Executive Dysfunctions in Schizophrenia: A Critical Review of Traditional, Ecological and Virtual Reality Assessments

In recent years, interest has grown in measuring executive function in schizophrenia with ecological and virtual reality (VR) tools. However, there is a lack of critical analysis comparing those tools with traditional ones. This paper aims to characterize executive dysfunction in schizophrenia by comparing ecological and virtual reality assessments with traditional tools, and to describe the neurobiological and psychopathological correlates. The analysis revealed that ecological and VR tests have higher levels of verisimilitude and similar levels of veridicality compared to traditional tools. Both negative symptoms and disorganization correlate significantly with executive dysfunction as measured by traditional tools, but their relationships with measures based on ecological and VR methods are still unclear. Although there is much research on brain correlates of executive impairments in schizophrenia with traditional tools, it is uncertain if these results will be confirmed with the use of ecological and VR tools. In the diagnosis of executive dysfunction, it is important to use a variety of neuropsychological methods—especially those with confirmed ecological validity—to properly recognize the underlying characteristics of the observed deficits and to implement effective forms of therapy.

Measuring dlPFC Signals to Predict the Success of Merchandising Elements at the Point-of-Sale – A fNIRS Approach

The (re-)launch of products is frequently accompanied by point-of-sale (PoS) marketing campaigns in order to foster sales. Predicting the success of these merchandising elements at the PoS on sales is of interest to research and practice, as the misinvestments that are based on the fragmented PoS literature are tremendous. Likewise, the predictive power of neuropsychological methods has been demonstrated in various research work. Nevertheless, the practical application of these neuropsychological methods is still limited. In order to foster the application of neuropsychological methods in research and practice, the current research work aims to explore, whether mobile functional near-infrared spectroscopy (fNIRS) – as a portable neuroimaging method – has the potential to predict the success of PoS merchandising elements by rendering significant neural signatures of brain regions of the dorsolateral prefrontal cortex (dlPFC), highlighting its potential to forecast shoppers’ behaviour aka sales at the PoS. Building on previous research findings, the results of the given research work indicate that the neural signal of brain regions of the dlPFC, measured with mobile fNIRS, is able to predict actual sales associated with PoS merchandising elements, relying on the cortical relief effect. More precisely, the research findings support the hypothesis that the reduced neural activity of brain regions associated with the dlPFC can predict sales at the PoS, emphasising another crucial neural signature to predict shoppers’ purchase behaviour, next to the frequently cited reward association system. The research findings offer an innovative perspective on how to design and evaluate PoS merchandising elements, indicating fruitful theoretical and practical implications.

TRANSDISCIPLINARY APPROACH TO SPEECH THERAPY WITH CHILDREN WITH ALALIA

The article discloses the practical side of the transdisciplinary approach in speech therapy work and rehabilitation of children with alalia. In diagnosing speech disorders, the author believes that the behavior of children with alalia is closely related to the physiological activity of the brain, that diagnosis of speech disorders based on EEG and neuropsychological methods, as well as knowledge of the insufficiency of individual brain structures, which is supported by data from electroencephalographic research, are important for speech therapists in complex rehabilitation. Binaural therapy (individual alpha balance correction program) was used for children after EEG diagnosis of their dominant alpha rhythm, which matched their dominant rhythm in the selected time interval.

Social cognition, behaviour and therapy adherence in frontal lobe epilepsy: a study combining neuroeconomic and neuropsychological methods

Social behaviour of healthy humans and its neural correlates have been extensively studied in social neuroscience and neuroeconomics. Whereas it is well established that several types of epilepsies, such as frontal lobe epilepsy, lead to social cognitive impairments, experimental evidence on how these translate into behavioural symptoms is scarce. Furthermore, it is unclear whether social cognitive or behavioural disturbances have an impact on therapy adherence, which is critical for effective disease management, but generally low in these patients. In order to investigate the relationship between social cognition, social behaviour, and therapy adherence in patients with frontal lobe epilepsies (FLE), we designed a study combining conventional neuropsychological with behavioural economic and functional magnetic resonance imaging (fMRI) methodology. Fifteen patients and 15 healthy controls played a prisoners' dilemma game (an established game to operationalize social behaviour) while undergoing fMRI. Additionally, social cognitive, basic neuropsychological variables, and therapy adherence were assessed. Our results implicate that social behaviour is indeed affected and can be quantified using neuroeconomic methods in patients with FLE. Impaired social behaviour in these patients might be a consequence of altered brain activation in the medial prefrontal cortex and play a role in low therapy adherence. Finally, this study serves as an example of how to integrate neuroeconomic methods in neurology.

Lateralization Profile in ASD Children with Different Speech Development Levels

The lateralization profile and its link to speech development in 10 children with autism spectrum disorders and 20 neurotypical controls aged 6-7 were studied. Neuropsychological methods for the dominant arm, dominant ear, and dominant eye determination were used as well as for expressive and impressive speech assessment. Ambilateral results were found more often in autism spectrum disorders children compared to neurotypical controls. autism spectrum disorders children with ambilateral rates prevalence have shown higher results in speech development. There were more left ear dominance cases among autism spectrum disorders children compared with controls.

Features of the Development of the Cognitive Sphere in Children with Different Online Activities: Is There a Golden Mean?

The paper presents the results of a comparative study of cognitive functions in preschoolers (5—7 years old, n=50), elementary school students (7—11 years old, n=50), younger adolescents (12—13 years old, n=53), and older adolescents (14—16 years old, n=47) with different intensity of daily use of digital devices: low, medium, controlled high, and uncontrollably high. A battery of neuropsychological methods was used to study the state of cognitive functions. The main differences in accordance with online activity were found in groups of elementary school students and younger adolescents: results were obtained confirming that children using the Internet at medium frequency (1—3 hours per day) are effective in performing a number of cognitive tasks (regulation, control, dynamical praxis, verbal and visual-spatial functions, and neurodynamics). In this study, a certain optimum of online activity time was outlined for different age groups, in the presence of which higher levels of development of certain cognitive functions are recorded.