scholarly journals In vitro antibiotic resistance patterns of Pseudomonas spp. isolated from clinical samples of a hospital in Madinah, Saudi Arabia

2018 ◽  
Vol 12 (1) ◽  
pp. 19-26 ◽  
Author(s):  
M. Saeed Walaa ◽  
Ghanem Samah ◽  
M. El Shafey Hatem ◽  
Manzoor Nikhat
Keyword(s):  
Saudi Arabia ◽  
Antibiotic Resistance ◽  
Clinical Samples ◽  
Pseudomonas Spp ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

scholarly journals Incidence of ?-lactamase producing Escherichia coli amongst clinical isolates in Dhaka, Bangladesh

2016 ◽  
Vol 5 (1) ◽  
pp. 18-21
Author(s):  
Anindita Bhowmik ◽  
Sunjukta Ahsan ◽  
Marufa Zerin Akhtar ◽  
Md Shahidul Kabir
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Point Of View ◽  
Clinical Isolates ◽  
Clinical Samples ◽  
Drug Of Choice ◽  
Resistance Patterns ◽  
Lactam Antibiotic ◽  
Antibiotic Resistance Patterns

Escherichia coli is one of the most important clinical pathogens that demonstrate antibiotic resistance through their ? -lactamase activity. The present study reflected on the presence of ?-lactam antibiotic resistance in clinical samples. Antibiotic resistance patterns of 20 clinical isolates of Escherichia coli against ? -lactam antibiotics were investigated. These isolates were collected from a hospital in Dhaka city and MIC values were determined against Imipenem, Cefotaxime and Ceftriaxone. In case of Ceftriaxone the highest MIC was >4096 ?g/mL for 50% isolates with a minimum MIC of 1 ?g/ml for 10% isolates. In case of Cefotaxime, MIC values ranged between 1 ?g/ml and >4096 ?g/ml for 20% and 10% isolates, respectively. In contrast, 80% of the isolates had an MIC of Imipenem at 1 ?g/mL with only 5% isolate having MIC of 8 ?g/mL. Eight out of 20 (40%) isolates were ESBL producers, 14 (70%) were ? -lactamase producers. Two isolates exhibited ESBL activity against Cefotaxime and Ceftriaxone, 3 against only Cefotaxime and 3 against only Ceftriaxone. Ceftriaxone resistance in 10 randomly picked isolates was found to be stable for 21days in stability assay. Considering the findings of the present study, it appears that Imipenem still remains the drug of choice for E. coli infections; alternatively, combination therapy may be prescribed. In vitro stability of Ceftriaxone resistance raises concern from a public health point of view as this may aid antibiotic resistance transfer to other bacteria in the environment.Stamford Journal of Microbiology, Vol.5(1) 2015: 18-21

scholarly journals Trends in antibiotic resistance patterns of methicillin resistant and methicillin sensitive Staphylococcus aureus in Khwaja Yunus Ali Medical College Hospital

KYAMC Journal ◽  
2018 ◽  
Vol 9 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Abdullah Akhtar Ahmed ◽  
Md Abdus Salam ◽  
Md Shakhaowat Hossain ◽  
Md Babul Aktar ◽  
Nusrat Akhtar Juyee ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Antimicrobial Resistance ◽  
Pathogenic Bacteria ◽  
Current Status ◽  
Clinical Samples ◽  
Sensitivity Testing ◽  
Methicillin Resistant ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

Background: Antimicrobial resistance in pathogens is a growing concern for health. It is a great concern around the globe about the threat of increasing antimicrobial resistance. In response to this concerns, medical experts have proposed initiatives to curtail the spread of antimicrobial resistance in pathogenic bacteria. We have taken this surveillance study in KYAMCH to contain the spread of antimicrobial resistance.Objectives: To determine the prevalence of MRSA from different clinical samples and to record its current status to commonly used anti Staphylococcus antibiotics.Methods: The clinical samples were taken to the laboratory and within four hours cultured for isolates and identification pathogens. Finally, antibiotic sensitivity testing of the isolated Staphylococcus aureus was performed. Results: More than 80% of MRSA isolates were resistant to ampicillin (98%) followed by amoxicillin, cefixime and azithromycin with 94%, 93.5% and 85% respectively and maximum sensitivity toward tobramycin with 86% followed by 85% gentamicin and 79% meropenem.Conclusion: The detected trend in antibiotic resistance patterns of methicillin-resistant and methicillin-sensitive Staphylococcus aureus in this study is alarming. This has created a huge clinical burden in the hospital settings as well as in the community.KYAMC Journal Vol. 9, No.-1, April 2018, Page 6-10

scholarly journals Transmission of infectious drug resistance from animals to man

1973 ◽  
Vol 71 (1) ◽  
pp. 209-215 ◽  
Author(s):  
D. M. Wells ◽  
O. B. James
Keyword(s):  
Drug Resistance ◽  
Antibiotic Resistance ◽  
Antibiotic Treatment ◽  
Farm Animals ◽  
Antibiotic Resistant ◽  
R Factor ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns ◽  
R Factors

SUMMARYThe antibiotic resistance patterns of coliforms in faecal specimens from pigs and their human contacts were studied. The ability of the resistant coliforms to transfer their resistance in vitro to antibiotic-sensitive recipients was examined. The results showed that pigs which had received antibiotics carried more multiply-resistant, R-factor bearing coliforms than pigs which had not been given antibiotics. Human contacts of the antibiotic-treated pigs had a higher incidence of antibiotic-resistant coliforms with R-factors than human contacts of pigs which had not been given antibiotics. It is concluded that antibiotic treatment of farm, animals may lead to acquisition of antibiotic resistance by gut coliforms of man.

scholarly journals Antibiotic Resistance Patterns in a University Hospital in Al-Kharj City

2019 ◽  
pp. 1-5
Author(s):  
Nehad J. Ahmed ◽  
Mohd F. Khan
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Resistance ◽  
Treatment Guidelines ◽  
Resistance Rate ◽  
University Hospital ◽  
Antimicrobial Drugs ◽  
E Coli ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

Introduction: Antibiotics are medications that are used to kill a bacterium which causes different infections. The misuse of these medications has contributed to the development of bacterial resistance. In order to predict the efficacy of the antimicrobial drugs and to guide antimicrobial therapy, antibiogram should be used. Objective: This study aims to explore the Antibiotic resistance patterns in a university hospital in AL-kharj city. Methods: Data from a university hospital in Al-Kharj city were used to assess the in vitro antimicrobial susceptibility rates for different types of bacteria. We included all bacterial and fungal cultures in the last 2 years. Results: The most common bacterium was E. coli and the most common fungus pathogen was Candida albicans. There was a low resistance rate to gentamicin, imipenem, meropenem and amikacin for the studied bacteria pathogens and high resistance rate for some antibiotics such as erythromycin, tetracycline and ampicillin. Conclusion: The physicians should follow the treatment guidelines and they should know the susceptibility rate of different bacteria to prescribe antibiotics appropriately.

scholarly journals Antibiotic Resistance Patterns of Pseudomonas spp. Isolated from the River Danube

2016 ◽  
Vol 7 ◽  
Author(s):  
Clemens Kittinger ◽  
Michaela Lipp ◽  
Rita Baumert ◽  
Bettina Folli ◽  
Günther Koraimann ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Pseudomonas Spp ◽  
River Danube ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

scholarly journals ESBL expression and antibiotic resistance patterns in a hospital in Saudi Arabia: Do healthcare staff have the whole picture?

2020 ◽  
Vol 13 (5) ◽  
pp. 759-766
Author(s):  
Fatimah A. Aldrazi ◽  
Ali A. Rabaan ◽  
Shahab A. Alsuliman ◽  
Hebah A. Aldrazi ◽  
Mohammed J. Alabdalslam ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Antibiotic Resistance ◽  
Healthcare Staff ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns

scholarly journals Molecular Analysis of KPC and GES Beta-Lactamase Genes in Clinical Isolates of Klebsiella pneumoniae by PCR Method

2021 ◽  
Vol 8 (2) ◽  
pp. 01-08
Author(s):  
Zohreh Saltanatpour ◽  
Marzieh Saremi ◽  
Leila Saremi ◽  
Sepideh Babaniamansour ◽  
Razieh Nazari
Keyword(s):  
Antibiotic Resistance ◽  
Clinical Samples ◽  
Resistance Pattern ◽  
Klebsiella Pneumonia ◽  
Carbapenem Resistant ◽  
Appropriate Treatment ◽  
Resistance Patterns ◽  
Pcr Method ◽  
Resistant Strains ◽  
Antibiotic Resistance Patterns

Background: Carbapenem-resistant Klebsiella pneumonia (K. pneumoniae) has been recently identified as the major class of pathogens and the treatment became the biggest challenge in this bacterium. We assessed the antibiotic resistance patterns of K. pneumoniae, the frequency of resistant strains to imipenem, meropenem, and ertapenem, and the frequency of K. pneumoniae carbapenemases (KPC), and Guiana-Extended-Spectrum (GES) metallo-β-lactamase genes. Methods: The phenotypes of 200 strains of K. pneumonia, collected from 650 clinical samples, were isolating and identified in Qom, Iran. The antibiotic resistance pattern of the strains was analyzed against different antibiotics. The imipenem, meropenem, and ertapenem-resistant strains, were isolated and the frequency of KPC and GES genes were evaluated. Results: K. pneumoniae strains had different resistance patterns against various antibiotics. The isolated strains with the highest and lowest antibiotic resistance were related to ampicillin, and meropenem, respectively. Investigation of the KPC and GES β lactamase showed that none of 48 imipenem, meropenem, and ertapenem-resistance isolates had the KPC gene. In addition, the GES gene was detected in 3(2.7%) of 110 ceftazidime-resistant specimens. Conclusions: Carbapenem is useful in the treatment of K. pneumoniae infections. Due to the importance of the mechanisms of resistance is by β-lactamase genes, investigating the prevalence of β-lactamase genes can help to increase the necessity of choosing the appropriate treatment for K. pneumoniae.

Isolation of Beta-Lactamase Producing Genes (SHV, CTX-M1, CTX-M2, CTX-M3) in Escherichia coli Isolated from Pregnant Woman Patients

2020 ◽  
Author(s):  
Kolsoum Rezaie Kahkhaie ◽  
Ashrafali Rezaie Kehkhaie ◽  
Leili Rezaie Kahkhaie ◽  
Maryam Koochakzai ◽  
Khadijeh Rezaie Keikhaie ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Clinical Microbiology Laboratory ◽  
Beta Lactamase ◽  
Extended Spectrum Beta Lactamase ◽  
E Coli ◽  
Resistance Patterns ◽  
Causative Agents ◽  
Antibiotic Resistance Patterns

Background: In recent decades, extended spectrum beta-lactamase (ESBL) generating bacteria have increased universally. Among the most important causative agents of nosocomial infections throughout the world, Escherichia coli as main ESBL-producing bacteria are so highly regarded. Trends in the treatment of infections by such bacteria have led to a global concern.   Methods: All strains were cultured and identified by the Clinical Microbiology Laboratory and were recovered from blood and urine cultures. In-vitro presence of ESBL was confirmed with Clinical and Laboratory Standard Institute double disc and PCR for CTX-M1, CTM-M2, CTX-M3 method.   Results: The results of this study showed that Escherichia coli samples were resistant to AN (42.85%), GM (28.57%), AM (35.71%), AMC (35.71%), CZ (35.71%), and AZM (50%) antibiotics. While the most susceptible to antibiotic was ampicillin (64.28%), the least resistance to antibiotics was gentamicin.   Conclusion: The current situation of multiple bacterial antibiotic resistance has become a worrisome issue in UTI. Multi-drug-resistant E. coli can be readily encountered in hospital settings during daily clinical practice, and urologist should act timely. The management of such infections is extremely important for the future, with particular reference to prevention of new antibiotic resistance patterns.

Sign in / Sign up

Export Citation Format

Share Document