scholarly journals Comparative Efficacy of 50% Trichloroacetic Acid Solution with 10% Potassium Hydroxide Solution in the Treatment of Plane Warts

2019 ◽  
pp. 1-10
Author(s):  
Reza Yaghoobi ◽  
Nader Pazyar ◽  
Bahareh Maleki
Keyword(s):  
Trichloroacetic Acid ◽  
Potassium Hydroxide ◽  
Potassium Hydroxide Solution ◽  
Complete Response ◽  
Treatment Modalities ◽  
Trichloroacetic Acid Solution ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Moderate Response

Background: Warts are very common disorders. Plane warts are caused by Human Papilloma Virus (HPV) occurring mostly in children and young adults. Among the treatment modalities, topical application of trichloroacetic acid (TCA) is age old. Potassium hydroxide (KOH) has a keratolytic effect on virus-infected cells. Aims: To compare the safety and efficacy of topical 10% KOH solution with 50% TCA solution in the treatment of plane warts. Materials and Methods: Sixty-four consecutive patients with plane warts were randomly assigned into two groups of thirty-two patients. Group A received 10% KOH solution and group B received 50% TCA solution once weekly until the complete clearance of warts in a maximum period of 12 weeks. Results: In group under treatment with 10% KOH, 24 patients (75.0%) complete response, 5 patients (15.6%) moderate response, 2 patients (6.3%) mild response, and 1 patient (3.1%) had no response. In group under treatment with 50% TCA, 28 patients (87.5%) showed complete response, 2 patients (6.3%) moderate response, 2 patients (6.3%) mild response. Statistically no significant difference was found between the therapeutic response to 10% KOH and 50% TCA (P=0.41). Conclusion: 10% KOH was found to be equally effective in the treatment of plane warts compared to 50% TCA with the advantage of fewer side effects.

A Comparative Study of Epidemiology, Clinicopathologic Features and Outcome of Colorectal Cancer Patients between Ain Shams University Hospitals and Luxor International Hospital

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Tarek Hussein Kamel ◽  
Amr Lotfy Farag ◽  
Dr/Sherif Hassanin Ahmed ◽  
Chresteen Talaat Samy Hanna
Keyword(s):  
Colorectal Cancer ◽  
Comparative Study ◽  
Disease Free Survival ◽  
University Hospital ◽  
Treatment Modalities ◽  
Clinicopathologic Features ◽  
Free Survival ◽  
Significant Difference ◽  
Group A ◽  
Group B

Abstract Background Colorectal cancer (CRC) is one of the leading causes of mortality and morbidity in the world. It is the third most common malignancy after lung & breast and the fourth leading cause of cancer-related deaths worldwide, accounting for approximately 1,400,000 new cases and about 700,000 deaths worldwide. Objectives The aim of this retrospective study is to compare the epidemiology, clinicopathologic features, different treatment modalities and outcomes regarding disease free survival (DFS), progression free survival (PFS) & overall survival (OS) of colorectal cancer disease between cases presented to Ain shams university hospital & to Luxor international hospital in 3 consecutive years. Patients and Methods The study is retrospective comparative study. Clinical oncology department in Ain Shams University Hospital and Luxor International Hospital. The data Collected from January 2013 to December 2015. This study analyzed hospital records of patients who diagnosed with colorectal cancer (CRC) and allocated into two groups: Group A: CRC patients presented to Ain-Shams University Hospital from January 2013 to December 2015, group B: CRC patients presented to Luxor International Hospital from January 2013 to December 2015. Results There was no statistically significant difference regarding age parameter in LIH when compared to ASU, but the study was consistent with higher incidence in patients who were aged more than forty- accounted about 70.5% in all CRC cases. Cases less than 40 years old, in group A were 35.2%, while in Group B were 23.5%. Even there was no statistically significant difference but it may be attributable to more westernization in Lower Egypt. Other explanation may be due to decreased low socioeconomic status and different lifestyle factors in more developing region what increase risk of colorectal cancer. Among our cases, there is no statistically significant difference regarding gender between the two hospitals. Both sexes almost were affected equally, females appeared to be at a slightly higher risk of developing CRC cancer with current prevalence 1.3:1 in ASU group, and 1.1:1 in LIH group. Conclusion The need to increase awareness about CRC in Egypt especially upper Egypt, is recommended. An awareness campaign should be performed to promote detection of CRC at its earliest and most curable stage by recognizing early symptoms and enabling early referrals for colonoscopy. Those at higher risk should be offered more intensive surveillance. Similarity of the data from different centers suggests that this is the picture of colorectal cancer typical of Egypt.

scholarly journals Comparing efficacy of Rifaximin plus Lactulose vs. Lactulose alone in treating Hepatic Encephalopathy

2020 ◽  
Vol 24 (4) ◽  
pp. 339-343
Author(s):  
Tanveer Hussain ◽  
Misbah Sattar ◽  
Sara Mustafa ◽  
Uzma Batool ◽  
Shafqat Iqbal ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Local Population ◽  
Tertiary Care ◽  
Simple Random Sampling ◽  
Complete Recovery ◽  
Treatment Modalities ◽  
Care Hospital ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Hepatic Encephalopathy is a syndrome observed in patients with liver cirrhosis. Various treatment modalities are in use for treatment of Porto Systemic Encephalopathy (PSE). Our study aimed to compare the efficacy of Rifaximin plus Lactulose vs.Lactulose alone in treating Hepatic Encephalopathy in local population. Materials & Methods: The study was conducted at a tertiary care hospital recruiting decompensated chronic liver disease(DCLD) patients with PSE. Using simple random sampling, patients were divided in two groups (A & B). Patients in group A received Lactulose plus Rifaximin while group B received Lactulose alone. Efficacy of treatment was assessed as return of the conscious level to pre-encephalopathy state as per clinical examination within 1 week after  start of the treatment. Results: A total of 124 patients were included in the study with each group (A & B) containing 62 patients. Frequency and percentage of efficacy among group A (Rifaximin plus Lactulose) verses group B (Lactulose alone) in treating Hepatic encephalopathy was 45 (72.6%) and 32 (51.6%) respectively. Conclusion: The study concluded that there is a significant difference in proportions of patients showing complete recovery from Hepatic encephalopathy treated with Lactulose plus Rifaximin as compared to Lactulose alone.

Dose-Dense Sequential Chemotherapy With Epirubicin and Paclitaxel Versus the Combination, as First-Line Chemotherapy, in Advanced Breast Cancer: A Randomized Study Conducted by the Hellenic Cooperative Oncology Group

2001 ◽  
Vol 19 (8) ◽  
pp. 2232-2239 ◽  
Author(s):  
George Fountzilas ◽  
Christos Papadimitriou ◽  
Urania Dafni ◽  
Dimitrios Bafaloukos ◽  
Dimosthenis Skarlos ◽  
...  
Keyword(s):  
Overall Response Rate ◽  
Response Rate ◽  
Complete Response Rate ◽  
Complete Response ◽  
First Line ◽  
Significant Difference ◽  
Group A ◽  
Dose Dense ◽  
Group B ◽  
Line Chemotherapy

PURPOSE: To compare the efficacy of two different schedules of epirubicin and paclitaxel, as first-line chemotherapy, in patients with advanced breast cancer (ABC). PATIENTS AND METHODS: From October 1997 until May 1999, 183 eligible patients with ABC entered the study. Chemotherapy in group A (93 patients) consisted of four cycles of epirubicin at a dose of 110 mg/m2 followed by four cycles of paclitaxel at a dose of 225 mg/m2 in a 3-hour infusion. All cycles were repeated every 2 weeks with granulocyte colony-stimulating factor support. The therapeutic regimen in group B (90 patients) consisted of epirubicin (80 mg/m2) immediately followed by paclitaxel (175 mg/m2 in a 3-hour infusion) every 3 weeks for six cycles. RESULTS: In total, 79 patients (85%) in group A and 72 patients (80%) in group B completed treatment. The median relative dose-intensity of epirubicin was 0.96 in both groups, and that of paclitaxel was 0.96 and 0.97 in groups A and B, respectively. The complete response rate was higher in group A (21.5% v 9% P = .02). Nevertheless, there was no significant difference in the overall response rate between the two groups (55% v 42%, P = .10). Severe neutropenia was more frequently observed with concurrent treatment. After a median follow-up of 16.5 months, median time to progression was 10 months in group A and 8.5 months in group B (P = .27), and median survival was 21.5 and 20 months, respectively (P = .17). CONCLUSION: The present study failed to demonstrate a significant difference in overall response rate between dose-dense sequential administration of epirubicin and paclitaxel compared with the combination of the two drugs given on the same day, even though the sequential treatment resulted in a significantly higher complete response rate.

scholarly journals Effect of Erbium:Yttrium-Aluminum-Garnet Laser Combined with Mineralizing Agents on Microhardness of Demineralized Dentin

2019 ◽  
Vol 13 (01) ◽  
pp. 011-016
Author(s):  
Hila Hajizadeh ◽  
Atefeh Nemati-Karimooy ◽  
Peiman Babaee-Rishkhori
Keyword(s):  
Er:Yag Laser ◽  
Additional Treatment ◽  
Treatment Modalities ◽  
Control Group ◽  
Significant Difference ◽  
Group A ◽  
Casein Phosphopeptide ◽  
Group B ◽  
Post Hoc ◽  
Demineralized Dentin

Abstract Objective The aim of this study was to assess the combined effect of erbium:yttrium-aluminum-garnet (Er:YAG) laser and mineralizing agents including casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride in improving the resistance of demineralized dentin at new demineralization process. Materials and Methods One hundred and twenty healthy dentin surfaces were prepared and demineralized using acidic solutions. Primary microhardness was measured (h1), and samples were randomly divided into six groups. Each group received a different protocol as follows: Group A (control group): no additional treatment, Group B: applying a fluoridated gel, Group C: applying a CPP-ACP-containing cream, Group D: irradiation of Er:YAG laser, Group E: irradiation of Er:YAG laser combined with the application of a fluoridated agent, and Group F: irradiation of Er:YAG laser combined with the application of CPP-ACP-containing cream. Microhardness values were measured afterward (h2). Then, all the groups were re-exposed to acidic solution, and microhardness was measured for the third time (h3). The microhardness data were analyzed using analysis of variance and Scheffe's post hoc test. Results Although application of mineralizing agents increased the microhardness of demineralized dentin in comparison with the control group, no significant difference was observed using two agents. Comparison of laser groups showed an increase in microhardness only after the irradiation of Er:YAG laser combined with the application of a fluoridated agent. Demineralizing process reduced the microhardness values in all the groups, but the application of a CPP-ACP agent caused the least reduction among the laser irradiated groups. Comparison of hardness changes at the beginning and end of the experiment did not show any significant differences between the groups. Conclusion Comparison of treatment modalities used in this study exhibited that fluoride had the greatest impact on dentin resistance. Laser irradiation on demineralized dentin did not increase the hardness or resistance to acidic attacks.

scholarly journals A Pilot Study to Evaluate HEMA based Desensitising Agent and 980 nm Diode Laser in Dentinal Hypersensitivity

2020 ◽  
Author(s):  
Anupama Ahirwar ◽  
Anuj Bhargava ◽  
Sanjesh Kumar Meena
Keyword(s):  
Diode Laser ◽  
Repeated Measures ◽  
Repeated Measure ◽  
Treatment Modalities ◽  
Dentinal Tubule ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
High Cervical ◽  
Dentinal Hypersensitivity

Introduction: Dentinal Hypersensitivity (DH) presents as a short, intense pain emanating from exposed dentinal tubules. Many studies have concluded that mechanical, chemical or both factors increase the frequency of DH. Sealing of exposed dentinal tubule can be achieved with the use of Dental adhesives, restorations, Desensitising Agents (DA) and Lasers, each having their own mechanism of action. Aim: This clinical study was done to evaluate the efficacy of Hydroxy Methacrylate (HEMA) based DA and 980 nm diode laser in the treatment of DH. Materials and Methods: This two-arm parallel design split-mouth study was conducted on 30 adult patients attending the Dental Outpatient Clinic of Gandhi Medical College, Bhopal during the year December 2018 to January 2020 with clinically diagnosed high cervical DH (Charlie=3) occurring bilaterally in maxillary canine teeth. Scoring of baseline and postoperative DH was done utilising using Modified U.S. Public Health Service Criteria for DH Assessment. After recording the pretreatment baseline scores, mouth of each sample subject was divided bilaterally using split-mouth technique into Group A and Group B. The left side of patient’s mouth was designated as Group A in which a 10 W Diode Laser (980 nm) was used and right side of the patient’s mouth was classified as Group B, in which Shield Active (HEMA based) DA was used. The sensitivity score for both the groups was assessed immediately after application, after 24 hours, after seven days and after 21 days. Statistical Analysis was done by using Statistical Package for Social Sciences(SPSS) software version 22.0. Student’s t-test and repeated measures of ANOVA Test were applied. The p-value of less than 0.05 was considered statistically significant. Results: There was a statistically highly significant difference in sensitivity scores between both groups immediately after treatment p=0.038, after 24 hours, seven days and after 21 days. (p<0.001) depicting high efficacy of Diode lasers over DA. Repeated Measure of ANOVA was applied to find difference in mean score from baseline to 21 days. Immediately after application the results in Group A compared to baseline were statistically highly significant (p<0.001) and statistically significant in Group B (p<0.05). However, overall difference after 21 days compared to baseline were not significant in any group (p>0.05) depicting that the effect of both the desensitising therapies were not significant beyond 21 days in both the groups. Conclusion: Within the limits of this study, it can be concluded that both HEMA based DA and 980 nm diode laser were effective desensitisation treatment modalities for achieving immediate reduction of high cervical dentin hypersensitivity from baseline. Further, 980 nm Diode laser was found to be more efficacious and effective treatment option than HEMA based DA for treatment of DH.

scholarly journals Efficacy and safety of iontophoresis combined sodium salicylate in acquired plantar keratoderma-a randomized controlled study

2021 ◽  
Vol 8 (1) ◽  
pp. 101
Author(s):  
Shreya P. Somani ◽  
Bhavsh N. Astik ◽  
Hita H. Mehta ◽  
Milan D. Jhavar
Keyword(s):  
Sodium Salicylate ◽  
Randomized Controlled Study ◽  
Treatment Modalities ◽  
Controlled Study ◽  
Mean Values ◽  
Randomized Controlled ◽  
Number Of Patients ◽  
Significant Difference ◽  
Group A ◽  
Group B

<p><strong>Background</strong>: Palmoplantar keratoderma is a heterogenous group of disorders, hereditary or acquired, characterized by thickening of palms and soles. Though it is not a life-threatening condition, it affects individual’s quality of life. As treatment of keratoderma has always been troublesome, upgraded treatment modalities which improves keratoderma efficiently are always encouraged.</p><p><strong>Methods</strong>: In this randomized controlled study, patients of plantar keratoderma of age group of 18-65 years were randomly divided in group A and group B. In group A, iontophoresis combined sodium salicylate was offered to patients twice weekly for 8 weeks of duration, during which DC current was supplied at 5-15 mA for 10 min of duration. Whereas, in group B patients applied topical salicylic acid 12% ointment at home twice a day for 8 weeks.</p><p><strong>Results</strong>: Our study of 70 patients of keratoderma, revealed diffuse (94%) pattern of involvement with female preponderance (55.7%) and occupation wise, most common among laborers (54.2%) followed by housewives (27.1%). Statistically significant number of patients showed reduction in severity grading of parameters, in both groups at end of 8 weeks. Same way, mean values of parameter grading significantly reduced at 8 weeks in both the groups. But intergroup values showed no significant difference. Mean EASI (Eczema Area Severity Index) score showed statistically significant reduction in group B as compared to group A at 8<sup>th</sup> week. Percentage of reduction of EASI score was also significantly higher in group B at end of treatment.</p><p><strong>Conclusions:</strong> Here both treatment modalities are safe and effective, topical being slightly more efficacious than iontophoresis. So, we can conclude that no additional privilege of drug delivery through iontophoresis.</p>

scholarly journals Eficacy of trichloroacetic acid peel versus 15% topical azelaic acid gel in the treatment of acne vulgaris – a comparative study

2015 ◽  
Vol 61 (1) ◽  
pp. 25-30
Author(s):  
Stela Mariana Al Hussein ◽  
F. Buicu ◽  
Dalila Maier ◽  
H. Al Hussein ◽  
Adriana Ciurba ◽  
...  
Keyword(s):  
Azelaic Acid ◽  
Trichloroacetic Acid ◽  
Acne Vulgaris ◽  
Skin Irritation ◽  
Local Skin ◽  
Contraceptive Pills ◽  
Significant Difference ◽  
Group A ◽  
Acid Gel ◽  
Group B

Abstract Objectives: The aim of this study was to compare the efficacy and tolerability of 20% trichloroacetic acid (TCA) peel with 15% azelaic acid gel, a standard antiacne topical treatment. Materials and methods: 51 patients aged between 16-40 years, with mild and moderate acne, were randomized into two groups. Before the treatment were investigated the patients clinical features and hygienic habits, the previous antiacne treatments and feed-back to them. No cases under treatment with contraceptive pills or antiacne medication that could interfere with the results, were included. For a period of eight weeks, 27 patients (group A) were treated with 15% azelaic acid gel, twice daily, and 24 patients (group B) underwent four sessions of 20% TCA peels, at 14 days interval. The efficacy was evaluated by acne lesions counting, at baseline and at 8 weeks. Adverse effects incidence (erythema, local skin irritation), as well as the satisfaction degree of patients, were investigated. Results: Was observed a mean reduction in the number of acne lesions of 32,36% for the group A and 69,36% for the group B. There was no statistically significant difference between the average number of acne lesions before treatment between the two groups. The mean number of acne lesions after the treatment was significantly different (p<0,0001), 20% TCA peels showed superior results than 15% azelaic acid gel. Additionally, 96% of patients who underwent TCA peels were very satisfied with the results obtained. Conclusions: TCA peel is an efficient and well tolerated method for the treatment of acne vulgaris.

scholarly journals SCABIES;

2012 ◽  
Vol 19 (01) ◽  
pp. 086-092
Author(s):  
MUNAZZA SAQIB ◽  
ITAAT ULLAH AFRIDI ◽  
ANSER ALI ◽  
Muhammad Jahangir
Keyword(s):  
Side Effects ◽  
Significant Rise ◽  
Limiting Factors ◽  
Treatment Modalities ◽  
Hepatic Enzymes ◽  
Muscular Pain ◽  
Significant Difference ◽  
Group A ◽  
Group B

Scabies is a common health problem worldwide. Most treatment modalities available are topical. Among them 5% Permethrin isthe most effective scabicide with few side effects. Limiting factors are its high cost, cumbersome application and emerging resistance.Ivermectin is the only oral scabicide available. It is effective, inexpensive and easy to use drug with no known drug interactions and limited sideeffects. Objective of study: To compare the safety of topical Permethrin and oral Ivermectin in treatment of scabies. Study design: Quasiexperimentalstudy. Setting: Department of dermatology Jinnah Hospital, Lahore. Subjects: 120 patients were enrolled and were randomlydivided in 2 groups of 60 each. Duration:- 12-02-07 to 31-01-08. Non funded study (As ivermectin was not available in Pakistan during the studyperiod, it was imported from India as tablet Ivecop 12 mg). Methods: Topical Permethrin and oral Ivermectin were used in groups A and Brespectively. Patients were examined and certain investigations were carried out before dug administration, and at day 7 and day 14 to evaluatethe safety of both drugs on the basis of appearing of side effects and change in baseline investigations. Results: In both groups, equal numberof patients experienced side effects (n=15). In group A, side effects observed were burning (n=8), contact dermatitis (n=4) and stinging (n=3). Ingroup B, we observed muscular pain (n=5), nausea (n=5), headache (n=2) and others (n=3). Significant rise of hepatic enzymes was noticed inonly 1 patient of group B which improved on next follow up. Conclusions: We found no statistically significant difference regarding safety of usebetween permethrin and ivermectin.

scholarly journals Treatment of Periorbital dark circles: Comparative study of chemical peeling with a combination of trichloroacetic acid and lactic acid versus carboxytherapy

2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Arwa Mohammad Hassan ◽  
Ghada Fawzy Hassan ◽  
Hedaya Yousef Aldalies ◽  
Gamal Mohammad El Maghraby
Keyword(s):  
Lactic Acid ◽  
Trichloroacetic Acid ◽  
Treatment Session ◽  
Intradermal Injection ◽  
Autologous Fat Transplantation ◽  
Significant Difference ◽  
Chemical Peeling ◽  
Group A ◽  
Good Grade ◽  
Group B

<p>Periorbital dark circles (PODC) are a common worldwide cosmetic problem. It is difficult to treat due to complications in its pathogenesis and aetiology. Available lines of treatment for PODC include whitening creams, topical retinoid acid, chemical peeling, laser therapy, carboxytherapy, autologous fat transplantation, injectable fillers and surgery (blepharoplasty).The aim of this study isto evaluate and compare the efficacy of chemical peels using trichloroacetic acid (3.75%) and lactic acid (15%) in a gel formula with that of carboxytherapy, in the treatment of periorbital hyperpigmentation.Two groups of patients with PODC were included in the study, named Group A and B in which each group consisted of 15 patients. Group A was assigned for patients who received treatment with chemical peeling with a combination of trichloroacetic acid (3.75%) and lactic acid (15%) in a gel formula, once a week for four weeks. Group B was assigned for patients who received carboxytherapy that was performed by subcutaneous and intradermal injection of CO<sub>2</sub> once a week for four weeks. All patients were assessed by digital photographs, before and after treatment, by observing the improvement in the grade of PODC. Reports of patient satisfaction and global tolerance were evaluated by three medical observers. There was a significant improvement in the grade of PODC in both groups. The degree of improvement of PODC in group A was excellent, with good grade in 93.4% of the treated patients while fair grade in 6.6% of them. There was a statistically significant improvement in the pigmented type. The degree of improvement of PODC in group B was excellent, with good grade in 86.7% of the treated patients while fair grade in 13.3% of them. However, no statistically significant difference between the two groups was observed. Minimal and transient side effects were noticed; however, it did not require further treatment. In conclusion, the two methods of treatment were effective in the treatment of PODC, with the improvement of PODC observed from the first treatment session with both chemical peeling and carboxytherapy.</p>

COMPARATIVE STUDY IN BETWEEN INTRALESIONAL VITAMIN D3 AND INTRALESIONAL BLEOMYCIN IN THE TREATMENT OF CUTANEOUS VERRUCAE

2020 ◽  
Vol 4 (8) ◽  
Author(s):  
Shrikant . ◽  
R.D. Mehta ◽  
B.C. Ghiya
Keyword(s):  
Partial Response ◽  
Comparative Study ◽  
Recurrence Rate ◽  
Vitamin D3 ◽  
Complete Response ◽  
Recurrence Rates ◽  
Additional Advantage ◽  
Cost Effective Treatment ◽  
Group A ◽  
Group B

Background: Verruca is one of the common dermatopathologies which has multiple therapeutic options but with variable success rates, refractory cases and high recurrence rates. Nowadays, treatment with intralesional injections has gained recognition due to its effectiveness in clearing verrucae. These act by stimulating the cell-mediated immunity. Out of scores of options available for intralesional therapeutics, Vitamin D3 appears to be more promising but least evaluated. Therefore, we planned to evaluate the efficacy of intralesional Vitamin D3 in various types of cutaneous verrucae. Simultaneously the results were compared with intralesional bleomycin, also. Methods: A total of 200 patients of cutaneous verrucae with varying size and duration were included in the experimental randomized comparative study. We divided them into two groups. Group A, comprising of 100 patients, received 0.2-0.5 ml intralesional Vitamin D3 (600,000 IU, 15mg/ml) and Group B, also of hundred subjects, received intralesional Bleomycin (1 mg/ml) into the base of verrucae. A maximum of 5 verrucae were injected per session at 3 weeks interval until resolution or for a maximum of 4 sessions. Patients were followed up for 6 months after the last injection to assess the clearance status and detect any recurrence. Results: In Group A (Vitamin D3), 'Complete response', 'Partial response' and 'No response' were observed in 85.07%, 6.74% and 8.17% respectively after 4 sessions. Recurrence rate was 0.81% after 6 months. In Group B (Bleomycin), 'Complete response', 'Partial response' and 'No response' were found in 77.99%, 10.47% and 11.53% in the series. Recurrence rate was 1.71%, comparatively higher in group B. Conclusion: The efficacy of intralesional Vitamin D3 was found significantly higher as compared to intralesional Bleomycin in the treatment of cutaneous verrucae with less recurrence rates. Vitamin D3 has an additional advantage of cost-effective treatment over Bleomycin. We purpose its use, as a primary mode of treatment in various types of cutaneous verrucae. Keywords: Bleomycin, Vitamin D3, Verrucae.

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