scholarly journals Comparison between in vitro and in vivo cartilage overloading studies based on a systematic literature review

2018 ◽  
Vol 36 (8) ◽  
pp. 2076-2086 ◽  
Author(s):  
Mieke Nickien ◽  
Ashley Heuijerjans ◽  
Keita Ito ◽  
Corrinus C. van Donkelaar
Keyword(s):  
Literature Review ◽  
Systematic Literature Review

scholarly journals Intraoral Fluoride-Releasing Devices: A Literature Review

2012 ◽  
Vol 3 (4) ◽  
pp. 350-354 ◽  
Author(s):  
Jagjit Singh ◽  
Gurminder Singh ◽  
Ramandeep Singh Gambhir ◽  
Daljit Kapoor ◽  
Heena Kakar
Keyword(s):  
Dental Caries ◽  
Literature Review ◽  
Fluoride Concentration ◽  
Risk Groups ◽  
High Caries Risk ◽  
Release Devices ◽  
Topical Fluorides

ABSTRACT Dental caries still continues to be a problem for majority of the individuals and it can be a serious problem for medically compromised, developmentally disabled and elderly individuals. Water fluoridation, systemic and topical fluorides are used for past many years to supply supplemental fluoride in order to combat dental caries. The latest fluoride research is investigating the use of slow-release devices for the long-term intraoral provision of fluoride. The present review addresses two main types of intraoral fluoride-releasing devices like the copolymer membrane device, glass device containing fluoride and some variations of these devices. These devices can significantly increase the salivary fluoride concentration without substantially affecting the urinary fluoride levels. A significant number of studies have confirmed that intraoral fluoride-releasing devices have great potential for use in preventing dental caries in children, high-caries-risk groups, and irregular dental attenders in addition to a number of other applications. As most of the studies done on these devices are in vitro and in vivo studies, more well-designed clinical trials are necessary to evaluate the results so that these devices can be used clinically. How to cite this article Gambhir RS, Kapoor D, Singh G, Singh J, Kakar H. Intraoral Fluoride-Releasing Devices: A Literature Review. World J Dent 2012;3(4):350-354.

Direct in vivo strain measurements in human bone—A systematic literature review

2012 ◽  
Vol 45 (1) ◽  
pp. 27-40 ◽  
Author(s):  
R. Al Nazer ◽  
J. Lanovaz ◽  
C. Kawalilak ◽  
J.D. Johnston ◽  
S. Kontulainen
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
Human Bone ◽  
Strain Measurements

MAPPING IN VITRO AND IN VIVO DERIVED CYP2C9 AND CYP2C19 ONTOGENY FUNCTIONS: A CRITICAL COMPARISON BETWEEN VARIOUS ONTOGENY MODELS

2015 ◽  
Vol 101 (1) ◽  
pp. e1.38-e1 ◽  
Author(s):  
Farzaneh Salem ◽  
Trevor Johnson ◽  
Amin Rostami-Hodjegan
Keyword(s):  
Literature Review ◽  
Microsomal Protein ◽  
Critical Comparison ◽  
Physiologically Based Pharmacokinetic ◽  
Age Related ◽  
Physiologically Based ◽  
Age Range ◽  
Best Fit

In vivo derived ontogeny profiles for CYP1A2 and CYP3A4, show improved clearance (CL) predictions within a paediatric physiologically based pharmacokinetic (p-PBPK) model1. The aim of this study is to derive ontogeny functions (OF) for CYP2C9 and CYP2C19 based on age related CL data on ibuprofen and pantoprazole & lansoprazole, respectively.A literature review was undertaken to collect age related CL data for these probes, the values were deconvoluted back to intrinsic CL values (per mg of liver microsomal protein) as described previously. The 'best-fit' algorithm for ratio of paediatric to mean adult intrinsic CL with age was determined in Graphpad Prism5 to obtain in vivo OF for CYP2C9 and CYP2C19. These were compared for performance with previously established ‘in vitro' OF in Simcyp Paediatric simulator (v14) using validation datasets.CYP2C9 and CYP2C19 enzyme activities showed an increase with age to values higher than adults by ages 2 and 1 month respectively, maximum values were reached at 1.5 years and 6 months, respectively before declining to typical adult levels by around 25 years.The CYP2C9 in vivo derived OF led to improved predictions of diclofenac and S-Warfarin CL compared to in vitro derived OF across the age range. For CYP2C19 there is a dearth of suitable validation compounds due to lack of clinical data with a possibility of using omeprazole or voriconazole. The reasons for discrepancy between in vitro and in vivo derived OF require further investigation.

scholarly journals Treatment of Dental Caries with Diamine Silver Fluoride: Literature Review

2018 ◽  
Vol 20 (3) ◽  
pp. 152
Author(s):  
Marília Franco Punhagui ◽  
Jaqueline Costa Favaro ◽  
Beatriz Brandão Sacarpelli ◽  
Ricardo Danil Guiraldo ◽  
Murilo Baena Lopes ◽  
...  
Keyword(s):  
Literature Review ◽  
Data Extraction ◽  
Caries Prevention ◽  
In Vivo Studies ◽  
Permanent Teeth ◽  
Cochrane Library ◽  
Silver Diamine Fluoride ◽  
Non Invasive

AbstractBrazilian health care programs recommend the use of cariostatic solutions of silver diamine fluoride (SDF) or sodium fluoride varnishes for children 0 to 3 years old with high or moderate caries activity for the control of caries lesions. SDF is a safe, economical, efficient and non-invasive coadjuvant agent, exerting an antibacterial action capable of reducing superficial mineral loss of the enamel and can be used in the treatment of deciduous and permanent teeth. The objective of this literature review was to gather current information on describing the mechanism of SDF action’ and its clinical application in young children in caries prevention and paralysis. The PubMed / Medline and Cochrane Library databases were accessed by identifying the relevant studies published in English from 1960 to May 2017. The search strategy employed the keywords: “Silver diamine fluoride” and “Children “or “Infant” and “Caries prevention”. Data extraction was performed in: 19 in vitro studies; 10 review articles and 8 in vivo studies. It was possible to conclude that SDF is almost twice as effective compared to fluoride varnish in caries paralysis. However, the contact time of the solution and the optimal frequency of application of the SDF are still undefined, inducing new projects and clinical studies in the search for an adequate clinical protocol of this cariostatic.Keywords: Preventive Dentistry. Children. Dental Caries.Resumo Os programas de assistência à saúde brasileiros recomendam para o controle das lesões de cárie a utilização de soluções cariostáticas de diamino fluoreto de prata - DFP ou vernizes de fluoreto de sódio para crianças de 0 a 3 anos com atividade de cárie alta ou moderada. O DFP é agente coadjuvante seguro, econômico, eficiente e não invasivo, exercendo ação antibacteriana capaz de reduzir a perda mineral superficial do esmalte e, pode ser utilizado no tratamento de dentes decíduos e permanentes. O objetivo desta revisão de literatura foi reunir informações atuais sobre descrever o mecanismo de ação do DFP e sua aplicação clínica em crianças de pouca idade na prevenção e paralisação da cárie. As bases de dados PubMed/Medline e Cochane Library foram acessadas identificando os estudos relevantes publicados em inglês, no período de 1960 a maio de 2017. A estratégia de busca empregou as palavras-chave: “Silver diamine fluoride” and “Children” or “Infant” and “Caries prevention”. A extração dos dados foi realizada em: 19 estudos in vitro; 10 artigos de revisão e 8 estudos in vivo. Foi possível concluir que o DFP apresenta-se quase duas vezes tão eficaz comparado ao verniz fluoretado na paralização de cárie. Porém, o tempo de contato da solução e a frequência ótima de aplicação do DFP ainda estão indefinidos, suscitando novos projetos e estudos clínicos na busca de adequado protocolo clínico deste cariostático.Palavra-chave: Odontologia Preventiva. Criança. Carie Dentária. 

scholarly journals Phytochemical compounds and pharmacological activities of lemon (Citrus limon L.) – Update Review

2021 ◽  
Vol 12 (2) ◽  
pp. 1496-1505
Author(s):  
Hartati R ◽  
Insanu M ◽  
Mudrika S. N. ◽  
Fidrianny I
Keyword(s):  
Literature Review ◽  
Southeast Asia ◽  
Citrus Limon ◽  
Pharmacological Activities ◽  
The World ◽  
Phytochemical Compounds ◽  
Ancient Times

The lemon plant (Citrus limon L.) is a species from the Rutaceae family that spread from Southeast Asia and spread to all countries in the world. Lemon has been used traditionally since ancient times to treat various diseases and has been tested for various pharmacological activities. The literature review was carried out to study the phytochemical compounds and pharmacological activities of lemon plants. The literature compiled by a minimum of 50 scientific articles using search engines such as Science Direct, Pubmed, and Google Scholar, published for a maximum of the last 10 years, includes a minimum of 20 articles in the last 2 years, has a DOI, and the quality of the journal index is reviewed using Scimago. Lemon is very rich in phytochemical compounds, including flavanones such as hesperidin, eriocytrin, naringin, narirutin, didymin; flavones such as apigenin, luteolin, and diosmin; flavonols such as routine, quercetin, mirisetin, isositrol, limositrol, and limositrin; terpenoids such as limonene, limonoids, and carotenoids. Various kinds of in vivo and in vitro studies provide results of various pharmacological activities such as antioxidants, anticancer, neuroprotective, antimicrobial, antidiabetic, anti-inflammatory, antihyperlipidemic, antiurolithiasis, and antiplasmodial. It is necessary to develop further research on the pharmacological activity of lemon plants in the future.

scholarly journals Pharmacological and Therapeutic Potential of Myristicin: A Literature Review

Molecules ◽  
2021 ◽  
Vol 26 (19) ◽  
pp. 5914
Author(s):  
Elisa Frederico Seneme ◽  
Daiane Carla dos Santos ◽  
Evelyn Marcela Rodrigues Silva ◽  
Yollanda Edwirges Moreira Franco ◽  
Giovanna Barbarini Longato
Keyword(s):  
Literature Review ◽  
Therapeutic Potential ◽  
Review Article ◽  
In Vivo Studies ◽  
Exclusion Criteria ◽  
Asian Continent ◽  
Natural Origin ◽  
Beneficial Effects

Natural products have been used by humanity for many centuries to treat various illnesses and with the advancement of technology, it became possible to isolate the substances responsible for the beneficial effects of these products, as well as to understand their mechanisms. In this context, myristicin, a substance of natural origin, has shown several promising activities in a large number of in vitro and in vivo studies carried out. This molecule is found in plants such as nutmeg, parsley, carrots, peppers, and several species endemic to the Asian continent. The purpose of this review article is to discuss data published in the last 10 years at Pubmed, Lilacs and Scielo databases, reporting beneficial effects, toxicity and promising data of myristicin for its future use in medicine. From 94 articles found in the literature, 68 were included. Exclusion criteria took into account articles whose tested extracts did not have myristicin as one of the major compounds.

scholarly journals The Changing Face of in vitro Culture Models for Thyroid Cancer Research: A Systematic Literature Review

2020 ◽  
Vol 7 ◽  
Author(s):  
Dylan Chew ◽  
Victoria Green ◽  
Andrew Riley ◽  
Richard James England ◽  
John Greenman
Keyword(s):  
Cancer Research ◽  
Thyroid Cancer ◽  
Literature Review ◽  
In Vitro Culture ◽  
Systematic Literature Review ◽  
Culture Models

scholarly journals Can Anorectal Atresia Be Diagnosed in the First Trimester of Pregnancy? A Systematic Literature Review

Medicina ◽  
2020 ◽  
Vol 56 (11) ◽  
pp. 583
Author(s):  
Liana Ples ◽  
Radu Chicea ◽  
Mircea-Octavian Poenaru ◽  
Adrian Neacsu ◽  
Romina Marina Sima ◽  
...  
Keyword(s):  
Literature Review ◽  
Systematic Literature Review ◽  
First Trimester ◽  
Vitro Fertilization ◽  
Detailed Evaluation ◽  
First Trimester Of Pregnancy ◽  
Anorectal Atresia ◽  
Abdominal Cyst ◽  
First Trimester Scan

Anorectal atresia (ARA) is a common congenital anomaly, but prenatal diagnosis is difficult, late, and unspecific. Utilizing a case of a 46 year old primipara with an egg donation In Vitro Fertilization (IVF) pregnancy, diagnosed at the first trimester scan with an anechoic isolated structure, which indicates anal atresia, we performed a systematic literature review in order to evaluate early prenatal ARA diagnosis. A total of 16 cases were reported as first trimester ARA suspicion, and only three had no associated anomalies. The most frequent ultrasound (US) sign was the presence of a cystic, anechoic pelvic structure of mainly tubular shape, or a plain abdominal cyst. In the majority of cases, structures were thin-walled and delimitated from the bladder. The presence of hyperechoic spots signifying enterolithiasis and peristaltic movements were helpful in order to establish the bowel origin of the lesion. Considering the high eventuality that the lesion is transitory, meaning later in pregnancy the fetus looks normal, early detection of such a sign should prompt further structural detailed evaluation, karyotyping, and appropriate pregnancy and postnatal counselling.

Removal of obturation material in endodontic retreatment: a literature review

RSBO ◽  
2019 ◽  
Vol 16 (2) ◽  
pp. 109
Author(s):  
Carina Do Nascimento Menezes ◽  
Verydianna Frota Carneiro ◽  
Mônica Sampaio do Vale
Keyword(s):  
Literature Review ◽  
Latin American ◽  
Root Canal ◽  
Ex Vivo ◽  
Filling Material ◽  
Advantages And Disadvantages ◽  
In Vivo Experiments ◽  
Automated Method

Introduction: Removal of filling material from the root canal system is required when a previous endodontic treatment fails, what may result in the permanence of an unfavorable periapical condition. The intent is to completely remove the filling material inside of the root canal to achieve sufficient cleaning and shaping for successful retreatment. Objective: The aims of this article were to provide asystematic review of the different techniques of endodontic filling material associated or not with organic solvents and to analyze them critically in terms of advantages and disadvantages of each technique. Literature review: The descriptors used were “guttapercha”, “obturation,” and “retreatment” in the following databases: PubMed, MEDLINE, Latin American and Caribbean Center on Health Sciences Information (Bireme), Latin-American and CaribbeanHealth Sciences (Lilacs), Brazilian Dentistry Bibliography (BBO), and Scientific Electronic Library Online (SciELO). Publications of in vitro/ ex vivo and in vivo experiments without language restriction between the years 2010 and 2018 were selected. Conclusion: None of the techniques were capable of performing complete root canal cleaning, and the manual method was so effective as the automated method, although it requires longer working time. Furthermore, although this review confirmed that the solvent action did not allow a significantimprovement in the removal of the filling material, ultrasoundactivated irrigation proved to be an efficient adjunctive device as it could significantly reduce the volume of intracanal residuals.

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