scholarly journals The Potential for Acupuncture to Attenuate Hippocampal Apoptosis

Author(s):  
Hana Marsheck ◽  
Yunsuk Koh

Aims: To evaluate the potential for acupuncture to help mediate hippocampal apoptosis. Study Design: Systematic Review. Methodology: A search was conducted through PubMed, Scopus and Web of Science using the keywords “hippocampus,” “apoptosis” and “acupuncture” and found 37 qualified articles from January 2009 to March 2019. Results: All of the qualifying studies reviewed strongly support that acupuncture decreases the incidence of hippocampal apoptosis. Conclusion: It was clear that acupuncture can positively affect hippocampal apoptosis. The most frequently suggested mechanism was decreased BAX expression and increased BCL-2 expression, often in the CA1 region of the hippocampus, although it was only seen in about 1/3 of the studies reviewed. Future studies are needed to further investigate the exact mechanism associated with acupuncture in hippocampal apoptosis.

Author(s):  
Faith Zhu ◽  
Carlos Zozaya ◽  
Qi Zhou ◽  
Charmaine De Castro ◽  
Prakesh S Shah

ObjectiveTo systematically review and meta-analyse the rate of SARS-CoV-2 genome identification and the presence of SARS-CoV-2 antibodies in breastmilk of mothers with COVID-19.DesignA systematic review of studies published between January 2019 and October 2020 without study design or language restrictions.SettingData sourced from Ovid Embase Classic+Embase, PubMed, Web of Science, Scopus, relevant bibliographies and the John Hopkins University COVID-19 database.PatientsMothers with confirmed COVID-19 and breastmilk tested for SARS-CoV-2 by RT-PCR or for anti-SARS-CoV-2 antibodies.Main outcome measuresPresence of SARS-CoV-2 genome and antibodies in breastmilk.ResultsWe included 50 articles. Twelve out of 183 women from 48 studies were positive for SARS-CoV-2 genome in their breastmilk (pooled proportion 5% (95% CI 2% to 15%; I2=48%)). Six infants (50%) of these 12 mothers tested positive for SARS-CoV-2, with one requiring respiratory support. Sixty-one out of 89 women from 10 studies had anti-SARS-CoV-2 antibody in their breastmilk (pooled proportion 83% (95% CI 32% to 98%; I2=88%)). The predominant antibody detected was IgA.ConclusionsSARS-CoV-2 genome presence in breastmilk is uncommon and is associated with mild symptoms in infants. Anti-SARS-CoV-2 antibodies may be a more common finding. Considering the low proportion of SARS-CoV-2 genome detected in breastmilk and its lower virulence, mothers with COVID-19 should be supported to breastfeed.


2021 ◽  
Vol 13 (4) ◽  
pp. 95
Author(s):  
Geneci da Silva Ribeiro Rocha ◽  
Letícia de Oliveira ◽  
Edson Talamini

Blockchain is a technology that can be applied in different sectors to solve various problems. As a complex system, agribusiness presents many possibilities to take advantage of blockchain technology. The main goal of this paper is to identify the purposes for which blockchain has been applied in the agribusiness sector, for which a PRISMA-based systematic review was carried out. The scientific literature corpus was accessed and selected from Elsevier’s Scopus and ISI of Knowledge’s Web of Science (WoS) platforms, using the PRISMA protocol procedures. Seventy-one articles were selected for analysis. Blockchain application in agribusiness is a novel topic, with the first publication dating from 2016. The technological development prevails more than blockchain applications since it has been addressed mainly in the Computer Sciences and Engineering. Blockchain applications for agribusiness management of financial, energy, logistical, environmental, agricultural, livestock, and industrial purposes have been reported in the literature. The findings suggest that blockchain brings many benefits when used in agribusiness supply chains. We concluded that the research on blockchain applications in agribusiness is only at an early stage, as many prototypes are being developed and tested in the laboratory. In the near future, blockchain will be increasingly applied across all economic sectors, including agribusiness, promoting greater reliability and agility in information with a reduced cost. Several gaps for future studies were observed, with significant value for science, industry, and society.


2020 ◽  
Vol 25 (264) ◽  
pp. 139-152
Author(s):  
Manoela Abreu ◽  
Franciele Carvalho Santos ◽  
Ana Laura Nogueira ◽  
Matheus Lima Zampieri ◽  
Dernival Bertoncello

The aim of this study was to perform a systematic review of the literature in order to investigate the effects of the Pilates Method on athletes of different sports. Methods: Researches were carried out in databases (SciELO, LILACS, PubMed, Web of Science and SCOPUS) and to evaluate the methodological quality of the studies, the PEDro scale was used. Results: Of the 87 studies found, only four were included. Meta-analyzes to assess flexibility using the Wells Bank's Sit and Reach test and a fleximeter indicated improvement after Pilates application, although there were no statistically significant differences compared to the control groups (Wells Bank's Sit and Reach test: 2 , 83 95% CI: -0.73 to 6.38, I² = 99%; Fleximeter: -0.78, 95% CI: -1.84 to 0.27, I² = 0%). Conclusion: There is evidence of benefits after Pilates intervention. Future studies with standardized protocols, according to the chosen sport, are necessary to determine how the Pilates Method can improve athletes' performance.


2020 ◽  
Vol 14 (01) ◽  
pp. 128-143 ◽  
Author(s):  
Anas Imran Arshad ◽  
Paras Ahmad ◽  
Paul M.H. Dummer ◽  
Mohammad Khursheed Alam ◽  
Jawaad Ahmed Asif ◽  
...  

Abstract Objective A systematic search was performed for the identification and analysis of the 100 most often cited articles on dental caries and to highlight the changing trends in the field of dentistry over time. Materials and Methods The search was performed without any restriction on the study design, publication year, or language using the Web of Science (WoS) group of Clarivate Analytics enabling the search through “All Databases.” Based on the citation count as available in WoS, the articles were sorted in a descending manner. Information regarding each article was then extracted, which included its authorship, counts of citation (in other databases), citation density, current citation index (2019), publication year, country of publication, journal of article, evidence level based on study design, and keywords description. Results The count of citation for each article varied in each database, that is, 175 to 2,003 in WoS, 89 to 1,981 in Scopus, and 126 to 3,492 when searched in Google Scholar. The highest number of articles (n = 10) related to dental caries were published in 2004. A total of 301 authors made valuable contributions to this field, out of which J.D. Featherstone had coauthored 6 articles. A significant negative correlation (p < 0.01) was found between the age of the article and the citation density (r =–0.545). However, a nonsignificant correlation (p = 0.952) occurred between the age of publication and the citation count (r = 0.006). Conclusion The results of this systematic review provide a critical appraisal of the context underpinning scientific developments in the field of dental caries and also highlighted trends in clinical management and research.


2020 ◽  
Vol 33 (5) ◽  
pp. 865-874
Author(s):  
Elena Guadalupe Burelo-Peregrino ◽  
Marisol Salas-Magaña ◽  
Pedro Iván Arias-Vázquez ◽  
Carlos Alfonso Tovilla-Zarate ◽  
Deysi Yadira Bermudez-Ocaña ◽  
...  

BACKGROUND: Up to now there is not enough evidence that supports the use of electrotherapy in the treatment of Bell’s palsy. OBJECTIVE: Through a systematic review, we aimed to verify whether the use of electrotherapy is effective for treating Bell’s palsy or peripheral paralysis. METHODS: Publications were searched in PubMed, EBSCO and Web of Science. The present systematic review included studies that analyzed the electrotherapy as a therapeutic method for treating individuals with Bell’s palsy, in order to recover the function of facial muscles. RESULTS: Seven studies involving a total of 131 cases and 113 controls were included in this systematic review. In the studies analyzed, patients received electrotherapy combined with other treatments such as hot-wet facial napkins, massages and muscle reeducation. Although the effect of electrotherapy alone was not evaluated, the use of electrotherapy combined with other treatments produced a significant improvement in the individuals evaluated. CONCLUSIONS: Due to the diverse methodologies used and the small number of individuals included in the studies, we could not fully prove the efficacy of electrotherapy for treating Bell’s Palsy. Future studies with larger samples and homogenous populations should be performed to obtain conclusive results.


2021 ◽  
Vol 35 (4) ◽  
pp. 651-669
Author(s):  
Blanca Goni-Fuste ◽  
Iris Crespo ◽  
Cristina Monforte-Royo ◽  
Josep Porta-Sales ◽  
Albert Balaguer ◽  
...  

Background: The comprehensive assessment of needs in palliative care identifies where patients most want attention to guide clinical decisions that tailor care provision from their first encounters. Aim: To define how and what needs are identified by the comprehensive assessment of needs in the original peer-reviewed articles in the field of palliative care. Design: An integrative systematic review as outlined by Whittemore and Knafl. Quality appraisal performed using the Mixed Methods Appraisal Tool. Data sources: PubMed, CINAHL, PsycINFO, Web of Science databases searched through May 2019 and updated in July 2020. Results: Forty-nine articles met inclusion criteria for original articles in English or Spanish reporting comprehensive assessment of needs of adult patients receiving palliative care. The majority (41/49) of studies were moderate to high quality. Two themes were identified: (1) How a comprehensive assessment of needs should be carried out in palliative care, which reflected a preference to develop structured tools for assessment; (2) What needs of patients should be assessed in the comprehensive assessment of needs in palliative care, which conveyed a trend to assess beyond core domains – physical, psychological, social, spiritual – with information and practical most prevalent, but with substantial variation in specifying and classifying needs into domains. Conclusions: The assessment of needs in palliative care is comprehensive but lacks consensus on the needs and domains that should be assessed by the palliative care team. Future studies should better define what needs can be standardized into the assessment to improve process of care and patient satisfaction.


2021 ◽  
Author(s):  
Zhenjian Xu ◽  
Ying Tang ◽  
Qiuyan Huang ◽  
Sha Fu ◽  
Xiaomei Li ◽  
...  

Abstract Background: Acute kidney injury (AKI) occurs among patients with coronavirus disease-19 (COVID-19) and has also been indicated to be associated with in-hospital mortality. Remdesivir has been authorized for the treatment of COVID-19. We conducted a systematic review to evaluate the incidence of AKI in hospitalized COVID-19 patients. The incidence of AKI in different subgroups was also investigated.Methods: A thorough search was performed to find relevant studies in PubMed, Web of Science, medRxiv and EMBASE from 1 Jan 2020 until 1 June 2020. The systematic review was performed using the meta package in R (4.0.1).Results: A total of 16199 COVID-19 patients were included in our systematic review. The pooled estimated incidence of AKI in all hospitalized COVID-19 patients was 10.0% (95% CI: 7.0-12.0%). The pooled estimated proportion of COVID-19 patients who needed continuous renal replacement therapy (CRRT) was 4% (95% CI: 3-6%). According to our subgroup analysis, the incidence of AKI could be associated with age, disease severity and ethnicity. The incidence of AKI in hospitalized COVID-19 patients being treated with remdesivir was 7% (95% CI: 3-13%) in a total of 5 studies. Conclusion: We found that AKI was not rare in hospitalized COVID-19 patients. The incidence of AKI could be associated with age, disease severity and ethnicity. Remdesivir probably did not induce AKI in COVID-19 patients. Our systematic review provides evidence that AKI might be closely associated with SARS-CoV-2 infection, which should be investigated in future studies.


2020 ◽  
Author(s):  
Zhenjian Xu ◽  
Ying Tang ◽  
Qiuyan Huang ◽  
Sha Fu ◽  
Xiaomei Li ◽  
...  

Abstract Background: Acute kidney injury (AKI) occurs among patients with Coronavirus disease-19 (COVID-19) and has also been proven to be associated with in-hospital mortality. Remdesivir has been authorized for the treatment of COVID-19 patients. We conducted a systematic review to evaluate the incidence of AKI in hospitalized COVID-19 patients. The incidence of AKI in different subgroups was also investigated. Method: A thorough search was carried out to find relevant studies in PubMed, Web of Science, medRxiv and EMBASE from 1 Jan 2020 until 1 June 2020. All systemic reviews of proportions were performed using the meta package for R project (4.0.1).Results: A total of 16199 COVID-19 patients were included in our systematic review. The pooled estimated incidence of AKI in all hospitalized COVID-19 patients was 10.0% (95% CI: 7.0-12.0%). The pooled estimated need for continuous renal replacement therapy (CRRT) in COVID-19 patients was 4% (95% CI: 3-6%). According to our subgroup analysis, the incidence of AKI could be associated with the age, disease severity and the ethnicity of the patients. The incidence of AKI in hospitalized COVID-19 patients being treated with remdesivir was 7% (95% CI: 3-13%) in a total of 5 studies.Conclusion: We found that AKI was not rare in hospitalized COVID-19 patients. The incidence of AKI could be associated with age, disease severity and ethnicity. Remdesivir probably not induced AKI in COVID-19 patients. Our systemic review provides evidence for future studies that AKI might be closely associated with SARS-CoV-2 infection.


2018 ◽  
Vol 4 (2) ◽  
pp. 111-122 ◽  
Author(s):  
Ana Claudia Dias ◽  
Augusto Cunha Reis ◽  
Renata Pereira Oliveira ◽  
Úrsula Maruyama ◽  
Paloma Martinez

The healthcare environment aims at improving and quality in health management, with trends and practices in hospitals, institutions, clinics, laboratories and companies in this segment, with the purpose of bringing more comfort and better conditions in the care of patients. Faced with the difficulties of this area, it becomes increasingly important to reduce waste and improve processes. The goal of this paper is to carry out a systematic review of literature on the topic lean manufacturing in healthcare. The data were obtained from four online databases Web of Science, Science Direct, Emerald Insight and Scopus. Articles indexed in the last 10 years were selected (2006-2016). To select articles, an advanced search was performed using the Boolean expression "E" that combined keywords for better specific results. Professionals working in the health segment will have the concepts and applied techniques, in addition to the work indexed in recent years, which will facilitate the research and development of the work, translating into increased efficiency and ultimately, improvement for the population. Despite the importance of the theme, there are few lean manufacturing jobs applied in the healthcare environment. This research  can  stimulate future studies due to its applicability for the improvement of health services.  


2020 ◽  
Vol 27 (4) ◽  
Author(s):  
José Jaconias da Silva ◽  
Claudia Brito Silva Cirani

Abstract: The capability of organizational innovation is an important factor for the company to achieve a higher competitive performance. Understanding how innovation capability emerges, develops, and applies could bring important managerial and scientific contributions. This study investigates the main research results regarding the capability of organizational innovation, indicating some theoretical propositions for future studies, based on the systematic review of the literature. The research aimed to identify the determinants of organizational innovation capability and the context in which the studies are carried out. We conducted a systematic literature review based on the Web of Science database. We identified and analyzed 33 papers through the analysis of content. This study presents several research results regarding the capability of innovation in organizations, divided into internal, external and determinant aspects of innovation capability, as well as the collection of propositions for guiding a research project in depth in questions to be tested in future research. The study also brings practical contributions, as it shows in which context each study on determinants of identified innovation capability is applied, and points out the importance of innovation capability in small companies and in countries.


Sign in / Sign up

Export Citation Format

Share Document