Anaximander thought water is a bad idea for a primary substance of the universe because it’s not neutral—it has an opposite, fire. And opposites destroy; they don’t generate one another. If everything in the universe were initially water, it would be impossible to have its opposite, fire, ever created because water destroys fire. Thus, quarks and leptons can’t be primary, for they have opposites, their antimatter versions, and as opposites, matter and antimatter annihilate, not generate, each other. Anaximander taught everything is generated from the apeiron: a timeless, neutral substance, encompassing the universe and constantly transforming into competing transient opposites, but with measure to preserve the cosmic justice—without absolute dominance by either opposite. In physics, it’s ubiquitous energy that’s constantly transforming into competing opposites—matter and antimatter—with measure. Curiously, however, matter (“water”) is more plentiful than antimatter (“fire”). Why? Nobody knows. Where’s the cosmic justice?