The long-term effects of tourist policy adjustments on the development of tourism in Taiwan: Consideration of time trends and Fourier component test results

2017 ◽  
Vol 19 (3) ◽  
pp. 349-357 ◽  
Author(s):  
Fang-Mei Tseng ◽  
Wen-Chou Huang
Keyword(s):  
Time Trends ◽  
Fourier Component ◽  
Test Results ◽  
Long Term Effects ◽  
Component Test ◽  
Policy Adjustments

Challenges to Overcome and Scaffolding to Build on

2019 ◽  
Vol 9 (3) ◽  
pp. 50-67
Author(s):  
Hao Yang ◽  
Zhiqiang Ma
Keyword(s):  
Teacher Perceptions ◽  
Flipped Classroom ◽  
Public University ◽  
Test Results ◽  
Learning Behavior ◽  
Long Term Effects ◽  
Exploratory Case Study ◽  
Flipped Classrooms

While current research on the flipped classroom generally focuses on test results and (or) student/teacher perceptions as a measurement of its pedagogical efficacy, students' adaptation to it and the essential conditions for its application are rarely explored. This exploratory case study aims to rectify this by examining how university students adapted to flipped classrooms implemented in a public university in East China. The findings suggest that while the flipped model is impeded by entrenched polarity between students in terms of their learning dispositions and academic competence, students do develop a prototype of theories of learning, a sense of better self through learning from their peers and an awareness of the importance of intrinsic motivation. A gradualist approach is thus proposed for implementing flipped classrooms, which requires longitudinal studies accordingly to understand its long-term effects on learning behavior hitherto left unexplored.

Effects of Post-Tightening on the Residual Bolt Force and the Sealing Performance of Flanged Connections With PTFE Gaskets (Long Term Effects at Room Temperature)

2011 ◽  
Author(s):  
Taiki Hagiri ◽  
Takashi Kobayashi ◽  
Kengou Nishiura ◽  
Kazuaki Uchiyama
Keyword(s):  
Room Temperature ◽  
Test Results ◽  
Long Term Effects ◽  
Viscoelastic Characteristic ◽  
Sealing Performance ◽  
Nominal Size ◽  
Gasket Material

It is known that bolt forces reduce significantly after tightening bolted flanged connections in which expanded PTFE gaskets are used. Bolts are often post-tightened in practice after a while to compensate for the reduction of bolt forces. The viscoelastic characteristic of expanded PTFE gaskets is the main cause for the phenomenon. However, the long term effects of the post-tightening on the residual bolt forces and the sealing performance of flanged connections have not been clarified yet. In this study, two sets of flanged connections (2 inch in nominal size), in which PTFE gaskets were used, were prepared and tightened. One of the flanges was post-tightened after a designated time. The reduction of bolt forces and the change in the sealing performance were measured for about two months. The results were compared with those of flanges without post-tightening. Based on the test results, the effectiveness of post-tightening was discussed from the viewpoint of the residual bolt force and the sealing performance. It has been clarified that the effectiveness of post-tightening depends on gasket material and that post-tightening is effective for expanded PTFE gaskets.

scholarly journals Indicators of COVID-19 status in a cohort study of university staff and post-graduate research students, including results from home antibody testing

2020 ◽  
Author(s):  
Katrina A. S. Davis ◽  
Ewan Carr ◽  
Daniel Leightley ◽  
Valentina Vitiello ◽  
Gabriella Bergin-Cartwright ◽  
...  
Keyword(s):  
Cohort Studies ◽  
Antibody Test ◽  
Self Report ◽  
Test Results ◽  
Long Term Effects ◽  
Antibody Testing ◽  
Postgraduate Students ◽  
Research Students ◽  
Core Symptoms

AbstractBackgroundCohort studies of people with a history of COVID-19 infection and controls will be essential to understand the epidemiology of long-term effects. However, clinical diagnosis requires resources that are frequently restricted to the severely ill. Cohort studies may have to rely on surrogate indicators of COVID-19 illness. We describe the prevalence and overlap of five potential indicators: self-reported suspicion, self-reported core symptoms, symptom algorithm, self-reported routine test results, and home antibody testing.MethodsAn occupational cohort of staff and postgraduate students at a large London university who participated in surveys and antibody testing. Self-report items cover March to June 2020 and antibody test results from ‘lateral flow’ IgG/IgM antibody test cassettes sent to participants in June 2020.ResultsValid antibody test results were returned for 1882 participants. Of the COVID-19 indicators, the highest prevalence was core symptoms (770 participants positive, 41%), followed by participant suspicion of infection (n=509, 27%), a symptom algorithm (n=297, 16%), study antibody positive test (n=124, 6.6%) and self-report of a positive external test (n=39, 2.1%). Study antibody positive result was rare in people who had no suspicion they had experienced COVID-19 (n=4, 0.7%) or did not experience core symptoms (n=10, 1.6%). When study antibody test results were compared with earlier external antibody results in those who had reported them, the study antibody results agreed in 88% cases (kappa= 0.636), with a lower proportion testing positive on this occasion (proportion with antibodies detected 15% in study test vs 24% in external testing).DiscussionOur results demonstrate that there is some agreement between different COVID indicators, but that they a more complete story when used together. Antibody testing may provide greater certainty and be one of the only ways to detect asymptomatic cases, but is likely to under-ascertain due to weak antibody responses to mild infection, which wane over time. Cohort studies will need to review how they deal with different and sometimes conflicting indicators of COVID-19 illness in order to study the long-term outcomes of COVID-19 infection and related impacts.What is already known on this subject?Research into the effects of COVID-19 in the community is needed to respond to the pandemic. Objective testing has not been widely available and accuracy may not be high when carried out in retrospect. Many cohort studies are considering how best to measure COVID-19 infection status.What this study adds?Antibody testing is feasible, but it is possible that sensitivity may be poor. Each indicator included added different aspects to the ascertainment of COVID-19 exposure. Using combinations of self-reported and objectively measured variables, it may be possible to tailor COVID-19 indicators to the situation.

Space-exposed seed experiment developed for students

1992 ◽  
Vol 50 (1) ◽  
pp. 860-861
Author(s):  
Donna Leeper ◽  
Kelvin Bridgers ◽  
Ernest C. Hammond
Keyword(s):  
The United States ◽  
Test Results ◽  
Long Term Effects ◽  
The Earth ◽  
Long Duration ◽  
Foreign Countries ◽  
Abundant Supply ◽  
Germination And Growth ◽  
To Receive

The SEEDS project was flown in orbit aboard the Long Duration Exposure (LDEF) for nearly six years. During this time in space, the tomato seeds received an enormously abundant supply of cosmic radiation. Upon the return of the LDEF to earth, the SEEDS project was distributed throughout the United States and 30 foreign countries for analysis. The purpose of the experiment was to determine the long term effects of cosmic rays on living tissue. At Morgan, the analysis performed varied from germination and growth rates to electron microscopy and x ray analysis.In analyzing the seeds under the electron microscope, usual observations were performed on the nutritional and epidermic layers of the seed. These layers appeared to be more porous in the space-exposed seeds than in the Earth-based control seeds. This unusual characteristic may explain the increase in the space seeds’ growth pattern. (Several test results show that the space-exposed seeds germinate sooner than the Earth-based seeds. Also, the space exposed seeds are growing at a faster rate.) The porous nutritional region may allow the the seeds to receive necessary nutrients and liquids more readily. Thus, enabling the plant to grow at a much faster rate.

Deterrence or Brutalization

1980 ◽  
Vol 26 (4) ◽  
pp. 453-484 ◽  
Author(s):  
William J. Bowers ◽  
Glenn L. Pierce
Keyword(s):  
New York ◽  
Capital Punishment ◽  
Time Trends ◽  
Human Life ◽  
New York State ◽  
Long Term Effects ◽  
Short Term ◽  
Mass Murders ◽  
Effects Of War

In this study, we find that in New York State over the period 1907-63 there were, on the average, two additional homicides in the month after an execution. Controls for time trends, seasonality, the effects of war, and adjustments for autocorrelation tend to confirm this finding. Such a "brutalizing" effect of executions is consistent with research on violent events such as publicized suicides, mass murders, and assassinations; with previous studies of the long-term effects of the availability and use of capital punishment; and with a small number of investigations of the short-term impact of executions in the days, weeks, and months that fol low. This suggests that the message of executions is one of "lethal ven geance" more than deterrence. The resulting sacrifice of human life chal lenges the constitutionality of capital punishment.

scholarly journals Expression of SSTR2a, but not of SSTRs 1, 3, or 5 in Somatotroph Adenomas Assessed by Monoclonal Antibodies Was Reduced by Octreotide and Correlated With the Acute and Long-Term Effects of Octreotide

2013 ◽  
Vol 98 (11) ◽  
pp. E1730-E1739 ◽  
Author(s):  
Olivera Casar-Borota ◽  
Ansgar Heck ◽  
Stefan Schulz ◽  
Jahn Marthin Nesland ◽  
Jon Ramm-Pettersen ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Medical Treatment ◽  
Somatostatin Receptors ◽  
Immunohistochemical Analysis ◽  
Test Dose ◽  
Test Results ◽  
Long Term Effects ◽  
Pretreated Group ◽  
Octreotide Treatment

Context: Reduced expression of somatostatin receptors (SSTRs) in somatotroph adenomas and their potential down-regulation after medical treatment may explain the unsatisfactory response to octreotide in particular acromegalic patients. The expression of SSTRs other than SSTR2a has not been studied in large, unselected cohorts using novel rabbit monoclonal antibodies. Objective: We aimed to determine the expression of SSTRs 1, 2a, 3, and 5 in somatotroph adenomas, to correlate expression with clinical characteristics and the response to octreotide, and to ascertain whether preoperative octreotide treatment affected SSTR expression. Design, Setting, Patients: The study included 78 adenomas from patients operated on consecutively during 2000 to 2010. After exclusion of 13 patients, immunohistochemical analysis with rabbit monoclonal antibodies against SSTRs 1, 2a, 3, and 5 (clones UMB-7, -1, -5, and -4) was performed on 65 adenomas. Intervention: Twenty-eight patients received preoperative octreotide, and 37 patients were operated on without pretreatment. Twenty-six patients were randomized to direct surgery (n = 13) or to octreotide pretreatment (n = 13). Main Outcome Measure: SSTR expression was evaluated using a 12-grade scoring system. The responses to the octreotide test dose (GH reduction) and to 6 months of octreotide (IGF-I reduction) were measured. Results: The majority of adenomas showed membranous expression of SSTRs 2a and 5. SSTR2a expression was reduced in the pretreated group and correlated with the acute octreotide test results and the effect of octreotide treatment. In a linear regression model with SSTR2a expression as the determinant, the correlation with the acute test response improved after adjustment for medical pretreatment. Conclusion: Rabbit monoclonal antibodies are reliable markers of SSTRs in somatotroph adenomas. SSTR2a expression correlated with the response to octreotide and was reduced after octreotide treatment, indicating the need for adjustment when SSTR2a expression is correlated with baseline characteristics. Evaluation of SSTR subtypes may be an important aspect of improving the medical treatment for acromegaly.

scholarly journals Immediate and Long-Term Effects of “Learning By Teaching” on Knowledge of Cognition

2017 ◽  
Vol 6 (4) ◽  
pp. 1 ◽  
Author(s):  
Mary Gutman
Keyword(s):  
Procedural Knowledge ◽  
Test Results ◽  
Long Term Effects ◽  
Face To Face ◽  
Learning By Teaching ◽  
Dependent Variables ◽  
Post Test ◽  
Dual Perspective ◽  
Practical Implications

Learning By Teaching (LBT) programs for pre-service teachers in two different environments (technological and face-to-face) were compared using 100 pre-service teachers as subjects. Both programs were based on the IMPROVE instructional method which provides explicit metacognitive steps for LBT with a dual perspective (2P): that of the teacher and that of the learner. The dependent variables Knowledge of Cognition (KC) in learning and in teaching were tested for their immediate and long-term effects in a Technology-Based System group (TBS+2P), and in a Face-to-Face group (F2F+2P). Post-test results of KC have indicated that the TBS+2P group had shown a higher level of conditional and procedural knowledge of teaching. The TBS+2P group has also performed better in measures of long-term effects of declarative knowledge in teaching. Both theoretical and practical implications of this study are discussed.

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

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