scholarly journals Erythrocyte linoleic acid, but not oleic acid, is associated with improvements in body composition in men and women

2016 ◽  
Vol 60 (5) ◽  
pp. 1206-1212 ◽  
Author(s):  
Martha A. Belury ◽  
Rachel M. Cole ◽  
Brittney E. Bailey ◽  
Jia-Yu Ke ◽  
Rebecca R. Andridge ◽  
...  
2016 ◽  
Vol 60 (5) ◽  
pp. NA-NA
Author(s):  
Martha A. Belury ◽  
Rachel M. Cole ◽  
Brittney E. Bailey ◽  
Jia-Yu Ke ◽  
Rebecca R. Andridge ◽  
...  

2007 ◽  
Vol 97 (5) ◽  
pp. 1001-1011 ◽  
Author(s):  
Estelle V. Lambert ◽  
Julia H. Goedecke ◽  
Kerry Bluett ◽  
Kerry Heggie ◽  
Amanda Claassen ◽  
...  

The aim of this study was to measure the effects of 12 weeks of conjugated linoleic acid (CLA) supplementation on body composition, RER, RMR, blood lipid profiles, insulin sensitivity and appetite in exercising, normal-weight persons. In this double-blind, randomised, controlled trial, sixty-two non-obese subjects (twenty-five men, thirty-seven women) received either 3·9 g/d CLA or 3·9 g high-oleic acid sunflower oil for 12 weeks. Prior to and after 12 weeks of supplementation, oral glucose tolerance, blood lipid concentrations, body composition (dual-energy X-ray absorptiometry and computerised tomography scans), RMR, resting and exercising RER and appetite were measured. There were no significant effects of CLA on body composition or distribution, RMR, RER or appetite. During the oral glucose tolerance tests, mean plasma insulin concentrations (0, 30, 120 min) were significantly lower (P = 0·04) in women who supplemented with CLA (24·3 (sd9·7) to 20·4 (sd8·5) μU/ml) compared to high-oleic acid sunflower oil control (23·7 (sd9·8) to 26·0 (sd8·8) μU/ml). Serum NEFA levels in response to oral glucose were attenuated in both men and women in the CLA (P = 0·001) compared to control group. However, serum total cholesterol and LDL-cholesterol concentrations decreased in both groups and HDL-cholesterol concentrations decreased in women over 12 weeks (P = 0·001,P = 0·02,P = 0·02, respectively). In conclusion, mixed-isomer CLA supplementation had a favourable effect on serum insulin and NEFA response to oral glucose in non-obese, regularly exercising women, but there were no CLA-specific effects on body composition, energy expenditure or appetite.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 618-618
Author(s):  
Rachel Cole ◽  
Austin Angelotti ◽  
Martha Belury

Abstract Objectives Higher blood levels of the essential fatty acid, linoleic acid (LA), are associated with a decreased risk of type 2 diabetes.  However, many dietary oils once high in LA are now low in LA and high in oleic acid (OA).  We have previously shown in healthy adults that supplementation with a high LA oil can increase plasma LA levels and decrease plasma OA levels.  The current study examines the relationship of habitual levels of plasma LA and OA with markers of body composition, inflammation and glycemia in healthy adults. Methods Data from baseline visit were analyzed from 127 health adults participating in a 2-week study of the effect of dietary oils on blood fatty acid profiles.  Plasma fatty acid composition was measured by gas chromatography. Insulin, glucose, total and high molecular weight (HMW) adiponectin, tumor necrosis factor receptor 2 (TNF-r2) and lipopolysaccharide binding protein (LBP) were measured in fasting plasma samples.  Body mass index (BMI) and sagittal diameter (SAD) were measured as markers of body composition.  Grip strength was measured as a marker of muscle strength and gait speed was measured as a marker of muscle function.  Linear regression was used to assess the association of study measurements to plasma LA or OA.  Results were adjusted for sex, age, physical activity and BMI. Results Plasma LA was negatively associated with both BMI and SAD while plasma OA was positively associated with both insulin and grip strength.  In males, but not females, higher plasma LA was associated with higher HMW adiponectin while higher plasma OA was positively associated with fasting glucose.  Neither plasma LA or OA were associated with total adiponectin, TNF-r2, LBP or gait speed. Conclusions Higher levels of plasma LA predicted for lower measures of adiposity in both males and females and higher HMW adiponectin levels in males. Higher levels of plasm OA predicted for increased grip strength and higher glycemia, particularly in men.  To our knowledge no randomized controlled trial has compared LA or OA supplementation on body composition, glycemia, and adiponectin in healthy men and women. Funding Sources Funding was provided by the Carol S. Kennedy Professorship and the Ohio Agriculture Research and Development Center.


2001 ◽  
Vol 16 (11) ◽  
pp. 2142-2151 ◽  
Author(s):  
S. M. F. Pluijm ◽  
M. Visser ◽  
J. H. Smit ◽  
C. Popp-Snijders ◽  
J. C. Roos ◽  
...  

2004 ◽  
Vol 164 (2) ◽  
pp. 210 ◽  
Author(s):  
Nicholas P. Hays ◽  
Raymond D. Starling ◽  
Xiaolan Liu ◽  
Dennis H. Sullivan ◽  
Todd A. Trappe ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Chunying Yang ◽  
Xueming Liu ◽  
Zhiyi Chen ◽  
Yaosheng Lin ◽  
Siyuan Wang

The oil contents and fatty acid (FA) compositions of ten new and one wildCamellia oleiferavarieties were investigated. Oil contents in camellia seeds from newC. oleiferavaried with cultivars from 41.92% to 53.30% and were affected by cultivation place. Average oil content (47.83%) of dry seeds from all ten new cultivars was almost the same as that of wild commonC. oleiferaseeds (47.06%). NewC. oleiferacultivars contained similar FA compositions which included palmitic acid (C16:0, PA), palmitoleic acid (C16:1), stearic acid (C18:0, SA), oleic acid (C18:1, OA), linoleic acid (C18:2, LA), linolenic acid (C18:3), eicosenoic acid (C20:1), and tetracosenoic acid (C24:1). Predominant FAs in mature seeds were OA (75.78%~81.39%), LA (4.85%~10.79%), PA (7.68%~10.01%), and SA (1.46%~2.97%) and OA had the least coefficient of variation among different new cultivars. Average ratio of single FA of ten artificialC. oleiferacultivars was consistent with that of wild commonC. oleifera. All cultivars contained the same ratios of saturated FA (SFA) and unsaturated FA (USFA). Oil contents and FA profiles of new cultivars were not significantly affected by breeding and selection.


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