scholarly journals The unintended benefit of the risk factor mandate of 2005

Author(s):  
Allen H. Huang ◽  
Jianghua Shen ◽  
Amy Y. Zang

AbstractIn 2005, the SEC mandated that firms disclose risk factors to provide useful information about firm risk. An unintended effect of the mandate is that mandatory risk factor (RF) disclosure may constitute “meaningful cautionary language” as defined in the Private Securities Litigation Reform Act, and may therefore provide legal protection for forward-looking statements (FLSs). Using both a difference-in-differences design and a two-stage least squares approach, we find that, following the mandate, firms that had not previously disclosed risk factors (late RF disclosers) became more willing to provide qualitative FLSs, particularly positive ones, than other firms. This finding is consistent with our prediction that, for late RF disclosers, the mandate reduces managers’ perceived litigation risk. We also find that these firms experience improvement in their information environment. A path analysis reveals that the mandate improves firms’ information environment not only directly but also indirectly by prompting more disclosure of positive FLSs, illustrating an unintended benefit of the 2005 RF mandate. Cross-sectional tests show that the RF mandate induces a larger increase in positive FLSs for firms whose managers perceive a higher level of benefit from safe harbor protection arising from meaningful cautionary statements.

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 418
Author(s):  
Maria Maroudia Berikopoulou ◽  
Aikaterini Pana ◽  
Theodota Liakopoulou-Tsitsipi ◽  
Nikos F. Vlahos ◽  
Vasiliki Papaevangelou ◽  
...  

Group B streptococcus (GBS) is a leading cause of serious neonatal infections. Maternal GBS colonization is associated with early- and late-onset neonatal disease (EOD/LOD). In Greece, a screening-based strategy is recommended, in which concurrent vaginal-rectal cultures should be obtained between 36 0/7 and 37 6/7 weeks’ gestation. We sought to examine the level of adherence to the GBS screening guidelines and estimate the prevalence of GBS colonization among pregnant women. Although in Greece the screening-based strategy is followed, we also examined known EOD risk factors and linked them to GBS colonization. A cross-sectional study of 604 women postpartum in three hospitals and maternity clinics was conducted. Following written informed consent, data were collected via a short self-completed questionnaire and review of patients’ records. In 34.6% of the enrolled pregnant women, no culture had been taken. Of the remaining, 12.8% had proper vaginal-rectal sample collections. The overall maternal colonization rate was 9.6%. At least one risk factor for EOD was identified in 12.6% of participants. The presence of risk factors was associated with positive cultures (p = 0.014). The rate of culture collection did not differ between women with or without an EOD risk factor. Adherence to a universal screening of pregnant women with vaginal-rectal cultures was poor. Despite probable underestimation of GBS carrier status, almost 1 in 10 participants were GBS positive during pregnancy. Screening of women with risk factors for EOD should, at least, be prioritized to achieve prevention and prompt intervention of EOD.


2016 ◽  
Vol 137 (2) ◽  
pp. 114-121 ◽  
Author(s):  
Yelena Bird ◽  
Mark Lemstra ◽  
Marla Rogers

Background: Stroke is a major chronic disease and a common cause of adult disability and mortality. Although there are many known risk factors for stroke, lower income is not one that is often discussed. Aims: To determine the unadjusted and adjusted association of income distribution on the prevalence of stroke in Saskatchewan, Canada. Methods: Information was collected from the Canadian Community Health Survey conducted by Statistics Canada for 2000–2008. In total, 178 variables were analysed for their association with stroke. Results: Prior to statistical adjustment, stroke was seven times more common for lower income residents than higher income residents. After statistical adjustment, only four covariates were independently associated with stroke prevalence, including having high blood pressure (odds ratio (OR) = 2.62; 95% confidence interval (CI) = 2.12–3.24), having a household income below CAD$30,000 per year (OR = 2.49; 95% CI = 1.88–3.29), being a daily smoker (OR = 1.36; 95% CI = 1.16–1.58) and being physically inactive (OR = 1.27; 95% CI = 1.13–1.43). After statistical adjustment, there were five covariates independently associated with high blood pressure prevalence, including having a household income below CAD$30,000 per year (OR = 1.52; 95% CI = 1.41–1.63). After statistical adjustment, there were five covariates independently associated with daily smoking prevalence, including having a household income below CAD$30,000 per year (OR = 1.29; 95% CI = 1.25–1.33). Conclusions: Knowledge of disparities in the prevalence, severity, disability and mortality of stroke is critically important to medical and public health professionals. Our study found that income distribution was strongly associated with stroke, its main disease intermediary – high blood pressure – and its main risk factor – smoking. As such, income is an important variable worthy of public debate as a modifiable risk factor for stroke.


2021 ◽  
Vol 5 (9) ◽  
pp. 871-878
Author(s):  
M. Farhan Fadhillah ◽  
Chairil Anwar ◽  
Iche Andriyani Liberty

Introduction. Pediculosis capitis is a disease of the scalp caused by infestation of Pediculus humanus capitis with symptoms such as itching and sensation of movement in the hair. The purpose of this study was to determine the risk factors and incidence of pediculosis capitis in the Baturaja orphanage.Methods. This research is an analytic observational study using a cross-sectional design with field and laboratory research. The population of this study were all children in the Baturaja orphanage who met the inclusion and exclusion criteria, as many as 172 children. All children present were taken as subjects. Data obtained by questionnaires, interviews and direct observation of the sample.Results. The results of this study showed the prevalence of pediculosis capitis in the Baturaja orphanage was 19.1%. In this study, it was found that there was a significant relationship between age (p = 0.000), education (p = 0.000), the use of shared pillows (p = 0.000), the use of shared combs (p = 0.000), the use of shared towels (p = 0.000), knowledge (p = 0.000), attitudes and behavior (p = 0.000) with the incidence of pediculosis capitis. Multivariate analysis showed that the most dominant risk factor for the incidence of pediculosis capitis in the Baturaja orphanage was age (p=0.036), while behavior was a protective factor for the incidence of pediculosis capitis.Conclusion. There is a significant relationship between age, education, use of shared pillows, use of shared combs, use of shared towels, knowledge, attitudes, behavior with the incidence of pediculosis capitis. The most dominant risk factor for the incidence of pediculosis capitis in the Baturaja orphanage is age, while behavior is a protective factor for the incidence of pediculosis capitis.


2009 ◽  
Vol 13 (4) ◽  
pp. 488-495 ◽  
Author(s):  
Ahmet Selçuk Can ◽  
Emine Akal Yıldız ◽  
Gülhan Samur ◽  
Neslişah Rakıcıoğlu ◽  
Gülden Pekcan ◽  
...  

AbstractObjectiveTo identify the optimal waist:height ratio (WHtR) cut-off point that discriminates cardiometabolic risk factors in Turkish adults.DesignCross-sectional study. Hypertension, dyslipidaemia, diabetes, metabolic syndrome score ≥2 (presence of two or more metabolic syndrome components except for waist circumference) and at least one risk factor (diabetes, hypertension or dyslipidaemia) were categorical outcome variables. Receiver-operating characteristic (ROC) curves were prepared by plotting 1 − specificity on the x-axis and sensitivity on the y-axis. The WHtR value that had the highest Youden index was selected as the optimal cut-off point for each cardiometabolic risk factor (Youden index = sensitivity + specificity − 1).SettingTurkey, 2003.SubjectsAdults (1121 women and 571 men) aged 18 years and over were examined.ResultsAnalysis of ROC coordinate tables showed that the optimal cut-off value ranged between 0·55 and 0·60 and was almost equal between men and women. The sensitivities of the identified cut-offs were between 0·63 and 0·81, the specificities were between 0·42 and 0·71 and the accuracies were between 0·65 and 0·73, for men and women. The cut-off point of 0·59 was the most frequently identified value for discrimination of the studied cardiometabolic risk factors. Subjects classified as having WHtR ≥ 0·59 had significantly higher age and sociodemographic multivariable-adjusted odds ratios for cardiometabolic risk factors than subjects with WHtR < 0·59, except for diabetes in men.ConclusionsWe show that the optimal WHtR cut-off point to discriminate cardiometabolic risk factors is 0·59 in Turkish adults.


Neurology ◽  
2018 ◽  
Vol 91 (16) ◽  
pp. e1479-e1486 ◽  
Author(s):  
Matthew P. Pase ◽  
Kendra Davis-Plourde ◽  
Jayandra J. Himali ◽  
Claudia L. Satizabal ◽  
Hugo Aparicio ◽  
...  

ObjectiveGiven the potential therapeutic effect of vascular disease control timing to reduce dementia risk, we investigated the age-related influences of vascular risk factor burden on brain structure throughout the lifespan.MethodsWe studied participants from the community-based prospective Framingham Heart Study. Overall vascular risk factor burden was calculated according to the Framingham Stroke Risk Profile, a validated algorithm that predicts stroke risk. Brain volume was estimated by MRI. We used cross-sectional data to examine how the strength of association between vascular risk factor burden and brain volume changed across each age decade from age 45–54 years through to 85–94 years (N = 2,887). Second, we leveraged up to 40 years of longitudinal data to determine how the strength of association between vascular risk factor burden and brain volume changed when vascular risk factors were examined at progressively earlier ages (N = 7,868).ResultsIn both cross-sectional and longitudinal analyses, higher vascular risk factor burden was associated with lower brain volume across each age decade. In the cross-sectional analysis, the strength of this association decreased with each decade of advancing age (p for trend < 0.0001). In longitudinal analysis, the strength of association between vascular risk factor burden and brain volume was stronger when vascular risk factors were measured at younger ages. For example, vascular risk factor burden was most strongly associated with lower brain volume in later life when vascular risk factors were measured at age 45 years.ConclusionVascular risk factors at younger ages appear to have detrimental effects on current and future brain volume.


2016 ◽  
Vol 50 (1) ◽  
pp. 31
Author(s):  
Nila Kusumasari ◽  
Rinawati Rohsiswatmo ◽  
Djajadiman Gatot ◽  
Darlan Darwis

Background Thrombocytopenia is the most common hematological abnormality in the neonatal period. Hemorrhagic manifestations are found in 10% cases of thrombocytopenia. Neonatal thrombocytopenia commonly assumed due to sepsis, despite many risk factors that may caused thrombocytopenia.Objective To obtain incidence and risk factors of neonatal thrombocytopenia.Methods A cross sectional study was conducted in April 2009. Complete blood counts investigation was performed before age of 24 hours, medical conditions and risk factors of mothers and subjects were noted, as well as hemorrhagic manifestations. Subjects with thrombocytopenia were followed for 2 weeks. The risk factors consisted of hypertension in pregnancy, pre-eclampsia, eclampsia, intrauterine growth retardation, gestational diabetes mellitus, perinatal infection, asphyxia, sepsis, and necrotizing enterocolitis.Results Neonatal thrombocytopenia was found 17 (12.1%) of 140 subjects, consisted of 88.2% early onset and 11.8% late onset. Significant risk factor of mother was pre-eclampsia (PR 3.97, 95%CI 1.70 to 9.25), while significant risk factors of neonates were asphyxia (PR 5.66, 95%CI 2.49 to 12.86), sepsis (PR 5.33, 95%CI 2.33-12.19) and necrotizing enterocolitis (p=0.014; PR 9.2 95% CI 5.17 to14.84). We found 29.4% hemorrhagic cases of neonatal thrombocytopenia (i.e.,. skin, gastrointestinal, intracranial hemorrhage).Conclusions The incidence of neonatal thrombocytopenia was 12.2%. Significant risk factor of mother that caused thrombocytopenia was pre-eclampsia, while risk factors of neonates were asphyxia, sepsis and necrotizing enterocolitis.[Paediatr Indones. 2010;50:31-7].


Cholesterol ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-7
Author(s):  
Vincenzo Capuano ◽  
Norman Lamaida ◽  
Ernesto Capuano ◽  
Rocco Capuano ◽  
Eduardo Capuano ◽  
...  

The aim of this study was to determine the trends of cardiovascular risk factor prevalence between 1988/9 and 2008/9 in the 25–74-year-old population in an area of Southern Italy. We compared three cross-sectional studies conducted in random population samples, in 1988/9, 1998/9, and 2008/9 in Salerno, Italy. The methodology of data collection (lipid profile, systolic and diastolic blood pressure, glycaemia, and smoking) and conducting tests which the population underwent during the three phases was standardized and comparable. Prevalence of diabetes, hypertension, hypercholesterolemia, and smoking was calculated and standardized for age. A total of 3491 subjects were included. From 1988/9 to 2008/9, in males, the prevalence of all four risk factors was reduced. In women, there was a clear reduction of hypertension, a similar prevalence of hypercholesterolemia, and an increase of smoking and diabetes. In the area of Salerno, our data confirm that the global prevalence of the major risk factors is decreasing in men, but their absolute values are still far from optimization. In women, diabetes and smoking showed a negative trend, therefore requiring targeted interventions. These data are now used as a base for executive targeted programs to improve prevention of cardiovascular disease in our community.


2021 ◽  
Vol 12 (1) ◽  
pp. 69-76
Author(s):  
Rico Januar Sitorus ◽  
Nyoman Yudi Antara ◽  
Rosyada Elviani ◽  
Zen Ahmad ◽  
Harun Hudari ◽  
...  

World Health Organization (WHO) has declared the novel corona virus (COVID-19) as a pandemic due to its high transmission and the rapid spread of the COVID-19. Along these lines, there is a need for more research about risk factors that can affect the spread of COVID-19 and its fatality. Therefore, this study aims to analyze risk factors in patients who died from COVID-19 at the Mohammad Hoesin Hospital in Palembang, South Sumatra, Indonesia. This study used a cross-sectional approach. The data were collected from all patients who died with suspected, probable, and confirmed status until September 2020  Data on death due to COVID-19 were collected with suspect, probable, and confirmed status. The results showed that comorbidity became the most dominant factor (62.1%) with (OR Adj) 3.780 (1.000 – 3.168) after controlling for contact history with confirmed cases and sex. There were differences in the mean age and length of stay in patients with confirmed COVID-19 and not. Prevention of death in COVID-19 patients can be done by controlling comorbidities and contact history with positive cases of COVID-19.


2017 ◽  
Vol 2 (1) ◽  
pp. 43
Author(s):  
Sofia Sofia

Acute Respiratory Infection (ARI) is still one public health problem that is important to note, because it is an acute illness and can even cause death in infants in developing countries, including Indonesia. In general, there are three the risk factors of ARI namely environmental factors, individual factors of children, and behavioral factors. The aim of research to find out the environmental risk factors with the incidence of  ARI  in Toddlers in Public Health Center of Ingin Jaya, Aceh Besar district. This type of research is an analytic survey with cross-sectional study approach. The sample size is calculated using the formula Lemeshow of 100 respondents, samples were taken randomly. Data analysis using Chi-Square test. The results showed that the level of humidity in the home (p= 0,039), smoking habits of family members in the home (p= 0,001), and the habit of using mosquito coils in the home (p= 0,003) as a risk factor for ISPA to children in Region Public Health Center of Ingin Jaya, Aceh Besar district. Conclusion, risk factor of ARI in the toddler that is a smoking habit, usage habit of mosquito coil and air humidity. Suggestions, the public in order to maintain air quality in the home environment to avoid various transmission of infectious diseases.Keywords: Air humidity, habits, environment, ARIPenyakit Infeksi Saluran Pernafasan Akut (ISPA) masih menjadi salah satu masalah kesehatan masyarakat yang penting untuk diperhatikan, karena merupakan penyakit akut dan bahkan dapat menyebabkan kematian pada balita di berbagai negara berkembang termasuk  Indonesia. Secara umum ada 3 (tiga) faktor risiko terjadinya ISPA yaitu faktor lingkungan, faktor individu anak, serta faktor perilaku. Tujuan penelitian untuk mengetahui faktor risiko lingkungan dengan kejadian ISPA pada Balita di wilayah kerja Puskesmas Ingin Jaya Kabupaten Aceh Besar. Jenis penelitian adalah survey analitik dengan pendekatan Crossectional study. Besarnya sampel dihitung dengan menggunakan rumus lameshow yaitu 100 responden, sampel diambil secara acak sederhana. Analisa data dengan menggunakan uji Chi-Square. Hasil penelitian menunjukkan bahwa tingkat kelembaban udara dalam rumah (p=0,039), kebiasaan merokok anggota keluarga dalam rumah (p=0,001), dan kebiasaan menggunakan obat nyamuk bakar di dalam rumah (p=0,003) sebagai faktor risiko kejadian ISPA pada Balita di wilayah kerja Puskesmas Ingin Jaya Kabupaten Aceh Besar. Kesimpulan, faktor risiko ISPA pada balita yaitu kebiasaan merokok, kebiasaan penggunaan obat nyamuk bakar dan kelembaban udara. Saran, masyarakat agar dapat menjaga kualitas udara dilingkungan rumah agar terhindar dari berbagai penularan penyakit infeksi. Kata kunci: Kelembaban udara, kebiasaan, lingkungan, ISPA


2021 ◽  
Vol 5 (3) ◽  
pp. 843-850
Author(s):  
M. Farhan Fadhillah ◽  
Chairil Anwar ◽  
Iche Andriyani Liberty

Introduction. Pediculosis capitis is a disease of the scalp caused by infestation of Pediculus humanus capitis with symptoms such as itching and sensation of movement in the hair. The purpose of this study was to determine the risk factors and incidence of pediculosis capitis in the Baturaja orphanage.Methods. This research is an analytic observational study using a cross-sectional design with field and laboratory research. The population of this study were all children in the Baturaja orphanage who met the inclusion and exclusion criteria, as many as 172 children. All children present were taken as subjects. Data obtained by questionnaires, interviews and direct observation of the sample.Results. The results of this study showed the prevalence of pediculosis capitis in the Baturaja orphanage was 19.1%. In this study, it was found that there was a significant relationship between age (p = 0.000), education (p = 0.000), the use of shared pillows (p = 0.000), the use of shared combs (p = 0.000), the use of shared towels (p = 0.000), knowledge (p = 0.000), attitudes and behavior (p = 0.000) with the incidence of pediculosis capitis. Multivariate analysis showed that the most dominant risk factor for the incidence of pediculosis capitis in the Baturaja orphanage was age (p=0.036), while behavior was a protective factor for the incidence of pediculosis capitis.Conclusion. There is a significant relationship between age, education, use of shared pillows, use of shared combs, use of shared towels, knowledge, attitudes, behavior with the incidence of pediculosis capitis. The most dominant risk factor for the incidence of pediculosis capitis in the Baturaja orphanage is age, while behavior is a protective factor for the incidence of pediculosis capitis.


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