The experiment by iron ore tailings as the main raw material, add a small amount of fly ash, coal gangue, limestone and biological admixture, the preparation of iron ore tailings bio-ceramic filter material. The effect of the material proportion and sintering temperature and the ball size on the bio-ceramic filter material processing sewage pollutant removal efficiency was investigated. Research shows that the optimal proportion of bio-ceramic is: 86%iron ore tailings, 6% coal gangue, 4% fly ash, 3% limestone, 1% biological admixture. Under the condition of sintering temperature 1100 °C, bio-ceramic size 3 ~ 5 mm, the bio-ceramic filter material of COD removal efficiency 80% and turbidity of sewage 71% respectively. Through bio-ceramic filter material further analysis of XRD and SEM, in the sintering process of minerals such as sodium feldspar, quartz, hematite, together, make bio-ceramic has high strength. Internal porous bio-ceramic surface is rough at the same time, and the specific surface area is larger. Bio-ceramic has good adsorption performance, therefore, is helpful to remove the pollutant in the domestic sewage.