Biomimetic Architecture Towards Bio Inspired Adaptive Envelopes: In Case of Plant Inspired Concept Generation

In recent decades, the value of architecture become more due to its importance for reducing detrimental effects on the environment and natural capital. To minimize the building's impact on the environment, architectural designs should be highly incorporated into the environment rather than behaving as a separate element focused on a single issue. To address this problem, different methods and design approaches have been introduced. However, exploring the natural solutions for survival can provide invaluable data which can address the human-caused problems. Throughout decades, nature has been survived and evolved. Biological solutions due to their adaptability and multi-functionality are great source of inspiration. This article with help of content analysis method aims to review the concept of biomimetic design in architecture. And proposes plant-inspired solutions for envelope design which can play significant role on buildings’ energy efficiency. Thus, the plant-inspired concepts to be integrated on adaptive envelopes were studied. And a framework for concept generation introduced. Furthermore, a case study on an existing building envelope in the Mediterranean climate region presented and two plant-inspired techniques proposed and conceptually applied.

A bio-inspired approach for boosting innovation in the separation technology sector

Because of its size, high segmentation within the global market and challenges driving its development, the separation technology sector could benefit from a bio-inspired approach to innovation to create more efficient and sustainable solutions. The potential for bio-inspired innovation is still largely untapped and Biologically-Inspired Design (BID) methods and tools are still largely underutilised, especially within the industry. A new BID method, called Guild-Based (GB) BID, is proposed to create a database of a large set of biological solutions – identified by a function – where biological information is structured to be more effective and usable within the industrial environment. A database for the separation technology sector has been set up and populated with 118 relevant biological solutions responding to the main function ‘to separate’. The database has been utilised to generate several clusters of solutions depending on the level of detail of the formulated problem. In particular, these include broad design principles of separation, taxonomies of biological solutions for specific separation problems and novel design concepts for two specific separation technologies (a desalination technology and an antibacterial surface). Furthermore, because of a large dataset of biological solutions, the possibility of determining the frequency of occurrence of specific separation strategies in nature can trigger reflections on the impact of existing separation technologies and taking decisions on future related R&D paths. More tests need to be conducted in the industrial environment; however, the results achieved so far indicate that the method proposed can indeed be instrumental to generating innovative ideas of interest to the separation technology sector.

Recent Progress in Electrochemical Immunosensors

Biosensors used for medical diagnosis work by analyzing physiological fluids. Antibodies have been frequently used as molecular recognition molecules for the specific binding of target analytes from complex biological solutions. Electrochemistry has been introduced for the measurement of quantitative signals from transducer-bound analytes for many reasons, including good sensitivity. Recently, numerous electrochemical immunosensors have been developed and various strategies have been proposed to detect biomarkers. In this paper, the recent progress in electrochemical immunosensors is reviewed. In particular, we focused on the immobilization methods using antibodies for voltammetric, amperometric, impedimetric, and electrochemiluminescent immunosensors.

Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights

Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of irradiation induces the degradation and the release of chemicals able to spoil the biological solutions. Surprisingly, there are no investigations on multi-layer films combining multi-technique and multi-method approaches to unveil the events occurring during γ-irradiation. Furthermore, our investigations are focuses on properties/events occurring at product, macromolecular, and molecular levels.

Biomimetics and Education in Europe: Challenges, Opportunities, and Variety

Biomimetics is an interdisciplinary field of science that deals with the analysis and systematic transfer of biological insights into technical applications. Moreover, the development of biomimetic products helps to improve our understanding of biological concept generators (reverse biomimetics). What does this mean for the education of kindergarten children, pupils, students, teachers, and others interested in biomimetics? The challenge of biomimetics is to have a solid knowledge base in the scientific disciplines involved and the competency to be open-minded enough to develop innovative solutions. This apparently contradictory combination ensures the transfer of knowledge from biology to engineering and vice versa on the basis of a common language that is perfectly understandable to everyone, e.g., the language of models, algorithms, and complete mathematical formulations. The opportunity within biomimetics is its ability to arouse student interest in technology via the fascination inherent in biological solutions and to awaken enthusiasm for living nature via the understanding of technology. Collaboration in working groups promotes professional, social, and personal skills. The variety of biomimetics is mirrored by the large number of educational modules developed with respect to existing biomimetic products and methods.

Pulsed 3.5 GHz high power microwaves irradiation on physiological solution and their biological evaluation on human cell lines

Microwave (MW) radiation is increasingly being used for several biological applications. Many investigations have focused on understanding the potential influences of pulsed MW irradiation on biological solutions. The current study aimed to investigate the effects of 3.5 GHz pulsed MW radiation-irradiated liquid solutions on the survival of human cancer and normal cells. Different physiological solutions such as phosphate buffer saline, deionized water, and Dulbecco’s modified Eagle medium (DMEM) for cell culture growth were irradiated with pulsed MW radiation (45 shots with the energy of 1 mJ/shot). We then evaluated physiological effects such as cell viability, metabolic activity, mitochondrial membrane potential, cell cycle, and cell death in cells treated with MW-irradiated biological solutions. As MW irradiation with power density ~ 12 kW/cm2 mainly induces reactive nitrogen oxygen species in deionized water, it altered the cell cycle, membrane potential, and cell death rates in U373MG cells due to its high electric field ~ 11 kV/cm in water. Interestingly, MW-irradiated cell culture medium and phosphate-buffered saline did not alter the cellular viability and metabolic energy of cancer and normal cells without affecting the expression of genes responsible for cell death. Taken together, MW-irradiated water can alter cellular physiology noticeably, whereas irradiated media and buffered saline solutions induce negligible or irrelevant changes that do not affect cellular health.

Bio-Separated and Gate-Free 2D MoS2 Biosensor Array for Ultrasensitive Detection of BRCA1

2D molybdenum disulfide (MoS2)-based thin film transistors are widely used in biosensing, and many efforts have been made to improve the detection limit and linear range. However, in addition to the complexity of device technology and biological modification, the compatibility of the physical device with biological solutions and device reusability have rarely been considered. Herein, we designed and synthesized an array of MoS2 by employing a simple-patterned chemical vapor deposition growth method and meanwhile exploited a one-step biomodification in a sensing pad based on DNA tetrahedron probes to form a bio-separated sensing part. This solves the signal interference, solution erosion, and instability of semiconductor-based biosensors after contacting biological solutions, and also allows physical devices to be reused. Furthermore, the gate-free detection structure that we first proposed for DNA (BRCA1) detection demonstrates ultrasensitive detection over a broad range of 1 fM to 1 μM with a good linear response of R2 = 0.98. Our findings provide a practical solution for high-performance, low-cost, biocompatible, reusable, and bio-separated biosensor platforms.