The importance of introducing lead generation is that it is the most basic activity before publishing an advertisement or conducting any other strategic activity on the Internet. Advertisements formed by a true understanding of the target customers, their wants, motives, and the main reasons for purchasing are more efficient and effective. Thus, marketers always try to adapt their solution based on the sensitive needs and wants of their audience. These efforts of marketers on the one hand, and emergence of new technologies in interactive media on the other, have led to the creation of a new concept of lead generation in marketing and online advertising with the responsibility of collecting information, trends, and surfing methods of various customers. This chapter focuses on lead generation as a new responsibility of interactive agencies and its role in B2B and B2C. Also, the way of launching a successful lead generation strategy will be reviewed, and new concepts such as behavioral targeting and behavioral marketing will be mentioned. Meanwhile, by studying forums and online communities, the chapter will show how focus groups based on traditional marketing research are being replaced by free online focus groups. The main emphasis of this chapter is the application of new technologies for making Internet advertising more effective.