scholarly journals BURN WOUND HEALING POTENTIAL OF RUBIA CORDIFOLIA LINN ON WISTAR ALBINO RATS

2017 ◽  
Vol 5 (2) ◽  
pp. 17-20
Author(s):  
Shilji Devassy ◽  
Ravi Mundugaru ◽  
Poornima Solapure ◽  
S K Hiremath ◽  
P A Patil
Keyword(s):  
Wound Healing ◽  
Albino Rats ◽  
Burn Wound ◽  
Rubia Cordifolia ◽  
Burn Wound Healing ◽  
Wistar Albino Rats

An in vitro study on the burn wound healing activity of cotton fabrics incorporated with phytosynthesized silver nanoparticles in male Wistar albino rats

2017 ◽  
Vol 100 ◽  
pp. 187-196 ◽  
Author(s):  
Balashanmugam Pannerselvam ◽  
Mukesh Kumar Dharmalingam Jothinathan ◽  
Murugan Rajenderan ◽  
Palani Perumal ◽  
Kalaichelvan Pudupalayam Thangavelu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Silver Nanoparticles ◽  
In Vitro Study ◽  
Cotton Fabrics ◽  
Albino Rats ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Wistar Albino Rats ◽  
Wound Healing Activity

scholarly journals Evaluation of burn wound healing activity of novel fusidic acid loaded microemulsion based gel in male Wistar albino rats

2020 ◽  
Vol 28 (3) ◽  
pp. 338-348 ◽  
Author(s):  
Mehmet Evren Okur ◽  
Şule Ayla ◽  
Vildan Yozgatlı ◽  
Neşe Buket Aksu ◽  
Ayşegül Yoltaş ◽  
...  
Keyword(s):  
Wound Healing ◽  
Fusidic Acid ◽  
Albino Rats ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Microemulsion Based Gel ◽  
Wistar Albino Rats ◽  
Wound Healing Activity

scholarly journals Effects of extractum cepae, heparin, allantoin gel and silver sulfadiazine on burn wound healing: an experimental study in a rat model

2012 ◽  
Vol 57 (No. 6) ◽  
pp. 287-292 ◽  
Author(s):  
AS Durmus ◽  
M. Yaman ◽  
HN Can
Keyword(s):  
Wound Healing ◽  
Rat Model ◽  
Silver Sulfadiazine ◽  
Control Group ◽  
Albino Rats ◽  
Burn Wound ◽  
Tissue Samples ◽  
Burned Areas ◽  
Positive Effects ◽  
Burn Wound Healing

These experiments were conducted in order to compare the effects of extractum cepae, heparin, allantoin gel (CTBX) and silver sulfadiazine (SSD) cream on burn wound healing in rats. Thirty six adult, female Wistar albino rats were divided into three equal groups. A burn was made on the back of all rats. The burned areas in the first, second and third groups were covered with cold cream (control), SSD skin cream and CTBX twice a day, respectively. Seven and 14 days later, the rats were sacrificed and burned skin tissue samples were collected from the rats for histopathological examinations. Histopatological evaluations on the 7<sup>th</sup> and 14<sup>th</sup> days showed burn healing to be better in the CTBX and SSD groups with respect to the control group. The best burn wound healing was observed in the CTBX group (P &lt; 0.001). Wound healing was significantly different between the groups at days 7 and 14 (P &lt; 0.001). In conclusion, application of CTBX has significant positive effects on the healing of burn wounds in a rat model. &nbsp;

scholarly journals Effects of Nigella sativa and silver sulfadiazine on burn wound healing in rats

2010 ◽  
Vol 55 (No. 12) ◽  
pp. 619-624 ◽  
Author(s):  
I. Yaman ◽  
AS Durmus ◽  
S. Ceribasi ◽  
M. Yaman
Keyword(s):  
Wound Healing ◽  
Nigella Sativa ◽  
Silver Sulfadiazine ◽  
Control Group ◽  
Albino Rats ◽  
Burn Wound ◽  
Tissue Samples ◽  
Burned Areas ◽  
Burn Wound Healing ◽  
Cold Cream

This experiment was conducted in order to compare the effects of Nigella sativa (NS) and silver sulfadiazine (SSD) cream on healing of burn wounds in rats. Fifty four adult, male Wistar-albino rats were divided into three groups of equal numbers. A burn was generated on the backs of all the rats. The burned areas in the first, second and third groups were covered with daily cold cream (control), SSD cream and NS cream (50% NS oil + 50% cold cream), respectively. Four, nine, and 14 days later, the rats were sacrificed and the burned skin tissue samples were collected for histopathological examinations. Histopatological evaluations on the 4th, 9th and 14th days showed burn healing to be better in the NS and SSD groups with respect to the control group. Wound healing was significantly different among the groups at 4th, 9th and 14th days (P &lt; 0.001). In conclusion, application of NS and SSD cream are effective in healing burn related skin wounds in the rat model.

Wound Healing Potential of Polyherbal Formulation in Rats

2021 ◽  
pp. 2195-2199
Author(s):  
Rohit Kumar ◽  
Reena Gupta ◽  
Bimlesh Kumar ◽  
Bhupinder Kapoor
Keyword(s):  
Wound Healing ◽  
Wound Care ◽  
Albino Rats ◽  
Wound Infections ◽  
Burn Wound ◽  
Polyherbal Formulation ◽  
Medicinal Plant Extracts ◽  
Healing Property ◽  
Wistar Albino Rats ◽  
Conventional Antibiotics

Chronic wound infections are significant medical burden as the patients have to go through severe discomfort and distress. Invasion of various pathogenic microorganisms at the injured site further leads to damage of tissue which may results in resection of the organ. Appropriate wound healing is necessary to regain the functional and anatomical status of the damaged tissue that got disturbed due to wound. Conventional antibiotics used for the treatment of infections are associated with various drawbacks such as high cost and high incidence of resistance. Moreover, the dressing used for wounds are also unable to provide adequate moisture to the injured tissue. All these factors emphasise on the development of new advanced technologies for wound care. Polyherbal formulations, which comprise of various medicinal plant extracts, exhibit antioxidant and anti-inflammatory properties and can be much better alternative to commercial antibiotics for treatment of wound infections. In the present study, wound healing potential of “Septaheal” (a Polyherbal formulation) was evaluated in Wistar albino rats using incision, excision and burn wound models. The formulation exhibited wound healing property due to its angiogenic and mitogenic potential.

scholarly journals Wound healing prospective of pongamia glabra, piper nigrum and momordica charantia on albino rats using anemic burn wound model

2018 ◽  
Vol 8 (6-s) ◽  
pp. 146-154 ◽  
Author(s):  
Rashmi Shukla ◽  
Varsha Kashaw
Keyword(s):  
Wound Healing ◽  
Soxhlet Extraction ◽  
Momordica Charantia ◽  
Piper Nigrum ◽  
Albino Rats ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Wound Model ◽  
Pongamia Glabra ◽  
Ointment Formulation

Objective: The objective of present work was to evaluate wound healing potential of pongamia glabra, piper nigrum and momordica charantia using as herbal ointment formulation on albino rats using burn wound model.  All the plant has the rich source of alkaloid, glycoside, tannins, carbohydrates, saponins, flavonoids, proteins and amino acids content and were used as anti-diabetic, anti-inflammatory, antitumor, anti-malarial and having wound healing potential. Materials and Methods: Extract of all three plants has been separated by the Soxhlet extraction. Herbal ointment formulation has been prepared by mixing the extract of momordica charantia, pongamia glabra and piper nigrum with the wool fat and paraffin. Burn wound model has been utilized for the evaluation of wound healing potential. Histopathological evaluation has been also carried-out for the physical verification wound healing potential. Results and Conclusion: The studies on burn wound healing model reveals that all twelve groups showed decreased wound area on the time and there was no mortality observed in the course of study. Discussion: These studies have indicated that herbal ointment formulation of pongamia glabra, piper nigrum and momordica charantia has been utilized for wound healing and it is safer for topical application. No toxicity and mortality have been observed during the experimental tenure.  Keywords: Wound healing, momordica charantia, pongamia glabra, piper nigrum, burn wound model

scholarly journals Extraction and wound healing potential of Nerium Indicum M, Artocarpus Heterophyllus Lam, Murraya Koenigii L, Punica Granatum L on albino rats using burn wound model

2019 ◽  
Vol 9 (1-s) ◽  
pp. 337-346 ◽  
Author(s):  
Renuka Shukla ◽  
Varsha Kashaw
Keyword(s):  
Wound Healing ◽  
Punica Granatum ◽  
Albino Rats ◽  
Murraya Koenigii ◽  
Burn Wound ◽  
Artocarpus Heterophyllus ◽  
Active Constituents ◽  
Burn Wound Healing ◽  
Wound Model ◽  
Ointment Formulation

Objective: The objective of present work was to extract the active constituents and evaluate the wound healing potential of Nerium indicum, Artocarpus heterophyllus, Murraya koenigii, Punica granatum on albino rats using burn wound model. Poly-herbal ointment and gel formulation was developed and compare with the extract of all plants. These plants has shown anti-asthmatic, anti-diabetic, anti-inflammatory, anti-microbial, anti-leukemic, anti-mycobacterial, antibacterial, antioxidant, antiulcer, antiviral, anticancer, antimalarial, anti-inflammatory and wound healing properties. Materials and Methods: Solvent extraction method has been utilized for the separation of the active constituents of interest by using 70% ethanol as a solvent. Poly-herbal ointment and gel formulations has been prepared by mixing the extract of Nerium Indicum, Artocarpus heterophyllus, Murraya koenigii and Punica granatum in different ratio with the ointment base (10-15%) contains PEG and for gel formulation Carbapol-940 base (10-15%). Burn wound model of albino rats has been utilized for the assessment of wound healing potential of the plant extract as well as developed formulations. Results and Conclusion: The studies on burn wound healing model reveals that F2 poly-herbal ointment formulation show better burn wound healing potential in comparison to all other formulations, F-1 ointment formulation as well as extracts of all plants. There was no mortality observed in the tenure of study. Discussion: These data has indicated that ointment and gel poly-herbal formulation of Nerium Indicum, Artocarpus Heterophyllus, Murraya Koenigii and Punica Granatum has been utilized for wound healing purpose and it is safer for topical application. No toxicity and mortality has been observed during the experimental tenure.  Keywords: Wound healing, Nerium indicum, Murraya koenigii, Punica granatum, Artocarpus heterophyllus, burn wound model.

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