Noninvasive Transfontanelle Monitoring of the Intracerebral Pressure in Comparison With an Invasive Intradural Intracranial Pressure Device: A Prospective Study

2017 ◽  
Vol 13 (5) ◽  
pp. 609-613 ◽  
Author(s):  
Bedjan Behmanesh ◽  
Marco Bartels ◽  
Florian Gessler ◽  
Natalie Filmann ◽  
Volker Seifert ◽  
...  
Keyword(s):  
Intracranial Pressure ◽  
Correlation Analysis ◽  
Correlation Coefficient ◽  
External Ventricular Drain ◽  
Method Comparison ◽  
Icp Monitoring ◽  
Validity And Reliability ◽  
Noninvasive Technique ◽  
Monitoring Method ◽  
Intracerebral Pressure

Abstract BACKGROUND: We previously introduced a novel noninvasive technique of intracranial pressure (ICP) monitoring in children with open fontanelles. OBJECTIVE: To compare the ICP obtained by our new technique to the ICP derived from an intradurally implanted ICP measurement device (external ventricular drain, subdural ICP device). METHODS: Children with open fontanelles and need of intracranial monitoring were included in this study. A standard ICP probe was placed upon the frontal fontanelle and data were compared with the values recorded by an already invasively implanted subdural ICP technique. The 2 methods of ICP measurement were evaluated using the correlation coefficient, Bland and Altman method and method comparison by Carstensen. RESULTS: Five children under the age of 1 year with an open frontal fontanelle were included in this study. Three were male and 2 were female. Mean age was 7 months. A total of 139 pairs of measurements were assessed. Mean transfontanelle ICP was 7.6 mm Hg. Mean ICP measured subdurally was 5.4 mm Hg. The correlation analysis showed a correlation coefficient of 0.7. The Bland-Altman plot revealed a good accuracy of the new method with >95% of the values within the limits of agreement. An additional method comparison analysis confirmed the finding of accurate ICP measurements between both applied methods. CONCLUSION: The noninvasive transfontanelle ICP monitoring method displayed a high validity and reliability as proven by correlation analysis. This novel technique might therefore be an interesting and promising tool for noninvasive ICP monitoring in children. But further research is necessary to evaluate the accuracy of this technique in children with elevated ICP.

Surgical Treatment of Raised Intracranial Pressure

Neurotrauma ◽  
2019 ◽  
pp. 9-16
Author(s):  
Mohamed A. Zaazoue ◽  
Richard B. Rodgers
Keyword(s):  
Emergency Department ◽  
Intracranial Pressure ◽  
External Ventricular Drain ◽  
Altered Mental Status ◽  
Management Plan ◽  
Raised Intracranial Pressure ◽  
Icp Monitoring ◽  
Surgical Interventions ◽  
Head Ct ◽  
Medical Interventions

Traumatic brain injury (TBI) is a common problem encountered in the emergency department, and neurosurgeons are typically involved early in the management. Prompt physical examination and head CT are crucial to assess TBI patients and determine their management plan. Intracranial pressure (ICP) monitoring is indicated for patients with altered mental status and abnormal imaging. ICP management is a tiered approach, with early tiers involving nonsurgical, and medical interventions. For patients with uncontrolled elevation of ICP, there are three possible surgical interventions: external ventricular drain placement, evacuation of mass lesion, and/or decompressive craniectomy (unilateral or bilateral). Finally, when patients who underwent craniectomy recover from the acute phase of TBI, cranioplasty is performed for cosmetic purposes and potential neurological benefit.

scholarly journals Continuous ventricular cerebrospinal fluid drainage with intracranial pressure monitoring for management of posttraumatic diffuse brain swelling

2011 ◽  
Vol 69 (1) ◽  
pp. 79-84 ◽  
Author(s):  
Almir Ferreira de Andrade ◽  
Wellingson Silva Paiva ◽  
Robson Luis Oliveira de Amorim ◽  
Eberval Gadelha Figueiredo ◽  
Antonio Nogueira de Almeida ◽  
...  
Keyword(s):  
Intracranial Pressure ◽  
Icp Monitoring ◽  
Brain Swelling ◽  
Monitoring Method ◽  
Simple Method ◽  
Vehicle Accidents ◽  
Brain Injured ◽  
Diffuse Brain Swelling ◽  
Injured Patients ◽  
Diffuse Brain

BACKGROUND: Ventricular drainage has played an important role in the management of traumatic brain-injured patients. The aim of the present study was describe outcomes in a series of 57 patients with diffuse brain swelling underwent to intracranial pressure (ICP) monitoring. METHOD: Fifty-eight patients with diffuse posttraumatic brain swelling, were evaluated prospectively. The Glasgow Coma Scale (GCS) scores of patients varied from 4 to 12. Patients groups divided according to GCS and age. Patient neurological assessment was classified as favorable, unfavorable, and death. RESULTS: Mechanisms of injury were vehicle accidents in 72.4% and falls in 15.6%. 54% of patients had GCS scores between 6 and 8. There were no statistical differences, regarding outcome, between groups separated by age. In the adults group (n=47), 44.7% evolved favorably. CONCLUSION: Our results indicate a poor prognosis in patients with brain swelling. We believe that continuous ventricular CSF drainage with ICP monitoring is a simple method as an adjunct in the management of these patients.

scholarly journals A Novel Noninvasive Technique for Intracranial Pressure Waveform Monitoring in Critical Care

2021 ◽  
Vol 11 (12) ◽  
pp. 1302
Author(s):  
Sérgio Brasil ◽  
Davi Jorge Fontoura Solla ◽  
Ricardo de Carvalho Nogueira ◽  
Manoel Jacobsen Teixeira ◽  
Luiz Marcelo Sá Malbouisson ◽  
...  
Keyword(s):  
Critical Care ◽  
Intracranial Pressure ◽  
Pressure Waveform ◽  
Icp Monitoring ◽  
Amplitude Ratios ◽  
Time Intervals ◽  
Noninvasive Technique ◽  
Time To Peak ◽  
Intracranial Pressure Waveform ◽  
Operator Curve

Background: We validated a new noninvasive tool (B4C) to assess intracranial pressure waveform (ICPW) morphology in a set of neurocritical patients, correlating the data with ICPW obtained from invasive catheter monitoring. Materials and Methods: Patients undergoing invasive intracranial pressure (ICP) monitoring were consecutively evaluated using the B4C sensor. Ultrasound-guided manual internal jugular vein (IJV) compression was performed to elevate ICP from the baseline. ICP values, amplitudes, and time intervals (P2/P1 ratio and time-to-peak [TTP]) between the ICP and B4C waveform peaks were analyzed. Results: Among 41 patients, the main causes for ICP monitoring included traumatic brain injury, subarachnoid hemorrhage, and stroke. Bland–Altman’s plot indicated agreement between the ICPW parameters obtained using both techniques. The strongest Pearson’s correlation for P2/P1 and TTP was observed among patients with no cranial damage (r = 0.72 and 0.85, respectively) to the detriment of those who have undergone craniotomies or craniectomies. P2/P1 values of 1 were equivalent between the two techniques (area under the receiver operator curve [AUROC], 0.9) whereas B4C cut-off 1.2 was predictive of intracranial hypertension (AUROC 0.9, p < 000.1 for ICP > 20 mmHg). Conclusion: B4C provided biometric amplitude ratios correlated with ICPW variation morphology and is useful for noninvasive critical care monitoring.

scholarly journals Non-invasive estimation of intracranial pressure by diffuse optics − a proof-of-concept study

2020 ◽  
Author(s):  
Jonas B Fischer ◽  
Ameer Ghouse ◽  
Susanna Tagliabue ◽  
Federica Maruccia ◽  
Anna Rey-Perez ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Correlation Coefficient ◽  
Correlation Spectroscopy ◽  
Critical Conditions ◽  
Proof Of Concept ◽  
Icp Monitoring ◽  
Concept Study ◽  
Non Invasive

Intracranial pressure (ICP) is an important parameter to monitor in several neuropathologies. However, because current clinically accepted methods are invasive, its monitoring is limited to patients in critical conditions. On the other side, there are other less critical conditions where ICP monitoring could still be useful, thus there is a need to develop non-invasive methods. We propose a new method to estimate ICP based on the analysis of the non-invasive measurement of pulsatile, microvascular cerebral blood flow with diffuse correlation spectroscopy. This is achieved by training a recurrent neural network using only the cerebral blood flow as the input. The method is validated using a 50% split sample method using the data from a proof-of-concept study. The study involved a population of infants (n=6) with external hydrocephalus (initially diagnosed as benign enlargement of subarachnoid spaces) as well as a population of adults (n=6) suffering from traumatic brain injury. The algorithm was applied to each cohort individually to obtain a model and an ICP estimate. In both diverse cohorts, the non-invasive estimation of ICP was achieved with an accuracy less than <4 mmHg and a negligible small bias. Furthermore, we have achieved a good correlation (Pearson's correlation coefficient >0.9) and good concordance (Lin's concordance correlation coefficient >0.9) in comparison to standard clinical, invasive ICP monitoring. This preliminary work paves the way for further investigations of this tool for the non-invasive, bed-side assessment of ICP.

scholarly journals A Novel Noninvasive Technique for Intracranial Pressure Waveform Monitoring in Critical Care

2021 ◽  
Author(s):  
Sérgio Brasil ◽  
Davi Solla ◽  
Ricardo de Carvalho Nogueira ◽  
Manoel Jacobsen Teixeira ◽  
Luiz Marcelo Sá Malbouisson ◽  
...  
Keyword(s):  
Critical Care ◽  
Intracranial Pressure ◽  
Pressure Waveform ◽  
Icp Monitoring ◽  
Amplitude Ratios ◽  
Time Intervals ◽  
Noninvasive Technique ◽  
Time To Peak ◽  
Intracranial Pressure Waveform ◽  
Operator Curve

We validated a new noninvasive tool (B4C) to assess intracranial pressure waveform (ICPW) morphology in a set of neurocritical patients, correlating the data with ICPW obtained from invasive catheter monitoring. Materials and Methods: Patients undergoing invasive intracranial pressure (ICP) monitoring were consecutively evaluated using the B4C sensor. Ultrasound-guided manual internal jugular vein (IJV) compression was performed to elevate ICP from the baseline. ICP values, amplitudes, and time intervals (P2/P1 ratio and time-to-peak [TTP]) between the ICP and B4C waveform peaks were analyzed. Results: Among 41 patients, the main causes for ICP monitoring included traumatic brain injury, subarachnoid hemorrhage, and stroke. Bland-Altman&rsquo;s plot indicated agreement between the ICPW parameters obtained using both techniques. The strongest Pearson&rsquo;s correlation for P2/P1 and TTP was observed among patients with no cranial damage (r = 0.72 and 0.85, respectively) in detriment of those who have undergone craniotomies or craniectomies. P2/P1 values of 1 were equivalent between the two techniques (area under the receiver operator curve [AUROC], 0.9) whereas B4C cut-off 1.2 was predictive of intracranial hypertension (AUROC 0.9, p &lt; 000.1 for ICP &gt; 20 mmHg). Conclusion: B4C provided biometric amplitude ratios correlated with ICPW variation morphology and is useful for noninvasive critical care monitoring.

Development and validation of a questionnaire measuring knowledge, attitudes, and practices (KAP) to healthy eating and activity patterns in school children (HEAPS)

2021 ◽  
pp. 026010602098235 ◽  
Author(s):  
Panchali Moitra ◽  
Preeti Verma ◽  
Jagmeet Madan
Keyword(s):  
Correlation Coefficient ◽  
Healthy Eating ◽  
School Children ◽  
Content Validity ◽  
Activity Patterns ◽  
Intraclass Correlation ◽  
Validity And Reliability ◽  
Attitudes And Practices ◽  
Item Content ◽  
Knowledge Attitudes And Practices

Background: Development of culturally appropriate and psychometrically sound instruments that measure knowledge and health behaviors of children will help to inform appropriate interventions. Aim: To develop and test the validity and reliability of a questionnaire measuring knowledge, attitudes, and practices to healthy eating and activity patterns in school children in India. Methods: Review of literature, focus-group discussions, and theoretical constructs of the Health Belief Model guided the development of an item pool. Face and content validity were assessed by children and a panel of experts and the item content validity, item difficulty, and discrimination indices were calculated. Construct validity was determined using the principal axis method of exploratory factor analysis among a cross-sectional sample of children ( n=252). Internal consistency (Cronbach α values >0.7) and test-retest reliability (intraclass correlation coefficient values >0.75) were estimated. Results: Item content validity index for clarity and relevance were satisfactory (>0.80) and internal consistency for knowledge (Kuder-Richardson 20 = 0.832), attitude (Cronbach’s α = 0.912), and practice items (Cronbach’s α = 0.769) were good. Four factors (children’s eating habits, family dietary practices, and consumption of healthy and unhealthy foods) and two factors (moderate to vigorous activities and sedentary activities) explained 67.7% and 48.2% of the total variance in practice items. Intraclass correlation coefficient estimates ranged from good to excellent (0.72–0.99). Conclusions: The results of the validity and reliability of the 84-item knowledge, attitudes, and practices to healthy eating and activity patterns in schoolchildren questionnaire were promising. The detailed description of the methodology employed may prove useful to researchers conducting similar studies in children.

scholarly journals Correlating Capsaicinoid Levels and Physicochemical Proper-ties of Kimchi and Its Perceived Spiciness

Foods ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 86
Author(s):  
So-Ra Yoon ◽  
Yun-Mi Dang ◽  
Su-Yeon Kim ◽  
Su-Yeon You ◽  
Mina K. Kim ◽  
...  
Keyword(s):  
Correlation Analysis ◽  
Physicochemical Properties ◽  
Correlation Coefficient ◽  
Partial Correlation ◽  
Sugar Content ◽  
Amino Acid Content ◽  
Titratable Acidity ◽  
Free Sugar ◽  
Partial Correlation Analysis ◽  
The Relationship

Capsaicinoid content, among other factors, affects the perception of spiciness of commercial kimchi. Here, we investigated whether the physicochemical properties of kimchi affect the spicy taste of capsaicinoids perceived by the tasting. High-performance liquid chromatography (HPLC) was used to evaluate the capsaicinoid content (mg/kg) of thirteen types of commercial kimchi. The physicochemical properties such as pH, titratable acidity, salinity, free sugar content, and free amino acid content were evaluated, and the spicy strength grade was determined by selected panel to analyze the correlation between these properties. Panels were trained for 48 h prior to actual evaluation by panel leaders trained for over 1000 h according to the SpectrumTM method. Partial correlation analysis was performed to examine other candidate parameters that interfere with the sensory evaluation of spiciness and capsaicinoid content. To express the specific variance after eliminating the effects of other variables, partial correlations were used to estimate the relationships between two variables. We observed a strong correlation between spiciness intensity ratings and capsaicinoid content, with a Pearson’s correlation coefficient of 0.78 at p ≤ 0.001. However, other specific variables may have influenced the relationship between spiciness intensity and total capsaicinoid content. Partial correlation analysis indicated that the free sugar content most strongly affected the relationship between spiciness intensity and capsaicinoid content, showing the largest first-order partial correlation coefficient (rxy/z: 0.091, p ≤ 0.01).

scholarly journals A study of the validity and reliability of the Brazilian version of the Body Shape Questionnaire (BSQ) among adolescents

2009 ◽  
Vol 9 (3) ◽  
pp. 331-338 ◽  
Author(s):  
Maria Aparecida Conti ◽  
Táki Athanássios Cordás ◽  
Maria do Rosário Dias de Oliveira Latorre
Keyword(s):  
Body Image ◽  
Nutritional Status ◽  
Correlation Coefficient ◽  
Internal Consistency ◽  
Body Shape ◽  
Discriminant Validity ◽  
Total Population ◽  
Intraclass Correlation ◽  
The Body ◽  
Validity And Reliability

OBJECTIVES: to produce evidence of the validity and reliability of the Body Shape Questionnaire (BSQ) - a tool for measuring an individual's attitude towards his or her body image. METHODS: the study covered 386 young people of both sexes aged between 10 and 18 from a private school and used self-applied questionnaires and anthropometric evaluation. It evaluated the internal consistency, the discriminant validity for differences from the means, according to nutritional status (underweight, eutrophic, overweight and obese), the concurrent validity by way of Spearman's correlation coefficient between the scale and the Body Mass Index (BMI), the waist-hip circumference ratio (WHR) and the waist circumference (WC). Reliability was tested using Wilcoxon's Test, the intraclass correlation coefficient and the Bland-Altman figures. RESULTS: the BSQ displayed good internal consistency (±=0.96) and was capable of discriminating among the total population, boys and girls, according to nutritional status (p<0.001). It correlated with the BMI (r=0.41; p<0.001), WHR (r=-0.10; p=0.043) and WC (r=0.24; p<0.001) and its reliability was confirmed by intraclass correlation (r=0.91; p<0.001) for the total population. The questionnaire was easy to understand and could be completed quickly. CONCLUSIONS: the BSQ presented good results, thereby providing evidence of its validity and reliability. It is therefore recommended for evaluation of body image attitudes among adolescents.

Urdu Translation and Validation of Activities-Specific Balance Confidence (ABC) Scale

2021 ◽  
Vol 15 (12) ◽  
pp. 3505-3508
Author(s):  
Noor Ul Ain Fatima ◽  
Qurat-Ul- Ain ◽  
Fareeha Kausar ◽  
Mian Ali Raza ◽  
Misbah Waris ◽  
...  
Keyword(s):  
Older Adults ◽  
Construct Validity ◽  
Correlation Coefficient ◽  
Content Validity ◽  
Assessment Tool ◽  
Test Reliability ◽  
Validity And Reliability ◽  
A Value ◽  
Abc Scale ◽  
Translation And Validation

Objective: To translate and validate the ABC-Scale in Urdu language to predict risk of fall in older population. Study design: Cross-cultural Translation and validation Place and Duration: Study was conducted in older adult community of Sialkot from March 2020 to December 2020. Methodology: Translation of ABC in Urdu was conducted by using Beaton et al guidelines. Two bilingual translators translated the original version into Urdu language step wise, correction process was followed. Then two backward translations were done by language expert. After all this process, the translated version was reviewed by the professionals and the final version was applied on 15 individuals. Its reliability and validity was tested on 60 older adults. Results: For test re test reliability, intra class correlation coefficient ICC was measured with a value of 0.984 Which shows good test re-test reliability. The internal consistency and reliability of ABC was calculated by Cronbach’s alpha for total score with a value of 0.985. Content validity was good with values of CVI ranging from 0.767 to 0.955. To test the discriminative validity, independent t test was used to show the difference between the healthy and unhealthy adults. Factor analysis of UABC showed total variance 81.277 and cumulative variance was also 81.277. To calculate construct validity of U-ABC Pearson’s correlation coefficient was used and measured as 0.558. Conclusion: It was concluded that Urdu version of UABC is a valid assessment tool for older adults with fear of fall. It has good content validity, construct validity and reliability. Keywords: activities specific balance scale, validation, Urdu translation, reliability, tool translation

CLINICAL, ECHOGRAPHIC, MORPHOLOGICAL AND IMMUNOLOGICAL CRITERIA FOR EVALUATING A WELL-FOUNDED SCAR ON THE UTERUS AFTER CESAREAN SECTION

2021 ◽  
Vol Special issue (1) ◽  
pp. 57-61
Author(s):  
Venera Kurbaniyazova ◽  
Keyword(s):  
Correlation Analysis ◽  
Cesarean Section ◽  
Correlation Coefficient ◽  
Significant Relationship ◽  
Strong Correlation ◽  
Type I Collagen ◽  
Morphological Features ◽  
Average Degree ◽  
Type I ◽  
Uterine Scar

The results of the conducted studies 102 of the manufacturer testify to the presence of essential clinical and echographic, immunological and morphological features of the "wealthy" or "insolvent" scar on the uterus after the cesarean section. The correlation analysis with the calculation of the Correlation coefficient of Gamma (G) indicates a statistically significant relationship between the average degree between the way of the delivery and the scar thickness (G = 0.55, p = 0.001), strong correlation between the ultrasound data (G = 0.74 , p = 0.002) and antibodies to type I collagen (G = 0.93, p = 0.003). Determining the level of antibodies to the type I collagen is the mostimportant criterion confirming the usefulness of the scar on the uterus.Keywords: cesarean section, uterine scar, pregnancy

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