Influence of Source Parameters on the Polarization Properties of Beams for Practical Free-Space Quantum Key Distribution

Polarization encoding has been extensively used in quantum key distribution (QKD) implementations along free-space links. However, the calculation model to characterize channel transmittance and quantum bit error rate (QBER) for free-space QKD has not been systematically studied. As a result, it is often assumed that misalignment error is equal to a fixed value, which is not theoretically rigorous. In this paper, we investigate the depolarization and rotation of the signal beams resulting from spatially-dependent polarization effects of the use of curved optics in an off-axis configuration, where decoherence can be characterized by the Huygens–Fresnel principle and the cross-spectral density matrix (CSDM). The transmittance and misalignment error in a practical free-space QKD can thus be estimated using the method. Furthermore, the numerical simulations clearly show that the polarization effect caused by turbulence can be effectively mitigated when maintaining good beam coherence properties.

Expression Based Species Deconvolution and Realignment Removes Misalignent Error in Multi-species Single Cell Data

Background: Although single cell RNAseq of xenograft samples are widely used, there is no comprehensive pipeline for human and mouse mixed single cell analysis. Method: We used public data to assess misalignment error when using human and mouse combined reference, and generated a pipeline based on expression-based species deconvolution with species matching reference realignment to remove errors. We also found false-positive signals presumed to originate from ambient RNA of the other species, and use computational method to adequately remove them. Result: Misaligned reads account to on average 0.5% of total reads but expression of few genees were greatly affected leading to 99.8% loss in expression. Human and mouse mixed single cell data analyzed by our pipeline clustered well with unmixed data. We also applied our pipeline to multi-species multi-sample single cell library containing breast cancer xenograft tissue and successfully identified all identities along with the diverse cell types of tumor microenvironment. Conclusion: We present our pipeline for mixed human and mose single cell data which can also be applied to pooled libraries to obtain cost effective single cell data. We also address consideration points when analyzing mixed single cell data for future development.

Misalignment Error in Cancellous Bone Apparent Elastic Modulus Depends on Bone Volume Fraction and Degree of Anisotropy

Cancellous bone is an anisotropic structure with architectural and mechanical properties that vary due to both skeletal site and disease state. This anisotropy means that, in order to accurately and consistently measure the mechanical properties of cancellous bone, experiments should be performed along the primary mechanical axis (PMA), that is, the orientation in which the mechanical properties are at their maximum value. Unfortunately, some degree of misalignment will always be present, and the magnitude of the resulting error is expected to be architecture dependent. The goal of this work is to quantify the dependence of the misalignment error, expressed in terms of change in apparent elastic modulus (ΔE), on both the bone volume fraction (BV/TV) and the degree of anisotropy (DA). Finite element method (FEM) models of bovine cancellous bone from five different skeletal sites were created at 5 deg and 20 deg from the PMA determined for each region. An additional set of models was created using image dilation/erosion steps in order to control for BV/TV and better isolate the effect of DA. Misalignment error was found to increase with increasing DA and decreasing BV/TV. At 5 deg misaligned from the PMA, error is relatively low (<5%) in all cases but increases to 8–24% error at 20 deg. These results suggest that great care is needed to avoid introducing misalignment error into experimental studies, particularly when studying regions with high anisotropy and/or low bone volume fraction, such as vertebral or osteoporotic bone.

An Improved Calibration Method for the Misalignment Error of a Triaxial Magnetometer and Inertial Navigation System in a Three-Component Magnetic Survey System

In order to calibrate the misalignment error of a triaxial magnetometer and an inertial navigation system in a three-component magnetic survey system, an improved method with easy realization is proposed in this paper. We establish the misalignment error model based on Euler’s theorem. We transform the calibration of misalignment error into estimating calibration parameters to minimize the value of objective function. Then, the nonlinear least squares method is used to estimate the calibration parameters. In the simulation experiment, the deviation between the value and the preset value is within 1 nT. In the field experiment, the fluctuation value of the x, y, and z components reduce to 1.09%, 0.92%, and 1.28%, respectively. The absolute deviation values are reduced to 0.72%, 0.70%, and 0.81% and the standard deviation value are reduced to 0.74%, 0.71%, 0.86%, respectively. The proposed method has advantages of high operability and precision as compared with existing methods.

The Feasibility of Remotely Piloted Aircrafts for VOR Flight Inspection

This article analyzes the use of Remotely Piloted Aircrafts (RPA) in VOR (Very High Frequency Omnidirectional Range) flight inspection. Initially, tests were performed to check whether the Autopilot Positioning System (APS) met the regulatory requirements. The results of these tests indicated that the APS provided information within the standard regulations. A Hardware in the Loop (HIL) platform was implemented to perform flight tests following the waypoints generated by a mission automation routine. One test was performed without introducing disturbance into the proposed test platform. The other four tests were performed introducing errors in latitude and longitude in the APS into the platform. The errors introduced had the same characteristics as those measured in the initial tests, in order for the simulation tests to be as similar as possible to the real situation. The tests performed with positioning errors only did not lead to false misalignment detection. However, introducing positioning errors and a 4° VOR misalignment error, a misalignment of 3.99° was observed during the flight test. This is a value greater than the maximum one allowed by the regulations, and the system indicates the VOR misalignment. Five flight inspection tests were performed. In addition to the APS errors, tests with a modulation error were also conducted. Introducing a 4° VOR misalignment in conjunction with modulation error, a misalignment of 4.02° was observed, resulting in successful misalignment detection.