Halophytes as a Potential Resource for Phytodesalination

The purpose of the article is to analyze and substantiate the development of tourism business in Ukraine as a priority component of the national economy. The methodology of this study is to use analytical, spatial, geographical, cultural and other methods. This methodological approach provided an opportunity to carry out a complete analysis of the state of the tourism industry of the state and to draw some conclusions.The scientific novelty lies in the coverage of the real and potential resource potential for the development of the recreational and tourism sphere in Ukraine, detailing the measures for the country ‘s entry into the world tourist market. Conclusions. Analyzing the state and prospects of tourism business development in Ukraine, it should be noted that this industry is one of the priority areas for improving the economy of the country. Historical, cultural – ethnographic, gastronomic, sanatorium and resort potentials of the country will lead the country into world leaders of the tourism industry when creating favorable conditions for investment and proper marketing.

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The Historicity of Jesus and the Potential Resource of the Apocryphal Gospel

The Society of Theology and Thought ◽

10.21731/ctat.2019.82.107 ◽

2019 ◽

pp. 107-150

Author(s):

Hyekyoung Song

Keyword(s):

Potential Resource

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Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors

Molecules ◽

10.3390/molecules25092174 ◽

2020 ◽

Vol 25 (9) ◽

pp. 2174 ◽

Cited By ~ 5

Author(s):

Annalisa Maruca ◽

Delia Lanzillotta ◽

Roberta Rocca ◽

Antonio Lupia ◽

Giosuè Costa ◽

...

Keyword(s):

Essential Oils ◽

Binding Affinity ◽

Structural Changes ◽

Kinase Inhibitors ◽

Synergistic Effects ◽

Data Bank ◽

Binding Modes ◽

Starting Point ◽

Target Action ◽

Potential Resource

Essential oils (EOs) are popular in aromatherapy, a branch of alternative medicine that claims their curative effects. Moreover, several studies reported EOs as potential anti-cancer agents by inducing apoptosis in different cancer cell models. In this study, we have considered EOs as a potential resource of new kinase inhibitors with a polypharmacological profile. On the other hand, computational methods offer the possibility to predict the theoretical activity profile of ligands, discovering dangerous off-targets and/or synergistic effects due to the potential multi-target action. With this aim, we performed a Structure-Based Virtual Screening (SBVS) against X-ray models of several protein kinases selected from the Protein Data Bank (PDB) by using a chemoinformatics database of EOs. By evaluating theoretical binding affinity, 13 molecules were detected among EOs as new potential kinase inhibitors with a multi-target profile. The two compounds with higher percentages in the EOs were studied more in depth by means Induced Fit Docking (IFD) protocol, in order to better predict their binding modes taking into account also structural changes in the receptor. Finally, given its good binding affinity towards five different kinases, cinnamyl cinnamate was biologically tested on different cell lines with the aim to verify the antiproliferative activity. Thus, this work represents a starting point for the optimization of the most promising EOs structure as kinase inhibitors with multi-target features.

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Aging Without Children: The Link between Parental Status and Tangible Support

Journal of Family Issues ◽

10.1177/0192513x21993203 ◽

2021 ◽

pp. 0192513X2199320

Author(s):

Agnete Aslaug Kjær ◽

Anu Siren

Keyword(s):

Later Life ◽

Policy Implications ◽

Living Alone ◽

Parental Status ◽

Older Individuals ◽

Care And Support ◽

Major Disadvantage ◽

Potential Resource ◽

Tangible Support ◽

Negative Link

Having children is a potential resource for care and support in later life. However, whether and, if so, under what conditions, childless older individuals risk insufficient support remains unclear. Using the Danish Longitudinal Study of Ageing (2017), restricted to respondents aged 67 years to 97 years ( n = 5,006), our study analyzes the link between availability of tangible support and parental status in a Nordic welfare state. Our results confirm a negative link between childlessness and support mainly among unpartnered individuals. This combined disadvantage is stronger among men than among women, and the support gap intensifies with increased health needs. Taken together, although childlessness in itself is no major disadvantage for support in late life, childless men living alone risk insufficient support, particularly when in poor health. Our findings have important policy implications for future cohorts of older individuals, who will have less access to support from either a spouse or children.

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Mechanism and Influencing Factors of REY Enrichment in Deep-Sea Sediments

Minerals ◽

10.3390/min11020196 ◽

2021 ◽

Vol 11 (2) ◽

pp. 196

Author(s):

Jiangbo Ren ◽

Yan Liu ◽

Fenlian Wang ◽

Gaowen He ◽

Xiguang Deng ◽

...

Keyword(s):

Deep Sea ◽

Research Progress ◽

Bottom Current ◽

Knowledge Map ◽

P2o5 Content ◽

Deep Sea Sediments ◽

Potential Resource ◽

And Migration ◽

Adsorption Desorption ◽

Sediment Interface

Deep-sea sediments with high contents of rare-earth elements and yttrium (REY) are expected to serve as a potential resource for REY, which have recently been proved to be mainly contributed by phosphate component. Studies have shown that the carriers of REY in deep-sea sediments include aluminosilicate, Fe-Mn oxyhydroxides, and phosphate components. The ∑REY of the phosphate component is 1–2 orders of magnitude higher than those of the other two carriers, expressed as ∑REY = 0.001 × [Al2O3] − 0.002 × [MnO] + 0.056 × [P2O5] − 32. The sediment P2O5 content of 1.5% explains 89.1% of the total variance of the sediment ∑REY content. According to global data, P has a stronger positive correlation with ∑REY compared with Mn, Fe, Al, etc.; 45.5% of samples have a P2O5 content of less than 0.25%, and ∑REY of not higher than 400 ppm. The ∑REY of the phosphate component reaches n × 104 ppm, much higher than that of marine phosphorites and lower than that of REY-phosphate minerals, which are called REY-rich phosphates in this study. The results of microscopic observation and separation by grain size indicate that the REY-rich phosphate component is mainly composed of bioapatite. When ∑REY > 2000 ppm, the average CaO/P2O5 ratio of the samples is 1.55, indicating that the phosphate composition is between carbonate fluoroapatite and hydroxyfluorapatite. According to a knowledge map of sediment elements, the phosphate component is mainly composed of P, Ca, Sr, REY, Sc, U, and Th, and its chemical composition is relatively stable. The phosphate component has a negative Ce anomaly and positive Y anomaly, and a REY pattern similar to that of marine phosphorites and seawater. After the early diagenesis process (biogeochemistry, adsorption, desorption, transformation, and migration), the REY enrichment in the phosphate component is completed near the seawater/sediment interface. In the process of REY enrichment, the precipitation and enrichment of P is critical. According to current research progress, the REY enrichment is the result of comprehensive factors, including low sedimentation rate, high ∑REY of the bottom seawater, a non-carbonate depositional environment, oxidation conditions, and certain bottom current conditions.

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Cylindromicin from Arctic-Derived Fungus Tolypocladium sp. SCSIO 40433

Molecules ◽

10.3390/molecules26041080 ◽

2021 ◽

Vol 26 (4) ◽

pp. 1080

Author(s):

Imran Khan ◽

Jing Peng ◽

Zhuangjie Fang ◽

Wei Liu ◽

Wenjun Zhang ◽

...

Keyword(s):

Secondary Metabolites ◽

Nuclear Overhauser Effect ◽

Inhibition Activity ◽

Tyrosinase Inhibition ◽

Bioactive Natural Products ◽

Chemical Structures ◽

Overhauser Effect ◽

Spectroscopic Analyses ◽

Potential Resource ◽

Nuclear Overhauser

The fungus strain SCSIO 40433 was isolated from an Arctic-derived glacier sediment sample and characterized as Tolypocladium cylindrosporum. A new compound, cylindromicin (1), and seven known secondary metabolites (2–8) were isolated from this strain. The chemical structures of these compounds were elucidated by comprehensive spectroscopic analyses. Cylindromicin (1) featured a 3,4-dihydro-2H-pyran skeleton. The absolute configuration of compound 1 was assigned via interpretation of key Nuclear Overhauser Effect Spectroscopy (NOESY) correlations and Electronic Circular Dichroism (ECD) calculation. Cylindromicin (1) exhibited significant tyrosinase inhibition activity. This study highlights Polar fungi as a potential resource for new bioactive natural products.

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Preparation of Antioxidant and Antibacterial Chitosan Film from Periplaneta americana

Insects ◽

10.3390/insects12010053 ◽

2021 ◽

Vol 12 (1) ◽

pp. 53

Author(s):

Sicong Chen ◽

Xunfan Wei ◽

Zhuoxiao Sui ◽

Mengyuan Guo ◽

Jin Geng ◽

...

Keyword(s):

Food Packaging ◽

Periplaneta Americana ◽

Uv Light ◽

Radical Scavenging ◽

Chitosan Film ◽

American Cockroach ◽

Raw Material ◽

Potential Resource ◽

Radical Scavenging Ability ◽

Dpph Radical Scavenging

Among different insects, the American cockroach (Periplaneta americana) has been bred in industrial scale successfully as a potential resource of protein, lipid, and antibacterial peptide. However, the application of its chitosan has not been studied widely, which has hindered the sufficient utilization of P. americana. In this paper, the chitosan from P. americana was separated, characterized, and processed into film (PaCSF) to examine its potential of being applied in food packaging. As the results of different characterizations showed, PaCSF was similar to shrimp chitosan film (SCSF). However, concerning the performances relating to food packaging, the two chitosan films were different. PaCSF contained more water (42.82%) than SCSF did, resulting in its larger thickness (0.08 mm). PaCSF could resist UV light more effectively than SCSF did. Concerning antioxidant activity, the DPPH radical scavenging ability of PaCSF increased linearly with time passing, reaching 72.46% after 8 h, which was better than that of SCSF. The antibacterial activity assay exhibited that PaCSF resisted the growth of Serratia marcescens and Escherichia coli more effectively than SCSF did. The results implied that P. americana chitosan could be a potential raw material for food packaging, providing a new way to develop P. americana.

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Prevalence and Phenomenology of Sensory Experiences of a Deceased Spouse: A Survey of Bereaved Older Adults

OMEGA - Journal of Death and Dying ◽

10.1177/00302228211016224 ◽

2021 ◽

pp. 003022282110162

Author(s):

Karina S. Kamp ◽

Edith Maria Steffen ◽

Andrew Moskowitz ◽

Helle Spindler

Keyword(s):

Older Adults ◽

Clinical Practice ◽

Late Life ◽

Danish Population ◽

Sensory Experiences ◽

Grief Process ◽

Sensory Modalities ◽

Potential Resource

Sensory and quasi-sensory experiences of the deceased (SED), also called bereavement hallucinations, are common in bereavement, but research detailing these experiences is limited. Methods: An in-depth survey of SED was developed based on existing research, and 310 older adults from the general Danish population participated in the study 6–10 months after their spouse died. Results: SED were reported by 42% of the participants with wide-ranging phenomenological features across sensory-modalities. In particular, seeing and hearing the deceased spouse was experienced as very similar to the couple’s everyday contacts before death. SED were endorsed as positive by a majority of experiencers, and the experiences were often shared with family and friends. Discussion: SED are conceptualized as social and relational phenomena, which may comfort the surviving spouse in late-life bereavement, but also provide tangible help to some experiencers. In clinical practice, SED may be considered a potential resource for the therapeutic grief process.

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