scholarly journals Inverted bell-curve-based ensemble of deep learning models for detection of COVID-19 from chest X-rays

Author(s):  
Ashis Paul ◽  
Arpan Basu ◽  
Mufti Mahmud ◽  
M. Shamim Kaiser ◽  
Ram Sarkar

AbstractNovel Coronavirus 2019 disease or COVID-19 is a viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The use of chest X-rays (CXRs) has become an important practice to assist in the diagnosis of COVID-19 as they can be used to detect the abnormalities developed in the infected patients’ lungs. With the fast spread of the disease, many researchers across the world are striving to use several deep learning-based systems to identify the COVID-19 from such CXR images. To this end, we propose an inverted bell-curve-based ensemble of deep learning models for the detection of COVID-19 from CXR images. We first use a selection of models pretrained on ImageNet dataset and use the concept of transfer learning to retrain them with CXR datasets. Then the trained models are combined with the proposed inverted bell curve weighted ensemble method, where the output of each classifier is assigned a weight, and the final prediction is done by performing a weighted average of those outputs. We evaluate the proposed method on two publicly available datasets: the COVID-19 Radiography Database and the IEEE COVID Chest X-ray Dataset. The accuracy, F1 score and the AUC ROC achieved by the proposed method are 99.66%, 99.75% and 99.99%, respectively, in the first dataset, and, 99.84%, 99.81% and 99.99%, respectively, in the other dataset. Experimental results ensure that the use of transfer learning-based models and their combination using the proposed ensemble method result in improved predictions of COVID-19 in CXRs.

COVID ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 403-415
Author(s):  
Abeer Badawi ◽  
Khalid Elgazzar

Coronavirus disease (COVID-19) is an illness caused by a novel coronavirus family. One of the practical examinations for COVID-19 is chest radiography. COVID-19 infected patients show abnormalities in chest X-ray images. However, examining the chest X-rays requires a specialist with high experience. Hence, using deep learning techniques in detecting abnormalities in the X-ray images is presented commonly as a potential solution to help diagnose the disease. Numerous research has been reported on COVID-19 chest X-ray classification, but most of the previous studies have been conducted on a small set of COVID-19 X-ray images, which created an imbalanced dataset and affected the performance of the deep learning models. In this paper, we propose several image processing techniques to augment COVID-19 X-ray images to generate a large and diverse dataset to boost the performance of deep learning algorithms in detecting the virus from chest X-rays. We also propose innovative and robust deep learning models, based on DenseNet201, VGG16, and VGG19, to detect COVID-19 from a large set of chest X-ray images. A performance evaluation shows that the proposed models outperform all existing techniques to date. Our models achieved 99.62% on the binary classification and 95.48% on the multi-class classification. Based on these findings, we provide a pathway for researchers to develop enhanced models with a balanced dataset that includes the highest available COVID-19 chest X-ray images. This work is of high interest to healthcare providers, as it helps to better diagnose COVID-19 from chest X-rays in less time with higher accuracy.


2022 ◽  
Vol 2161 (1) ◽  
pp. 012078
Author(s):  
Pallavi R Mane ◽  
Rajat Shenoy ◽  
Ghanashyama Prabhu

Abstract COVID -19, is a deadly, dangerous and contagious disease caused by the novel corona virus. It is very important to detect COVID-19 infection accurately as quickly as possible to avoid the spreading. Deep learning methods can significantly improve the efficiency and accuracy of reading Chest X-Rays (CXRs). The existing Deep learning models with further fine tune provide cost effective, rapid, and better classification results. This paper tries to deploy well studied AI tools with modification on X-ray images to classify COVID 19. This research performs five experiments to classify COVID-19 CXRs from Normal and Viral Pneumonia CXRs using Convolutional Neural Networks (CNN). Four experiments were performed on state-of-the-art pre-trained models using transfer learning and one experiment was performed using a CNN designed from scratch. Dataset used for the experiments consists of chest X-Ray images from the Kaggle dataset and other publicly accessible sources. The data was split into three parts while 90% retained for training the models, 5% each was used in validation and testing of the constructed models. The four transfer learning models used were Inception, Xception, ResNet, and VGG19, that resulted in the test accuracies of 93.07%, 94.8%, 67.5%, and 91.1% respectively and our CNN model resulted in 94.6%.


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Mundher Mohammed Taresh ◽  
Ningbo Zhu ◽  
Talal Ahmed Ali Ali ◽  
Asaad Shakir Hameed ◽  
Modhi Lafta Mutar

The novel coronavirus disease 2019 (COVID-19) is a contagious disease that has caused thousands of deaths and infected millions worldwide. Thus, various technologies that allow for the fast detection of COVID-19 infections with high accuracy can offer healthcare professionals much-needed help. This study is aimed at evaluating the effectiveness of the state-of-the-art pretrained Convolutional Neural Networks (CNNs) on the automatic diagnosis of COVID-19 from chest X-rays (CXRs). The dataset used in the experiments consists of 1200 CXR images from individuals with COVID-19, 1345 CXR images from individuals with viral pneumonia, and 1341 CXR images from healthy individuals. In this paper, the effectiveness of artificial intelligence (AI) in the rapid and precise identification of COVID-19 from CXR images has been explored based on different pretrained deep learning algorithms and fine-tuned to maximise detection accuracy to identify the best algorithms. The results showed that deep learning with X-ray imaging is useful in collecting critical biological markers associated with COVID-19 infections. VGG16 and MobileNet obtained the highest accuracy of 98.28%. However, VGG16 outperformed all other models in COVID-19 detection with an accuracy, F1 score, precision, specificity, and sensitivity of 98.72%, 97.59%, 96.43%, 98.70%, and 98.78%, respectively. The outstanding performance of these pretrained models can significantly improve the speed and accuracy of COVID-19 diagnosis. However, a larger dataset of COVID-19 X-ray images is required for a more accurate and reliable identification of COVID-19 infections when using deep transfer learning. This would be extremely beneficial in this pandemic when the disease burden and the need for preventive measures are in conflict with the currently available resources.


Author(s):  
Sanhita Basu ◽  
Sushmita Mitra ◽  
Nilanjan Saha

AbstractWith the ever increasing demand for screening millions of prospective “novel coronavirus” or COVID-19 cases, and due to the emergence of high false negatives in the commonly used PCR tests, the necessity for probing an alternative simple screening mechanism of COVID-19 using radiological images (like chest X-Rays) assumes importance. In this scenario, machine learning (ML) and deep learning (DL) offer fast, automated, effective strategies to detect abnormalities and extract key features of the altered lung parenchyma, which may be related to specific signatures of the COVID-19 virus. However, the available COVID-19 datasets are inadequate to train deep neural networks. Therefore, we propose a new concept called domain extension transfer learning (DETL). We employ DETL, with pre-trained deep convolutional neural network, on a related large chest X-Ray dataset that is tuned for classifying between four classes viz. normal, other_disease, pneumonia and Covid — 19. A 5-fold cross validation is performed to estimate the feasibility of using chest X-Rays to diagnose COVID-19. The initial results show promise, with the possibility of replication on bigger and more diverse data sets. The overall accuracy was measured as 95.3% ± 0.02. In order to get an idea about the COVID-19 detection transparency, we employed the concept of Gradient Class Activation Map (Grad-CAM) for detecting the regions where the model paid more attention during the classification. This was found to strongly correlate with clinical findings, as validated by experts.


Diagnostics ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 417 ◽  
Author(s):  
Mohammad Farukh Hashmi ◽  
Satyarth Katiyar ◽  
Avinash G Keskar ◽  
Neeraj Dhanraj Bokde ◽  
Zong Woo Geem

Pneumonia causes the death of around 700,000 children every year and affects 7% of the global population. Chest X-rays are primarily used for the diagnosis of this disease. However, even for a trained radiologist, it is a challenging task to examine chest X-rays. There is a need to improve the diagnosis accuracy. In this work, an efficient model for the detection of pneumonia trained on digital chest X-ray images is proposed, which could aid the radiologists in their decision making process. A novel approach based on a weighted classifier is introduced, which combines the weighted predictions from the state-of-the-art deep learning models such as ResNet18, Xception, InceptionV3, DenseNet121, and MobileNetV3 in an optimal way. This approach is a supervised learning approach in which the network predicts the result based on the quality of the dataset used. Transfer learning is used to fine-tune the deep learning models to obtain higher training and validation accuracy. Partial data augmentation techniques are employed to increase the training dataset in a balanced way. The proposed weighted classifier is able to outperform all the individual models. Finally, the model is evaluated, not only in terms of test accuracy, but also in the AUC score. The final proposed weighted classifier model is able to achieve a test accuracy of 98.43% and an AUC score of 99.76 on the unseen data from the Guangzhou Women and Children’s Medical Center pneumonia dataset. Hence, the proposed model can be used for a quick diagnosis of pneumonia and can aid the radiologists in the diagnosis process.


Sensors ◽  
2021 ◽  
Vol 21 (19) ◽  
pp. 6655
Author(s):  
Michael Horry ◽  
Subrata Chakraborty ◽  
Biswajeet Pradhan ◽  
Manoranjan Paul ◽  
Douglas Gomes ◽  
...  

Lung cancer is the leading cause of cancer death and morbidity worldwide. Many studies have shown machine learning models to be effective in detecting lung nodules from chest X-ray images. However, these techniques have yet to be embraced by the medical community due to several practical, ethical, and regulatory constraints stemming from the “black-box” nature of deep learning models. Additionally, most lung nodules visible on chest X-rays are benign; therefore, the narrow task of computer vision-based lung nodule detection cannot be equated to automated lung cancer detection. Addressing both concerns, this study introduces a novel hybrid deep learning and decision tree-based computer vision model, which presents lung cancer malignancy predictions as interpretable decision trees. The deep learning component of this process is trained using a large publicly available dataset on pathological biomarkers associated with lung cancer. These models are then used to inference biomarker scores for chest X-ray images from two independent data sets, for which malignancy metadata is available. Next, multi-variate predictive models were mined by fitting shallow decision trees to the malignancy stratified datasets and interrogating a range of metrics to determine the best model. The best decision tree model achieved sensitivity and specificity of 86.7% and 80.0%, respectively, with a positive predictive value of 92.9%. Decision trees mined using this method may be considered as a starting point for refinement into clinically useful multi-variate lung cancer malignancy models for implementation as a workflow augmentation tool to improve the efficiency of human radiologists.


Author(s):  
Ishtiaque Ahmed ◽  
◽  
Manan Darda ◽  
Neha Tikyani ◽  
Rachit Agrawal ◽  
...  

The COVID-19 pandemic has caused large-scale outbreaks in more than 150 countries worldwide, causing massive damage to the livelihood of many people. The capacity to identify contaminated patients early and get unique treatment is quite possibly the primary stride in the battle against COVID-19. One of the quickest ways to diagnose patients is to use radiography and radiology images to detect the disease. Early studies have shown that chest X-rays of patients infected with COVID-19 have unique abnormalities. To identify COVID-19 patients from chest X-ray images, we used various deep learning models based on previous studies. We first compiled a data set of 2,815 chest radiographs from public sources. The model produces reliable and stable results with an accuracy of 91.6%, a Positive Predictive Value of 80%, a Negative Predictive Value of 100%, specificity of 87.50%, and Sensitivity of 100%. It is observed that the CNN-based architecture can diagnose COVID19 disease. The parameters’ outcomes can be further improved by increasing the dataset size and by developing the CNN-based architecture for training the model.


2020 ◽  
Vol 28 (5) ◽  
pp. 841-850
Author(s):  
Saleh Albahli ◽  
Waleed Albattah

OBJECTIVE: This study aims to employ the advantages of computer vision and medical image analysis to develop an automated model that has the clinical potential for early detection of novel coronavirus (COVID-19) infected disease. METHOD: This study applied transfer learning method to develop deep learning models for detecting COVID-19 disease. Three existing state-of-the-art deep learning models namely, Inception ResNetV2, InceptionNetV3 and NASNetLarge, were selected and fine-tuned to automatically detect and diagnose COVID-19 disease using chest X-ray images. A dataset involving 850 images with the confirmed COVID-19 disease, 500 images of community-acquired (non-COVID-19) pneumonia cases and 915 normal chest X-ray images was used in this study. RESULTS: Among the three models, InceptionNetV3 yielded the best performance with accuracy levels of 98.63% and 99.02% with and without using data augmentation in model training, respectively. All the performed networks tend to overfitting (with high training accuracy) when data augmentation is not used, this is due to the limited amount of image data used for training and validation. CONCLUSION: This study demonstrated that a deep transfer learning is feasible to detect COVID-19 disease automatically from chest X-ray by training the learning model with chest X-ray images mixed with COVID-19 patients, other pneumonia affected patients and people with healthy lungs, which may help doctors more effectively make their clinical decisions. The study also gives an insight to how transfer learning was used to automatically detect the COVID-19 disease. In future studies, as the amount of available dataset increases, different convolution neutral network models could be designed to achieve the goal more efficiently.


Author(s):  
Ishtiaque Ahmed ◽  
◽  
Manan Darda ◽  
Neha Tikyani ◽  
Rachit Agrawal ◽  
...  

The COVID-19 pandemic has caused large-scale outbreaks in more than 150 countries worldwide, causing massive damage to the livelihood of many people. The capacity to identify contaminated patients early and get unique treatment is quite possibly the primary stride in the battle against COVID-19. One of the quickest ways to diagnose patients is to use radiography and radiology images to detect the disease. Early studies have shown that chest X-rays of patients infected with COVID-19 have unique abnormalities. To identify COVID-19 patients from chest X-ray images, we used various deep learning models based on previous studies. We first compiled a data set of 2,815 chest radiographs from public sources. The model produces reliable and stable results with an accuracy of 91.6%, a Positive Predictive Value of 80%, a Negative Predictive Value of 100%, specificity of 87.50%, and Sensitivity of 100%. It is observed that the CNN-based architecture can diagnose COVID-19 disease. The parameters’ outcomes can be further improved by increasing the dataset size and by developing the CNN-based architecture for training the model.


2021 ◽  
Author(s):  
Japman Singh Monga ◽  
Yuvraj Singh Champawat ◽  
Seema Kharb

Abstract In the year 2020 world came to a halt due to spread of Covid-19 or SARS-CoV2 which was first identified in Wuhan, China. Since then, it has caused plethora of problems around the globe such as loss of millions of lives, economic instability etc. Less effectiveness of detection through Reverse Transcription Polymerase Chain Reaction and also prolonged time needed for detection through the same calls for a substitute for Covid-19 detection. Hence, in this study, we aim to develop a transfer learning based multi-class classifier using Chest X-Ray images which will classify the X-Ray images in 3 classes (Covid-19, Pneumonia, Normal). Further, the proposed model has been trained with deep learning classifiers namely: DenseNet201, Xception, ResNet50V2, VGG16, VGG-19, InceptionResNetV2 .These are evaluated on the basis of accuracy, precision and recall as performance parameters. It has been observed that DenseNet201 is the best deep learning model with 82.2% accuracy.


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