scholarly journals Prevalence of Asymptomatic Bacteriuria and its Antibacterial Susceptibility Pattern Among Pregnant Women Attending the Antenatal Clinic at Kanpur, India

Author(s):  
R. Sujatha
2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Şevki Çelen ◽  
Ayla Sargin Oruç ◽  
Rana Karayalçin ◽  
Sibel Saygan ◽  
Serpil Ünlü ◽  
...  

Introduction. Asymptomatic bacteriuria (ASB), occurring in 2–11% of pregnancies, is a major predisposition to the development of pyelonephritis, which is associated with obstetrical complications, such as preterm labor and low birth weight infants. The aim of this study was to determine the prevalence of ASB, the antibacterial susceptibilities of the isolated microorganisms and the associated risk factors in an outpatient clinical setting in Zekai Tahir Burak Women's Health Education and Research Hospital in Ankara, Turkey. Material and Methods. Between December 2009 and May 2010, pregnant women admitted to the antenatal outpatient clinic were included in this study. The results of a complete urine analysis, midstream urine culture and antibacterial susceptibility were evaluated. Results. Of the 2011 pregnant women included, 171 had ASB (8.5%). E. coli was the most frequently isolated microorganism (76.6%), followed by Klebsiella pneumonia (14.6%). Both microorganisms were highly sensitive to fosfomycin, sensivity being 99.2% for E. coli and 88% for Klebsiella pneumonia. Conclusions. In this certain geographical region, we found E. coli as the most common causative agent of ASB in the obstetric population and it is very sensitive to fosfomycin. We recommend fosfomycin for ASB in pregnant women due to its high sensitivity, ease of administration and safety for use in pregnancy.


2020 ◽  
Author(s):  
Duresa Abu Tusuna ◽  
Teferra Abula Orjino

Abstract Background: ASB is a common problem in pregnant women and about 40% of women with untreated asymptomatic bacteriuria during pregnancy develop pyelonephritis, which might lead to low birth weight, preterm, premature rupture of membranes and preterm labour. Therefore, this study aimed to assess the prevalence of asymptomatic bacteriuria, antimicrobial susceptibility pattern of the isolates among pregnant women attending antenatal care clinic of Assosa General Hospital, western Ethiopia.Methods: A facility-based cross sectional study was conducted from January to February 2019. Well-mixed and uncentrifuged urine specimens obtained from the pregnant women was directly inoculated on cystine lactose electrolyte deficient agar (CLED) (Oxoid, Ltd, England) media by streak plate method. Bacterial isolates were identified as per the standard bacteriological procedure using colony characteristics, gram-staining, and series of biochemical tests. Antimicrobial susceptibility test was carried out by Kirby- Bauer disk diffusion technique on Muller-Hinton agar medium and the diameter of zone of inhibition was interpreted according toClinical Laboratory Standard Institute (CLSI) guidelinesResult: The overall prevalence of ASB among pregnant women in this study was 14.85%.E. coli was the most predominant isolate (50 %,) followed by K. pneumoniae (16.7%,), S. aureus (14.3%), coagulase negative staphylococci (CONS) (11.9%), and group B streptococci (GBS) (7.1%).Gram-negative bacteria were highly resistant for tetracycline (96.4%), ampicillin .Gram-positive bacteria were 100% sensitive for ceftazidime. Conclusion: Significant bacteriuria was observed in asymptomatic pregnant women. Therefore, routine laboratory diagnosis of ASB in pregnant women and providing appropriate treatment should be needed to reduce its complications.


Author(s):  
Adebayo A. Akadri ◽  
Bamidele D. Osuolale ◽  
Tessie O. Shorunmu ◽  
Oluwaseyi I. Odelola

Aims: To establish the prevalence, determinants and the antibiotic susceptibility pattern of Group B streptococcus in pregnant women in Sagamu, Ogun State, Nigeria. Study Design: Prospective cross-sectional study Place and Duration of Study: The study was carried out at the antenatal clinic at Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria, between July 2017 and December 2017. Methodology: The study involved 184 pregnant women attending antenatal clinic. Lower vaginal and rectal swabs were collected under aseptic condition and immediately sent to the laboratory for processing. The samples were assayed for the presence of group B streptococcus using conventional methods. Information on the socio demographic characteristics and details of delivery were recorded on a data capture sheet. Results: The prevalence of Group B streptococcus was 27.7%. The odds of Group B streptococcus colonization was significantly higher among women of low parity (≤ 2) and binary logistic regression analysis showed that parity was predictive of Group B streptococcus colonization (OR 3.7; 95% CI = 1.03-13.46; P=.045). Younger women (age ≤ 30 years) and women carrying term pregnancies had a non significant trend towards higher odds of Group B streptococcus colonization [(OR= 1.22, 95% CI: 0.6-2.3, P = .54) and (OR=1.6, CI: 0.8-3.2; P = .15) respectively]. The resistance of group B streptococcus isolates to penicillin and ampicillin was 39.2% and 37.3% respectively.                           Conclusion: The group B streptococcus colonization rate in this study is high. Factors such as low parity, young maternal age and term pregnancies are associated with increased odds of colonization. The emergence of resistance to the commonly prescribed antibiotics calls for re-evaluation of the current recommendations regarding the antibiotics prophylaxis.


2017 ◽  
Vol 4 (5) ◽  
pp. 1348
Author(s):  
Manasi Patnaik ◽  
Kumudini Panigrahi ◽  
Banya Das ◽  
Basanti Pathi ◽  
Nirmala Poddar ◽  
...  

Background: Asymptomatic bacteriuria (ASB) is a relatively common condition occurring due to the morphological and physiological changes in the genitourinary tract during pregnancy. If left untreated, it may lead to acute pyelonephritis and adverse fetal and maternal outcomes. The objective was to determine prevalence, risk factors and etiological agents with susceptibility for ASB among pregnant women attending an antenatal clinic at a tertiary care hospital, Odisha, India.Methods: A prospective study with 200 pregnant women was conducted, over a period of 4 months, starting from 1st April 2017 to 31st July 2017. The mid- stream clean catch urine specimen was collected and processed in all the cases and other data were collected from the questionnaire given to them. The isolates from all the cases of ASB were identified and antimicrobial susceptibility was tested by Kirby- Bauer disc diffusion method and interpreted.Results: Prevalence of ASB in our study was 25.3%, with maximum prevalence among age group 21-30 yrs, during 3rd trimester, among multigravidae. Previous history of urinary tract infection (UTI), anaemia and diabetes have significant association with ASB. Klebsiella spp. was the predominant isolate in this study followed by Escherichia coli. Nitrofurantoin and Cefixime are safe and effective antibiotics against urinary pathogens in pregnancy.Conclusions: Undiagnosed and untreated asymptomatic bacteriuria is associated with complications during pregnancy. Hence routine screening of antenatal women for ASB during all trimesters must be considered for preventing the adverse maternal and foetal outcomes particularly with known risk factors like increasing age, multiparity and previous history of UTI.  


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