Non-Nepenthes Carnivorous Plants in Indonesia: Current Knowledge on Diversity, Ethnobotany, and Phytochemistry

One of the most unique plant groups in the world is carnivorous plants. Indonesia is home to many species of this plant group. Nepenthaceae, represented by single genus Nepenthes, is relatively well known, but the others are not. A literature study and several field trips were conducted to give a summary of the diversity and the potential uses of the non-Nepenthes carnivorous plants in Indonesia. Three families with a total number of 29 species have been reported for Indonesia, namely Lentibulariaceae (20 species), Droseraceae (8 species), and Byblidaceae (1 species). One species, Aldrovanda vesiculosa is listed as Endangered based on IUCN Red List. The results reveal that several species possess ethnobotanical and medicinal uses as well as other potential such as in phytoremediation and nanoparticle biosynthesis. Several bioactivities have been reported such as anticancer, antihypertensive, antitumor, antioxidant, antibacterial, or even hepatoprotective. Among the most important bioactivity is anticancer which is supported by the presence of secondary metabolites named plumbagin, which so far has been found in three species. Our result indicates that this plant group is highly potential and warrants further studies and or development.

Fungal–Metal Interactions: A Review of Toxicity and Homeostasis

Metal nanoparticles used as antifungals have increased the occurrence of fungal–metal interactions. However, there is a lack of knowledge about how these interactions cause genomic and physiological changes, which can produce fungal superbugs. Despite interest in these interactions, there is limited understanding of resistance mechanisms in most fungi studied until now. We highlight the current knowledge of fungal homeostasis of zinc, copper, iron, manganese, and silver to comprehensively examine associated mechanisms of resistance. Such mechanisms have been widely studied in Saccharomyces cerevisiae, but limited reports exist in filamentous fungi, though they are frequently the subject of nanoparticle biosynthesis and targets of antifungal metals. In most cases, microarray analyses uncovered resistance mechanisms as a response to metal exposure. In yeast, metal resistance is mainly due to the down-regulation of metal ion importers, utilization of metallothionein and metallothionein-like structures, and ion sequestration to the vacuole. In contrast, metal resistance in filamentous fungi heavily relies upon cellular ion export. However, there are instances of resistance that utilized vacuole sequestration, ion metallothionein, and chelator binding, deleting a metal ion importer, and ion storage in hyphal cell walls. In general, resistance to zinc, copper, iron, and manganese is extensively reported in yeast and partially known in filamentous fungi; and silver resistance lacks comprehensive understanding in both.

Bacterial Synthesis of Nanoparticles: Current Trends in Biotechnology and Biomedical Fields

On estimation scales ranging from 0.1 nm to 100 nm, the nanoscale is part of the capacitance components of the physical-synthetic and natural environment. Dimensionality, morphology, structure, uniformity, and agglomeration are all used to classify nanoparticles. Its functionality and effect on the environment and species are influenced by its shape and morphology. The priority research is to determine the effects of nanoparticles on any biological entity that is necessary when designing nanotechnology-based biotechnological and biomedical products. Bacteria have a remarkable ability to reduce metal ions, making them one of the most promising candidates for nanoparticle biosynthesis. Nanoparticles have been researched in the biomedical field for antimicrobial, biosensor, diagnostic imaging, and drug delivery applications. These natural technologies appear to be capable of producing stable nanoparticles with well-defined dimensions, morphologies, and compositions by optimizing reaction conditions and selecting the best bacteria. This work includes a list of the most commonly used microorganisms and associated Nanoparticles, as well as a discussion of current biotechnology and biomedical developments.

Optimisation of Zinc Oxide Nanoparticle Biosynthesis Using Saccharomyces Cerevisiae with Box-Behnken Design

Zinc oxide nanoparticles have wide applications as catalysts, antimicrobial agents, drug delivery agents, etc. because of their intrinsic properties. Various methods can be applied to synthesise nanoparticles, one of which is the biosynthesis process. Biosynthesis is more eco-friendly than chemical and physical methods. In the present study, the optimisation of zinc oxide nanoparticle biosynthesis using the yeast Saccharomyces cerevisiae was performed by applying a response surface method called the Box�Behnken design (BBD). Three factors were optimised in the present study, namely the concentration of zinc acetate as the precursor (X1), concentration of the S. cerevisiae fermentation broth (X2), and the incubation time (X3). The mass of zinc oxide nanoparticles (Y) was recorded as the response of the experiment. The product was then characterised by fourier transform infrared spectroscopy (FTIR), X-Ray diffraction (XRD), scanning electron microscopy/energy dispersive spectroscopy (SEM/EDS), and particle size analyser (PSA). The optimum conditions for the preparation of zinc oxide nanoparticles were found to be 0.3 M, 100% (v/v), and 24 h as the zinc acetate concentration, medium concentration, and incubation time, respectively. The FTIR analysis showed peaks at ~600 cm−1, which is characteristic for ZnO stretching. From the XRD result, the ZnO nanoparticles with hexagonal structure was confirm. The SEM/EDS analysis confirmed that the morphology was spherical and showed the major energy emission for zinc and oxygen. Moreover, the PSA analysis revealed that the smallest size was 218.6 nm (12%) when the synthesis was performed at the optimum conditions, while when the incubation time was prolonged for 120 h, the size decreased to 134.2 nm.

Palladium nanoparticle biosynthesis via Yerba Mate (Ilex paraguariensis) extract: an efficient eco-friendly catalyst for Suzuki–Miyaura reactions

This manuscript relates, for the first time, palladium nanoparticle production by bio-reduction using an Ilex paraguariensis aqueous extract. The solid obtained, PdISM, was used as a catalyst in Suzuki–Miyaura cross-coupling, composing a new eco-friendly, ligand-free, and low cost catalytic system. Excellent yields were obtained in the coupling of aryl iodides and bromides with phenylboronic acid. The same catalyst load was able to be recycled 3x. Graphical Abstract

Bacterial Synthesis of Nanoparticles: Current Trends in Biotechnology and Biomedical Fields

On estimation scales ranging from 0.1 nm to 100 nm, the nanoscale is part of the capacitance components of the physicalsynthetic and natural environment. Dimensionality, morphology, structure, uniformity, and agglomeration are all used to classify nanoparticles. Its functionality and effect on the environment and species are influenced by its shape and morphology. The priority research is to determine the effects of nanoparticles on any biological entity that is necessary when designing nanotechnology-based biotechnological and biomedical products. Bacteria have a remarkable ability to reduce metal ions, making them one of the most promising candidates for nanoparticle biosynthesis. Nanoparticles have been researched in the biomedical field for antimicrobial, biosensor, diagnostic imaging, and drug delivery applications. These natural technologies appear to be capable of producing stable nanoparticles with well-defined dimensions, morphologies, and compositions by optimizing reaction conditions and selecting the best bacteria. This work includes a list of the most commonly used microorganisms and associated Nanoparticles, as well as a discussion of current biotechnology and biomedical developments.

Bioengineered metal and metal oxide nanoparticles for photocatalytic and biological applications: A review

In this modern era, (M/MO-NPs) Metal/metal oxide nanoparticles are utilized in various areas. The growth of nanoparticles is tremendous in our daily activities like beauty products, doses, delivery of drugs, and outfit. They can be set up by numerous strategies, for example, green amalgamation and the ordinary compound blend techniques. Green synthesis incorporates endless increase to deliver M/MO-NPs with requesting properties. In Bioengineering, the "green" combination has increased massive consideration as a trustworthy, dependable, and natural benevolent convention for orchestrating a wide scope of Nanomaterials including M/MO-NPs and bio propelled materials. Be that as it may, the utilization of plant extracts for this intention is profitable over organisms because of usability and less biohazard. Union of metal and MO-NPs by using the extract of plant fluid arrangement have increased consideration toward the green methodology and with no antagonistic impact on nature. The current article intends to survey the advancement made lately on nanoparticle biosynthesis by organisms. These microbial assets incorporate microorganisms, organisms, yeast, green growth, and viruses. This study predominantly centers on the biosynthesis of the most usually examined M/MO-NPs, for example, copper, cadmium, noble metals, platinum, titanium oxide, palladium, zinc oxide, and cadmium sulfide.

Microorganisms as nano-factories for metal nanoparticles synthesis

: Nanoparticles applications have revolutionized the different areas of the research. These include medicine, surgery, drug delivery, wastewater treatment, agriculture, cancer therapy, etc. The use of nanoparticles is increasing day by day to their popular, promising characteristics. With the excessive use of the nanoparticles, their accumulation in the organisms and different environments have been reported. A very high increase in the accumulation and toxicity of the nanoparticles nanoparticle been reported in this decade. Therefore, the nanoparticle research has been now shifted to find new techniques and methods to minimize the toxic effects of the nanoparticles. In this context, the requirement of a safe design approach and the generation of fewer toxic nanoparticles is required. One of the eco-friendly approaches for safer nanoparticles synthesis is the use of living organisms for nanoparticles production. Microbes especially, bacteria, fungi and yeasts, are considered safe, secure, and efficient systems for nanoparticle biosynthesis. This review is an attempt to understand the potential of the microbes for biosynthesis of nanoparticles.