Effect of Nano Fertilizers and Its Applying Methods on Growth Parameters of Senna (Cassia Angustifolia) Seedling Plant

The experiment was carried out at Plant Production Department, Agricultural Technical College, Mosul, Iraq at spring 2020 to investigate the effect of two Nano fertilizers kind (K 27%and Complex fertilizer Cu 1%, S 13%, Zn 11.5 %, Mn 6.5%, Fe7.5%, and Citric Acid 3.5 %.)and control (zero fertilizer). With three applying methods(spraying, soil addition, spraying + soil addition) on Senna seedlings. The treatments were layout in factorial experiment in RCBD Design with three replicates. The results showed that adding nano fertilizers by Spraying+ Soil Addition increase significantly plant length, number of leaves per plant, Stem diameter, Chlorophyll content (SPAD), fresh and dry weight of vegetative growth and roots. Also applying Complex Nano fertilizer increase significantly all the parameters(plant length, number of leaves per plant, Stem diameter, Chlorophyll content (SPAD), fresh and dry weight of vegetative growth and roots. compared with control and the increasing percentage were(62.12, 28.22,123.37, 19.19, 197.95, 154.48, 261.64, 114.26%)for the parameters respectively. The interaction treatments between nano fertilizers an applying methods show a significant effect for all the parameters.

Herbal Medicine for the Management of Laxative Activity

: Constipation is one of the most common and prevalent chronic gastrointestinal conditions across the globe that is treated or managed through various methods. Laxatives are used for the treatment or management of chronic/acute constipation. But due to the adverse effects associated with these laxatives, herbal foods should be considered as alternative therapies for constipation. In this review, the laxative potential of plant-based medicines used for constipation were discussed. Constipation may be caused by various factors such as lifestyle, particular food habits, pregnancy and even due to some medication. Chronic constipation is responsible for different health issues. Pharmacological and non-pharmacological paradigms are applied for the treatment or management of constipation. In the pharmacological way of treatment, medicinal plants have a key role, because of their fibrous nature. Numerous plants such as Prunus persica (Rosaceae), Cyamopsis tetragonolobus (Leguminosae), Citrus sinensis (Rutaceae), Planta goovata (Plantaginaceae), Rheum emodi (Polygonaceae), Cassia auriculata (Caesalpinacea), Ricinus communis (Euphorbiaceae), Croton tiglium (Euphorbiaceae), Aloe barbadensis (Liliaceae), Mareya micrantha (Euphorbiaceae), Euphorbia thymifolia (Euphorbiaceae), Cascara sagrada (Rhamnaceae), Cassia angustifolia (Fabaceae) have laxative activity. Medicinal plants possess a significant laxative potential and support their folklore therefore, further, well-designed clinical-based studies are required to prove and improve the efficacy of herbal medicine for constipation. The present review showed that herbs laxative effect in various in-vivo/ in-vitro models.

Outbreak of Catopsilia pyranthe L. on Senna (Cassia angustifolia Vahl) and Migration in Western Arid Region of India

Background: Cassia angustifolia Vahl, senna, known for medicinal properties belongs to family fabacea is a hardy plant, suitable for saline and rainfed conditions serving as a host for caterpillars of Catopsilia pyranthe L. butterflies suffering up to 90 per cent defoliation. An attempt was made to record butterfly migrations due to an outbreak of the lepidopteron pest on senna which is the first report on butterfly migration in western arid region.Methods: Surveys made in different districts for accurate quantification of butterflies passing within 5 minute through a 10 meter wide strip. For diurnal pattern, observations were taken on hourly basis. Correlation of butterfly density with weather parameters was worked out.Result: Migration was mainly in South West direction in a steady line connecting Jaisalmer, Jodhpur, Pali, Sirohi and Ajmer. The highest density (1360 butterflies/10m/5 minute) accounting for 16,320.0 butterflies/10m/hour and 97,920.0 butterflies/10m/day recorded in Keru (Jodhpur) representing bell shape curve of diurnal movement with a maximum activity between 12.00 noon and 1.00 PM.

Structure-based assortment of herbal analogues against spike protein to restrict COVID-19 entry through hACE2 receptor: An in-silico approach

On-going global pandemic COVID-19 has spread all over the world and has led to more than 1.97 million deaths till date. Natural compounds may be useful to protecting health in this perilous condition. Mechanism of shuttle entry of SARS-COV-2 virus is by interaction with viral spike protein with human angiotensin-converting enzyme-2 (ACE-2) receptor. To explore potential natural therapeutics, 213 important phytochemi-cals of nine medicinal plants Aconitum heterophyllum, Cassia angustifolia, Cymbopogon flexuosus, Cymbopogon martinii, Nux vomica, Phyllanthus urinaria, Swertia chirayita, Justicia adhatoda, Vetiveria zizanioides were selected for in-silico molecular docking against the spike protein of SARS-COV-2 and compared with recently prescribed drug chloroquine, ramdesivir, lopinavir and hydroxychloroquine. Results revealed that rhamnocitrin of P. urinaria, 1,5-dihydroxy-3,8-dimethoxyxanthone of S. chirayita and laevojunenol of V. zizanioides potentially binds with the receptor binding site of SARS-COV-2 spike glycoprotein and more robustly destabilized the RBD-ACE-2 binding over chloroquine, ramdesivir, lopinavir and hydroxychloroquine. It was also found that laevojunenol, rhamnocitrin, and 1,5-dihydroxy-3,8-dimethoxyxanthone qualified the criteria for drug-likeness as per Lipinski rule. After attachment of the selected phytochemical with the spike protein the affinity of the later towards ACE-2 was minimized and the effect of 1,5-dihydroxy-3,8-dimethoxyxanthone and laevojunenol was superior. Hence, rhamnocitrin of P. urinaria, 1,5-dihydroxy-3,8-dimethoxyxanthone of S. chirayita and laevojunenol of V. zizanioides, are potential therapeutic molecules for SARS-COV-2, which upon binding with spike protein changes the affinity of the spike towards ACE-2 and therefore restrict the entry of the virus into a human cell. Subsequent clinical validation is needed to confirm these phytochemicals as drugs to combat COVID-19.