Comparative evaluation of analogue front-end designs for the CMS Inner Tracker at the High Luminosity LHC

The CMS Inner Tracker, made of silicon pixel modules, will be entirely replaced prior to the start of the High Luminosity LHC period. One of the crucial components of the new Inner Tracker system is the readout chip, being developed by the RD53 Collaboration, and in particular its analogue front-end, which receives the signal from the sensor and digitizes it. Three different analogue front-ends (Synchronous, Linear, and Differential) were designed and implemented in the RD53A demonstrator chip. A dedicated evaluation program was carried out to select the most suitable design to build a radiation tolerant pixel detector able to sustain high particle rates with high efficiency and a small fraction of spurious pixel hits. The test results showed that all three analogue front-ends presented strong points, but also limitations. The Differential front-end demonstrated very low noise, but the threshold tuning became problematic after irradiation. Moreover, a saturation in the preamplifier feedback loop affected the return of the signal to baseline and thus increased the dead time. The Synchronous front-end showed very good timing performance, but also higher noise. For the Linear front-end all of the parameters were within specification, although this design had the largest time walk. This limitation was addressed and mitigated in an improved design. The analysis of the advantages and disadvantages of the three front-ends in the context of the CMS Inner Tracker operation requirements led to the selection of the improved design Linear front-end for integration in the final CMS readout chip.

Unveiling the key factor for the phase reconstruction and exsolved metallic particle distribution in perovskites

To significantly increase the amount of exsolved particles, the complete phase reconstruction from simple perovskite to Ruddlesden-Popper (R-P) perovskite is greatly desirable. However, a comprehensive understanding of key parameters affecting the phase reconstruction to R-P perovskite is still unexplored. Herein, we propose the Gibbs free energy for oxygen vacancy formation in Pr0.5(Ba/Sr)0.5TO3-δ (T = Mn, Fe, Co, and Ni) as the important factor in determining the type of phase reconstruction. Furthermore, using in-situ temperature & environment-controlled X-ray diffraction measurements, we report the phase diagram and optimum ‘x’ range required for the complete phase reconstruction to R-P perovskite in Pr0.5Ba0.5-xSrxFeO3-δ system. Among the Pr0.5Ba0.5-xSrxFeO3-δ, (Pr0.5Ba0.2Sr0.3)2FeO4+δ – Fe metal demonstrates the smallest size of exsolved Fe metal particles when the phase reconstruction occurs under reducing condition. The exsolved nano-Fe metal particles exhibit high particle density and are well-distributed on the perovskite surface, showing great catalytic activity in fuel cell and syngas production.

Numerical simulation flow dynamics of an intracranial aneurysm

BACKGROUND: Computational fluid dynamics provides a new method for the study of the blood flow characteristics of the formation and development of intracranial aneurysms. OBJECTIVE: To compare blood flow characteristics between the healthy internal carotid artery and normal intracranial aneurysms. METHODS: The internal carotid arteries were simulated to obtain hemodynamic parameters in one patient. RESULTS: The internal carotid artery associated with aneurysm presents low wall shear stress, high oscillatory shear index, and high particle retention time compared with the normal internal carotid artery. CONCLUSIONS: There are differences in blood flow between the normal internal carotid artery and intracranial aneurysm. The vortex of the aneurysm will produce turbulence, indicating that it is unstable, which results in the growth and rupture of the aneurysm.

Optimization of Compaction Quality Control in the Core of Random Fillings within Linear Infrastructures: Application to Metamorphic Slate Fillings

The construction of random fillings from the excavation of medium hardness rocks, with high particle sizes, presents limitations in compaction control. This research applies new control techniques with revised test procedures in the construction of the random fillings core, which constitutes the main part of the embankment, with the bigger volume and provides the geotechnical stability to the infrastructure. The maximum thickness over each of the compacted layers researched that made up the random fillings was 800 mm. As there are many types of rocks, this research is applied to metamorphic slates. Quality control was carried out by applying new research associated with the revision of wheel impression test, topographic settlements, and plate bearing test (PBT). Thus, new test procedures are established, defining efficient thresholds. Comparisons make it possible to choose representative tests, avoiding duplication. The optimization of control reduces inspection times, ensuring quality adapted to the high construction efficiency of diggings. Traditionally, rocks were rejected due to their maximum size, underutilizing the use of high-quality materials. Promoting their utilization implies a better use of resources, and therefore, a higher environmental efficiency. A statistical analysis of the core of 16 slate random fillings was carried out, with a total of 2250 in situ determination of density and moisture content, 75 wheel impression tests, 75 topographic settlement controls, and 75 PBT. The strong associations found between different tests allowed to simplify the quality control.

Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion

Granular hydrogels have emerged as a new class of injectable and porous biomaterials that improve integration with host tissue when compared to solid hydrogels. Granular hydrogels are typically prepared using spherical particles and this study considers whether particle shape (i.e., isotropic spheres versus anisotropic rods) influences granular hydrogel properties and cellular invasion. Simulations predict that anisotropic rods influence pore shape and interconnectivity, as well as bead transport through granular assemblies. Photocrosslinkable norbornene- modified hyaluronic acid is used to produce spherical and rod-shaped particles using microfluidic droplet generators and formed into shear-thinning and self-healing granular hydrogels at low and high particle packing. Rod-shaped particles form granular hydrogels that have anisotropic and interconnected pores, with pore number and size, storage moduli, and extrusion forces influenced by particle shape and packing. Robust in vitro sprouting of endothelial cells from embedded cellular spheroids is observed with rod-shaped particles, including higher sprouting densities and sprout lengths when compared to hydrogels with spherical particles. Cellular invasion into granular hydrogels when injected subcutaneously in vivo is significantly greater with rod-shaped particles, whereas a gradient of cellularity is observed with spherical particles. Overall, this work demonstrates potentially superior functional properties of granular hydrogels with rod-shaped particles for tissue repair.

Nuclear Processes in Dark Interstellar Matter of H(0) Decrease the Hope of Migrating to Exoplanets

It is still generally assumed that interstellar travel will be possible after purely technical development and thus that mankind can move to some suitable exoplanet when needed. However, recent research indicates this not to be the case, since interstellar space is filled with enough ultradense hydrogen H(0) as stable condensed dark matter (Holmlid, Astrophysical Journal 2018) to make interstellar space travel at the required and technically feasible relativistic velocities (Holmlid et al, Acta Astronautica 2020) almost impossible. H(0) can be observed to exist in space from the so-called extended red emission (ERE) features observed in space. A recent review (Holmlid et al., Physica Scripta 2019) describes the properties of H(0). H(0) gives nuclear processes emitting kaons and other particles, with kinetic energies even above 100 MeV after induction for example by fast particle (spaceship) impact. These high particle energies give radiative temperatures of 12000 K in collisions against a solid surface and will rapidly destroy any spaceship structure moving into the H(0) clouds at relativistic velocity. The importance of preserving our ecosystem is pointed out, since travel to suitable exoplanets may be impossible. The possibilities of instead clearing interstellar space from H(0) are discussed, eventually providing tunnels suitable for relativistic interstellar transport. Finding regions with low intensity of ERE could even be a way to identify space-cleaning activities and thus to locate earlier space-travelling civilizations.

Modifications for Optimization the Compaction Quality Control in Core Slate Random Filling Embankments for Linear Infrastructures

The construction of random fillings from the excavation of medium hardness rocks, with high particle sizes, presents limitations in compaction control. This research applies new control techniques with revised test procedures in the construction of the random fillings core, which constitutes the main part of the embankment, with the bigger volume and provides the geotechnical stability to the infrastructure. The maximum layer thickness researched was 800mm. As there are many types of rocks, this research is applied to metamorphic slates. Quality control has been carried out by applying new research associated with the revision of wheel impression test, topographic settlements and plate bearing test (PBT). A statistical analysis of the core of 16 slate random fillings has been carried out, with a total of 2250 in situ determination of density and moisture content, 75 wheel impression tests, 75 topographic settlement control and 75 PBT. The strong associations found between different tests have allowed to simplify the quality control.

Noxic effects of polystyrene microparticles on murine macrophages and epithelial cells

Microplastic (MP) contamination has been identified as an ecological problem with an increasing impact on everyday life. Yet, possible effects of MP at the cellular level are still poorly understood. Here, the interaction of murine macrophages (J774A.1, ImKC) and epithelial cells (STC-1, BNL CL.2) with well-characterized poly(styrene) MP particles (MPP) of varying sizes (0.2–6.0 µm) was studied. Macrophages are expected to actively engulf particles which could be confirmed in this study, while epithelial cells are found in tissues with direct contact with ingested or inhaled MPP. Here, the epithelial cells from both investigated cell lines did not ingest MPP in significant numbers. Concomitantly, no cytotoxic effects nor any influence on cellular proliferation were observed. Cells from the two macrophage cell lines showed high ingestion of MPP of all sizes, but cytotoxic effects were observed only for one of them (ImKC) and only at MPP concentrations above 250 µg/mL. Indications of cellular stress as well as effects on cell proliferation were observed for cell populations with high particle cell interactions.

Effect of Filler Morphology on the Electrical and Thermal Conductivity of PP/Carbon-Based Nanocomposites

In this paper, we studied the effect of different carbon-based nanostructures on the electrical and mechanical properties of polypropylene (PP) nanocomposites. Multi-walled carbon nanotubes (MWCNT), expanded graphite (EG), and two different carbon black nanoparticles (CB) have been dispersed at several weight contents in the polymer matrix through a melt extrusion process. The produced nanocomposites have been used to obtain samples for the characterization by injection molding. The dispersion of the nanoparticles in the matrix has been evaluated by scanning electron microscopy (SEM) analysis. The electrical characterization has been performed both in DC and in AC configuration. The mechanical properties have been evaluated with both tensile test and impact strength (Izod). The thermal conductivity has been also evaluated. As a result, MWCNTs are the nanoadditive with the lowest electrical percolation threshold. This allows MWCNT nanocomposite to drastically change the electrical behavior without a significant embrittlement observed with the other nanoadditives. However, CB with the lowest surface area allows the highest conductivity, even though at a high particle content. EG has a limited effect on electrical properties, but it is the only one with a significant effect on thermal conductivity.

Validation of a two-layer depth-averaged model by comparison with an experimental dilute stratified pyroclastic density current

Numerical results of a two-layer depth-averaged model of pyroclastic density currents (PDCs) were compared with an experimental PDC generated at the international eruption simulator facility (the Pyroclastic flow Eruption Large-scale Experiment; PELE) to establish a minimal dynamical model of PDCs with stratification of particle concentrations. In the present two-layer model, the stratification in PDCs is modeled as a voluminous dilute turbulent suspension layer with low particle volume fractions (<10-2) and a thin basal bedload layer with high particle volume fractions (~10-2) on the basis of the source condition in the experiment. Numerical results for the dilute layer quantitatively reproduce the time evolutions of the front position and body thickness of the dilute part in the experimental PDC. The numerical results of the bedload thickness and deposit mass depend on an assumed value of mean deposition speed at the bottom of the bedload (D). We show that the thicknesses of bedload and deposit in the simulations agree well with the experimental data, when D is set to about 3.5 x 10-4 m/s. This value of the deposition speed is two orders of magnitude smaller than that predicted by a hindered-settling model. The small value of D suggests that the erosion process accompanied by saltating/rolling of particles plays a role in the sedimentation in the bedload.