scholarly journals Transfiguring Healthcare: Three-Dimensional Printing in Pharmaceutical Sciences; Trends during COVID-19: A Review

2021 ◽  
pp. 207-218
Author(s):  
K. G. Siree ◽  
T. M. Amulya ◽  
T. M. Pramod Kumar ◽  
S. Sowmya ◽  
K. Divith ◽  
...  
Keyword(s):  
3D Printing ◽  
Medical Devices ◽  
Three Dimensional ◽  
Pharmaceutical Sciences ◽  
Three Dimensional Printing ◽  
Custom Made ◽  
High Degree ◽  
The Impact ◽  
Dimensional Printing ◽  
Shed Light

Three-dimensional (3D) printing is a unique technique that allows for a high degree of customisation in pharmacy, dentistry and in designing of medical devices. 3D printing satiates the increasing exigency for consumer personalisation in these fields as custom-made medicines catering to the patients’ requirements are novel advancements in drug therapy. Current research in 3D printing indicates towards reproducing an organ in the form of a chip; paving the way for more studies and opportunities to perfecting the existing technique. In addition, we will also attempt to shed light on the impact of 3D printing in the COVID-19 pandemic.

scholarly journals Three-dimensional printing for device selection in cardiology: Several key points should not be neglected

2016 ◽  
Author(s):  
Hongxing Luo ◽  
Zhongmin Wang
Keyword(s):  
3D Printing ◽  
Clinical Medicine ◽  
Three Dimensional ◽  
Three Dimensional Printing ◽  
Image Postprocessing ◽  
Key Points ◽  
Study Results ◽  
Recent Developments ◽  
3D Transesophageal Echocardiography ◽  
Dimensional Printing

We comment on the recent developments and problems of three-dimensional printing in cardiology. Since there are currently no standards or consensuses for 3D printing in clinical medicine and the technology is at its infancy in cardiology, it’s very important to detail the procedures to allow more similar studies to further our understandings of this novel technology. Most studies have employed computed tomography to obtain source data for 3D printing, the use of real-time 3D transesophageal echocardiography for data acquisition remains rare, so it would be very valuable and inspiring to detail the image postprocessing steps, or the reliability of the study results will be doubtful.

scholarly journals Comparison of Presurgical Dental Models Manufactured with Two Different Three-Dimensional Printing Techniques

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Marcin Metlerski ◽  
Katarzyna Grocholewicz ◽  
Aleksandra Jaroń ◽  
Mariusz Lipski ◽  
Grzegorz Trybek ◽  
...  
Keyword(s):  
3D Printing ◽  
Oral Surgery ◽  
Three Dimensional ◽  
Mean Deviation ◽  
Printing Technology ◽  
Three Dimensional Printing ◽  
Reference Models ◽  
3D Printing Technology ◽  
Dimensional Printing ◽  
Printing Time

Three-dimensional printing is a rapidly developing area of technology and manufacturing in the field of oral surgery. The aim of this study was comparison of presurgical models made by two different types of three-dimensional (3D) printing technology. Digital reference models were printed 10 times using fused deposition modelling (FDM) and digital light processing (DLP) techniques. All 3D printed models were scanned using a technical scanner. The trueness, linear measurements, and printing time were evaluated. The diagnostic models were compared with the reference models using linear and mean deviation for trueness measurements with computer software. Paired t-tests were performed to compare the two types of 3D printing technology. A P value < 0.05 was considered statistically significant. For FDM printing, all average distances between the reference points were smaller than the corresponding distances measured on the reference model. For the DLP models, the average distances in the three measurements were smaller than the original. Only one average distance measurement was greater. The mean deviation for trueness was 0.1775 mm for the FDM group and 0.0861 mm for the DLP group. Mean printing time for a single model was 517.6 minutes in FDM technology and 285.3 minutes in DLP. This study confirms that presurgical models manufactured with FDM and DLP technologies are usable in oral surgery. Our findings will facilitate clinical decision-making regarding the best 3D printing technology to use when planning a surgical procedure.

scholarly journals Three-Dimensional Printing: Custom-Made Implants for Craniomaxillofacial Reconstructive Surgery

2017 ◽  
Vol 10 (2) ◽  
pp. 089-098 ◽  
Author(s):  
Mariana Matias ◽  
Horácio Zenha ◽  
Horácio Costa
Keyword(s):  
3D Printing ◽  
Reconstructive Surgery ◽  
Three Dimensional ◽  
Tactile Feedback ◽  
Current Status ◽  
Printing Technology ◽  
Three Dimensional Printing ◽  
3D Printing Technology ◽  
Custom Made ◽  
The Aesthetic

Craniomaxillofacial reconstructive surgery is a challenging field. First it aims to restore primary functions and second to preserve craniofacial anatomical features like symmetry and harmony. Three-dimensional (3D) printed biomodels have been widely adopted in medical fields by providing tactile feedback and a superior appreciation of visuospatial relationship between anatomical structures. Craniomaxillofacial reconstructive surgery was one of the first areas to implement 3D printing technology in their practice. Biomodeling has been used in craniofacial reconstruction of traumatic injuries, congenital disorders, tumor removal, iatrogenic injuries (e.g., decompressive craniectomies), orthognathic surgery, and implantology. 3D printing has proven to improve and enable an optimization of preoperative planning, develop intraoperative guidance tools, reduce operative time, and significantly improve the biofunctional and the aesthetic outcome. This technology has also shown great potential in enriching the teaching of medical students and surgical residents. The aim of this review is to present the current status of 3D printing technology and its practical and innovative applications, specifically in craniomaxillofacial reconstructive surgery, illustrated with two clinical cases where the 3D printing technology was successfully used.

scholarly journals Low cost digital fabrication approach for thumb orthoses

2017 ◽  
Vol 23 (6) ◽  
pp. 1020-1031 ◽  
Author(s):  
Miguel Fernandez-Vicente ◽  
Ana Escario Chust ◽  
Andres Conejero
Keyword(s):  
3D Printing ◽  
Computer Aided Design ◽  
Low Cost ◽  
Three Dimensional ◽  
Recovery Process ◽  
Digital Fabrication ◽  
Cost Comparison ◽  
Content Type ◽  
Custom Made ◽  
The Impact

Purpose The purpose of this paper is to describe a novel design workflow for the digital fabrication of custom-made orthoses (CMIO). It is intended to provide an easier process for clinical practitioners and orthotic technicians alike. It further functions to reduce the dependency of the operators’ abilities and skills. Design/methodology/approach The technical assessment covers low-cost three-dimensional (3D) scanning, free computer-aided design (CAD) software, and desktop 3D printing and acetone vapour finishing. To analyse its viability, a cost comparison was carried out between the proposed workflow and the traditional CMIO manufacture method. Findings The results show that the proposed workflow is a technically feasible and cost-effective solution to improve upon the traditional process of design and manufacture of custom-made static trapeziometacarpal (TMC) orthoses. Further studies are needed for ensuring a clinically feasible approach and for estimating the efficacy of the method for the recovery process in patients. Social implications The feasibility of the process increases the impact of the study, as the great accessibility to this type of 3D printers makes the digital fabrication method easier to be adopted by operators. Originality/value Although some research has been conducted on digital fabrication of CMIO, few studies have investigated the use of desktop 3D printing in any systematic way. This study provides a first step in the exploration of a new design workflow using low-cost digital fabrication tools combined with non-manual finishing.

Manufacture of an Unmanned Aerial Vehicle (UAV) for Advanced Project Design Using 3D Printing Technology

2013 ◽  
Vol 397-400 ◽  
pp. 970-980 ◽  
Author(s):  
Noor A. Ahmed ◽  
J.R. Page
Keyword(s):  
3D Printing ◽  
Unmanned Aerial Vehicle ◽  
Three Dimensional ◽  
Small Scale ◽  
Project Design ◽  
Test Model ◽  
Printing Technology ◽  
Three Dimensional Printing ◽  
Aerial Vehicle ◽  
Dimensional Printing

The phenomenal growth in three-dimensional printing technology has the potential of ushering in the next wave of industrial revolution. As part of an advanced project design conducted at the Aerospace Engineering of the University of New South, the concept of a printable unmanned aerial vehicle was explored. A subsequent small scale test model was manufactured using three-dimensional printing technology for wind tunnel testing and validation. The exercise demonstrates the huge potential of such printing technology in future aircraft designs.Key words: 3D printing, design, manufacture, UAV

scholarly journals Current research in development of polycaprolactone filament for 3D bioprinting: a review

2021 ◽  
Vol 926 (1) ◽  
pp. 012080
Author(s):  
C Amni ◽  
Marwan ◽  
S Aprilia ◽  
E Indarti
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
Development Stage ◽  
Biological Properties ◽  
Fabrication Process ◽  
3D Bioprinting ◽  
Three Dimensional Printing ◽  
Further Development ◽  
Dimensional Printing ◽  
The Ideal

Abstract Three-dimensional printing (3DP) provides a fast and easy fabrication process without demanding post-processing. 3D-bioprinting is a special class in 3DP. Bio-printing is the process of accurately 3DP structural design using filament. 3D bio-printing technology is still in the development stage, its application in various engineering continues to increase, such as in tissue engineering. As a forming material in 3D printing, many types of commercial filaments have been developed. Filaments can be produced from either natural or synthetic biomaterials alone, or a combination of the two as a hybrid material. The ideal filament must have precise mechanical, rheological and biological properties. Polycaprolactone (PCL) is specifically developed and optimized for bio-printing of 3D structures. PCL is a strategy in 3D printing to better control interconnectivity and porosity spatially. Structural stability and less sensitive properties environmental conditions, such as temperature, humidity, etc make PCL as an ideal material for the FDM fabrication process. In this review, we provide an in-depth discussion of current research on PCL as a filament currently used for 3D bio-printing and outline some future perspectives in their further development.

scholarly journals Three-Dimensional Printing Strategies for Irregularly Shaped Cartilage Tissue Engineering: Current State and Challenges

2022 ◽  
Vol 9 ◽  
Author(s):  
Hui Wang ◽  
Zhonghan Wang ◽  
He Liu ◽  
Jiaqi Liu ◽  
Ronghang Li ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Cartilage Tissue ◽  
Future Research ◽  
Engineering Construction ◽  
Three Dimensional Printing ◽  
Current State ◽  
Dimensional Printing

Although there have been remarkable advances in cartilage tissue engineering, construction of irregularly shaped cartilage, including auricular, nasal, tracheal, and meniscus cartilages, remains challenging because of the difficulty in reproducing its precise structure and specific function. Among the advanced fabrication methods, three-dimensional (3D) printing technology offers great potential for achieving shape imitation and bionic performance in cartilage tissue engineering. This review discusses requirements for 3D printing of various irregularly shaped cartilage tissues, as well as selection of appropriate printing materials and seed cells. Current advances in 3D printing of irregularly shaped cartilage are also highlighted. Finally, developments in various types of cartilage tissue are described. This review is intended to provide guidance for future research in tissue engineering of irregularly shaped cartilage.

scholarly journals Effect of Three-dimensional Printing with Nanotubes on Impact Resistance

2019 ◽  
Author(s):  
Anne Schmitz
Keyword(s):  
Mechanical Properties ◽  
Lower Limb ◽  
Impact Resistance ◽  
Three Dimensional ◽  
Three Dimensional Printing ◽  
Impact Tester ◽  
The Impact ◽  
Dimensional Printing ◽  
Pendulum Impact ◽  
Pendulum Impact Tester

Abstract The types of biomedical devices that can be three-dimensional printed (3DP) is limited by the mechanical properties of the resulting materials. As a result, much research has focused on adding carbon nanotubes (CNT) to these photocurable polymers to make them stronger. However, there is little to no data on how CNTs affect the impact resistance of these polymers, an important property when designing and manufacturing lower limb prosthetics. The objective of this study was to expand the use of 3DP to prosthetics by testing the hypothesis that adding CNTs to a stereolithographic (SLA) photocurable resin will result in a cured polymer with increased impact resistance. Twenty-six total specimens: 13 with nanotubes and 13 without nanotubes, were printed on a Form2 SLA printer. Once all the specimens were printed, washed, and cured, the impact resistance was quantified using a pendulum impact tester in a notched Izod configuration. Contrary to the hypothesis, the specimens with SWCNTs (0.312 ± 0.036 ft*lb/in) had a significantly lower impact resistance compared to the non-SWCNT specimens (0.364 ± 0.055 ft*lb/in), U = 34.0, p = 0.004. This decreased impact resistance may be due to voids in the printed polymer around the aggregated nanotubes. Thus, SLA polymers still do not have the impact strength needed to be used for a full lower limb prosthetic.

scholarly journals Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review

2022 ◽  
Vol 14 (1) ◽  
pp. 32-39
Author(s):  
Sachit Anand ◽  
Nellai Krishnan ◽  
Prabudh Goel ◽  
Anjan Kumar Dhua ◽  
Vishesh Jain ◽  
...  
Keyword(s):  
Systematic Review ◽  
3D Printing ◽  
Solid Tumors ◽  
Surgical Planning ◽  
Three Dimensional ◽  
Current Evidence ◽  
Printing Technology ◽  
Three Dimensional Printing ◽  
3D Printed ◽  
Dimensional Printing

Background: In cases with solid tumors, preoperative radiological investigations provide valuable information on the anatomy of the tumor and the adjoining structures, thus helping in operative planning. However, due to a two-dimensional view in these investigations, a detailed spatial relationship is difficult to decipher. In contrast, three-dimensional (3D) printing technology provides a precise topographic view to perform safe surgical resections of these tumors. This systematic review aimed to summarize and analyze current evidence on the utility of 3D printing in pediatric extra-cranial solid tumors. Methods: The present study was registered on PROSPERO—international prospective register of systematic reviews (registration number: CRD42020206022). PubMed, Embase, SCOPUS, and Google Scholar databases were explored with appropriate search criteria to select the relevant studies. Data were extracted to study the bibliographic information of each article, the number of patients in each study, age of the patient(s), type of tumor, organ of involvement, application of 3D printing (surgical planning, training, and/or parental education). The details of 3D printing, such as type of imaging used, software details, printing technique, printing material, and cost were also synthesized. Results: Eight studies were finally included in the systematic review. Three-dimensional printing technology was used in thirty children with Wilms tumor (n = 13), neuroblastoma (n = 7), hepatic tumors (n = 8), retroperitoneal tumor (n = 1), and synovial sarcoma (n = 1). Among the included studies, the technology was utilized for preoperative surgical planning (five studies), improved understanding of the surgical anatomy of solid organs (two studies), and improving the parental understanding of the tumor and its management (one study). Computed tomography and magnetic resonance imaging were either performed alone or in combination for radiological evaluation in these children. Different types of printers and printing materials were used in the included studies. The cost of the 3D printed models and time involved (range 10 h to 4–5 days) were reported by two studies each. Conclusions: 3D printed models can be of great assistance to pediatric surgeons in understanding the spatial relationships of tumors with the adjacent anatomic structures. They also facilitate the understanding of families, improving doctor–patient communication.

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