Serum Creatinine, Urea and Their CD4+ T-lymphocyte Count among HIV Positive Patients before and after Initiation of HAART at St. Paul’s General Specialized Hospital In Addis Ababa, Ethiopia

2016 ◽  
Vol 14 (10) ◽  
pp. 1-9
Author(s):  
Mohammed Mehdi ◽  
Fisseha Bonja ◽  
Meron Yohannes ◽  
Mistire Wolde ◽  
Fatuma Hassen ◽  
...  
Keyword(s):  
Serum Creatinine ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Addis Ababa ◽  
Hiv Positive ◽  
Specialized Hospital ◽  
Before And After

scholarly journals Assessment of HIV disease progression before and after initiation of anti­retroviral therapy by CD4 & CD8 T-lymphocyte count and viral load assay

2016 ◽  
Vol 6 (1) ◽  
pp. 48
Author(s):  
Sahina Tabassum ◽  
S.M. Rashed-ul Islam ◽  
Afzalun Nessa ◽  
Munira Jahan ◽  
Saif Ullah Munshi
Keyword(s):  
Viral Load ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Published Data ◽  
Art Initiation ◽  
Cd8 T Lymphocyte ◽  
Virological Outcome ◽  
Before And After ◽  
Study Population ◽  
The Mean

<p><strong>Backgrounds:</strong> As there is no published data regarding the response to Anti-retroviral therapy (ART) among HIV patients from Bangladesh. The present study was designed to determine the immunological and virological responses of HIV infected Bangladeshi adults starting ART. Objectives: To monitor the changes of CD4 and CD8 T-lymphocyte count and Viral load (VL) before and after three and six months of starting ART.</p><p><strong>Methods:</strong> 20 symptomatic HIV infected patients with CD4 T-lymphocyte count of &lt;350 cells/µ] of blood were initiated ART.CD4 and CDS T-lymphocyte counts were estimated by Flowcytometer and VL was dete1mined by real-time PCR technique.</p><p><strong>Results:</strong> The mean CD4 T-lymphocyte count among the sn1dy patients were 177±127 cells/µl before initiation of ART. After ART initiation, their mean CD4 count increased significantly to 368±181 and 452±183 cellshll after three and six months respectively (P&lt;0.0001).The mean CDS T-lymphocyte counts were 901±650 cells/µ! before initiation of ART, which increased to I 085±393 and 1121±372 cells/µl after three and six months respectively after ART initiation (P&gt;0.05). Before ART initiation, the mean VL was 5.25±1.19 log10 (copies/ml) among the study population which became undetectable in 15 (75%) patients after three months of ART and in another 2 (10%) patients after 6 months of ART initiation.</p><p><strong>Conclusion:</strong> Our study concluded that, ART is effective in slowing the progression of HIV infection to AIDS with good immunological and virological outcome among the ART initiators.</p>

scholarly journals Prevalence of Smear-Positive Tuberculosis among Patients Who Visited Saint Paul’s Specialized Hospital in Addis Ababa, Ethiopia

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Dinna Abera Nugussie ◽  
Getachew Ali Mohammed ◽  
Anteneh Tesfaye Tefera
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Addis Ababa ◽  
Age Groups ◽  
Hiv Positive ◽  
Age Group ◽  
Hiv Status ◽  
Specialized Hospital ◽  
Urban And Rural Areas ◽  
Hiv Negative

Background. Tuberculosis (TB) continues to be a health problem in both developed and developing countries, including Ethiopia. Objective. In this study, the prevalence of smear-positive tuberculosis among presumptive TB cases who visited the hospital was assessed. Method. Acid fast bacilli (AFB) test was performed on samples collected from 200 presumptive TB cases. Data were analyzed using appropriate statistical tools. Result. Among 200 presumptive TB cases, 10% (20 individuals) (60% were male and 40% were female) were found to be positive for the AFB. Of these AFB positive subjects, 11.2% and 6.3% were from urban and rural areas, respectively. Among 20 AFB positive cases, 45% (9), 45% (9), and 10% (2) were HIV positive, HIV negative, and with HIV status unknown, respectively. The highest AFB positive cases were found within age group between 25 and 44 years (70%) and followed by age above 40 years (30%). It was found out that 75% (15), 15% (3), 5% (1), and 5% (1) were unemployed, government employed, student, and nongovernment employed, accordingly. Conclusion. This study indicated higher level of AFB positive cases within age groups of 25–44 and 65–74 years and also exhibited higher prevalence of TB cases from urban areas.

scholarly journals CD4-T LYMPHOCYTE IN CERVICAL CANCER PATIENTS ON PRE- AND POST CHEMOTHERAPY

2019 ◽  
Vol 26 (1) ◽  
pp. 30
Author(s):  
Endah Indriastuti ◽  
Endang Retnowati ◽  
Wita Saraswati
Keyword(s):  
Cervical Cancer ◽  
Cancer Patients ◽  
T Lymphocyte ◽  
Lymphocyte Count ◽  
Stage Iiib ◽  
The Third ◽  
Chemotherapy Administration ◽  
Significant Difference ◽  
Before And After ◽  
To Receive

Introduction : Cervical cancer is a gynecology cancer with the highest incidence in the Dr.Soetomo Hospital, Surabaya. Neoadjuvant chemotherapy with cisplatin has been used to increase radiosensitivy of cancer cells before radiotherapy done in advanced stage cervical cancer patients. This research aimed to know the differences of CD4-T lymphocyte profile in stage IIIB patient before and after chemotheraphy administration.Methods : This research was done in February-September 2018. Seventeen patients out of 31 stage IIIB cervical cancer patients planned to receive neoadjuvan chemotherapy with cisplatin every 3 weeks for 3 series were checked for the CD4+ T lymphocyte count and percentage. The examinations were done before the first and after the third chemotherapy administration.Results : Mean±SD of the CD4-T lymphocyte count before chemotherapy was 817±314 cells/μL and mean±SD of the CD4-T lymphocyte  percentage was 38.96±8.47%. While mean±SD of the CD4-T lymphocyte count after chemotherapy was 881±335 cells/μL and mean±SD of the CD4-T lymphocyte percentage was 39.01±8.50%. There was no significant  difference of CD4-T lymphocyte count between before and after chemotherapy (p=0.471). There was also no significant difference of CD4-T lymphocyte percentage between before and after chemotherapy (p=0.866). Both the CD4-T lymphocyte count and percentage tended to increase in postchemotherapy condition.Conclusion : The CD4-T lymphocyte count and percentage were not significantly different between before and after chemotherapy administration in stage IIIB cervical cancer patients. Both the CD4-T lymphocyte count and percentage tended to increase in postchemotherapy condition.

The Lack of Antiplatelet Effect of Crude Extracts from Ganoderma Lucidum on HIV-Positive Hemophiliacs

1990 ◽  
Vol 18 (03n04) ◽  
pp. 175-179 ◽  
Author(s):  
Jyh-Pyhg Gau ◽  
Chung-King Lin ◽  
Shiuh-Sheng Lee ◽  
Soo-Ray Wang
Keyword(s):  
T Lymphocyte ◽  
Ganoderma Lucidum ◽  
Immune Status ◽  
Hemophilia A ◽  
Hiv Positive ◽  
Antiplatelet Effect ◽  
Crude Extracts ◽  
Before And After ◽  
Suppressor T Lymphocyte

Effects of the extracts from Ganoderm lucidum (GL-P) to influence immune status of the hemophiliacs with positive HIV antibody and reversed helper/suppressor T-lymphocyte ratio were studied. Since the extracts from G. lucidum have been reported to contain high levels of adenosine, the untoward antiplatelet effect of the extracts on hemophiliacs were highly concerned. Five patients of hemophilia A voluntarily received the extracts which has been analyzed to contain 150 mg of adenosine in 100 gm of the extracts. Patients were estimated to take 1.35 mg of the adenosine daily. Platelet aggregation tests before and after the trial of the extracts showed no significant change. Our crude extracts of the Ganoderma lucidum was considered not to have untoward antiplatelet effect in vivo despite the high contents of adenosine.

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