery and yellow structures. Red dots and hemorrhage were seen at the center and glomerular vessels at the periphery. Conclusion: PLEVA demonstrates specific dermoscopic patterns that correlate well with histologic changes. New dermoscopic findings are described. Thus, dermoscopy is a good diagnostic tool in the clinical diagnosis of PLEVA.  

scholarly journals PATIENTS WITH CONVERSION DISORDER

2010 ◽  
Vol 17 (04) ◽  
pp. 715-720
Author(s):  
NIAZ MAQSOOD ◽  
BUSHRA AKRAM ◽  
WAJID ALI
Keyword(s):  
Life Events ◽  
Stressful Life Events ◽  
Case Series ◽  
Strong Relationship ◽  
Conversion Disorder ◽  
Stressful Life ◽  
Psychosocial Stressors ◽  
Medical College ◽  
Case Series Study ◽  
Series Study

Objectives: To assess the frequency of the various psychosocial stressors and stressful life events in patients presenting with conversion disorder. Study Design: Case series study. Place & Duration of Study: The study was conducted in the Department of Psychiatry & Behavioural Sciences, Bahawal Victoria Hospital & Quaid-e-Azam Medical College, Bahawalpur from January, 2009 to March, 2009. Subjects & Methods: The sample consisted of 100 in-patients (89 Female, 11 Male) with Conversion Disorder. They were interviewed andresults were analysed from the entries in a Performa. Results: Stressors were clearly identified in 100 patients. In all patients, we found more than one stressor. Among patients, there were (24%) In-laws problems, (23%) Love problems, (21%) Relationship problems with family, (20%) exam/study stress, (15%) marriage against will, (13%) demanding and pampered child, (11%) Issue less, (10%) sexual abuse, (8%) demand of marriage, (6%) overage in wait of marriage, (4%) death of partner, (3%) husband abroad and (3%) patient’s engagement break. Conclusions: We concluded that stressors and life events were present in all conversion disorder’s patients and these stressful life events are important causal factors for Conversion Disorder. Conversion Disorder has strong relationship with psychosocial stressors. 

scholarly journals Pediatric Septic Shock: Early Recognition and Aggressive Fluid Therapy Improves Outcome

2019 ◽  
pp. 1-6
Author(s):  
Shahzad Najeeb ◽  
Shabana Sarwar ◽  
Rafayat Ullah ◽  
Asfandyar . ◽  
Khurram Saleem ◽  
...  
Keyword(s):  
Septic Shock ◽  
Early Recognition ◽  
Fluid Management ◽  
Case Series ◽  
Generation Cephalosporin ◽  
Medical College ◽  
Case Series Study ◽  
Study Participants ◽  
Age Range ◽  
Series Study

Objective: To establish the effect of aggressive fluid resuscitation in reversing the pediatric septic shock at 1 hour in children younger than 5 years of age presenting in the emergency unit of the hospital. Methods:  This was a descriptive, case series study, done for six months, from December 2015 to May 2016, at Pediatric Department of Ayub Medical College Abbottabad. Patients with age range of 1 month to 5 years, presenting in the emergency department with the diagnosis of septic shock having clinical features of tachycardia, tachypnea or hyperthermia along with hypotension and poor capillary refill time were included. All patients received aggressive fluid management. Clinical examination was repeated at the end of one hour for assessment of reversal of shock. Data was collected by self-made Performa. Results: Mean age of study participants was 22.4 ± 17.6 months. Majority of participants 42(57%) were male. Mean weight was 10.3±4.3 kilograms. Mean heart rate was 173.9±17.8 beats per minutes. 67.6% were treated with a third-generation cephalosporin. At the end of one hour of treatment 51 (68.9%) showed the reversal of shock. Conclusion: Majority of childrens who presented with septic shock showed the reversal of shock at one hour of management with weight-based fluid bolus therapy.

scholarly journals SEVERITY OF SNAKE BITE WITH EARLY PREDICTORS OF THROMBOCYTOPENIA AND ALBUMINURIA IN ACUTE KIDNEY INJURY

2020 ◽  
pp. 1-3
Author(s):  
Ashmitha Padma ◽  
Pramila Devi
Keyword(s):  
Acute Kidney Injury ◽  
Serum Creatinine ◽  
Case Series ◽  
Kidney Injury ◽  
P Value ◽  
Medical College ◽  
Urine Albumin ◽  
Early Predictors ◽  
Case Series Study ◽  
Prospective Case Series

Snakebites are very common public health problems which is caused by venomous arthropods effecting many organs and causing fatal emergencies. Snakebite can cause direct or indirect nephro toxicity, especially hematotoxic snakebites. It is important to know the early predictors of acute kidney injury so as to prevent the complications early. Methods: This is a prospective case series study conducted at S. Nijalingappa Medical College and Hangal Shri Kumareshwar Hospital and Research center, Bagalkot from June 2018 to June 2019. Results: Total of 51 patients were included in this study who satisfied the inclusion and exclusion criteria. It was found that 35 patients had thrombocytopenia with p value of <0.002, which was highly significant. Serum creatinine was found to be more than 1.2mg/dl in 35 patients and the p value was <0.002 which was highly significant and urine albumin was also found to be more which p avalue was<0.001. among the study subjects 70% of them were found to have thrombocytopenia with albuminuria and increase in serum creatinine.

A HISTOLOGICAL STUDY OF LIVER IN PATIENTS DIAGNOSED AS FATTY LIVER ON ULTRASOUND

JKCD ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 5-8
Author(s):  
Shabnum Aamir
Keyword(s):  
Fatty Liver ◽  
Histological Study ◽  
Case Series ◽  
Mean Value ◽  
Morphometric Study ◽  
Alcoholic Fatty Liver ◽  
Medical College ◽  
Case Series Study ◽  
Normal Mean ◽  
Liver Biopsies

Objectives: To confirm sonographic findings of fatty liver by histologic study of liver biopsies and to look for related histological changes associated with fatty liver.Material and method: It was case series study. The study was conducted in Gastroenterology unit of Hayatabad Medical Complex, Histology lab of Khyber Medical College Peshawar. The study period was five months. Ten cases labeled as fatty liver on Ultrasonography were designated for liver biopsy proceeded by microscopic study. The patients with advanced liver disease were excluded. Tissue slides were observed under light microscope. The morphometric measurements were carried out. Histological Scoring System for non-alcoholic fatty liver diseases was applied for histological staging and grading. Results: Microscopic examination showed that the mean value of size of hepatocytes and nuclei were significantly more than normal mean. 50% of total cases were with panacinar steatosis, zone 1 and zone 3 steatosis were noted in 20% and 30% of patients respectively. Ballooning was revealed in all the cases, while lobular inflammation was seen in 60% of patients. All of the cases depict various phases of fibrosis, but Cirrhosis could not be noticed in any of the specimen. 30% of the cases were recorded with definite non-alcoholic steatotic hepatitis (NASH), 50% were labelled as borderline NASH and 20% were as simple steatosis. Conclusions: All cases detected as simple fatty liver on ultrasonography are found with some degree of steatosis and steatohepatitis on histological examination. Morphometric study showed that steatotic process increases hepatocytes and nuclei size. Ballooning and lobar inflammation were the hallmark of NASH

scholarly journals Obstetric Near Miss Events in a Tertiary Research Level Teaching Hospital

Med Phoenix ◽  
2017 ◽  
Vol 2 (1) ◽  
pp. 44-47
Author(s):  
Tarannum Khatun ◽  
Zarin Rahman ◽  
Nuzhat Parveen ◽  
Akhtar Alam Ansari ◽  
Mohammed Islam Mansuri ◽  
...  
Keyword(s):  
Case Series ◽  
Near Miss ◽  
Hypertensive Disorder ◽  
Surgical Interventions ◽  
Medical College ◽  
National Medical ◽  
Positive Elements ◽  
Case Series Study ◽  
Obstetric Services ◽  
Emergency Hysterectomy

Background: Objective of the study was to identify the important causes of near miss cases and to evaluate the key interventions for the management and ultimate maternal outcome.Material and methods: In this case series study, critically ill pregnant, laboring or postpartum women who were admitted either directly or through referral to the National Medical College, Birgunj, Nepal, formed the study group. The women who escaped death due to medical or surgical interventions were categorized as Near Miss. These cases were defined based on WHO Criteria 2009.Results: There were 2424 births during this year and 33 were near miss cases. The bulk of these were directly admitted to our hospital (23 cases). The most common condition leading to this dreadful condition was hemorrhage, acute severe hypertensive disorder (preeclampsia/eclampsia) and sepsis. Disseminated Intravascular Coagulation was found to be the most common organ dysfunction. Emergency hysterectomy was the most frequent surgical intervention used to prevent mortality.Conclusion: Maternal Near Miss review is a viable review as it has potential to highlight the deficiency as well as positive elements of obstetric services in any health system. Hemorrhage followed by hypertensive disorders are the leading causes of near miss events.Med Phoenix Vol.2(1) July 2017, 44-47

scholarly journals MATERNAL MORTALITY 2007-2008

2010 ◽  
Vol 17 (02) ◽  
pp. 291-294
Author(s):  
AISHA ABDULLAH SHAIKH ◽  
SADIA SABOOHI ◽  
RUBINA A D MEMON
Keyword(s):  
Maternal Mortality ◽  
Tertiary Care ◽  
Maternal Mortality Ratio ◽  
Case Series ◽  
Medical College Hospital ◽  
Contributing Factors ◽  
College Hospital ◽  
Maternal Deaths ◽  
Medical College ◽  
Case Series Study

Objectives: To analyse the maternal mortality with its causes and possible contributing risk factors at Ghulam Mohammad Mahar Medical College Hospital, Sukkur. Setting: This study was carried out at Gynae / Obs Unit-1 of Ghulam Mohammad Mahar Medical College Hospital, Sukkur from Jan-2007 to Dec-2008. Study Design: Descriptive case series study. Subjects and Methods: This study was conducted by analysing the death records of all maternal deaths who died over a period of two (02) years from Jan 2007 to Dec 2008. Thedemographic record included age, parity, booking status and education. The cause of death and possible contributing factors were evaluated. Results: 48 mothers died during this period making Maternal Mortality Ratio (MMR) of 1578/ 100,000 live births. Direct causes contributed to 79% (38) of maternal deaths while 21% (10) were due to indirect causes. The major causes of deaths were eclampsia 27% (13), haemorrhage33% (11), Sepsis 21% (10), Obstructed labour 8% (4). Among indirect causes, hepatic encethalopathy, anemia and renal failure were observed. Conclusions: Eclampsia, haemorrhage and Sepsis are still the major killers. Factors which need urgent improvement include education, antenatal booking, early diagnosis and referrals to tertiary care centers.

scholarly journals CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM

2010 ◽  
Vol 17 (01) ◽  
pp. 101-104
Author(s):  
HAJI KHAN KHOHARO ◽  
F ATI MA QURESHI ◽  
SHUAIB ANSARI ◽  
Rizwan Javed
Keyword(s):  
Plasmodium Falciparum ◽  
Case Series ◽  
Acute Attack ◽  
Chloroquine Resistance ◽  
Inclusion Criteria ◽  
Medical College ◽  
Case Series Study ◽  
Age Range ◽  
Series Study ◽  
Line Drug

Objective: The study was conducted to determine the frequency of Chloroquine-resistant Plasmodium falciparum. Subjects& Methods: This was a descriptive case series study conducted at Muhammad Medical College Mirpurkhas & Liaquat University HospitalHyderabad/ Jamshoro, from January 2007 to December 2007. Total 160 patients with acute attack of fever were selected & studied who fulfilledthe inclusion criteria. The WHO extended test was done by giving 25 mg/kg body weight of Chloroquine base over 3 days. The interpretationof the test was done as per criteria laid down by WHO. Results: Out of one hundred sixty, 110 (68.75%) were males and 50 (31.25%) werefemales with ratio of 2.2:1. The age range 16-45 years with mean 28±12 years. Seventy one patients (44.375%) were Chloroquine sensitive.Chloroquine-resistance (CQR) Rl, Rll & both Rl Rll noted were 28.125%, 15.645% & 43.75% respectively. The CQR- R III was not observedin our study. Conclusions: In view of this situation, more organized and thorough studies must be conducted to elucidate the epidemiology,geographic-distribution & degree of Chloroquine resistance. And the local strategies be made to overcome this problem and to assess the needfor changing the first line drug.

scholarly journals An Observational Study on Immune-related Disorders and Their Treatment Response in Ayurveda- Case Series

2021 ◽  
pp. 199-207
Author(s):  
K. Pradeep ◽  
M. Abhilash ◽  
M. A. Reshma ◽  
Bindu K. Viswambaran
Keyword(s):  
Allergic Rhinitis ◽  
Case Series ◽  
Holistic Approach ◽  
Blood Parameters ◽  
Medical College ◽  
Immune Parameters ◽  
Case Series Study ◽  
Before And After ◽  
Ayurvedic Treatment ◽  
Allergic Disorders

Immune-related disorders are common health problems in the world. Based on the principal immunologic mechanism they are classified into four types. One of the four types includes immediate hypersensitivity which is an IgE antibody and mast cell-mediated reaction. Ayurvedic treatments have sometimes delivered good results in the treatment of these disorders. This work is a humble effort to streamline Immune-related diseases in the settings of Govt Ayurveda Medical College, Tripunithura, Kerala, India. In this case series study patients with allergic rhinitis and urticaria were selected. Their symptoms and blood parameters were assessed both before and after the Ayurvedic treatment for one month. In both allergic rhinitis and urticaria, there was a significant reduction in the symptoms. In the case of blood investigations, only IgE showed a significant change in allergic rhinitis. Even though Ayurvedic immunology has a strong potential to treat allergic disorders with its pro-nature individualized holistic approach to make significant changes in immune parameters administration of rejuvenators for more than one month is very essential.

scholarly journals Pathar dye (paraphenyldiamine) poisoning: our experience of this lethal emerging health problem in a tertiary care centre

2017 ◽  
Vol 3 (4) ◽  
pp. 1056
Author(s):  
Shivani Nautiyal ◽  
Shashwat Tiwari ◽  
Kumar Ashutosh
Keyword(s):  
Health Problem ◽  
Public Awareness ◽  
Tertiary Care ◽  
Case Series ◽  
Medical Emergency ◽  
Tertiary Care Centre ◽  
Hair Dye ◽  
Medical College ◽  
Case Series Study ◽  
Initial Symptoms

<div class="page" title="Page 1"><div class="section"><div class="layoutArea"><div class="column"><p class="abstract"><strong>Background:</strong> The aim of this case series study is to share our experiences regarding paraphenylenediamine (PPD) poisoning, its otolaryngological clinical presentation ,outcomes and need of tracheostomy in patients of hair dye poisoning at GSVM Medical College, Kanpur, U.P.</p><p class="abstract"><strong>Methods:</strong> This prospective study was carried out on 165 patients who presented in GSVM medical college Kanpur in period of December 2012 till December 2014. Data including demographic features (age, sex, marital status, socio-economic status), clinical features, laboratory findings, mode of intoxication (accidental or suicide) were collected and recorded.  </p><p class="abstract"><strong>Results:</strong> A majority of the patients were young females (21-30 years) and belonged to a low socioeconomic class. The main cause was intentional suicidal ingestion. Cervicofacial edema, stridor, hoarseness of voice and pain in throat were initial symptoms. Tracheostomy was needed in 115 (69.69%) patients. Mortality of 21 (12.72%) patients was observeds.</p><p><strong>Conclusions:</strong> It is a major emerging health problem with high mortality. It is a medical emergency and early intervention is needed to save patient's life. It is imperative to raise public awareness of the potential toxicity of the dye as well as to educate physicians about the need for aggressive and early treatment. </p></div></div></div></div>

Force Plate Analysis of Dogs with Bilateral Hip Dysplasia Treated with a Unilateral Triple Pelvic Osteotomy: A Long-term Review of Cases

1998 ◽  
Vol 11 (02) ◽  
pp. 85-93 ◽  
Author(s):  
Joanne R. Cockshutt ◽  
H. Dobson ◽  
C. W. Miller ◽  
D. L. Holmberg ◽  
Connie L. Taves ◽  
...  
Keyword(s):  
Gait Analysis ◽  
Hip Dysplasia ◽  
Weight Bearing ◽  
Force Plate ◽  
Case Series ◽  
Pelvic Osteotomy ◽  
Vertical Force ◽  
Long Term Outcome ◽  
Case Series Study

SummaryA retrospective case series study was done to determine the long-term outcome of operations upon dogs treated for canine hip dysplasia by means of a triple pelvic osteotomy (TPO). Twentyfour dogs with bilateral hip dysplasia, that received a unilateral TPO between January 1988 and June 1995, were re-examined at the Ontario Veterinary College. The assessment included physical, orthopedic and lameness examinations, standard blood work, pelvic radiographs and force plate gait analysis. They were compared to bilaterally dysplastic dogs that had not been treated, and also to normal dogs. Force plate data analysis demonstrated a significant increase in peak vertical force (PVF) and mean vertical force over stance (MVF) in the limb that underwent surgical correction by means of a TPO, when compared to the unoperated hip. It was determined that performing a unilateral TPO on a young dysplastic dog resulted in greater forces and weight bearing being projected through the TPO corrected limb when compared to the unoperated limb.Dogs with bilateral hip dysplasia treated with a unilateral triple pelvic osteotomy (TPO) were assessed by force plate gait analysis, radiographs and orthopedic examination. There was a significant increase in hip Norberg angles over time, although degenerative changes did progress. Limbs that had been operated upon had significantly greater peak and mean ground reaction forces than limbs that had not received an operation.

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