Longitudinal investigation of cognitive deficits in breast cancer patients and their gray matter correlates: impact of education level

2018 ◽  
Vol 14 (1) ◽  
pp. 226-241 ◽  
Author(s):  
Joy Perrier ◽  
Armelle Viard ◽  
Christelle Levy ◽  
Nastassja Morel ◽  
Djelila Allouache ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Gray Matter ◽  
Cognitive Deficits ◽  
Education Level ◽  
Breast Cancer Patients ◽  
Longitudinal Investigation

scholarly journals Lifestyle breast cancer patients among Indonesian women: A nationwide survey

2021 ◽  
Vol 10 (4) ◽  
pp. 730
Author(s):  
Solikhah Solikhah ◽  
Khairunnisaa Nuur Aliifah Setyawati ◽  
Monthida Sangruangake
Keyword(s):  
Breast Cancer ◽  
High School ◽  
Cancer Patients ◽  
Breast Cancer Incidence ◽  
Education Level ◽  
Lifestyle Changes ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Significance Level

Recently, cancer is a major health problem in the world. Lifestyle changes and growing urbanization likely led to increasing breast cancer incidence in such in Indonesia. Therefore, this study aimed to explore lifestyle breast cancer patients among Indonesian women. The investigation was a cross-sectional study distributed among 3,392 females drawn from 13 out of 27 provinces in Indonesia. Multiple binary logistic regressions were conducted to investigate breast cancer risk among Indonesian. A significance level of 0.05 was employed in all analysis. Of the 3,392 respondents included in the analysis, more than half (52.71%; n=1,788) was aged 40–49 years old. The most common marital status of the participants was married (98.20%; n=3,331), followed by no smoking (94.69%; n=3,212) and active exercise (62.12%; n=2,107). Education level was significantly associated with breast cancer (AdjOR_Junior high school=0.21; 95%CI=0.06 to 0.70; p<0.01 and AdjOR_senior high school=0.60; 95%CI=0.15 to 2.26; p<0.05). Education level was significantly related to breast cancer. Lifestyle such as smoking and physical activity was suspected to affect breast cancer indirectly.

Persistent cognitive deficits in breast cancer survivors treated with adjuvant chemotherapy: Neuropsychological and neurophysiological evidence

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 8556-8556
Author(s):  
S. B. Schagen ◽  
B. Kreukels ◽  
F. Van Dam
Keyword(s):  
Breast Cancer ◽  
Information Processing ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Neuropsychological Assessment ◽  
Cognitive Deficits ◽  
Healthy Controls ◽  
Breast Cancer Patients ◽  
Neurophysiological Assessment ◽  
One Year

8556 Background: Cognitive deficits are reported in several studies in women with breast cancer treated with adjuvant chemotherapy. The current aim was to investigate whether breast cancer patients that had deviant cognitive performance on neuropsychological tests one year after treatment, differed from patients with intact performance on neurophysiological parameters and self-reported complaints, this time examined five years post treatment. Methods: 63 breast cancer patients treated with CMF chemotherapy underwent neuropsychological testing one year post therapy. Their performance was compared to that of healthy controls (n=60). 26 of these patients were examined neurophysiologically 4 years after the initial neuropsychological assessment. Neurophysiological assessment included quantitative EEG, auditory oddball task and a visual information processing task with concurrent EEG registration. Patients were also interviewed regarding cognitive complaints experienced in daily life. Results: At the initial neuropsychological assessment 33.3% of breast cancer patients treated with CMF chemotherapy were classified as cognitively impaired compared to 10% of healthy controls (p=.01). At the neurophysiological assessment four years later, patients that scored in the impaired range on the initial neuropsychological examination had significantly longer P3 latencies and reduced P3 amplitudes in an information processing task. The impaired patients also made more errors, had longer reaction times, and reported more cognitive complaints. Conclusion: The results of this study show converging neuropsychological and neurophysiological evidence for the persistence of cognitive problems in breast cancer patients up to five years after completion of CMF chemotherapy. [Table: see text] No significant financial relationships to disclose.

Involvement levels of breast cancer patients—Seeking trusted hospital and physician

2021 ◽  
pp. 135910532110623
Author(s):  
Hovav Boaz ◽  
Brammli-Greenberg Shuli
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Cancer Patients ◽  
Surgical Procedure ◽  
Breast Cancer Survivors ◽  
Treatment Decisions ◽  
Education Level ◽  
Location Decisions ◽  
Breast Cancer Patients ◽  
Active Involvement

The active involvement levels of breast cancer patients (BCP) in treatment decisions range from 10% to 81%. We investigated the involvement levels of 179 Israeli breast cancer survivors, aged 30 to 81, in the choice of hospital, surgeon, surgical procedure, chemotherapy, and radiotherapy. High involvement was documented in location decisions (operating hospital 77%, chemotherapy facility 82%) as opposed to low involvement in treatment decisions (chemotherapy 30%–38%, radiotherapy 25%, surgical procedure 31%). Involvement was influenced by hospital and surgeon reputation, education level, and income. BCPs actively choose their treating facility and staff, and then follow their doctor’s recommendations.

scholarly journals Factors Associated with The Resilience of Breast Cancer Patients Undergoing Chemotherapy

2020 ◽  
Vol 6 (2) ◽  
pp. 89
Author(s):  
Ariyani Wisudawati Nira ◽  
Mira Triharini ◽  
Aria Aulia Nastiti
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Family Support ◽  
Cancer Patients ◽  
Economic Status ◽  
Nursing Intervention ◽  
Education Level ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Factors Associated

Introduction: The management of chemotherapy in breast cancer requires a long time and cause miscellaneous of side effects. High resilience is needed by breast cancer patients to undergo chemotherapy regularly. This study aimed to analyze factors associated with the resilience of breast cancer patients undergoing chemotherapy.Methods: This study design was cross-sectional. From the total population of 122 breast cancer patients, a sample of 100 participants was selected using a purposive sampling technique. The independent variables were hardiness, education level, economic status, side effects of chemotherapy, family support, and anxiety. The dependent variable was resilience. The instruments of this study were Hardiness questionnaire, Chemothraphy-Symptom Assessment Scale (C-SAS), Family Support questionnaire, Zung-Self Rating Anxiety Scale (ZSRAS), and Connor-Davidson Resilience Scale (CD-RISC). The Spearmen’s Rho was used for statistical analysis.Results: Hardiness (p=0.000; r=0.310), Education Level (p=0.000; r=0.416), Economic Status (p=0.000; r=0.369), Side Effects of Chemotherapy (p=0.004; r=-0.283) and Family Support (p=0.000; r=0.579) have relation with the resilience. Anxiety has no relation with the resilience (p=0.23; r=0.121).Conclusion: The side effects management of chemotherapy and family support were necessary to increase the resilience of breast cancer patients undergoing chemotherapy. It is highly recommended to the next researchers to do some studies about factors associated with the side effects of chemotherapy and nursing intervention, which can reduce the side effects of chemotherapy itself.

scholarly journals Benefit Discovery Level and Influencing Factors of Postoperative Breast Cancer Patients

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Qin Dai ◽  
Lanfeng Zhang ◽  
Lili Zhu ◽  
Chunxiu He
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Influencing Factors ◽  
Stepwise Regression ◽  
Sampling Method ◽  
Rating Scale ◽  
General Information ◽  
Education Level ◽  
Breast Cancer Patients

Objective: To investigate the level and influencing factors of benefit discovery in patients with breast cancer after operation. Methods: Convenient sampling method was used to evaluate the change of benefit discovery level of 60 patients with breast cancer after operation in a cancer ward of a hospital by using Chinese version of benefit discovery rating scale and general information questionnaire. Results: The level of benefit discovery of breast cancer patients at different stages was statistically different (P < 0.05). Age and education level entered the multiple linear stepwise regression equation of influencing factors of benefit discovery level of breast cancer patients (P < 0.05). Conclusion: Targeted nursing measures should be taken to improve the quality of life of patients with breast cancer.

Drug- and patient-related factors are the strongest predictors of endocrine therapy adherence in breast cancer patients

2021 ◽  
pp. 107815522110208
Author(s):  
Mariam F Haji-Hersi ◽  
Sophia Tilley ◽  
Caleb A Shelton ◽  
Nathan Lamb ◽  
Landry K Kamdem
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Cancer Patients ◽  
Endocrine Therapy ◽  
Breast Cancer Treatment ◽  
Education Level ◽  
Breast Cancer Patients ◽  
Personal Beliefs ◽  
Related Factors ◽  
Treatment Plans

Purpose Medication non-adherence to treatment regimens can severely impact the mortality of patients afflicted with breast cancer.The purpose of this study was to identify factors that contribute to non-adherence to endocrine therapy in breast cancer treatment plans. Methods Thirty-two women with a breast cancer diagnosis were surveyed by pharmacists and pharmacy students to identify the patient- related factors (e.g. patient personal beliefs, education level), drug-related factors (e.g. patient drug allergies), socio-economic factors (e.g. patient ability to pay for the medication) and healthcare system factors (e.g. poor patient-healthcare provider relationship) that may impact non-adherence to endocrine therapy in breast cancer treatment plans. Medication adherence rates were measured using the Medication Adherence Rating Scale (MARS-8) system. Associations between adherence rate scores and clinical variables (e.g. age, tobacco use, alcohol consumption, cost of treatment, education level, personal beliefs, drug allergies, patient/provider relationship, adverse events) were carried out using Spearman Correlation, T-Test, Mann-Whitney U Test, and X2 tests. A p value of ≤ 0.05 was considered statistically significant. Results Our study found that 59% of survey respondents were non-adherent to their endocrine therapy in breast cancer treatment plans. Drug allergies ( p = 0.000069), patient ability to pay ( p = 0.005), poor personal beliefs about the prescribed therapy (p = 0.009), low education level ( p = 0.025), adverse drug events ( p = 0.026), and poor patient-provider relationship ( p = 0.05) were found to play a role in patient non-adherence to treatment. Conclusions Our study found that drug- (e.g. allergies), socio-economic (e.g. patient ability to pay), and patient-related factors (e.g. personal beliefs) are the strongest predictors of adherence among breast cancer patients undergoing endocrine therapy. These findings support the need for a better relationship between breast cancer patients and their healthcare providers, including drug experts such as pharmacists.

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