scholarly journals The Adverse Effect Reporting for the Most Commonly Used Antibiotics

2020 ◽  
pp. 22-28
Author(s):  
Nehad J. Ahmed ◽  
Mohammed I. Fouda ◽  
Dina I. Fouda ◽  
Ahmed I. Foudah
Keyword(s):  
Saudi Arabia ◽  
Side Effects ◽  
Adverse Effects ◽  
Health Care Providers ◽  
Allergic Reactions ◽  
Care Providers ◽  
Drug Reactions ◽  
Antibiotic Drugs ◽  
Pharmacovigilance Center ◽  
Gastrointestinal Side Effects

Aim: Antibiotics save lives, but the excess use of antibiotics leads to more side effects. Patients benefit from medications but also complain about their adverse effects. This study aims to explore the reports of the adverse effects for the most commonly used antibiotics in Saudi Arabia. Methodology: The Data regarding the adverse events reports were collected from The National Pharmacovigilance Center in Saudi Arabia. The data include the major allergic reactions and gastrointestinal side effects for the most commonly used antibiotic classes. Results: The total number of allergic and gastrointestinal adverse effects in 2017 and 2018 for the included antibiotic drugs is 583 reports. The majority of the reports were for penicillin antibiotics (39.96) particularly Amoxicillin/Clavunate. Conclusion: The most common adverse effects of antibiotics are allergic and gastrointestinal effects. It is important to report any adverse drug reactions either by health care providers or patients to the Saudi Pharmacovigilance Center.

Risks of Cardiovascular Disease and Beyond in Prescription of Nonsteroidal Anti-Inflammatory Drugs

2019 ◽  
Vol 25 (1) ◽  
pp. 3-6 ◽  
Author(s):  
Manas A. Rane ◽  
Alexander Gitin ◽  
Benjamin Fiedler ◽  
Lawrence Fiedler ◽  
Charles H. Hennekens
Keyword(s):  
Cardiovascular Disease ◽  
Side Effects ◽  
Health Care Providers ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Care Providers ◽  
Relieve Pain ◽  
Gastrointestinal Side Effects ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) include aspirin, naproxen, diclofenac, and ibuprofen, as well as selective cyclooxygenase 2 inhibitors such as celecoxib. Their use is common, as well as their side effects which cause 100 000 hospitalizations and 17 000 deaths annually. Recently, the US Food and Drug Administration strengthened its warning about the risks of cardiovascular disease (CVD) attributed to nonaspirin NSAIDs. Methods: When the sample size is large, randomization provides control of confounding not possible to achieve with any observational study. Further, observational studies and, especially, claims data have inherent confounding by indication larger than the small to moderate effects being sought. Results: While trials are necessary, they must be of sufficient size and duration and achieve high compliance and follow-up. Until then, clinicians should remain uncertain about benefits and risks of these drugs. Conclusions: Since the totality of evidence remains incomplete, health-care providers should consider all these aforementioned benefits and risks, both CVD and beyond, in deciding whether and, if so, which, NSAID to prescribe. The factors in the decision of whether and, if so, which NSAID to prescribe for relief of pain from inflammatory arthritis should not be limited to risks of CVD or gastrointestinal side effects but should also include potential benefits including improvements in overall quality of life resulting from decreases in pain or impairment from musculoskeletal pain syndromes. The judicious individual clinical decision-making about the prescription of NSAIDs to relieve pain based on all these considerations has the potential to do much more good than harm.

scholarly journals Assessment of Females Awareness in Saudi Arabia about Long term use of COCP and Venous Thromboembolism Risk: A Cross Sectional Study

2021 ◽  
Vol 6 (01) ◽  
pp. 62-66
Author(s):  
Basmah Mohammed Alazmi ◽  
Shaikha Sulayyem Alsharari ◽  
Razan motawkel ◽  
Sara Alzahrani ◽  
Anhar Alfateel ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Side Effects ◽  
Sample Size ◽  
Health Care Providers ◽  
Cross Sectional Study ◽  
University Education ◽  
Care Providers ◽  
Sectional Study ◽  
Cross Sectional ◽  
Study Participants

Background: Nowadays there are a lot of women using contraceptive oral combined pills for birth control and as we know VTE is one of the complications when it used for a long time, and here in this study our aim is to assess the awareness and knowledge of females who live in Saudi Arabia about COCP and its complications like VTE. A cross-sectional observational study based on a questionnaire conducted among females who live in Saudi Arabia. Data collection was done by using online survey which contains questions about the age, education and contraception. Methods: An observational cross-sectional study carried out during December 2020 in Saudi Arabia. We minimize our target population through inclusion criteria: 1- Female 2- Live in Saudi Arabia 3- Agree to participate. Sample size was 454 participants calculated by using survey system website through sample size calculator with Confidence Level 95% and margin of error 5%. Result: A total of 454 patients completed the survey questionnaire. The results showed that the vast majority of the study participants aged 20 years or more. Moreover, more than 90% of the study participants were Saudi females. The average body weight is around 95 kg and height 164.2 cm. The results also indicated that two-third of the study participants attained university education level compared to 16.1% obtained secondary education. Additionally, 36.6% of the study participants worked as a housewife, 18.1% working in health field. Moreover, 40% of the respondents reside in the western regions, 34% live in eastern regions compared to the lowest percentage in South region 3.3%. Conclusion: In summary, this study revealed that the internet was the main source of knowledge. Health care providers should perform their intended role in improving the female’s awareness regarding family planning. The criteria for preferable contraceptive method are that it has few or no side effects, also it depends on how much effective and convenient it is. Educational programs may be warranted to minimize the fear of side effects and to enhance the general knowledge about contraception.

scholarly journals Canadian Expert Panel Recommendations on the Management of CNS Symptoms Related to Efavirenz

2001 ◽  
Vol 12 (suppl c) ◽  
pp. 20C-30C ◽  
Author(s):  
M John Gill ◽  
Anita Rachlis ◽  
Sharon Walmsley ◽  
Mark Halman ◽  
The Efavirenz Consensus Working Group
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Health Care Providers ◽  
Highly Active Antiretroviral Therapy ◽  
Primary Care Physicians ◽  
Sleep Disturbances ◽  
Present Report ◽  
Management Strategies ◽  
Routine Practice ◽  
Care Providers

Efavirenz is a potent antiretroviral agent used in combination with other antiretroviral agents as part of highly active antiretroviral therapy. Efavirenz is generally well tolerated because the majority of its adverse effects are self-limiting, with central nervous symptoms and rash being the most frequent. In routine practice, the discontinuation rate of efavirenz due to adverse effects appears higher than that described in clinical trials. To minimize early treatment interruption and maximize the benefit of long term viral suppression that can be achieved with efavirenz therapy, health care providers and patients have identified that there is a need for information, education about and practical tools for the management of efavirenz-related side effects. To this end, a panel of experts in the care of HIV patients consisting of primary care physicians, infectious disease specialists, psychiatrists and pharmacists was convened. Through the evaluation of current literature and discussion among the group, the panel arrived at consensus recommendations. The present report outlines general management recommendations that apply to adverse effects related to efavirenz initiation, as well as specific management strategies for central nervous system symptoms such as agitation, sleep disturbances, dreams, dizziness, impaired concentration and depression. It is hoped that these practical recommendations will aid clinicians in minimizing and improving patient tolerance of side effects, thereby achieving improved adherence and patient outcomes.

Radiation and its associated health risks: assessment of knowledge and risk perception among adolescents and young adults in Saudi Arabia

2018 ◽  
Vol 0 (0) ◽  
Author(s):  
Heba Shaaban ◽  
Mohsina Bano Shaikh
Keyword(s):  
Young Adults ◽  
Saudi Arabia ◽  
Health Care Providers ◽  
Daily Basis ◽  
Cross Sectional Study ◽  
Adolescents And Young Adults ◽  
Care Providers ◽  
Cross Sectional ◽  
Radiation Sources ◽  
Risks Assessment

Abstract Electromagnetic radiation is the fastest growing environmental factor due to the vast development in technology in the last decades. Awareness about radiation has received more attention worldwide due to its health hazards. Adolescents are exposed to radiation from various sources on a daily basis. The number of studies conducted to assess the knowledge and perception of adolescents and young adults regarding radiation and its risks is limited, especially in the Middle East. The aim of this study was to assess the knowledge and perception about radiation and its associated hazards among adolescents and young adults. Additionally, our aim was to identify the best methods of education regarding radiation and its protective measures. A cross-sectional study was conducted among 506 participants in Saudi Arabia. It was found that the overall knowledge and awareness on radiation sources and its hazards among adolescents and young adults is inadequate. The majority of participants had misconceptions regarding radiation sources and its detriments to health. Socio-demographic variables were associated with the participants’ perception. Educating adolescents on radiation and its safety measures is much needed. It was found that the most preferred methods of education are social media and health care providers. The findings of this study will provide insight when designing future interventions to promote specific messages to enhance knowledge and improve awareness regarding radiation.

scholarly journals IUCD-Related Knowledge, Attitudes and Practice among Primary Health Care Providers in Oman: Areas for Improvement

2020 ◽  
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Side Effects ◽  
Health Care Providers ◽  
Factual Knowledge ◽  
Care Providers ◽  
Primary Health ◽  
Attitude And Practice ◽  
Primary Health Care Providers ◽  
Knowledge Attitude And Practice

Objectives: The primary objective of this study is to assess three domains - the knowledge, attitude and practice related to the Intrauterine Contraceptive Device (IUCD) among primary health care providers (physicians and nurses) in Oman. The secondary objective is to compare the IUCD-related knowledge, attitude and practice of health care providers in primary health care between physicians and nurses. Methods: A descriptive cross-sectional survey was conducted in primary health care centers in Muscat region of Oman from May, 2014 until September, 2015. The survey was a self-administered questionnaire contained questions to assess factual knowledge, attitudes and practice of IUCD. The questionnaire was distributed to female health care providers only. Data was collected by researchers and analyzed using SPSS version 20. Results: Total 269 primary health care providers completed the questionnaire. 109 (40.52%) participants had good and 131 (48.70%) had average actual knowledge related to IUCD. The main reasons providers cited for not recommending the IUCD were concerns about the side effects; 174 (64.68%) mentioned that it causes bleeding and 127 (47.21%) reported that it needs service provider. Only 140 (52.43%) of the providers would routinely recommend IUCD to their clients. Conclusion: Future educational programs for health care providers should address the educational needs in the identified areas including misconceptions with regards to IUCD failure rate and side effects. Future training programs are also required to increase the technical competence of insertion and confidence in handling the side effects of IUCD.

Current Practices of Antiseptic Use in Canadian Neonatal Intensive Care Units

2018 ◽  
Vol 36 (02) ◽  
pp. 141-147 ◽  
Author(s):  
Helen McCord ◽  
Elise Fieldhouse ◽  
Walid El-Naggar
Keyword(s):  
Intensive Care ◽  
Adverse Effects ◽  
Intensive Care Units ◽  
Health Care Providers ◽  
Neonatal Intensive Care ◽  
Chlorhexidine Gluconate ◽  
Neonatal Intensive Care Units ◽  
Care Providers ◽  
Level Ii ◽  
Canadian Provinces

Objective This article assesses the degree of variability in the current practice of skin antiseptics used in Canadian neonatal intensive care units (NICUs) and different experiences related to each antiseptic used. Methods An anonymous survey was distributed to a clinical representative of each of the 124 Canadian level II and level III NICUs. Results One hundred and two respondents (82.2%), representing all Canadian provinces, completed the survey. Chlorhexidine gluconate with/without alcohol was the antiseptic most used (96%) and the antiseptic with the highest reported adverse effects (68% reported skin burns/breakdown). Other antiseptics used include povidone-iodine (35%) and isopropyl alcohol (22%). Specific guidelines for antiseptic use were available in only 50% of the units with many NICUs lacking gestational and/or chronological age restrictions. Only 23% of responders believed that there was awareness among health care providers of the adverse effects of antiseptics used. Less than half (43%) were completely satisfied with the antiseptics used in their units. Conclusion Chlorhexidine gluconate is the most commonly used antiseptic in Canadian NICUs. The high number of associated adverse effects and the lack of guidelines regulating antiseptic use are of concern. Large clinical trials are urgently needed to guide practice and improve the safety of antiseptics.

scholarly journals Prevalence of Depression, Anxiety, and Stress among the General Population in Saudi Arabia during Covid-19 Pandemic

2020 ◽  
Vol 17 (24) ◽  
pp. 9183
Author(s):  
Hasan Saeed Alamri ◽  
Abdullah Algarni ◽  
Shehata F. Shehata ◽  
Ali Al Bshabshe ◽  
Nada N. Alshehri ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
General Population ◽  
Health Care Providers ◽  
Psychological Impact ◽  
Public Mental Health ◽  
Well Being ◽  
Risk Groups ◽  
Care Providers ◽  
Cross Sectional ◽  
Prevalence Of Depression

Coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on public mental health. Our objective was to assess prevalence of depression, anxiety, and stress among the general population in Saudi Arabia during this pandemic. A descriptive cross-sectional approach was used targeting all accessible populations in Saudi Arabia. Data were collected from participants using an electronic pre-structured questionnaire. Psychological impact was assessed using the Arabic version of Depression, Anxiety, and Stress Scale (DASS-21). A total of 1597 participants completed the survey. In total, 17.1% reported moderate to severe depressive symptoms; 10% reported moderate to severe anxiety symptoms; and 12% reported moderate to severe stress levels. Depression, anxiety, and stress were significantly higher among females, younger respondents, and health care providers. Depression was higher among smokers, singles, and non-working respondents. Anxiety was higher among those reporting contacts with COVID-19 positive cases, previously quarantined and those with chronic health problems. Our findings reaffirm the importance of providing appropriate knowledge and specialized interventions to promote the mental well-being of the Saudi population, paying particular attention to high-risk groups.

Course in Prehospital Major Incidents Management for Health Care Providers in Saudi Arabia

2018 ◽  
Vol 33 (6) ◽  
pp. 587-595 ◽  
Author(s):  
Nidaa A. Bajow ◽  
Wajdan I. AlAssaf ◽  
Ameera A. Cluntun
Keyword(s):  
Health Care ◽  
Saudi Arabia ◽  
Health Care Providers ◽  
Core Competencies ◽  
Wilcoxon Test ◽  
Major Incident ◽  
Incident Management ◽  
Care Providers ◽  
Post Test ◽  
Major Incidents

AbstractIntroductionUnacceptable practices of health care providers during disasters have been observed because they work outside the scope of their daily practices and have inadequate training. A greater need for the involvement of health professionals in disaster management has been noted in Saudi Arabia. This study evaluates the efficacy of a training course in prehospital major incident management for health care providers in Saudi Arabia.MethodsAn interactive course for general principles in prehospital major incident management was developed with domains and core competencies. The course was designed according to the local context and was based on international standards. It was piloted over four days at the Officers Club of the Ministry of Interior (Riyadh, Saudi Arabia) and was sponsored by Mohammed Bin Naif Medical Center, King Fahd Security College in Riyadh, Saudi Arabia. The participants (n=29) were from different disciplines from main government health facilities in Riyadh. They completed a pre-test and a post-test.ResultsThe overall score was 55.1% on the pre-test and 68.4% on the post-test (Wilcoxon test for paired samples, P <.05). Three out of the four domains had significant difference between pre- and post-test results, as well as the overall total knowledge.Conclusion:Conducting inter-disciplinary and competency-based disaster medicine courses for health care providers can augment appropriate disaster preparedness for major incidents in Saudi Arabia.BajowNA,AlAssafWI,CluntunAA.Course in prehospital major incidents management for health care providers in Saudi Arabia.Prehosp Disaster Med.2018;33(6):587–595.

scholarly journals Anti-retro viral therapy adverse drug reaction and associated factors among human immuno deficiency virus infected adult patients at Nigist Eleni Mohammed Memorial hospital, South Ethiopia

2020 ◽  
Vol 20 (2) ◽  
pp. 560-567
Author(s):  
Temesgen Tamirat ◽  
Kifle Woldemichael ◽  
Tsegaye Tewelde ◽  
Tariku Laelago
Keyword(s):  
Adverse Drug Reactions ◽  
Health Care Providers ◽  
Associated Factors ◽  
Adult Patients ◽  
Hiv Care ◽  
Stage Iii ◽  
Memorial Hospital ◽  
Care Providers ◽  
Drug Reactions ◽  
Infected Adult

Background: Recent increases in access to HAART have made the management of drug toxicities an increasingly crucial component of HIV care in developing countries. The aim of this study was to determine prevalence of antiretroviral ther- apy adverse drug reactions and associated factors among HIV-infected adult patients at Nigist Eleni Mohammed memorial hospital. Methods: A cross sectional study was conducted by retrospective review of patients’ medical records. From a total 721 adult patient records, 231 patients record were selected by simple random sampling technique. The study was conducted April15-25, 2015.The association between dependent and independent variables was measured by using OR at 95% CI. P-value <0.05 was considered as statistically significant. Result: About 53(22.9%) patients developed ADRs (adverse drug reactions). Female (AOR=2.72, CI=1.177-6.30), patients with WHO stage III and IV (AOR= 13.06, CI=4.17- 40.90) were found more likely to develop ADRs. Commonly identified ADRs were fatigue (18.1%), diarrhea (7.7%), nausea (6.5%), headache (3.6%) and anemia (2%). Conclusion: Nearly one in five patients develop ADRs. Sex of respondents, WHO stage and functional status were asso- ciated with ADRs. The health care providers should give due attention to ambulatory, bedridden, and WHO stage III and IV patients. Keywords: ART; HIV; AIDS; Ethiopia.

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