Osteogenic Differentiation of Mesenchymal Stem Cells via Curcumin-Containing Nanoscaffolds

The diverse pleiotropic pharmacological effects of curcumin nanoformulations have turned it into an attractive natural compound in different health-related problems. A great body of evidence has shown the impact of curcumin and its nanoformulations on the differentiation of stem cells. The current review highlights cellular and molecular mechanisms connected with the osteogenic differentiation of mesenchymal stem cells (MSCs) in the scaffolds benefiting from the presence of nanocurcumin pointing toward the role of inhibitory or stimulant signal transduction pathways in detail. Moreover, the effects of different concentrations as well as the structural modifications of curcumin on the differentiation of MSCs have been addressed.

THE GREAT BODY OF SOCIETY: IS THE NINTH CENTURY RETURNING?

The author of the article puts a question about the limits of the 20th century individualism. He expresses a hypothesis about the cyclic nature of the cultural and political theory. In particular, he draws attention to the rhythm of changes of the hedonistic and ascetic ep- ochs, spiritualist and materialist epochs, individualist and holist epochs. The author ana- lyzes holistic doctrines of the 19th century: philosophies of Fabre d’Olivet, Auguste Comte, Pierre Leroux. Although today almost forgotten, the ideas of these authors can be revived again in the 21st century, he says. Based upon the analysis of the 19th century holism which the author did in his book Liquid ideologies, the author makes a hypothesis that the 21st century is becoming much less individualistic and much less materialistic than the 20th century. The metaphors of the “collective body” and “absolute spirit” are coming back in the 21st century, in the new form of the digital reality.

„Bhagavad-Gītā, and the Universal Wisdom of Hinduism”

The brief episode represented by the Bhagavad-Gītā, entrenched in the great body of the epic Hindu poem Mahābhārata, is revealing for the long lasting intellectual and spiritual effort made by the enlightened Indian philosophers in order to over-pass the ritual and social constraints put in place by the Veda, during the early period of the Hindu tradition. By focusing on the dialogue between a valiant knight and the earthly incarnation of God himself, a perennial wisdom is to be noticed. This is a promise for salvation from fear and death for all who dare to follow their duty, by offering them other ways of attending the Supreme. The self-sacrifice, the renunciation to all ego and the pure love for the Divine represent sacrifices that equal those offered by Hindu priests. By this, every single individual is meant to finally embrace freedom and eternity.

The Role of Written Corrective Feedback in EFL Writing

There is a great body of literature that indicates that writing is the most difficult language skill in language learning. Students often find it challenging to write a coherent, well thought and well accurate piece of writing because of the various aspects (organization, content, grammar, syntax, word choice) they need to satisfy while writing. For teachers of writing, what matters is not students’ mastery of all these aspects at once, but their ability to write a good piece of writing. This aim is really disregarded once the produced paper receives little or no feedback on students’ writing. Therefore, the proposed paper aims at outlining the different strategies and types of written corrective feedback that English foreign language (EFL) teachers employ to respond to students’ writings, focusing on the definitions, characteristics, advantages and limitations of each strategy and type. Suggestive dimensions of feedback provision and useful tips on implementing good feedback are also addressed.

Brachylaima spp. (Trematoda) parasitizing Cornu aspersum (Gastropoda) in France with potential risk of human consumption

The edible land snail Cornu aspersum, native to the Mediterranean coastlines of North Africa, is widely distributed on most continents and often invasive in areas where introduction is recent. This species could contribute to the geographic spread of parasites as demonstrated for Brachylaima spp. These cosmopolitan trematodes may represent a threat to human health, like in Australia where Brachylaima cribbi infects humans. In this study, we demonstrate for the first time the occurrence of Brachylaima spp. in two French populations of C. aspersum, Thorigné-Fouillard (Ille-et-Vilaine), and Arçais (Deux-Sèvres), with an overall prevalence of 10.4% (Thorigné-Fouillard) and 73.3% (Arçais), respectively and a metacercarial intensity on average three times higher in Thorigné-Fouillard (37) than in Arçais (11). Cornu aspersum may act as a first and second intermediate host, as demonstrated in Arçais. The morphometrics of metacercariae, particularly the great body length about 2 mm, discriminate our Brachylaima species from those already described in C. aspersum (B. cribbi in Australia, and B. aspersae, B. llobregatensis and B. mascomai in Europe). Molecular analysis, based on 28S and COI, suggests the occurrence of two species in our study, one of which is probably Brachylaima mesostoma, an intestinal parasite of passeriform birds described in Central Europe. We underline the need for further research to identify species of Brachylaima in France and measure the health hazard of consuming field-collected snails.

DOCUMENT ASPECTS OF THE ORGANISATION’S PERSONNEL MANAGEMENT

In the system of personnel management the questions of personnel office-work and docu-ment circulation are especially urgent. It is stipulated by the fact that the employees of personnel department have to work with great body of information and observe legislation requirements, local statutory acts, and etc. The article contains the aspects of standard-legal base in document per-sonnel activity of the organization, feature of personnel expert work in the in system of personnel management.

Education of Native Hawaiian Students

The purpose of this literature review is to provide an overview of Hawaiian education, its history, sources, and players. A certain narrative emerges through this review about what happens when conventional Western education systems are confronted by educational leadership powered by a distinctly indigenous culture, language, and knowledge system with its own epistemologies, reasoning, and logic. The narrative highlights the champions that have advocated for seeing Native Hawaiian knowledge systems as a pathway to educational transformation. Through this struggle, the relationships built over time have begun to produce systemic change. Thinking and learning in Native Hawaiian ways and in ʻōlelo Hawaiʻi (Hawaiian language) are slowly being integrated into the fabric of Hawaii’s pre-Kindergarten to Grade 12 schools and post-secondary institutions. Yet, as the millennium progresses, Native Hawaiians continue to be among the most marginalized populations in Hawaiʻi, indicating there is still much work ahead. The scholarship presented in this review traces a path of progress rooted in the great body and depth of Native Hawaiian knowledge. Admittedly, as collector-authors of this review, it was not possible to include a complete inventory of research and scholarship. Instead, we offer a select overview of an expanding field of knowledge generated by Native Hawaiian scholars and their allies, positioned here as a critical foundation upon which we continue to build. We begin with a set of references from a Native Hawaiian worldview that anchor educational approaches in our communities in the 21st century. Several sections on education in historical and social context follow, in addition to resources exploring pedagogy, praxis, culture-based education, research methodologies, and assessment. Also included are online sources and several university and legacy publishing organizations that produce resources in Hawaiian education.

Agustín Lorenzo: Beloved Bandit of History and Folklore

Agustín Lorenzo was a prototypical social bandit, according to Eric Hobsbawm’s definition in his studies of that phenomenon. As a bandit from south central Mexico believed to have lived between the 18th and 19th centuries, the exploits of Agustín Lorenzo have been recounted in myriad ways: myths, legends, loas, corridos, films, carnival representations, among others. Lorenzo is said to have stolen from the rich to give to the poor, swearing to avenge his grandfather’s mistreatment at the hands of his employer, the local landowner. To achieve his mission, the story goes, Lorenzo made a pact with the devil, to obtain supernatural powers. The attributes of this bandit undoubtedly place him in the same category as the great body of stories about banditry that have survived for centuries around the world, particularly considering their shared essence: a desire for justice. In the case of Agustín Lorenzo, it is possible to disentangle the universal principles Hobsbawm established regarding the phenomenon of social banditry from the local context in which this particular myth lives on. Hence, to analyze the myth of Agustín Lorenzo, it is essential to explore the narratives and meanings of the cosmogony of the Nahua peoples of south-central Mexico.

The growth of local white muscovy growth during starter and grower period

<p>Livestock animals with relatively fast growth and great body weight are potential as a producer of meat. In Indonesia, the local muscovy, especially the feathered white is one of the meat-producing livestock. However, an analysis of the growth on local white muscovy is still rarely done. Therefore, the purpose of this study was to determine the point of inflection as growth variables, thus simplifying the preparation of development programs of local white muscovy. A total of 168 of the local unsex white muscovy were examined for their growth since the DOD until 112 days of age. The data of growth i.e. body weight individually examined in every two weeks. The data were analyzed using Gompertz model. The result obtained was the growth equation of local white Muscovy based on the model of Gompertz: Y=2591.3*exp (-3.8636*exp-0.0272*t). Based on these equations, the point of inflection of the local white muscovy occurred at the age of 50 days with a weight of 953.29 g. The maximum body weight gain achieved was 2591.30 g. It is conclude that the growth of local white muscovy was relatively slow, but the body weight was very heavy.</p>