Cultivation of Malassezia furfur, etiological agent of pityriasis (tinea) versicolor

1938 ◽  
Vol 1 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Morris Moore
2021 ◽  
Vol 5 (1) ◽  
pp. 46-53
Author(s):  
Hepni Hepni

Bawang putih selain dikenal sebagai salah satu bumbu dapur dan dipercaya juga sebagai antibiotik dan antifungi. Khasiat ini disebabkan oleh zat allicin yang kandungannya mampu membunuh jamur dan bakteri. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh perbedaan konsentrasi ekstrak bawang putih terhadap zona hambat pertumbuhan jamur Malassezia furfur penyebab penyakit panu (Tinea versicolor), dengan menggunakan metode studi literatur. Teknik pengambilan sampel yang digunakan yaitu purposive sampling dan memperoleh 2 sampel yaitu berupa jurnal dan Karya Tulis Ilmiah yang membahas tentang pengaruh bawang putih dalam mengatasi penyakit panu. Senyawa yang ada pada bawang putih adalah allicinn yang didapatkan dari ekstrak bawang putih yang mempunyai aktivitas dan daya hambat terhadap jamur Malassezia furfur penyebab penyakit panu. Dengan hasil yang didapatkan semakin tinggi konsentrasi ekstrak bawang putih maka semakin luas zona hambat pertumbuhan jamur penyebab panu.


PEDIATRICS ◽  
1985 ◽  
Vol 76 (6) ◽  
pp. 896-900
Author(s):  
John G. Long ◽  
Harry L. Keyserling

Malassezia furfur (Pityrosporum orbiculare, P ovals), a lipophilic yeast that is part of the normal skin flora, causes tinea versicolor but has only rarely been associated with more serious infections. We report five episodes in four infants of catheter-related infection caused by this organism. All episodes occurred in infants who had survived serious neonatal disorders and were receiving prolonged therapy with intravenous fat emulsion. Sudden onset of fever without focal findings was the usual presentation; however, one afebrile patient had recurrent episodes of apnea, bradycardia, and cyanosis. Thrombocytopenia was a prominent finding. Patients were generally treated with amphotericin B. All patients recovered when the colonized catheter was removed or fat emulsion therapy was stopped. The yeast usually grew slowly in blood culture media but grew readily when subcultured onto Sabouraud's medium coated with sterile olive oil. Yeasts were readily identified in all four patients in whom a buffy coat Gram stain was obtained of blood from the central intravenous catheter. M furfur may be a fairly common but unrecognized cause of catheter-related sepsis in infants receiving long-term fat emulsion therapy. This organism should be sought whenever routine blood cultures are negative for bacteria and yeasts are observed in a buffy coat Gram stain.


1968 ◽  
Vol 6 (9) ◽  
pp. 35-36

The treatment of fungal infections (‘ringworm’ or ‘tinea’) of the skin, hair and finger nails has been revolutionised by griseofulvin given orally. This drug is mainly needed to treat small-spore and favus infections of the scalp, and Trichophyton rubrum infections of the skin and fingernails, since this organism is very resistant to topical applications. Griseofulvin does not cure T. rubrum infections of the toenails; it is generally not needed for minor infections with organisms other than T. rubrum, and it has little effect on toe-web infection. Griseofulvin is ineffective in tinea versicolor (caused by Malassezia furfur), and infections by the yeast-like organism Candida albicans.1


Author(s):  
Ms.Sini Baby ◽  
Dimal Jose ◽  
Agnes K Mathew ◽  
Biniya John ◽  
Antony Varghese Antony

Herbal medicines are gaining more interest both in terms of medicinal and economic benefits and they are getting more patient compliance due to its fewer side effects as compared to allopathic medicines. The present research was aimed at phytochemical screening and antifungal evaluation of rhizomic extract of Zingiber wightianum Thwaites belonging to Zingiberaceae family. The rhizomes were subjected for Soxhlet extraction and the preliminary phytochemical screening of this extract proved the presence of alkaloids, carbohydrates, tannins, flavonoids, saponins, phenols. Subsequently, these extracts were evaluated for antifungal activity and minimum inhibitory concentration was determined. Hence revealed the potential to treat a fungal infection Tinea versicolor, caused by fungus Malassezia furfur. This investigation was also undertaken with a view to formulate and evaluate the herbal gel using Zingiber wightianum rhizomic extract. Thus, the overall studies concluded that the rhizomic extract of Zingiber wightianum Thwaites and its formulation would be a breakthrough in the field of modern antifungal drug.


Author(s):  
K. Devendrappa ◽  
Mohammed Waseem Javed

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Pityriasis versicolor is a superficial fungal infection caused by the polymorphous endogenous yeast <em>Malassezia furfur</em>. Infection typically occurs on the trunk and proximal upper extremities and is characterized by distinctive scaly, coalescent hyperpigmented and/or hypopigmented to erythematous patches. Tinea versicolor is a superficial chronically recurring fungal infection of the stratum corneum, characterized by scaly, hypo and hyperpigmented irregular macules, usually located on the trunk and proximal extremities caused by pityrosporum orbiculare.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">100 patients of untreated tinea versicolor who attended the outpatient department were selected at random irrespective of their age, socioeconomic status, occupation. A detailed history was taken, regarding the age, sex, religion, occupation, socioeconomic status, residence, duration and course of the disease, site of distribution of lesion and any other associated cutaneous and systemic diseases</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">The majority patients i.e. 27 (27%) were students and followed by the unskilled workers who comprised 20% of patients. The incidence is quite low in business and official class 3% and 11% respectively. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">The duration of the disease in 93% of patients was less than 10 years and in 7% the duration was more than 10 years.</span></p>


2020 ◽  
Vol 8 (10) ◽  
pp. 4806-4812
Author(s):  
Sruthi Sreedhar

Skin disorder constitutes one of the largest groups of health problems in general practice. Good skin is an integral part of health. In Ayurveda, all skin diseases are explained under a single heading of Kushta. Sidhma Kushta is an Oupasargikaroga. All Kushta is due to aggravation of Tridosas. These aggravated Dosha vitiates Dushyas like Twak, Raktha, Mamsa and Ambu by circulating in them and produce Vaivarnya.1According to Susrutha, whenever the aggravated Doshas get stagnated, Mandalas appear at that site.2 Kushta are innumerable in number based on the permutation and combination of Doshas and Dushyas, but mainly they are divided into seven Maha Kushta and eleven Kshudra Kushta. Sidhma is a variety of Kushtaroga according to all the authors of Brihathrayi and Laghutrayi. However, Charaka classified it under Maha Kushta and other Acharyas like Susrutha and Vagbhata brought it under Kshudra Kushta. By Dalhana's commentary it can be understood that Sidhma is of two types, Sidhma Kushta and Pushpitha Sidhma.3 Symptoms of Tinea versicolor are similar to that of Lakshanas of Sidhma Kushta, Acharya Susrutha has said that Krimi is also one of the cause for Kushta and Tinea versicolor is a superficial mycoses caused by a fungi called Malassezia furfur. Understanding of Lakshanas and Samprapti plays an important role in the diagnosis, prognosis and treatment of the disease. So, an attempt is made to analyse and understand the concept of Sidhma Kushta.


Author(s):  
Diah Ariana

Tinea versicolor or pitiriasis versicolor is a skin disorder caused by Malassezia furfur infection which is a fungal infection on the skin of the chronic surface. Clinical features is in the form of fine spots that colored white to brown black, this infection is also called a skin fungus with blotches. Treatment of Tinea versicolor can use chemical or traditional medicine. Chemical treatments such as creams or ointments cause sticky taste, while one of the traditional medicine is the bulb and skin of the garlic bulb (Allium sativum Linn) containing allicin substances that are efficacious as an anti-fungal.               This research is an experimental research with the aim to know the difference of inhibition zone to Malessezia furfur fungus. There are 3 treatments with 9 repetitions. The extraction method used is the soxhlet method. Anti-fungal activity test was done by using rating method, Saboroud Dextrose Agar (SDA) media which has been inoculated with suspension of Malassezia furfur with concentration 1.5x108 CFU/ml (Mc Farland standard).               Result of data analysis obtained by ANOVA p = 0,000 < α = 0,05, that there is difference of inhibition zone from treatment of garlic bulb extract and skin of garlic bulb (Allium sativum Linn). It is indicated that there is effect of giving garlic bulb extract (Allium sativum Linn) and garlic bulb skin (Allium sativum Linn) to Malassezia furfur fungus. Further tests were performed to compare mean treatment i.e. HSD test. It was obtained sig (p) 0,016 > α 0,05 which means bulb extract and garlic bulb skin (Allium sativum Linn) have different effect. Keywords: Tinea versicolor, Malassezia furfur, garlic bulb.


Sign in / Sign up

Export Citation Format

Share Document