scholarly journals High-intensity training enhances executive function in children in a randomized, placebo-controlled trial

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
David Moreau ◽  
Ian J Kirk ◽  
Karen E Waldie
Keyword(s):  
Clinical Trial ◽  
Working Memory ◽  
Cognitive Control ◽  
High Intensity ◽  
Controlled Trial ◽  
Moderate Intensity ◽  
Promising Alternative ◽  
Trial Number ◽  
High Intensity Training ◽  
Intensity Training

Background:Exercise-induced cognitive improvements have traditionally been observed following aerobic exercise interventions; that is, sustained sessions of moderate intensity. Here, we tested the effect of a 6 week high-intensity training (HIT) regimen on measures of cognitive control and working memory in a multicenter, randomized (1:1 allocation), placebo-controlled trial.Methods:318 children aged 7-13 years were randomly assigned to a HIT or an active control group matched for enjoyment and motivation. In the primary analysis, we compared improvements on six cognitive tasks representing two cognitive constructs (N = 305). Secondary outcomes included genetic data and physiological measurements.Results:The 6-week HIT regimen resulted in improvements on measures of cognitive control [BFM = 3.38, g = 0.31 (0.09, 0.54)] and working memory [BFM = 5233.68, g = 0.54 (0.31, 0.77)], moderated by BDNF genotype, with met66 carriers showing larger gains post-exercise than val66 homozygotes.Conclusions:This study suggests a promising alternative to enhance cognition, via short and potent exercise regimens.Funding:Funded by Centre for Brain Research.Clinical trial number:NCT03255499.

Comparison of High-Intensity Training Versus Moderate-Intensity Continuous Training on Cardiorespiratory Fitness and Body Fat Percentage in Persons With Overweight or Obesity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2021 ◽  
pp. 1-14
Author(s):  
Nivash Rugbeer ◽  
Demitri Constantinou ◽  
Georgia Torres
Keyword(s):  
Body Fat ◽  
High Intensity ◽  
Mean Difference ◽  
Moderate Intensity ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Continuous Training ◽  
High Intensity Training ◽  
Significant Difference ◽  
Intensity Training

Background: High-intensity training is comprised of sprint interval training (SIT) and high-intensity interval training (HIIT). This study compared high-intensity training with moderate-intensity continuous training (MICT) on cardiorespiratory fitness (CRF) and body fat percentage for overweight or obese persons. Methods: A systematic search of randomized controlled trials using the health science databases occurred up to April, 2020. Twenty-six studies were included for complete analysis. A total of 784 participations were analyzed. The unstandardized mean difference for each outcome measurement was extracted from the studies and pooled with the random effects model. Results: MICT was significantly better at improving CRF compared with SIT (mean difference = −0.92; 95% confidence interval, −1.63 to −0.21; P = .01; I2 = 10%). Furthermore, there was no significant difference between MICT versus HIIT on CRF (mean difference = −0.52; 95% confidence interval, −1.18 to 0.13; P = .12; I2 = 23%). There was no significant difference in body fat percentage between MICT versus HIIT and MICT versus SIT. Conclusions: MICT was significantly better at improving CRF than SIT in overweight or obese persons.

scholarly journals Effects of high-intensity training on the quality of life of cancer patients and survivors: a systematic review with meta-analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ana Myriam Lavín-Pérez ◽  
Daniel Collado-Mateo ◽  
Xián Mayo ◽  
Gary Liguori ◽  
Liam Humphreys ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cancer Patients ◽  
High Intensity ◽  
Meta Analysis ◽  
Moderate Intensity ◽  
High Intensity Training ◽  
Global Quality Of Life ◽  
Intensity Training

AbstractCancer and associated medical treatments affect patients' health-related quality of life (HRQoL) by decreasing functional dimensions of physical, social, cognitive, and emotional well-being, while increasing short and late-term symptoms. Exercise, however, is demonstrated to be a useful therapy to improve cancer patients' and survivors’ HRQoL, yet the effectiveness of high-intensity training (HIT) exercise is uncertain. This systematic review and meta-analysis aimed to analyse the effects of HIT on HRQoL dimensions in cancer patients and survivors as well as evaluate the optimal prescription of HIT. The search followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA) and examined Web of Science and PubMed (Medline) databases. Data were analysed utilizing Review Manager Software. Twenty-two articles were included in the systematic review and 17 in the meta-analysis. Results showed HIT improved global quality of life, physical functioning, role functioning, social functioning, cognitive functioning, fatigue, pain, dyspnea, and insomnia, compared to an inactive control group, yet no differences were found between HIT and low to moderate-intensity exercise interventions. Particular improvements in HRQoL were observed during cancer treatment and with a training duration of more than eight weeks, a frequency of 2 days/week, and a volume of at least 120 min/week, including 15 min or more of HIT. Our findings whilst encouraging, highlight the infancy of the extant evidence base for the role of HIT in the HRQoL of cancer patients and survivors.

High-intensity training following lung cancer surgery: a randomised controlled trial

Thorax ◽  
2014 ◽  
Vol 70 (3) ◽  
pp. 244-250 ◽  
Author(s):  
E. Edvardsen ◽  
O. H. Skjonsberg ◽  
I. Holme ◽  
L. Nordsletten ◽  
F. Borchsenius ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Randomised Controlled Trial ◽  
High Intensity ◽  
Controlled Trial ◽  
Lung Cancer Surgery ◽  
Cancer Surgery ◽  
High Intensity Training ◽  
Randomised Controlled ◽  
Intensity Training

High intensity interval training alters substrate utilization and reduces oxygen consumption in the heart

2011 ◽  
Vol 111 (5) ◽  
pp. 1235-1241 ◽  
Author(s):  
A. D. Hafstad ◽  
N. T. Boardman ◽  
J. Lund ◽  
M. Hagve ◽  
A. M. Khalid ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
High Intensity ◽  
Interval Training ◽  
Substrate Utilization ◽  
Moderate Intensity ◽  
High Intensity Interval Training ◽  
Cardiac Efficiency ◽  
High Intensity Training ◽  
High Intensity Interval ◽  
Intensity Training

Aims: although exercise training induces hypertrophy with improved contractile function, the effect of exercise on myocardial substrate metabolism and cardiac efficiency is less clear. High intensity training has been shown to produce more profound effects on cardiovascular function and aerobic capacity than isocaloric low and moderate intensity training. The aim of the present study was to explore metabolic and mechanoenergetic changes in the heart following endurance exercise training of both high and moderate intensity. Methods and Results: C57BL/6J mice were subjected to 10 wk treadmill running, either high intensity interval training (HIT) or distance-matched moderate intensity training (MIT), where HIT led to a pronounced increase in maximal oxygen uptake. Although both modes of exercise were associated with a 10% increase in heart weight-to-body weight ratio, only HIT altered cardiac substrate utilization, as revealed by a 36% increase in glucose oxidation and a concomitant reduction in fatty acid oxidation. HIT also improved cardiac efficiency by decreasing work-independent myocardial oxygen consumption. In addition, it increased cardiac maximal mitochondrial respiratory capacity. Conclusion: This study shows that high intensity training is required for induction of changes in cardiac substrate utilization and energetics, which may contribute to the superior effects of high compared with moderate intensity training in terms of increasing aerobic capacity.

Sign in / Sign up

Export Citation Format

Share Document