The ‘Queen’s Shades’ and a ‘Gothicized’ London

2016 ◽  
pp. 148-174
Author(s):  
Susan Ash

This chapter explores how Barnardo uses the Gothic narrative mode as a central mechanism to raise affect and thus engage potential supporters. The discussion draws on Jamieson Ridenhour’s work on the Gothicised cityscape to explore how Barnardo’s London reflects societal anxieties related to the past and the potential degeneration of British citizenry. It focuses on Barnardo’s treatment of one site in London, ‘The Queen’s Shades’ a site formed by mounds of detritus at the old Billingsgate Fish Market, first in a novel Barnardo wrote and serialized in his juvenile periodicals, and secondly in a supposedly non-fictional account for adults which narrativized the beginnings of his work in the 1860s. Both raise crucial questions about thresholds and liminality, about borders between inside/outside, animate and inanimate, indeed, between human and not-human. The chapter argues that Barnardo uses the Gothic in the child’s narrative to excite and engage interest while eliciting fear and shame in the adult version. Ultimately, ‘The Queen’s Shades’ operates as a powerful Gothic trope in which human sensations, corporal bodies and architectural detritus merge to reflect societal fears regarding the stability of the wider English social body.

2020 ◽  
Vol 27 ◽  
Author(s):  
Sheetal Uppal ◽  
Mohd. Asim Khan ◽  
Suman Kundu

Aims: The aim of our study is to understand the biophysical traits that govern the stability and folding of Synechocystis hemoglobin, a unique cyanobacterial globin that displays unusual traits not observed in any of the other globins discovered so far. Background: For the past few decades, classical hemoglobins such as vertebrate hemoglobin and myoglobin have been extensively studied to unravel the stability and folding mechanisms of hemoglobins. However, the expanding wealth of hemoglobins identified in all life forms with novel properties, like heme coordination chemistry and globin fold, have added complexity and challenges to the understanding of hemoglobin stability, which has not been adequately addressed. Here, we explored the unique truncated and hexacoordinate hemoglobin from the freshwater cyanobacterium Synechocystis sp. PCC 6803 known as “Synechocystis hemoglobin (SynHb)”. The “three histidines” linkages to heme are novel to this cyanobacterial hemoglobin. Objective: Mutational studies were employed to decipher the residues within the heme pocket that dictate the stability and folding of SynHb. Methods: Site-directed mutants of SynHb were generated and analyzed using a repertoire of spectroscopic and calorimetric tools. Result: The results revealed that the heme was stably associated to the protein under all denaturing conditions with His117 playing the anchoring role. The studies also highlighted the possibility of existence of a “molten globule” like intermediate at acidic pH in this exceptionally thermostable globin. His117 and other key residues in the heme pocket play an indispensable role in imparting significant polypeptide stability. Conclusion: Synechocystis hemoglobin presents an important model system for investigations of protein folding and stability in general. The heme pocket residues influenced the folding and stability of SynHb in a very subtle and specific manner and may have been optimized to make this Hb the most stable known as of date. Other: The knowledge gained hereby about the influence of heme pocket amino acid side chains on stability and expression is currently being utilized to improve the stability of recombinant human Hbs for efficient use as oxygen delivery vehicles.


Catalysts ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 255
Author(s):  
Dien-Thien To ◽  
Yu-Chuan Lin

Copper phyllosilicates-derived catalysts (CuPS-cats) have been intensively explored in the past two decades due to their promising activity in carbonyls hydrogenation. However, CuPS-cats have not been completely reviewed. This paper focuses on the aspects concerning CuPS-cats from synthesis methods, effects of preparation conditions, and dopant to catalytic applications of CuPS-cats. The applications of CuPS-cats include the hydrogenation of carboxylates, carboxylic acids, carbonates, formyls, and CO2 to their respective alcohols. Besides, important factors such as the Cu dispersion, Cu+ and Cu0 surface areas, particles size, interaction between Cu and supports and dopants, morphologies, and spatial effect on catalytic performance of CuPS-cats are discussed. The deactivation and remedial actions to improve the stability of CuPS-cats are summarized. It ends up with the challenges and prospective by using this type of catalyst.


2020 ◽  
Vol 30 ◽  
pp. 77-96
Author(s):  
Sujit Sivasundaram

AbstractThe Pacific has often been invisible in global histories written in the UK. Yet it has consistently been a site for contemplating the past and the future, even among Britons cast on its shores. In this lecture, I reconsider a critical moment of globalisation and empire, the ‘age of revolutions’ at the end of the eighteenth century and the start of the nineteenth century, by journeying with European voyagers to the Pacific Ocean. The lecture will point to what this age meant for Pacific islanders, in social, political and cultural terms. It works with a definition of the Pacific's age of revolutions as a surge of indigeneity met by a counter-revolutionary imperialism. What was involved in undertaking a European voyage changed in this era, even as one important expedition was interrupted by news from revolutionary Europe. Yet more fundamentally vocabularies and practices of monarchy were consolidated by islanders across the Pacific. This was followed by the outworkings of counter-revolutionary imperialism through agreements of alliance and alleged cessation. Such an argument allows me, for instance, to place the 1806 wreck of the Port-au-Prince within the Pacific's age of revolutions. This was an English ship used to raid French and Spanish targets in the Pacific, but which was stripped of its guns, iron, gunpowder and carronades by Tongans. To chart the trajectory from revolution and islander agency on to violence and empire is to appreciate the unsettled paths that gave rise to our modern world. This view foregrounds people who inhabited and travelled through the earth's oceanic frontiers. It is a global history from a specific place in the oceanic south, on the opposite side of the planet to Europe.


2021 ◽  
Vol 13 (7) ◽  
Author(s):  
Alvie Loufouma Mbouaka ◽  
Michelle Gamble ◽  
Christina Wurst ◽  
Heidi Yoko Jäger ◽  
Frank Maixner ◽  
...  

AbstractAlthough malaria is one of the oldest and most widely distributed diseases affecting humans, identifying and characterizing its presence in ancient human remains continue to challenge researchers. We attempted to establish a reliable approach to detecting malaria in human skeletons using multiple avenues of analysis: macroscopic observations, rapid diagnostic tests, and shotgun-capture sequencing techniques, to identify pathological changes, Plasmodium antigens, and Plasmodium DNA, respectively. Bone and tooth samples from ten individuals who displayed skeletal lesions associated with anaemia, from a site in southern Egypt (third to sixth centuries AD), were selected. Plasmodium antigens were detected in five of the ten bone samples, and traces of Plasmodium aDNA were detected in six of the twenty bone and tooth samples. There was relatively good synchronicity between the biomolecular findings, despite not being able to authenticate the results. This study highlights the complexity and limitations in the conclusive identification of the Plasmodium parasite in ancient human skeletons. Limitations regarding antigen and aDNA preservation and the importance of sample selection are at the forefront of the search for malaria in the past. We confirm that, currently, palaeopathological changes such as cribra orbitalia are not enough to be certain of the presence of malaria. While biomolecular methods are likely the best chance for conclusive identification, we were unable to obtain results which correspond to the current authentication criteria of biomolecules. This study represents an important contribution in the refinement of biomolecular techniques used; also, it raises new insight regarding the consistency of combining several approaches in the identification of malaria in past populations.


2021 ◽  
Vol 13 (10) ◽  
pp. 5659
Author(s):  
Farhood Sarrafzadeh Javadi ◽  
Rahman Saidur

Refrigeration systems have experienced massive technological changes in the past 50 years. Nanotechnology can lead to a promising technological leap in the refrigeration industry. Nano-refrigerant still remains unknown because of the complexity of the phase change process of the mixture including refrigerant, lubricant, and nanoparticle. In this study, the stability of Al2O3 nanofluid and the performance of a nano-refrigerant-based domestic refrigerator have been experimentally investigated, with the focus on the thermodynamic and energy approaches. It was found that by increasing the nanoparticle concentration, the stability of nano-lubricant was decreased and evaporator temperature gradient was increased. The average of the temperature gradient increment in the evaporator was 20.2% in case of using 0.1%-Al2O3. The results showed that the energy consumption of the refrigerator reduced around 2.69% when 0.1%-Al2O3 nanoparticle was added to the system.


2021 ◽  
pp. 136248062110078
Author(s):  
Katja Franko

The Southern Mediterranean border has in the past decade become one of the most deeply contested political spaces in Europe and has been described as a site of the border spectacle. Drawing on textual and visual analysis of Twitter messages by two of the most prominent actors in the field, the European Border and Coast Guard Agency, Frontex, and the humanitarian and medical NGO Médecins Sans Frontières, the article examines the split nature of the Mediterranean border which is, among others, visible in radically different narratives about migrants’ journeys, border deaths and living conditions. The findings challenge previous scholarship about convergence of humanitarianism and policing. The two actors are waging a fierce media battle for moral authority, where they use widely diverging strategies of claiming authority, each of which carries a particular set of ethical dilemmas.


SAGE Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 215824402110335
Author(s):  
Tingting Hu ◽  
Tianru Guan

Through an in-depth analysis of gender representation in the box office record-breaking Chinese movie Wolf Warrior II, this study interrogates how the male body is used as a site for the projection of Chinese national power. Furthermore, it illustrates a revival of patriotic pride in China through a contemporary reading of cross-genre action-military films. Developing Shuqin Cui’s notion of “woman-as-nation,” which understands on-screen female victimization in Chinese films as signifying the past suffering of the nation, this study proposes the new concept of “man-as-nation” to explain how the masculine virtues of male protagonists in Chinese films signify the nation’s rejuvenation and strength. Framing male virtue into the paradigms of wu (武), as martial valor, and wen (文), as cultural attainment, this article argues that masculinity has come to symbolize China’s enhanced comprehensive power and to embody its ideological orientation in both global and domestic domains.


2012 ◽  
Vol 39 (4) ◽  
pp. 859-880 ◽  
Author(s):  
PETER LEE

AbstractOver the past three decades Jean Bethke Elshtain has used her critique and application of just war as a means of engaging with multiple overlapping aspects of identity. Though Elshtain ostensibly writes about war and the justice, or lack of justice, therein, she also uses just war a site of analysis within which different strands of subjectivity are investigated and articulated as part of her broader political theory. This article explores the proposition that Elshtain's most important contribution to the just war tradition is not be found in her provision of codes or her analysis of ad bellum or in bello criteria, conformity to which adjudges war or military intervention to be just or otherwise. Rather, that she enriches just war debate because of the unique and sometimes provocative perspective she brings as political theorist and International Relations scholar who adopts, adapts, and deploys familiar but, for some, uncomfortable discursive artefacts from the history of the Christian West: suffused with her own Christian faith and theology. In so doing she continually reminds us that human lives, with all their attendant political, social, and religious complexities, should be the focus when military force is used, or even proposed, for political ends.


2020 ◽  
Vol 92 (10) ◽  
pp. 1563-1574
Author(s):  
Marie-Claire Bellissent-Funel

AbstractIn many relevant situations, water is not in its bulk form but instead attached to some substrates or filling some cavities. We shall call water in the latter environment confined water as opposed to bulk water. It is known that the confined water is essential for the stability and the function of biological macromolecules. In this paper, we provide a review of the experimental and computational advances over the past decades concerning the understanding of the structure and dynamics of water confined in aqueous solutions of biological relevance. Examples involving water in solution of organic solutes (cryoprotectants such as dimethylsulfoxide (DMSO), sugars such as trehalose) are provided.


Author(s):  
Lavanya Dalal

Trauma Studies and Prison Narratives have emerged over the past few decades as the most significant fields in the humanities. There has been a significant discussion regarding the psychological effects of incarceration; however, literature examining prison as a site of trauma is unusual. Focusing on Iftikhar Gilani's My Days in Prison (2005) and Yvonne Johnson and Rudy Wiebe's Stolen Life: The Journey of a Cree Woman (1998), the article analyzes how prison narratives represent prison as a violent space that inflicts trauma in its characters. These prison narratives represent Yvonne Johnson, the prisoner in Stolen Life, and Gilani as victims of acute psychological trauma faced due to the sheer viciousness of the prison system. The article also concentrates on how the prison experience is both similar and different in Canada and India.    


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