In this chapter on neurosurgery and anaesthesia, the authors give clear guidance for the management of time critical brain and neurological conditions, including raised intracerebral pressure, severe head injury, subarachnoid and intracerebral haemorrhage, sodium disturbances, venous air embolism, acute spinal cord injury, spinal shock, autonomic dysreflexia, dystonic reactions, and status epilepticus. In addition, the definitions, presentation, management strategies, investigations, risk factors, exclusions and causes, and any special considerations for each potential neurosurgical and neurologically related situation are given. Lists of up-to-date online resources and further reading are also provided here, offering invaluable know-how to encourage the reader to broaden their knowledge.