scholarly journals Factors Favoring Non-compliance of Treatment to People Living with HIV/AIDS in General Reference Hospital of Gbadolite, Nord Ubangi, Democratic Republic of the Congo

2020 ◽  
pp. 9-24
Author(s):  
Kohowe Pagerezo Seraphin ◽  
Gédéon Ngiala Bongo ◽  
Kumbali Ngambika Guy ◽  
Koto-te-Nyiwa Ngbolua
Keyword(s):  
Marital Status ◽  
People Living With Hiv ◽  
General Reference ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Level ◽  
Risk Of Death ◽  
Reference Hospital ◽  
Level Of Knowledge ◽  
Lack Of Knowledge

Background: ART is one of the important pillars of the fight against AIDS. It restores immunity and reduces the risk of death. Its success lies in its strict compliance while its non-compliance exposes to the risk of resistance and therapeutic failure. The objective of this study was to determine the factors associated with the non-compliance to ART of PLWHA monitored at the General Reference Hospital of Gbadolite. Methodology: It was an analytical cross-sectional study conducted between December 2017 and January 2018. The compliance was measured from patient reports and by counting the number of tablets remaining from the current month of the survey. Any PLWHA who failed to take their medication at most 2 times during the month preceding the survey or whose number of remaining tablets was greater than the expected number based on the month's consumption was considered non-compliant. In total, 208 participants were selected based on the established selection criteria and several factors which led to the non-compliance of the treatment. Chi-square and logistic regression were used to determine the associations between factors and the non-compliance. All tests were performed at the threshold of ɑ=0.05. Results: In fact, 280 PLWHA had participated in the survey. The mean age was 38.7± 7.2 years while the prevalence was 51.1%. Following gender, female accounted as non-compliant (65.7%) than male The main reasons for the non-compliance to treatment were as follows: the order of frequency, medication breakdown, lack of food, forgetting, side effects, travel and fasting. Factors associated with the non-compliance were loneliness in marital status (p=0.000; OR=18.6, CI (8.926 - 38.574)), revival church religion (p=0.002; OR=9.2; CI (2.245 - 37.449)), low level of knowledge of ART principles (p=0.005; OR=1.4; CI (1.169 - 2.735)) and lack of knowledge of ART duration (p=0.021; OR=1.7 and CI (1.020 - 2.829)). Conclusion: The objective of this study was to determine the factors associated with the non-compliance of ART. The factors found in this work were those that had been found at different levels of association by many authors in previous work, namely marital status, religion, low level of knowledge about ART and lack of knowledge of duration of ART.

scholarly journals Prevalence and socioeconomic factors associated with smoking in people living with HIV by sex, in Recife, Brazil

2013 ◽  
Vol 16 (2) ◽  
pp. 432-443 ◽  
Author(s):  
Joanna d’Arc Lyra Batista ◽  
Maria de Fátima Pessoa Militão de Albuquerque ◽  
Ricardo Arraes de Alencar Ximenes ◽  
Demócrito de Barros Miranda-Filho ◽  
Heloisa Ramos Lacerda de Melo ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Socioeconomic Factors ◽  
Low Income ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Heavy Alcohol ◽  
Factors Associated ◽  
Risk Of Death ◽  
Living With Hiv ◽  
Hiv Aids

Introduction: Smoking is the leading cause of preventable death in the world. The prevalence of smoking is higher in people infected with HIV than in the general population. Although it is biologically plausible that smoking increases the morbidity and mortality of people living with HIV/AIDS, few studies in developing countries have analyzed the determinants and consequences of smoking in HIV infected people. Objective: To estimate the prevalence of smoking and identify the socioeconomic factors associated with smoking and smoking cessation in patients with HIV by sex. Methods: A cross-sectional study was conducted with baseline data, obtained from an ongoing prospective cohort study of patients with HIV attending two referral centers in Recife, Northeast Region of Brazil, between July 2007 and October 2009. Results: The prevalence of current smoking was 28.9%. For both sexes, smoking was independently associated with heavy alcohol drinking and marijuana use. Among women, smoking was associated with living alone, not being married and illiteracy; and among men, being 40 years or older, low income and using crack. Compared with ex-smokers, current smokers were younger and more likely to be unmarried, heavy drinkers and marijuana users. Conclusions: It is important to incorporate smoking cessation interventions for the treatment of heavy alcohol drinkers and marijuana users with HIV/AIDS, which may increase life expectancy and quality of life, as smoking is related to risk of death, relapse of tuberculosis, and non communicable diseases.

Anorectal pathology amongst HIV infected patients attending the Douala General Hospital: a cross-sectional study

2016 ◽  
Vol 28 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Henry Namme Luma ◽  
Servais Albert Fiacre Bagnaka Eloumou ◽  
Ellis Atemlefeh Fualefeh-Morfaw ◽  
Agnes Malongue ◽  
Elvis Temfack ◽  
...  
Keyword(s):  
Logistic Regression ◽  
General Hospital ◽  
Laboratory Data ◽  
Study Participant ◽  
Cross Sectional Study ◽  
Interquartile Range ◽  
People Living With Hiv ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

While gastrointestinal disease is common among HIV infected individuals, the prevalence and distribution of ano-rectal pathology has not been well studied in our setting. The objective of this study therefore was to determine the prevalence and determinants of ano-rectal pathology in HIV infected patients attending the Douala General Hospital HIV treatment centre. A hospital-based cross-sectional study was undertaken. We collected socio-demographic, clinical and laboratory data using a structured questionnaire and patients’ files. Each study participant had a full physical and ano-rectal examination. We further studied factors associated with having at least one ano-rectal lesion by logistic regression reporting odds ratios (ORs) and their 95% confidence intervals (CI). We included 390 HIV infected patients. The mean age was 41 (SD: 8) years and 48% were men. Median duration since HIV diagnosis was 3 (interquartile range: 2–5) years and median CD4 cell count was 411 (interquartile range: 234–601) cells/mm3. Prevalence of ano-rectal pathology was 22.8% (95% CI: 18.7–27.3). Hemorrhoids and proctitis were most common lesions found; each in 10% of patients. From multivariate logistic regression, factors associated with ano-rectal pathology were CD4 < 350 cells/ml (OR: 2.1, 95% CI: 1.1–4.2), not on highly active antiretroviral therapy (OR: 2.2, 95% CI: 1.1–4.6), inpatient (OR: 2.3, 95% CI: 1.2–4.3), ano-rectal intercourse (OR: 5.0, 95% CI: 1.7–15.1), and more than one sexual partner (OR: 2.4, 95% CI: 1.3–4.2). Ano-rectal pathology is common amongst HIV infected patients. Care givers should actively investigate and treat them as this will improve the quality of life of people living with HIV/AIDS.

scholarly journals Risk factors associated with the severity of COVID-19 in a region of the Brazilian Amazon

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Daniele Melo Sardinha ◽  
Rosane do Socorro Pompeu de Loiola ◽  
Ana Lúcia da Silva Ferreira ◽  
Carmem Aliandra Freire de Sá ◽  
Yan Corrêa Rodrigues ◽  
...  
Keyword(s):  
Risk Factors ◽  
Brazilian Amazon ◽  
The State ◽  
Metropolitan Region ◽  
Epidemiological Surveillance ◽  
Cross Sectional ◽  
Factors Associated ◽  
Risk Of Death ◽  
Increased Risk ◽  
Brazilian Amazon Region

AbstractThe Brazilian Northern region registered a high incidence of COVID-19 cases, particularly in the state of Pará. The present study investigated the risk factors associated with the severity of COVID-19 in a Brazilian Amazon region of 100,819 cases. An epidemiological, cross-sectional, analytical and demographic study, analyzing data on confirmed cases for COVID-19 available at the Brazilian Ministry of Health's surveillance platform, was conducted. Variables such as, municipalities of residence, age, gender, signs and symptoms, comorbidities were included and associated with COVID-19 cases and outcomes. The spatial distribution was performed using the ArcGIS program. A total of 100,819 cases were evaluated. Overall, patients had the mean age of 42.3 years, were female (51.2%) and with lethality reaching 4.79% of cases. Main symptoms included fever (66.5%), cough (61.9%) and sore throat (39.8%). Regarding comorbidities, most of the patients presented cardiovascular disease (5.1%) and diabetes (4.2%). Neurological disease increased risk of death by nearly 15 times, followed by obesity (5.16 times) and immunodeficiency (5.09 time). The municipalities with the highest incidence rate were Parauapebas, Canaã dos Carajás and Jacareacanga. Similarity between the Lower Amazon, Marajó and Southwest mesoregions of Pará state were observed concerning the highest morbidity rates. The obtained data demonstrated that the majority of cases occurred among young adults, females, with the classic influenza symptoms and chronic diseases. Finally, data suggest that the highest incidences were no longer in the metropolitan region of the state. The higher lethality rate than in Brazil may be associated with the greater impacts of the disease in this Amazonian population, or factors associated with fragile epidemiological surveillance in the notification of cases of cure.

scholarly journals Demographic Features of Identified PLWHA Infected through Commercial and Nonmarital Noncommercial Heterosexual Contact in China from 2015 – 2018: A Retrospective Cross-Sectional Study

2020 ◽  
Author(s):  
Zhilong Dong ◽  
Liying Ma ◽  
Chang Cai ◽  
George Fu Gao ◽  
Fan Lyu
Keyword(s):  
Marital Status ◽  
Educational Level ◽  
Hiv Transmission ◽  
Cross Sectional Study ◽  
Demographic Characteristics ◽  
Heterosexual Transmission ◽  
People Living With Hiv ◽  
Heterosexual Contact ◽  
Cross Sectional ◽  
Hiv Aids

Abstract Background:Understanding the demographic characteristics of people living with HIV/AIDS (PLWHA) infected through commercial heterosexual contact (CHC) or nonmarital noncommercial heterosexual contact (NMNCHC) is important for HIV/AIDS prevention and control.Methods:Cases reported through the Chinese HIV/AIDS Case Reporting System (CRS) from 2015 to 2018 were analyzed. A descriptive and preliminary inferential analysis were performed for those demographic characteristics deemed of interest.Results:Overall, 523,121 identified PLWHA between 2015 and 2018 in the CRS were analyzed. The constituent ratio of heterosexual transmission increased from 66.25% in 2015 to 71.48% in 2018. The proportion of CHC heterosexual transmission decreased from 40.18% in 2015 to 37.99% in 2018, while that of NMNCHC increased from 46.33% in 2015 to 49.02% in 2018. PLWHA infected through NMNCHC were significantly younger than those who were infected through CHC (Student’s t test, P<0.0001), with an average age gap ranging from 5.63 (2015) to 7.46 (2018) years, and the average age of both groups increased annually. The frequency of newly identified PLWHA who were infected through CHC had a remarkable increase among the ages of 65 and above. Gender distribution was significantly different between CHC and NMNCHC (χ2 = 8909.00(2015), 9941.90(2016), 11004.00 (2017), 12836.00(2018), all P < 0.0001), and the ratio of men to women in the NMCHC group was 1.50:1 (2015), 1.51:1 (2016), 1.54:1 (2017), and 1.52:1 (2018), while in the commercial heterosexual contact (CHC) group, these ratios were 11.45:1 (2015), 12.08:1 (2016), 12.53:1 (2017), and 13.28:1 (2018). Marital status was significantly different between CHC and NMNCHC (χ2 = 94.67 (2015), 109.88(2016), 58.18(2017), 152.38(2018), all P < 0.0001). As the educational level improved, the proportion of NMNCHC also increased (Cochran - Armitage test, P<0.0001).Conclusions:We found that heterosexual transmission was the primary mode of HIV transmission in China from 2015 to 2018. PLWHA infected through CHC and NMNCHC had different characteristics in age, gender, marital status, and educational level. The frequency of PLWHA infected through CHC increased substantially in the age group of 65 and above. This study provides useful baseline data for future studies on the heterosexual transmission of HIV in China.

scholarly journals Factors Associated with Anemia among People Living with HIV/AIDS Taking ART in Ethiopia

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Ketema Bizuwork Gebremedhin ◽  
Tadesse Bedada Haye
Keyword(s):  
Addis Ababa ◽  
Clinical Stage ◽  
Public Health Problem ◽  
People Living With Hiv ◽  
Major Public Health Problem ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Factors Associated ◽  
Living With Hiv ◽  
Hiv Aids

Background. Globally, anemia, among people living with HIV/AIDS, is a major public health problem. It has a significant effect on the progression of HIV/AIDS to advanced stages and there are a number of factors that often affect anemia. However, there is little insight regarding factors affecting anemia among HIV/AIDS patients in developing countries, including Ethiopia. Objective. This study aimed at investigating factors affecting anemia among people living with HIV/AIDS taking ART drug at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods. A hospital based cross-sectional study design was used to assess factors affecting anemia among people living with HIV/AIDS. Structured checklist was used to gather information from charts of patients selected by simple random sampling method. We analyzed the data to identify factors associated with anemia among people with HIV/AIDS using logistic regression models. Results. A total of 301 selected charts were reviewed. The median age was 38 ± 10.38. The majority (62.5%) of the patients were taking ZDV-containing ART drug (ZDV/3TC/NVP). The overall anemia prevalence was 34.6%, while about 5%, 15.6%, and 14% of the patients had severe, moderate, and mild prevalence of anemia, respectively. Factors that were found to affect anemia among these patients include gender (OR = 2.26 [95% CI: 1.22, 4.16]), occupation (OR: 0.57 [95%CI: 0.35, 0.92]), WBC count (OR = 2.30 [95% CI: 1.29, 4.09]), platelet count (OR = 2.89 [95% CI: 0.99, 8.41]), nutritional status (OR = 2.05 [95% CI: 0.69, 6.02]), and WHO clinical stage of HIV/AIDS (OR = 3.69 [95% CI: 1.86, 7.31]). Conclusions. About one in three patients was found to be anemic. Intervention aimed at diagnosing and treating anemia among people living with HIV/AIDS should be considered.

scholarly journals Prevalence and Factors Associated with Depression among HIV/AIDS-Infected Patients Attending ART Clinic at Jimma University Medical Center, Jimma, Southwest Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Beyene Dorsisa ◽  
Gutema Ahimed ◽  
Susan Anand ◽  
Tariku Bekela
Keyword(s):  
Medication Adherence ◽  
Marital Status ◽  
Opportunistic Infection ◽  
Medical Center ◽  
Bivariate Analysis ◽  
People Living With Hiv ◽  
Southwest Ethiopia ◽  
Factors Associated ◽  
Jimma University ◽  
Hiv Aids

Background. HIV is a chronic life-threatening illness and, like other similar chronic and stigmatizing illnesses, can be stressful to manage. Depression is a common mental health problem that deteriorates the quality of life of people with HIV/AIDS and found to be a strong predictor for noncompliance to antiretroviral therapy treatment. Therefore, epidemiological evidence on the factors associated with depression among patients with HIV/AIDS can contribute towards effective and efficient preventive health care strategies for this population. Objectives. To assess the prevalence and factors associated with depression among HIV/AIDS-infected patients attending ART clinic at Jimma University Medical Center, Jimma, Southwest Ethiopia, in 2018. Methods. This study followed an institution-based cross-sectional quantitative study design. A simple random sampling method yielded 303 participants who were interviewed from April to May 2018, using a pretested questionnaire, followed by their card review. The SPSS version 23 was used for bivariate analysis which was used to find out the significance of association. Variables that showed association in bivariate analysis at p value < 0.25 were entered to multivariable logistic regressions to control for confounders, and the significance of association was determined by 95% confidence interval and p value < 0.05. Results. The point prevalence of depression was 94 (31%). Variables like sex (AOR=0.510 (95%CI=0.264‐0.986)), marital status (AOR=3.610 (95%CI=1.649‐7.901)), opportunistic infection (AOR=3.122 (95%CI=1.700‐5.733)), and medication adherence (AOR=0.470 (95%CI=0.266‐0.831)) were significantly associated with depression. Conclusion and Recommendation. From the findings of this study, it is possible to conclude that depression was highly prevalent among people living with HIV/ADS. Sex, marital status, opportunistic infection, and medication adherence were found to be associated with depression and need attention from the health professional working in the ART clinic.

scholarly journals Psychological hardiness and its relationship to health awareness Among Kurdish people in Kurdistan Region during the pandemic of Covid-19.

2021 ◽  
pp. 29-36
Author(s):  
Trifa Murad Mohammed ◽  
Hanaw Hasan Mohammedhkan ◽  
Delan Jamal Qader ◽  
Fatah Hama Rahim
Keyword(s):  
Future Research ◽  
Kurdistan Region ◽  
Wide Spread ◽  
Health Awareness ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Level ◽  
Psychological Hardiness ◽  
Cross Sectional Design ◽  
Significant Factors

Objective: Like Iraq and neighboring countries, the Kurdistan region was affected by the epidemic which gradually led to a lockdown in March and April and a wide-spread disruption of people’s life and activates. In this study, the researcher investigated the psychological hardiness and its relation to health awareness among citizens of the Kurdistan region during the Corona epidemic. Methods: This study followed a cross-sectional design quantitative survey that was conducted online from 1 to 18 April 2020. After two months of lockdown due to coronavirus pandemic in the Kurdistan Region. A questionnaire of 25 questioners to measure psychological hardiness, later the researchers got the psychometric qualities. Results: The researcher observed high psychological hardiness levels in the study, because of the Covid-19 pandemic. It has shown the non-significant association between psychological hardiness and health awareness and identified several significant factors associated with this psychological hardiness and health awareness. Conclusion: Using contractive tools, the study showed that the psychological hardiness of the citizens of the Kurdistan region is at a low level during the COVID-19 pandemic. The results could serve as a framework for future research to examine the influence of the pandemic on the population's association of psychological hardiness with health awareness.          

scholarly journals Magnitude of optimal adherence and predictors for a low level of adherence among HIV/AIDS-infected adults in South Gondar zone, Northwest Ethiopia: a multifacility cross-sectional study

BMJ Open ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. e056009
Author(s):  
Shimeles Biru Zewude ◽  
Tewodros Magegnet Ajebe
Keyword(s):  
Associated Factors ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Level ◽  
South Gondar ◽  
Hiv Aids

ObjectivesThis study aims to identify levels of adherence to antiretroviral therapy (ART) drugs and factors associated with them in Northwest Ethiopia. We hypothesise that in the era of COVID-19, there would be suboptimal adherence to ART drugs.DesignAn observational cross-sectional study was conducted. Factors associated with the level of adherence were selected for multiple logistic regressions at a p value of less than 0.2 in the analysis. Statistically significant associated factors were identified at a p value less than 0.05 and adjusted OR with a 95% CI.SettingThe study was conducted in one specialised hospital and three district hospitals found in the South Gondar zone, Northwest Ethiopia.ParticipantsAbout 432 people living with HIV/AIDS receiving highly active ART in South Gondar zone public hospitals and who have been on treatment for more than a 3-month period participated in the study.Primary and secondary outcome measuresLevels of adherence to ART drugs and their associated factors.ResultsAmong 432 study participants, 81.5% (95% CI: 78% to 85.2%) of participants were optimally adherent to ART drugs. Determinants of a low level of adherence: stigma or discrimination (OR=0.4, p=0.016), missed scheduled clinical visit (OR=0.45, p=0.034), being on tuberculosis treatment (OR=0.45, p=0.01), recent CD4 cell count less than 500 cells/mm3 (OR=0.3, p=0.023) and patients who had been on WHO clinical stage III at the time of ART initiation (OR=0.24, p=0.027) were factors significantly associated with adherence to ART drugs.ConclusionsLevel of adherence was relatively low compared with some local studies. The intervention targeted to reduce discrimination, counselling before initiation of treatment and awareness regarding compliance is advised to improve adherence to antiretroviral regimens.

scholarly journals Towards Sustainable Development: Exploring the Knowledge of Environmental Impact Assessment among Undergraduates in a Nigerian University

2020 ◽  
pp. 1-10
Author(s):  
Queencallista N Sidney- Nnebue ◽  
Anita O. Garba ◽  
Gbenga E. Fadiora ◽  
Felicia C. Etim ◽  
Amanda N. Ezenagu ◽  
...  
Keyword(s):  
Environmental Impact ◽  
Marital Status ◽  
Impact Assessment ◽  
Environmental Impact Assessment ◽  
Statistical Significance ◽  
P Value ◽  
Sources Of Information ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Level Of Knowledge

Background: Efficient project management suffices that decision makers are adequately informed on the impacts of their actions and inactions on the environment. Objective: To explore the knowledge of environmental impact assessment (EIA) among undergraduates of the faculty of environmental sciences in a university in Nigeria.                                                Materials and Methods: This was a cross sectional survey of 350 undergraduates selected via multistage sampling technique. Data were obtained using self- administered semi-structured questionnaires, and analysed using statistical package for social sciences software version 22. Statistical significance were done using Chi-square test at p value < 0.05. Results: Two hundred and eighteen (62.3%) respondents reported awareness of EIA and cited their sources of information on EIA as 111(50.6%) schools, 109 (50%) textbooks, etc. Only (12.6%) out of 350 respondents had good level of knowledge on EIA. Fifty one (14.6%) out of 350 respondents reported ever participated in EIA process, while 34 (9.7%) were participating in EIA process currently. The level of knowledge of EIA process among respondents significantly vary with [gender, p=0.002) and marital status, p= 0.032)] respectively. Conclusions: This study found apparently poor awareness of EIA, poor knowledge of EIA and poor participation in the EIA process. The level of knowledge on EIA vary significantly with gender and marital status. We recommend comprehensive but targeted, need- based environmental education to help create awareness, impart knowledge and equip these students with EIA strategies and skills to handle environmental challenges.

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