scholarly journals Comparative Study between Modified Transverse and Hayman Suture Regarding the Efficacy and Purperium Complications in Thi-Qar

2021 ◽  
pp. 22-33
Author(s):  
Aseel Mosa Jabber
Keyword(s):  
Statistical Difference ◽  
Post Partum ◽  
High Rate ◽  
P Value ◽  
Post Partum Hemorrhage ◽  
Significant Statistical Difference ◽  
Surgeon Experience ◽  
Compression Suture ◽  
Uncontrolled Hemorrhage

Background: Main causes of death post-partum is the uncontrolled hemorrhage, that managed by different modalities, whereuterine compression suture had different efficacies as a main interventional tools of sever postpartum hemorrhage. Aim: comparing different sutures types (modified transverse and Hayman suture) regarding their efficacy through its impact and in determining the final outcome and complications of post-partum hemorrhage. Materials and methods: A prospective comparative analytical study including 122 females , who underwent delivery between march 2017and December 2019, all of them followed for , 1 week, 6,weeks 6 months. Were the samples collected from Bent-Al-Huda teaching hospital and Al-Rehman private hospital-Thi-Qar, 2 groups of study; 1st one (52) underwent modified B-lynch suturing (Hyman suturing) while the 2nd group(70) underwent transverse sutures of modified Ouahba suture, written consent had taken from all patients, SPSS version 24 used for analysis. Results: Among 122 delivered women suffer from primary post-partum hemorrhage, 52 (42.63%) were sutured by Hayman suture, and 70 (57.37%)were sutured by transverse suturing,There was significant statistical difference between the types of intervention and blood loss P value <0.05. There was significant statistical difference between the types of intervention and complication development (p value=0.0001). There was no significant independent predictors or determinant for the complication development except the type of intervention. Only follow-up period and complication were truly to be correlated with type of intervention, the other variable were confounders Conclusion: Even though the hemostasis had been achieved in both maneuver with excellent success rate, the transvers suture carrying high rate of persistent pain but the Hayman suture carry higher rate of serious complication such hysterectomy and intestinal obstruction. several factors determine the choosing of the suture type such as site, severity and cause of bleeding and the surgeon experience.

scholarly journals Management of refractory atonic post partum hemorrhage by upper segment compression suture

2016 ◽  
Vol 11 (3) ◽  
Author(s):  
Rakhshanda Toheed ◽  
Naela Tarique ◽  
Saqib Siddique
Keyword(s):  
Medical Treatment ◽  
Post Partum ◽  
Medical Institute ◽  
Effective Technique ◽  
Post Partum Hemorrhage ◽  
Uterine Massage ◽  
Compression Suture ◽  
Complex Surgical Procedures ◽  
Normal Menstruation

Aims: The study was undertaken to test the efficacy of Upper Segment Compression Suture(USC Suture) for the control of atonic post partum hemorrhage unresponsive to medical treatment. Study Design: Observational study. Duration:: From March 1998 to March 2003. Setting: Department of Obstetrics & Gynaecology, Lahore General Hospital , Post Graduate Medical Institute, Lahore, Pakistan. Subjects: Fourteen women with atonic PPH refractory to medical treatment. Results:: Fourteen women with severe atonic PPH were managed using uterine massage and utero tonic drugs. Failing these measures, Upper Segment compression suture was used as first line conservative surgical technique. There was no relaparotomy for recurrent PPH. All cases were managed successfully avoiding hysterectomy or other complex surgical procedures. Recovery in all cases was uneventful.Long term follow up was available in four cases. All were having normal menstruation. Two o f them achieved spontaneous pregnancies. Conclusion:: Upper Segment Compression Suture is an effective technique for managing refractory PPH caused by uterine atony.

scholarly journals Comparison of Phacotrabeculectomy and Phacotrabeculectomy with Subconjunctival 5-Fluorouracil

2014 ◽  
Vol 52 (196) ◽  
pp. 1010-1013
Author(s):  
Nanda Kumari Gurung ◽  
Prachand Gautam ◽  
Shanti Gurung ◽  
Binita Bhattarai
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Statistical Difference ◽  
Surgical Techniques ◽  
Significant Statistical Difference ◽  
Keywords Glaucoma ◽  
Group A ◽  
Group B ◽  
Age Range

Introduction: Glaucoma is the second leading cause of blindness worldwide. Phacotrabeculectomyis a technique in which glaucoma and cataract surgery performed. Methods: Prospective study was carried out in the department of glaucoma at Lumbini Eye Institute, Bhairahawa.100 patients who underwent phacotrabeculectomy within a period of two years. Patients were divided into two groups those who received 5FU (n=47) and no antifibrotic agent (n= 53). Results: The age range was from 38 to 80 years; mean age of 62.97±9.14 SD. 55% were male and 45% were female.The postoperative IOP reduction in last follow- up group A was mean=13.08±1.57SD and mean=13.23±1.73SD in group B. This was statically significant with P <0.001. Bleb survival was almost similar in two groups 3.17(78.31%) in group A and 3.20 (78.93%) in group B. 85% visual acuity was improved in both groups. Conclusions: Phacotrabeculectomy and phacotrabeculectomy with inj. 5FU, both were equally effective surgical techniques in terms of visual acuity, IOP control and bleb survival.There was no significant statistical difference vis-à-vis the success of Phacotrabeculectomy using of either these two techniques.  Keywords: glaucoma; 5FU; intraocular pressure; phacotrabeculectomy.

scholarly journals A prospective observational study involving three fixed infusion regimens of phenylephrine for hemodynamic support during spinal anaesthesia for caesarian delivery

2019 ◽  
Vol 8 (6) ◽  
pp. 2293
Author(s):  
Aymen Masood ◽  
Ajaiz Rasool ◽  
Aabid Hussain Mir ◽  
Waqurl Neesa ◽  
Ayaz Farooqi
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Placebo Group ◽  
Side Effects ◽  
Spinal Anaesthesia ◽  
Statistical Difference ◽  
P Value ◽  
Significant Statistical Difference ◽  
Umbilical Blood ◽  
Phenylephrine Infusion

Background: Spinal anaesthesia used in caesarian section is associated with hypotension which can have maternal and fetal side effects. To determine the efficacy and ideal dosing of Phenylephrine in attenuating the hypotensive episodes during caesarean section under spinal anaesthesia.Methods: 100 patients were allocated to four groups, placebo group (PE 0) and 3 fixed phenylephrine infusion regimens, phenylephrine 25 μg/min-1 (PE 25), phenylephrine 50 μg/min-1 (PE 50), and phenylephrine 75 μg/min-1 (PE 75). Blood pressure, heart rate were noted among primary variables and fetal parameters like umbilical blood pH and lactate were recorded as secondary parameters.Results: There was a significant reduction in heart rate with increasing the infusion dosage of phenylephrine, with a mean of 86.8 beats/min at the end of procedure in placebo group and 69.4 beats/min in 75 μg group (p value <0.001). There was significant statistical difference among systolic blood pressure in the four groups after 7 min of the procedure and p-value of <0.05 with better attenuation of hypotension in infusion groups as compared to placebo. Similarly there was significant statistical difference in diastolic blood pressure among the four groups after 8 min of the procedure with p values <0.05.Conclusions: Prophylactic phenylephrine infusions reduced the incidence and severity of maternal pre-delivery hypotension. Among the fixed rate phenylephrine infusion regimens investigated, infusion rates of 50 μg/min-1 were associated with greater maternal hemodynamic stability compared with 25 and 75 μg/min-1, with minimal side effects and intervention.

Galectin-1 Is Overexpressed in Myeloid Cells and There Is a Significant Different Overexpression in Cells Carrying the BCR-ABL Chimeric Gene.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 4383-4383
Author(s):  
Enrica Lerma
Keyword(s):  
Gene Expression ◽  
T Cell ◽  
Cancer Progression ◽  
Time Course ◽  
Statistical Difference ◽  
Myeloid Cells ◽  
T Test ◽  
Chimeric Gene ◽  
P Value ◽  
Significant Statistical Difference

Abstract The galectins are a family of lectins, beta-galactoside sugar chain binding proteins, that have been identified as mediator of cell adhesion, cell growth regulators, and as triggers or inhibitors of apoptosis. Their expression pattern is deregulated during inflammation and in breast, colon, prostate, and thyroid cancers and their overexpression correlates to metastatic potential. Galectin-1 is a pleiotropic dimeric protein participating in cancer progression. The gene encoding galectin-1 is located in an 11-kb region on chromosome 22q13.1. Induction of apoptosis in activated T lymphocytes is a well-known function of this galectin. The association of accumulation of galectin-1 in the stroma of malignant tissue and aggressiveness of the tumor suggested a role for this lectin in the acquisition of the invasive phenotype and may act as an immunological shield by inducing activated T-cell apoptosis. To be susceptible to galectin-1 induced apoptosis, the T cell must express specific glycoprotein receptors, such as CD7, that bear the specific oligosaccharides recognized by galectin-1. The sensitivity to galectin-1 is associated with repression of the endogenous galectin-1 gene whereas non-sensitive cells express high levels of galectin-1. The current analysis has been performed in myeloid cells negative or positive for BCR-ABL, a chimeric gene derived by the t(9;22), that is present in chronic myeloid leukemia patients. The BCR-ABL gene, the expression of which was governed by the tetracycline inducible promoter, has been introduced by transfection in a myeloid cell line. Total RNA for microarray analysis, in presence or absence of BCR-ABL gene expression, has been isolated. The comparison involved ~5300 transcripts. A comprehensive galectin fingerprinting in these cells by microarray gene expression analysis to define the pattern in BCR-ABL positive and negative cells has been done. The results showed in the table clearly demonstrated that myeloid cells express more mRNA species for galectin-1 than for galectin-9 while none of the other lectins belonging to this family are expressed in either BCR-ABL positive or negative cells. A significant statistical difference has been found between the levels of expression of galectin-1 compared to galectin-9. A higher significant statistical difference has been found in the levels of galectin-1 overexpression in BCR-ABL positive cells. To better understand the preliminary data, a time course after the addition of tetracycline to the 32Dtetp210Bcr-Abl cells has been carried out. This last experiment demonstrated that galectin expression levels decrease over 18 hours and the expression of galectin-9 is already absent after 6 hours from the addition of tetracycline to the culture medium while the expression of galectin-1 is still present after 12 hours but at a level comparable to normal cells. These results might suggest a role for the modulation of galectin-1 activity as a new strategy for molecular treatment of BCR-ABL positive leukemia. Galectins gene expression profile in myeloid cells BCR-ABL negative BCR-ABL positive raw t-test p-value flags raw t-test p-value flags Gal9 776 0,238 P 520,2 0,347 P Gal7 15,8 0,874 A 13,2 0,849 A Gal6 39,6 0,928 A 61,9 0,962 A Gal8 71,2 1 A 51,2 0,937 A Gal3 6 0,853 A 4,6 0,83 A Gal1 5.652,80 0,0315 P 12.087,30 0,0142 P

scholarly journals Clinical Effectiveness of Gingival Depigmentation Using Conventional Surgical Scrapping and Diode Laser Technique: A Quasi Experimental Study

2016 ◽  
Vol 9 (3) ◽  
pp. 296 ◽  
Author(s):  
Reddy Nagati Raghavendra ◽  
M. Ragul ◽  
Al-Qahtani Nabeeh ◽  
K. S. Ravi ◽  
S. Tikare ◽  
...  
Keyword(s):  
Diode Laser ◽  
Statistical Difference ◽  
Clinical Effectiveness ◽  
Patient Comfort ◽  
Patient Acceptance ◽  
P Value ◽  
Laser Technique ◽  
Gingival Bleeding ◽  
Gingival Depigmentation

<p>Excessive gingival pigmentation is a major aesthetic concern in modern society, though it is not a medical problem they consider it as a negative attribute. Patients with gingival hyperpigmentation usually complain and request cosmetic therapy, particularly if the pigmentation is visible during speaking and smiling. Various depigmentation methods, including burr abrasion, cryosurgery, electro-surgery, split thickness flap excision and surgical scraping techniques have been used with varying degrees of success. Recently, lasers have been used to ablate cells containing and producing the melanin pigment. The present study was undertaken to compare the clinical effectiveness and patient comfort of surgical scrapping and diode laser technique used for gingival depigmentation for a follow up period of 6 months.20 subjects participated in this split mouth study. The clinical evaluation parameters included Extent and Intensity of gingival hyperpigmentation, post-operative gingival bleeding and pain. On follow up examination at 6<sup>th</sup> month there was no statistical difference in repigmentation extent and intensity between diode laser and surgical scraping techniques. The mean pain scores for treated sites with diode laser were significantly lower than surgical scrapping technique at 24 hours (t-value=2.430, p-value=0.02). The postoperative gingival bleeding at end of procedure was significantly lower with diode laser than surgical scrapping technique (p-value=&lt;0.0001). There was no statistical difference in postoperative re-pigmentation and clinical efficacy among the subjects between surgical scraping and diode laser technique at 6<sup>th</sup> month follow up. Diode laser technique provides better haemostasis and good visibility at the surgical site. The post-operative patient comfort is better at the surgical sites treated with diode laser than surgical scrapping method. Hence, both the techniques are used for depigmentation procedures depending on the severity and gingival biotype and patient acceptance.</p>

THE PROTECTIVE STATUS OF SUBTOTAL OBLITERATION OF ARTERIOVENOUS MALFORMATIONS AFTER RADIOSURGERY

Neurosurgery ◽  
2009 ◽  
Vol 65 (4) ◽  
pp. 709-718 ◽  
Author(s):  
Zuair Abu-Salma ◽  
François Nataf ◽  
May Ghossoub ◽  
Michel Schlienger ◽  
Jean-François Meder ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Arteriovenous Malformations ◽  
Statistical Difference ◽  
Bleeding Rate ◽  
Significant Statistical Difference ◽  
Significant Difference ◽  
Complete Obliteration

Abstract OBJECTIVE Arteriovenous malformations (AVMs) treated by radiosurgery with complete obliteration of the nidus but a persisting early draining vein on follow-up angiography can be termed subtotally obliterated. However, these are persistent circulating AVMs. The significance of these lesions, their hemorrhage rate, and their management are analyzed. METHODS In a series of 862 consecutive patients with AVMs treated by radiosurgery, 121 patients (14%) achieved subtotal obliteration (STO). The angiographic evolution and rate of obliteration were studied. The pretreatment angiographic features, dosimetric parameters, and postradiosurgery hemorrhage rate were compared with those in the rest of the treated population. Finally, the options for follow-up and treatment were analyzed. RESULTS Of 121 subtotally obliterated AVMs, the bleeding rate was 0%; 53% of patients achieved complete obliteration. This occurred in 71% of those who had STO at 1 year. In the cases in which STO was detected at 2, 3, and 4 years, total obliteration eventually occurred in 43%, 28.5%, and 0%, respectively. Comparative analysis with AVMs in which a part of the nidus persisted showed a significant difference in the bleeding rate. Except for volume, no significant statistical difference in angiographic and dosimetric parameters was found between the STO group and the rest of the studied population with residual nidus. Six cases received further treatment, resulting in 2 cures and 2 treatment-related complications. CONCLUSION Subtotally obliterated AVMs are different from other partially obliterated AVMs, with a 0% bleeding rate. Their complete obliteration is a function of delay of appearance on follow-up angiography. Invasive follow-up and further treatment of these AVMs do not seem warranted.

scholarly journals ASSESSMENT OF FLOW MEDIATED DILATATION OF BRACHIAL ARTERY BY ANGIODEFENDER DEVICE AS COMPARED TO BRACHIAL ARTERY ULTRASOUND IMAGING.

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Mukesh Kumar Sharma ◽  
Chandra Bhanu Chandan ◽  
Abhishek Shukla ◽  
Deepak Ameta ◽  
Pradeep Kurmi
Keyword(s):  
Correlation Coefficient ◽  
Ultrasound Imaging ◽  
Brachial Artery ◽  
Statistical Difference ◽  
P Value ◽  
Positive Correlation ◽  
Significant Statistical Difference ◽  
Flow Mediated Dilatation ◽  
The Mean ◽  
Flow Mediated Vasodilation

Aims & Objectives: To demonstrate, Angiodefender device, is comparable to “Brachial artery ultrasound imaging” (BAUI) in their abilities to quantify percentage flow mediated vasodilation (FMD) of the brachial artery. Methods: Study was conducted on 100 patients, flow mediated vasodilation was measured by BAUI as well as by the Angiodefender device and the results were compared. Results: The mean %FMD measured by the BAUI was found to be 7.46 ±  4.21 whereas mean %FMD measured by the Angiodefender was 8.24 ±  2.46, (p value 0.113). Positive correlation was found between both the tests with correlation coefficient of 0.65, p value < 0.0001 which is highly significant. Conclusion: Results obtained by both the methods were comparable there was no significant statistical difference. Positive correlation was highly significant between both the tests with correlation coefficient of 0.65. Keywords: Brachial artery ultrasound imaging, Angiodefender, Flow mediated vasodilation

scholarly journals Hubungan Paritas, Umur Ibu Dengan Perdarahan Post- Partum Primer di Rumah Sakit Panti Rapih Yogyakarta Tahun 2017- 2018

2021 ◽  
Vol 1 (2) ◽  
pp. 111-120
Author(s):  
Theresia Heni Lestari ◽  
Theresia Endah Marianingsih ◽  
Yuliasti Eka Purnamaningrum
Keyword(s):  
At Risk ◽  
Significant Relationship ◽  
Maternal Age ◽  
Post Partum ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Live Births ◽  
Post Partum Hemorrhage ◽  
Chi Square Test

Background: The cause of AKI in DIY 2018, 11% of post-partum hemorrhage, with a gap in MMR target and achievement <102 / 100,000 live births, MMR in 2018: 111.5 / 100,000 live births, indicating an increase in MMR. In the same year at Panti Rapih Hospital, there was an increase in the incidence of post-partum hemorrhage by 6%, with 62.8% of parity at risk, 53.5% of age at risk. Objective: of the study was to determine the relationship between parity and maternal age with the incidence of primary post-partum hemorrhage at Panti Rapih Hospital in 2017-2018. Methods: observational, cross sectional design, sample 43 people. Chi Square Test data analysis. Results: There was a significant relationship between parity and the incidence of primary post partum hemorrhage (p-value = 0.011). There was a significant relationship between age and the incidence of primary post-partum hemorrhage at Panti Rapih Hospital (p-value = 0.014). Conclusion: There is a significant relationship between parity, maternal age <20 years or> 35 years with the incidence of primary post partum hemorrhage at Panti Rapih Hospital in 2017-2018.

Simpler compression suture for controlling atonic post-partum hemorrhage

2015 ◽  
Vol 41 (6) ◽  
pp. 993-994 ◽  
Author(s):  
Guang-Tai Li ◽  
Xiao-Fan Li ◽  
Guangrui Li
Keyword(s):  
Post Partum ◽  
Post Partum Hemorrhage ◽  
Compression Suture
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