Pharmaceutical R&D Productivity: The Role of Alliance

2014 ◽  
Vol 20 (2) ◽  
Author(s):  
Sarah Kruse ◽  
Mark Slomiany ◽  
Rema Bitar ◽  
Sarah Jeffers ◽  
Mahmud Hassan
Keyword(s):  
Technology Policy ◽  
Generic Competition ◽  
Role Of Government ◽  
Profit Margins ◽  
Face To Face ◽  
The Public ◽  
Research Organizations ◽  
Perfect Storm

In recent years, the major research-intensive biopharmaceutical companies (big pharma) have come face to face with a perfect storm of eroding profit margins from blockbuster expiration and generic competition coupled with growing R&D expenses and declining advances in truly novel therapeutics. With long-term research divisions shed in favor of short-term outsourcing options and with public good will at historic lows, industry innovators have sought to reinvent the model of big pharma, its relationship in public-private partnerships, and the role of technology and technology policy in reform. In this paper, we highlight a number of the major alliances reshaping the industry and the role of government, research institutions, and other players in the public-private interface in these endeavors. In particular, this paper looks beyond traditional biotechnology parternships and focuses instead on the developing consortia between biopharmaceutical companies and with clinical research organizations and academic institutions. We examined each alternative model of alliance, identified specific hurdles and potentials for increased productivity.

scholarly journals STUDY ON THE MECHANISM AND DILEMMA OF COMMUNITY PROMOTING EMPLOYMENT ENTREPRENEURSHIP OF COLLEGE STUDENTS

2021 ◽  
Author(s):  
YINGYING ZHANG
Keyword(s):  
College Students ◽  
College Graduates ◽  
Public Affairs ◽  
Employment Policy ◽  
Role Of Government ◽  
The Public ◽  
Public Nature ◽  
New Ideas

The employment of college students has been a serious social problem in recent years, and it is also the focus of concern of tens of millions of families and countries. The long-term employment policy of our country has been dominated by market distribution to give full play to the role of government macro-control. Past studies have also focused on macro-system, middle-family and micro-individual aspects, but there are few studies on the community with public characteristics between the state and individuals. In June 2020, the notice on guiding and encouraging college graduates to urban and rural community employment entrepreneurship provides us with new ideas to think about college students' employment entrepreneurship from a community perspective. The public nature of the community determines that the community has a natural advantage in solving public affairs. This paper will start with this characteristic of the community and study the mechanism of promoting the employment and entrepreneurship of college students. This paper provides a new idea for the research of college students' employment entrepreneurship.

Approaches to Supporting Local and Community Development

2018 ◽  
Author(s):  
Liesel Mack Filgueiras ◽  
Andreia Rabetim ◽  
Isabel Aché Pillar
Keyword(s):  
Large Scale ◽  
Mining Company ◽  
The Sustainable Development ◽  
Social Partnership ◽  
The Public ◽  
Mining Investment ◽  
The Social ◽  
Corporate Social

Reflection about the role of community engagement and corporate social investment in Brazil, associated with the presence of a large economic enterprise, is the major stimulus of this chapter. It seeks to present how cross-sector governance can contribute to the social development of a city and how this process can be led by a partnership comprising a corporate foundation, government, and civil society. The concept of the public–private social partnership (PPSP) is explored: a strategy for building a series of inter-sectoral alliances aimed at promoting the sustainable development of territories where the company has large-scale enterprises, through joint efforts towards integrated long-term strategic planning, around a common agenda. To this end, the case of Canaã dos Carajás is introduced, a municipality in the State of Pará, in the Amazon region, where large-scale mining investment is being carried out by the mining company Vale SA.

Deliberation in Communication Studies

2018 ◽  
pp. 501-517
Author(s):  
John Gastil ◽  
Laura Black
Keyword(s):  
Critical Role ◽  
Ancient Greece ◽  
Communication Studies ◽  
Face To Face ◽  
The Public ◽  
Contemporary Work ◽  
Social Scientific ◽  
The Public Sphere

The discipline of communication encompasses a broad spectrum of humanistic, interpretive, and social scientific approaches to studying public deliberation. Early work engaged Habermasian theories of the public sphere, and rhetorical scholarship has foregrounded the deliberative threads running back to the discipline’s earliest history in ancient Greece. The bulk of contemporary work, however, has examined the dynamics of deliberation, particularly in the context of face-to-face discussions and dialogues in small groups. These studies have revealed the importance of narrative and dialogic exchanges during deliberation, as well as the critical role of facilitation and the maintenance of deliberative norms. Research has also assessed the practical consequences of participating in deliberation. The discipline’s practical orientation has led some scholars to seek ways to optimize deliberative designs to maximize simultaneously the quality of their decision outputs and their civic impacts on participants.

scholarly journals How are Kawaii (Cute) Fictional Characters Used in Japanese Advertising

2021 ◽  
Vol 14 (1 (39)) ◽  
pp. 55-78
Author(s):  
Oana-Maria BÎRLEA
Keyword(s):  
Egg Yolk ◽  
Cultural Dimensions ◽  
Fictional Characters ◽  
Japanese Company ◽  
The Public ◽  
Different Types ◽  
The Government ◽  
Commercial Advertising

This article aims to explain the use and role of cute, adora- ble characters in Japanese advertising. Kawaii culture or the “culture of cute” has become known worldwide mainly because of Hello Kitty, the cat which led the “pink globalization”, as Yano (2013) states. In this paper we have attempted to reveal the symbolism of these apparent meaning- less cute signs and characters. Starting from Hofstede’s theory of cultural dimensions (2001, 2003, 2010), which shows how a society’s culture influ- ences the values of its members, we intended to show how are these kawaii characters used in Japanese advertising and how they fit cultural specif- ics. Used either in non-commercial, educational or commercial advertising, cute personae can make the target audience feel more comfortable, secure and cooperating (Murakami, 2005). In this paper we have discussed the role of three iconic characters: the emblematic Hello Kitty, Kumamon, the lovely bear created by the government of Kumamoto Prefecture (Japan) and Gudetama, a lazy egg yolk produced by the Japanese company Sanrio in 2014. The selected characters reflect different types and personalities and each of them serves a specific purpose, but via the analysis conveyed we conclude that perhaps their main aim is to persuade and create a long-term relationship with the public.

scholarly journals APPLYING THE PRINCIPLES OF NEW PUBLIC MANAGEMENT TO MEASURE THE PERFORMANCE IN EDUCATION – VALUE FOR MONEY

2019 ◽  
Vol 2 (1) ◽  
pp. 50-57
Author(s):  
Jana Štrangfeldová ◽  
Štefan Hronec ◽  
Jana Hroncová Vicianová ◽  
Nikola Štefanišinová
Keyword(s):  
Public Management ◽  
New Public Management ◽  
Tertiary Education ◽  
Relevant Information ◽  
Value For Money ◽  
The Public ◽  
New Public ◽  
Comprehensive Measurement

Education is a key area, the results of which play an important role in the development of each society. The role of education focused on the inclusion of children into school groups, to prepare students to enter the labour market or continue their studies in the context of tertiary education is a sufficient argument to enable beginning to look for answers and possible solutions to the difficult question of the quality of schools. Constant pressure from the public forces them to monitor and improve the provision of public services, and continually enhance their own performance in order to achieve long-term existential security. These facts consequently require a comprehensive measurement of their performance. This opens up opportunities for applying the concept of Value For Money based on the principles of New Public Management. The purpose of the scientific study is to show the potential uses of Value for Money on the example of education. The suggestion of methodology of VFM to measure the performance in education presented in this study shows possibilities to measure, evaluate, monitor and achieve necessary and especially relevant information about the situation of education and subsequent decision-making not only for public forces, but also, it can be the suitable tool for public grammar schools themselves. The article is co-financed by the project VEGA 1/0651/17.

Conservation and Conservatism

2002 ◽  
Author(s):  
David W. Orr
Keyword(s):  
Eighteenth Century ◽  
Free Market ◽  
Social Institutions ◽  
The Political ◽  
Role Of Government ◽  
Political Field ◽  
Modern Conservatism ◽  
The Devil

The philosophy of free-market conservatism has swept the political field virtually everywhere, and virtually everywhere conservatives have been, in varying degrees, hostile to the cause of conservation. This is a problem of great consequence for the long-term human prospect because of the sheer political power of conservative governments. Conservatism and conservation share more than a common linguistic heritage. Consistently applied they are, in fact, natural allies. To make such a case, however, it is necessary first to say what conservatism is. Conservative philosopher Russell Kirk (1982, xv–xvii) proposes six “first principles” of conservatism. Accordingly, true conservatives:… • believe in a transcendent moral order • prefer social continuity (i.e., the “devil they know to the devil they don’t know”) • believe in “the wisdom of our ancestors” • are guided by prudence • “feel affection for the proliferating intricacy of long-established social institutions” • believe that “human nature suffers irremediably from certain faults.”… For Kirk the essence of conservatism is the “love of order” (1982, xxxvi). Eighteenth-century British philosopher and statesman Edmund Burke, the founding father of modern conservatism and as much admired as he is unread, defined the goal of order more specifically as one which harmonized the distant past with the distant future. To this end Burke thought in terms of a contract, but not one about “things subservient only to the gross animal existence of a temporary and perishable nature.” Burke’s societal contract was not, in other words, about tax breaks for those who don’t need them, but about a partnership promoting science, art, virtue, and perfection, none of which could be achieved by a single generation without veneration for the past and a healthy regard for those to follow. Burke’s contract, therefore, was between “those who are living, those who are dead, and those who are to be born . . . linking the lower with the higher natures, connecting the visible and invisible world” ([1790] 1986, 194–195). The role of government, those “possessing any portion of power,” in Burke’s words, “ought to be strongly and awefully impressed with an idea that they act in trust” (ibid., 190).

scholarly journals Forming “Mediators and Instruments of Grace”: The Emerging Role of Monastics in Teaching Contemplative Ambiguity and Practice to the Laity

Religions ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 405
Author(s):  
Paula Pryce
Keyword(s):  
Religious Community ◽  
Global Network ◽  
Centering Prayer ◽  
Face To Face ◽  
Teaching Role ◽  
Meditation Technique ◽  
Christian Meditation ◽  
Ways Of Being

Drawing from long-term ethnographic research with a global network of contemplative Christians, this paper discusses an emerging teaching role for North American monasteries as the numbers of avowed religious decline. Since the Trappist community of St. Joseph’s Abbey in Spencer, Massachusetts, first developed the Christian meditation technique called Centering Prayer in the 1970s, monks and nuns have increasingly become teachers, models, and stabilizers of non-monastic practitioners who attempt to transform their ways of being and thinking towards monastic-inspired sensibilities. Their guidance includes the use of face-to-face, literary, and virtual means to teach methods of contemplative intersubjectivity and a commitment to lives based on service, hospitality, and humility, as well as on study and formalized rites. The paper focuses on non-monastics’ strong attraction to monastic teachings on ambiguity as a source of creativity and wonder in uncertain times, as practiced through a combination of cataphatic and apophatic ritual, including Centering Prayer. The number of monastic postulants continues to falter, yet a much larger, “non-gathered” community of non-monastic oblates and neo-monastic contemplatives has grown increasingly reliant on monastics to help provide alternatives. The rising interdependence of monastics and non-monastics may become the basis of a transformation of Christian monasticism and a new concept of religious community.

Community Services: Contrasts Between Resident and Nonresident Landowners in the Adirondack Region of New York

1975 ◽  
Vol 4 (2) ◽  
pp. 132-142
Author(s):  
Robert G. Craig ◽  
Harry P. Mapp
Keyword(s):  
United States ◽  
New York ◽  
World War Ii ◽  
The United States ◽  
Community Services ◽  
World War ◽  
Revolutionary Change ◽  
Role Of Government ◽  
The Public

“There is more than enough evidence to show that the states and localities, far from being weak sisters, have actually been carrying the brunt of domestic governmental progress in the United States ever since the end of World War II … Moreover, they have been largely responsible for undertaking the truly revolutionary change in the role of government in the United States that has occurred over the past decade.”–Daniel J. Elazar, The Public Interest

Opioid Therapy for Chronic Nonmalignant Pain: Clinicians' Perspective

1996 ◽  
Vol 24 (4) ◽  
pp. 296-309 ◽  
Author(s):  
Russell K. Portenoy
Keyword(s):  
Psychosocial Functioning ◽  
Cumulative Risk ◽  
Opioid Therapy ◽  
Adverse Outcomes ◽  
The Public ◽  
The Past ◽  
Nonmalignant Pain ◽  
Chronic Nonmalignant Pain

During the past decade, debate has intensified about the role of long-term opioid therapy in the management of chronic nonmalignant pain. Specialists in pain management have discussed the issues extensively and now generally agree that a selected population of patients with chronic pain can attain sustained analgesia without significant adverse consequences. This perspective, however, is not uniformly accepted by pain specialists and has not been widely disseminated to other disciplines or the public. Rather, the more traditional perspective, which ascribes both transitory benefit and substantial cumulative risk to long-term opioid therapy, continues to predominate. According to this perspective, the inevitability of tolerance limits the possibility of sustained efficacy, and other pharmacological properties increase the likelihood of adverse outcomes, including persistent side-effects, impairment in physical and psychosocial functioning, and addiction. If accurate, these outcomes would indeed justify the withholding of opioid therapy for all but the most extreme cases of chronic nonmalignant pain.

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