scholarly journals Smoking, body weight, physical exercise, and risk of lower limb total joint replacement in a population-based cohort of men

2011 ◽  
Vol 63 (8) ◽  
pp. 2523-2530 ◽  
Author(s):  
George Mnatzaganian ◽  
Philip Ryan ◽  
Paul E. Norman ◽  
David C. Davidson ◽  
Janet E. Hiller
Keyword(s):  
Body Weight ◽  
Physical Exercise ◽  
Joint Replacement ◽  
Lower Limb ◽  
Total Joint Replacement ◽  
Population Based

scholarly journals Hereditary and environmental factors causing total joint replacement due to hip and knee osteoarthritis – a twin registry based prospective cohort study

2016 ◽  
Vol 26 (1-2) ◽  
Author(s):  
Karin Magnusson ◽  
Kåre Birger Hagen
Keyword(s):  
Environmental Factors ◽  
Knee Joint ◽  
Joint Replacement ◽  
Total Joint Replacement ◽  
Population Based ◽  
Genetic Contribution ◽  
Questionnaire Response ◽  
Knee Oa ◽  
Relative Contribution ◽  
Twin Registry

The relative contribution of genetic factors and more modifiable environmental factors to a clinically<br />relevant osteoarthritis (OA) diagnosis is unkown. In this paper we present an ongoing study on the genetic<br />contribution to total joint replacement (TJR) due to hip and knee OA and effects of lifestyle and lifestyle<br />related conditions on TJR due to OA. We have linked data on incident OA from the Norwegian Arthroplasty<br />Registry were l with the Norwegian Twin Registry on the National ID number in 2014, thus obtaining a<br />population based cohort of same-sex twins born 1915-60. Data on height, weight and lifestyle were selfreporteded<br />in questionnaires conducted between 1978 and 1992. The monozygotic (MZ) and dizygotic<br />(DZ) concordances as well as the genetic contribution vs. contribution of more modifiable, environmental<br />factors to arthroplasty will be examined in separate analyses for the hip and the knee joint. The sample<br />comprised N=18058 twins (N=3803 MZ and N=5226 DZ pairs) including N=9650 (53.4%) females and a<br />mean (SD) age of 38 (12.3) years at questionnaire response. Some preliminary analyses have been performed<br />showing a higher concordance for TJR due to hip OA among MZ (0.36) than DZ twins (0.16), which may<br />be consistent with a genetic contribution to hip OA. TJR due to hip OA may be determined by genetic<br />factors. Results for the knee joint as well as final results from hereditary analyses and co-twin control<br />analyses of will be published consecutively from 2016.

scholarly journals Comparison of Total Joint Replacement Rate Between Patients With Hemophilia A and Patients With Hemophilia B: A Population-Based and Retrospective Cohort Study

2018 ◽  
Vol 24 (9_suppl) ◽  
pp. 163S-170S
Author(s):  
Wen-Ya Lin ◽  
Jiaan-Der Wang ◽  
Yu-Tse Tsan ◽  
Wei-Cheng Chan ◽  
Kwok-Man Tong ◽  
...  
Keyword(s):  
Joint Replacement ◽  
Hemophilia A ◽  
Total Joint Replacement ◽  
Population Based ◽  
Hemophilia B ◽  
Clotting Factor ◽  
Research Database ◽  
Increased Risk ◽  
The Difference ◽  
Factor Concentrate

Recurrent hemarthrosis in patients with hemophilia (PWH) results in chronic arthropathy requiring total joint replacement (TJR). This study aimed to compare the difference in TJR rate between patients with hemophilia A (HA) and hemophilia B (HB). A final total of 935 PWH (782 HA and 153 HB) without inhibitors were collected from the Taiwan’s National Health Insurance Research Database between 1997 and 2013. Demographics, clinical characteristics, and TJR rate were compared between the 2 groups. The annual use of clotting factor concentrate was not different between HA and HB groups ( P = .116). The rate of comorbidities except for 29 PWH having HIV who were all in the HA group was also not different between the 2 groups. A total of 99 (10.6%) PWH had undergone 142 TJR procedures during the study period. All of them had received on-demand therapy. No difference was found in the cumulative incidence of TJR between HA and HB ( P = .787). After adjusting for various confounders including age, pyogenic arthritis, and HIV infection, no increased risk of TJR was found in patients with HA versus Patients with HB (hazard ratio: 0.92, 95% confidence interval 0.54-1.58). This finding suggests that the rate of TJR between patients with HA and HB is not significantly different.

scholarly journals Effects of Protein Supplementation Combined with Exercise Training on Muscle Mass and Function in Older Adults with Lower-Extremity Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Trials

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2422
Author(s):  
Chun-De Liao ◽  
Yen-Tzu Wu ◽  
Jau-Yih Tsauo ◽  
Pey-Rong Chen ◽  
Yu-Kang Tu ◽  
...  
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Exercise Training ◽  
Muscle Mass ◽  
Joint Replacement ◽  
Lower Limb ◽  
Functional Outcomes ◽  
Total Joint Replacement ◽  
Meta Analysis ◽  
Protein Supplementation

Aging and osteoarthritis (OA) are associated with a high risk of muscle mass loss, which can lead to physical disability. This study investigated the effectiveness of protein supplementation combined with exercise training (PS + ET) in improving muscle mass and functional outcomes in older adults with lower-limb OA. A comprehensive search of online databases was performed to identify randomized controlled trials (RCTs) on the effectiveness of PS + ET in older adults with hip or knee OA. Meta-analysis and risk of bias assessment of the included RCTs were conducted. Six RCTs were included in this systemic review; they had a median (range/total) Physiotherapy Evidence Database (PEDro) score of 7 (6–9) out of 10, respectively. Five RCTs that enrolled patients who underwent total joint replacement were included in this meta-analysis. The PS + ET group exhibited significant improvements in muscle mass (standard mean difference [SMD] = 1.13, p < 0.00001), pain (SMD = 1.36, p < 0.00001), and muscle strength (SMD = 0.44, p = 0.04). Our findings suggest that PS + ET improves muscle mass, muscle strength, and functional outcomes and reduces pain in older adults with lower-limb OA, particularly in those who have undergone total joint replacement.

scholarly journals Demography of Total Joint Replacement Surgeries Performed in a Tertiary Care Hospital: A Cross-sectional Survey

2021 ◽  
Vol 59 (243) ◽  
pp. 1161-1165
Author(s):  
Shrawan Kumar Thapa ◽  
Manoj Kandel ◽  
Sunil Panta ◽  
Bishwa Raj Adhikari
Keyword(s):  
Knee Replacement ◽  
Joint Replacement ◽  
Lower Limb ◽  
Hip Replacement ◽  
Tertiary Care Hospital ◽  
Total Joint Replacement ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cross Sectional Survey ◽  
Cross Sectional

Introduction: Total joint replacement of hip and knee is considered as one of the most successful orthopedic surgeries in the twenty-first century because of the only solution to end-stage arthritis of these joints. The real burden of the problem is yet to be established in developing countries like Nepal. This study aims to describe the demographic findings of the joint replacement surgeries among total lower limb surgeries in a tertiary care hospital. Methods: This cross-sectional survey was conducted using the hospital records of 73 total joint replacement surgeries of the lower limb in the Department of Orthopedics of a tertiary care hospital from November 2016 to November 2020. Ethical approval was taken from the Institutional Review Committee (reference number: 077/78-011). Convenience sampling was done. Data analysis was done using the Statistical Package for the Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data. Results: There were 73 total joint replacement of hips and knees. Of which, 32 (43.84%) total hip replacements were done in which one (3.13%) patient had a simultaneous bilateral hip replacement in single-stage and the other one (3.13%) had two-stage bilateral hip replacement. Forty one (56.16%) total knee replacements were done in which 18 (24.65%) had a simultaneous bilateral knee replacement and five (6.85%) had a unilateral knee replacement. Conclusions: Total joint replacements of the hip were more common among the lower limb surgeries.

AB0958 Assessment of quality of life in patients undergoing total joint replacement for OA of the lower limb

2013 ◽  
Vol 71 (Suppl 3) ◽  
pp. 693.9-693
Author(s):  
A. Neuprez ◽  
G. François ◽  
O. Bruyère ◽  
V. Kovats ◽  
T. Thirion ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Joint Replacement ◽  
Lower Limb ◽  
Total Joint Replacement
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