The influencing factors of academic professional mobility in colleges and universities are complex and diverse, and the intensity of each influencing factor has obvious characteristics of differentiation. However, scholars have few relevant studies based on the intensity of factors affecting the flow of academic professionals in colleges and universities. Therefore, this article aims to study and analyze the influence of different factors on the flow of academic professionals in different types of colleges and universities, which is of great significance for promoting the rational and orderly flow of academic professionals. This paper proposes a comprehensive application of multiple methods, such as questionnaire surveys and data statistics, based on ERG theory, based on the four types of universities and colleges: research-oriented, teaching research, teaching, and application. The influence intensity of the flow-influencing factors is comparatively studied. It clarified the differences in the influence of spiritual factors, economic factors, and social factors on the mobility of academic professionals in colleges and universities, established a mobility factor model, and put forward policy recommendations for colleges and universities to promote the rational and orderly mobility of academic professionals. A total of 2042 questionnaires on “Policy Improvement Factors Affecting the Flow of Academic Experts in Universities” were released, four academic experts of different levels were assigned to universities, and 1,561 were effectively searched. Among them, there were 336 research universities, 157 educational research universities, 404 educational universities, and 164 applied universities. The experimental results of this article show that the factors affecting the flow of academic professionals in universities include economic strength factor of 0.4945, social strength factor of 0.5456, and intellectual strength factor of 0.52. Therefore, the factors affecting the mobility of university scholars can be used in strategic research.