Dental Implants with Electrochemical Nanopattern Formation to Increase Osseointegration.

Nowadays, The coming acceleration of global population ageing. When people get older, the importance of implants is emphasized. Dental implants have a crucial effect on life satisfaction. Many techniques have already been developed it. However, those still required many procedures. Shin et al suggested the new model based on MA. The electrochemical nanopattern formation (ENF) model takes out lots of steps when it is made. It is very simple because it only removes TiO2 NT layers. Interestingly, we investigated many studies, this simple model did not distinguish the other commercial models. Surface modification by ENF process improved the osteogenic differentiation in cells. It did not limit the cells. In vivo study, ENF also promoted the bone to implant connectivity. The ENF technique used for the new substitute.

UVB Radiation and Selected Tryptophan-Derived AhR Ligands—Potential Biological Interactions in Melanoma Cells

Excessive UV exposure is considered the major environmental factor in melanoma progression. Human skin is constantly exposed to selected tryptophan-derived aryl hydrocarbon receptor (AhR) ligands, including kynurenine (KYN) and kynurenic acid (KYNA), as they are endogenously produced and present in various tissues and body fluids. Importantly, recent studies confirmed the biological activity of KYN and KYNA toward melanoma cells in vitro. Thus, in this study, the potential biological interactions between UVB and tryptophan metabolites KYN and KYNA were studied in melanoma A375, SK-MEL-3, and RPMI-7951 cells. It was shown that UVB enhanced the antiproliferative activity of KYN and KYNA in melanoma cells. Importantly, selected tryptophan-derived AhR ligands did not affect the invasiveness of A375 and RPMI-7951 cells; however, the stimulatory effect was observed in SK-MEL-3 cells exposed to UVB. Thus, the effect of tryptophan metabolites on metabolic activity, cell cycle regulation, and cell death in SK-MEL-3 cells exposed to UVB was assessed. In conclusion, taking into account that both UVB radiation and tryptophan-derived AhR ligands may have a crucial effect on skin cancer formation and progression, these results may have a significant impact, revealing the potential biological interactions in melanoma cells in vitro.

Beer mats make bad frisbees

In this article we show why flying and rotating beer mats, CDs, or other flat disks will eventually flip in the air and end up flying with backspin, thus, making them unusable as frisbees. The crucial effect responsible for the flipping is found to be the lift attacking not in the center of mass but slightly offset to the forward edge. This induces a torque leading to a precession towards backspin orientation. An effective theory is developed providing an approximate solution for the disk’s trajectory with a minimal set of parameters. Our theoretical results are confronted with experimental results obtained using a beer mat shooting apparatus and a high speed camera. Very good agreement is found.

Investigation of the Preschool Teacher Candidates’ Philosophical Views on the Nature of Mathematics

Teachers’ views on the nature of maths have a crucial effect on their interactions with children, their choice of method and technique to be used while preparing the curriculum, their decision on the type and frequency of activities to be applied, their behaviors in the classroom, children’s attitudes towards maths and their achievement. With this research, it is aimed to examine teacher candidates’ philosophical views on the nature of maths. The research is in relational scanning model. “The Scale of Philosophical Thoughts on the Nature of Mathematics” was implemented to 141 pre-school teacher candidates studying in 2019-2020, which constitute the sample of the study. As a result of the analysis, it has been found that 52.5% of teacher candidates have an absolutist view, the views of female and male teacher candidates support each other and there is a significant difference between the grade level in they study.

Game Theory-Based Minimization of the Ostracism Risk in Construction Companies

Strategic and managemerial decision-making in an organization can have a crucial effect for the whole entity; however, it rarely involves the organization’s employees evenly at the different organizational levels. The result is—what is addressed in this paper as—the ostracism risk, namely the risk accruing from the lack of satisfaction of underprivileged employees’ groups during the decision-making process. The ostracism risk could jeopardize the organization’s integrity and therefore requires effective treatment. This paper aims at verifying a conceptual approach, which is proposed as a methodology for assessing the probability of organizational cooperation when deciding under risk, thus minimizing ostracism risk. The proposed approach is based on organizational and human resources management (HRM) theories and is contextualized for construction through the understanding of systems theory. The proposed methodology presents a potential modelling via game theory of a medium-sized construction company that is organized according to Mintzberg’s organizational model. The utilization of the bounded Pareto distribution is presented as an approach of the model’s probabilistic processing, and the potential for estimating the probabilities to adopt a favorable cooperational decision is verified. The paper concludes with the reference to the next steps required for the methodology’s validation and further improvement.

Tobacco Root Endophytic Arthrobacter Harbors Genomic Features Enabling the Catabolism of Host-Specific Plant Specialized Metabolites

Host secondary metabolites have a crucial effect on the taxonomic composition of its associated microbiota. It is estimated that a single plant species produces hundreds of secondary metabolites; however, whether different classes of metabolites have distinctive or common roles in the microbiota assembly remains unclear.

High-Temperature Oxidation of Cr-Coated Resistance Upset Welds Made from E110 Alloy

The resistance upset welds (RUW) made from E110 alloy without and with Cr coatings were oxidized in air atmosphere at 1100 °C for 2, 10 and 30 min. The cross-section microstructure, elemental composition and hardness were studied before and after oxidation using optical and scanning electron microscopy, and indentations in welding region. The RUW welding does not noticeably change oxidation kinetics of E110 alloy. The most crucial effect has surface non-regularities formed after welding, which prevent uniform coating deposition on full surface of welded cladding tube and end plug. Cr coating deposition can strongly reduce oxidation of welded E110 alloy, while additional post-processing treatment should be applied to improve surface morphology after RUW welding. Several suggestions favorable to development of ATF Zr-based claddings using Cr coating deposition on welded nuclear rods were discussed.

PUBLIC MANAGEMENT OF INNOVATIONS IN THE SOCIO-HUMANITARIAN SPHERE: CHALLENGES AND WAYS TO OVERCOME

EU integration and globalization trends require new mechanisms and methods of regulating economic processes to transform Ukraine into an economically developed powerful state. Innovation is an integral part of any production cycle, but to achieve better results, innovation processes and relationships in the creation and implementation of innovative technologies in the national economy require active participation and great attention from the state. The main emphasis of such attention should be focused on organizational, legal and institutional support of innovation, which requires solving a vast number of problems of intensive development. The end of the twentieth century was a period of spreading ideas about the need to change the paradigm of public administration. Scientists began to realize the need to move to a new model of public administration based on strengthening the social nature of government. The change in approach implies an essential change in the state's role: from the producer of public goods to the regulator of market processes. During the implementation of this model, the most crucial effect is possible if the principles of openness, innovation, decentralization, and a combination of market and state regulation, individual freedom and new forms of individual and collective responsibility.