scholarly journals Race as Determinant of Red Blood Cell Osmotic Stress Haemolysis in South Indian and African Populations

2021 ◽  
pp. 46-52
Author(s):  
Hassan Thabit Haji ◽  
Chukwuma J. Okafor ◽  
Emmanuel Ifeanyi Obeagu ◽  
Othman Hakum Said ◽  
Kirtana R. Nayak ◽  
...  
Keyword(s):  
Osmotic Stress ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Osmotic Fragility ◽  
Total Sample ◽  
Cross Sectional Study ◽  
South Indian Population ◽  
Cross Sectional ◽  
South Indians ◽  
South Indian

The study was to compare the red blood cell osmotic fragility between South Indian and African ethnicities. A cross sectional study was performed in the Department of Physiology, Kasturba Medical College, Manipal. The study involved apparently healthy young adults between 18 to 40 years old. The whole study's total sample size was 50 healthy individuals, 25 South Indians (13 female and 12 male) and 25 Africans (13 female and 12 male).  The results showed an increase in the percentage haemolysis that was statistically significant (p=0.0001) in South Indians (32.16 ±5.048%) compared to Africans (20.01 ± 3.151%), respectively. The present study has identified and quantified race's impact as one of the determinant factors of red blood cell osmotic stress haemolysis. Therefore, we conclude that the percentage of haemolysis is higher for the South Indian population than the African population.

scholarly journals Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study

2021 ◽  
Vol 10 (11) ◽  
pp. 2475
Author(s):  
Olivier Peyrony ◽  
Danaé Gamelon ◽  
Romain Brune ◽  
Anthony Chauvin ◽  
Daniel Aiham Ghazali ◽  
...  
Keyword(s):  
Emergency Department ◽  
Logistic Regression ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cross Sectional Study ◽  
Red Blood Cell Transfusion ◽  
Cross Sectional ◽  
Acute Bleeding ◽  
History Of ◽  
Rbc Transfusion

Background: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. Methods: This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion Hb level ≥ 8 g/dL. Results: During the study period, 529 patients received RBC transfusion. The median age was 74 (59–85) years. The patients had a history of cancer or hematological disease in 185 (35.2%) cases. Acute bleeding was observed in the ED for 242 (44.7%) patients, among which 145 (59.9%) were gastrointestinal. Anemia was chronic in 191 (40.2%) cases, mostly due to vitamin or iron deficiency or to malignancy with transfusion support. Pre-transfusion Hb level was 6.9 (6.0–7.8) g/dL. The transfusion motive was not notified in the medical chart in 206 (38.9%) cases. In the multivariable logistic regression, variables that were associated with a higher pre-transfusion Hb level (≥8 g/dL) were a history of coronary artery disease (OR: 2.09; 95% CI: 1.29–3.41), the presence of acute bleeding (OR: 2.44; 95% CI: 1.53–3.94), and older age (OR: 1.02/year; 95% CI: 1.01–1.04). Conclusion: RBC transfusion in the ED was an everyday concern and involved patients with heterogeneous medical situations and severity. Pre-transfusion Hb level was rather restrictive. Almost half of transfusions were provided because of acute bleeding which was associated with a higher Hb threshold.

scholarly journals The Palmar Dermatoglyphic Patterns in Type II Diabetes Mellitus Cases- A Study in South Indian Population

2021 ◽  
Vol 14 (01) ◽  
pp. 379-383
Author(s):  
Akshai Lekshmi P ◽  
T Srimathi ◽  
V S Anandarani
Keyword(s):  
Diabetes Mellitus ◽  
Early Diagnosis ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
South Indian Population ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
South Indian ◽  
Group A

Diabetes mellitus [DM] is a major disease worldwide with increasing prevalence. Its etiologic heterogeneity comprising genetic predisposition and environmental factors may provide a characteristic feature among the population helpful for the early diagnosis. This study aims to evaluate the palmar dermatoglyphic patterns in DM patients. This case controlled cross-sectional study included 100 type 2 DM patients in group A and 100 healthy subjects in group B. Each group has equal gender distribution. The palmar dermatoglyphics were evaluated quantitatively using standard methods. Student’s t-test and Chi-square test was used to determine the level of significance. The palmar triradius number varied significantly (Pd”0.0001). The angle of palm variations were statistically insignificant between groups, but TAD angle showed significant gender variations in group A patients (Pd”0.0001). The variation in palmar triradius revealed in this study may help in early diagnosis of type 2 DM patients and also may provide a scope for further studies with larger sample size.

scholarly journals Psoriasis and metabolic syndrome: hospital based cross sectional study of prevalence and correlation in a rural south Indian population

2016 ◽  
Vol 2 (3) ◽  
pp. 49
Author(s):  
Dhanalakshmi Kathirvel ◽  
Vaishnavi Dhandapani ◽  
Baskaran R. ◽  
Gladius Jennifer H.
Keyword(s):  
Metabolic Syndrome ◽  
Lifestyle Modification ◽  
Normal Population ◽  
Cross Sectional Study ◽  
South Indian Population ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
South Indian ◽  
Chi Square Test

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic inflammatory skin disease that affects 1-3% of the population. Recent studies have reported that psoriasis is associated with metabolic disorders, including obesity, dyslipidaemia and diabetes. The aim of the present study was to investigate the prevalence of metabolic syndrome (MS) in psoriasis and to evaluate the association with severity and duration of psoriasis</p><p class="abstract"><strong>Methods:</strong> This was a hospital based cross sectional study that involved 60 patients with psoriasis evaluated for MS. Statistical analysis was done by SPSS version 16.0 software. Percentages, mean, standard deviation, correlation, chi-square test, t test were calculated at 5% level of significance.<strong></strong></p><p class="abstract"><strong>Results:</strong> 20% of patients had MS which is comparable to the normal population. 60% of the patients in our study are obese which is directly correlating with MS. There is significant increase in MS as age (p =0.01), duration of psoriasis (p =0.03), BMI (p =0.0001), waist circumference (p =0.0001) increases.</p><p><strong>Conclusions:</strong> There is 20% association of psoriasis with MS. There is no gender predisposition and no association between the severity of psoriasis and metabolic syndrome. There is minimal relationship between the duration of psoriasis and metabolic syndrome. Obesity is the commonest factor related to psoriasis, diabetes and MS which should be taken care of by diet, exercise and lifestyle modification. </p>

scholarly journals Factors associated with red blood cell transfusion among hospitalized patients: a cross-sectional study

2021 ◽  
Vol 22 (12) ◽  
pp. 1060-1064
Author(s):  
Peiwen Zhang ◽  
Dandan Xu ◽  
Xinhan Zhang ◽  
Mengyin Wu ◽  
Xuecheng Yao ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cross Sectional Study ◽  
Hospitalized Patients ◽  
Red Blood Cell Transfusion ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

scholarly journals ASSESSMENT ON IMPACT OF COVID 19 PANDEMIC ON FEAR AND SOCIOECONOMIC STATUS AMONG SOUTH INDIAN POPULATION

2020 ◽  
pp. 52-56
Author(s):  
SREEJA NYAYAKAR ◽  
MUTHUKUMAR M. ◽  
LATHA SREE MOOTHI
Keyword(s):  
Socioeconomic Status ◽  
Family Life ◽  
Indian Population ◽  
Cross Sectional Study ◽  
South Indian Population ◽  
Cross Sectional ◽  
South Indian ◽  
Study Population ◽  
General Populations ◽  
The Impact

Objective: To assess the impact of the COVID 19 pandemic on fear and socioeconomic status among the south Indian population. Methods: A prospective observational cross-sectional study was conducted on 18-year old and older people who are willing to fill the online form were included in the study. People who are not willing to fill the form and those who filled the forms incompletely were excluded from the study. Microsoft Excel was used for recording and analyzing the data of recruited subjects. Descriptive statistical analyses were used to calculate the average and standard deviation. Results: In total 476 respondents were included in the study to make the results. From the 476 respondents, 53.9% were males and 43.4% were females, 43.4% of individuals were satisfied with family life, 31.7% of individuals were satisfied with their salary, 37.3% of individuals were satisfied with their economic position, 55.2% of individuals were satisfied with their health and 50.4% of individuals were satisfied with their life in general. Conclusion: Our study concludes that young students are showing more interest in online surveys among other general populations and data concludes that fear about the infection was less among the study population. More than half of the participants are concerned about their salary and most of the participants are not feared about their family life and their health.

Sign in / Sign up

Export Citation Format

Share Document