scholarly journals Clinical characteristics and risk factors for mortality in cancer patients with COVID-19

2021 ◽  
Author(s):  
Junnan Liang ◽  
Guannan Jin ◽  
Tongtong Liu ◽  
Jingyuan Wen ◽  
Ganxun Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Clinical Characteristics

scholarly journals Predictive factors of posttreatment fracture by definitive radiotherapy for uterine cervical cancer

2020 ◽  
Author(s):  
Kazuki Ishikawa ◽  
Tsuneo Yamashiro ◽  
Takuro Ariga ◽  
Takafumi Toita ◽  
Wataru Kudaka ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cervical Cancer ◽  
Multivariate Analysis ◽  
Radiation Therapy ◽  
Cancer Patients ◽  
Clinical Characteristics ◽  
Univariate Analysis ◽  
Uterine Cervical Cancer

Abstract Purpose Fractures are known to shorten life expectancy and worsen the quality of life. The risk of fractures after radiation therapy in cervical cancer patients is known to be multifactorial. In this study, we examined risk factors for fractures in cervical cancer patients, especially by evaluating bone densities and DVH parameters for fractured bones. Materials and Methods For 42 patients, clinical characteristics, pretreatment CT bone densities, and radiation dose were compared between patients with and without fractures. Results Posttreatment fractures occurred in 25 bones among ten patients. Pretreatment CT bone densities were significantly lower in patients with fractures (P < 0.05–0.01 across sites, except for the ilium and the ischium). Although DVH parameters were also significantly associated with fractures in univariate analysis, only CT densities were significantly associated with fractures in multivariate analysis. Conclusion Pretreatment CT densities of spinal and pelvic bones, which may reflect osteoporosis, have a significant impact on the risk for posttreatment fractures.

scholarly journals Clinical Characteristics, Risk Factors and Cardiac Manifestations of Cancer Patients with COVID-19

2021 ◽  
Author(s):  
Yan Huang ◽  
Zhenhong Hu ◽  
Dong Hu ◽  
Zhou Quan ◽  
Xiaoyang Zhou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Clinical Characteristics ◽  
Cardiac Manifestations

scholarly journals Clinical Characteristics of COVID-19-Infected Cancer Patients in Pakistan: Differences Between Survivors and Non-Survivors

2021 ◽  
Vol 11 ◽  
Author(s):  
Kashif Asghar ◽  
Muhammad Abu Bakar ◽  
Muhammad Junaid Akram ◽  
Asim Farooq ◽  
Kashif Siddique ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Clinical Characteristics ◽  
Clinicopathological Characteristics ◽  
Research Centre ◽  
Common Symptom ◽  
Chi Square ◽  
Exact Test ◽  
Logistic Regression Models ◽  
D Dimer

BackgroundCancer patients are considered as highly vulnerable individuals in the current COVID-19 pandemic. We studied the clinical characteristics of survivor and non-survivor COVID-19-infected cancer patients in Pakistan.Patients and MethodsWe did a retrospective study of 70 cancer patients with PCR-confirmed COVID-19 infection from Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore and Peshawar, Pakistan between April 13 and July 09, 2020. These patients were discharged from the hospital or had died by July 09, 2020. Clinical, pathological and radiological characteristics were compared between survivors and non-survivors by fisher’s exact test and chi-square test. Univariable and multivariable logistic regression models were performed to explore the risk factors of mortality.ResultsSeventy cancer patients with SARS-CoV-2 infection were enrolled and the majority were males 38 (54.3%). 57 (81.4%) had solid tumors and 13 (18.6%) had hematological malignancies. Dyspnea (44 cases) was the most common symptom (62.9%). Complications were reported in 51 (72.9%) patients during the course of disease. 19 (27.1%) patients were admitted to an intensive care unit (ICU). A significant increase in the C-reactive protein level and neutrophil count was observed in the deceased patients as compared to the surviving patients. D-dimer values of ≥0.2 mg/L were significantly associated with mortality (P=0.01). We identified two independent risk factors associated with death, ICU admission (P=0.007) and D-dimer (P=0.003).ConclusionPakistani cancer patients with COVID-19 infection reported poor prognosis. Intensive surveillance of clinicopathological characteristics of cancer patients infected with COVID-19 especially D-dimer values may play a pivotal role in the outcome of the disease.

Blastocystis subtypes in cancer patients: Analysis of possible risk factors and clinical characteristics

2016 ◽  
Vol 65 (6) ◽  
pp. 792-796 ◽  
Author(s):  
Ozlem Yersal ◽  
Erdogan Malatyali ◽  
Hatice Ertabaklar ◽  
Esin Oktay ◽  
Sabri Barutca ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Clinical Characteristics

scholarly journals Checkpoint inhibitor pneumonitis in Chinese lung cancer patients: clinical characteristics and risk factors

2020 ◽  
Vol 9 (6) ◽  
pp. 3957-3965
Author(s):  
Chen Zhang ◽  
Fangyan Gao ◽  
Shidai Jin ◽  
Wen Gao ◽  
Shuangjing Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Clinical Characteristics ◽  
Checkpoint Inhibitor ◽  
Lung Cancer Patients

OC-0059 Clinical characteristics and risk factors for local failure in cervix cancer patients after MR IGABT

2021 ◽  
Vol 158 ◽  
pp. S45
Author(s):  
M. Schmid ◽  
U. Mahantshetty ◽  
C. Kirisits ◽  
K. Tanderup ◽  
C. Haie-Meder ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Clinical Characteristics ◽  
Cervix Cancer ◽  
Local Failure

214: Incidence and Risk Factors of Symptomatic DVT in Prostate Cancer Patients Undergoing Laparoscopic Radical Prostatectomy

2006 ◽  
Vol 175 (4S) ◽  
pp. 70-71
Author(s):  
Fernando P. Secin ◽  
Clément-Claude Abbou ◽  
Inderbir S. Gill ◽  
Georges Fournier ◽  
Thierry Piéchaud ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Risk Factors ◽  
Radical Prostatectomy ◽  
Cancer Patients ◽  
Laparoscopic Radical Prostatectomy

Incidence and Risk Factors of the Infusion-Related Reactions in Breast Cancer Patients Receiving Trastuzumab

2018 ◽  
Vol 35 (2) ◽  
pp. 177-183
Author(s):  
정지혜 ◽  
여미진 ◽  
박애령 ◽  
황보신이 ◽  
나현오 ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Patients ◽  
Breast Cancer Patients

KIDNEY INJURY IN CANCER THERAPY

2018 ◽  
Vol 22 (5) ◽  
pp. 17-24 ◽  
Author(s):  
E. V. Burnasheva ◽  
Y. V. Shatokhin ◽  
I. V. Snezhko ◽  
A. A. Matsuga
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Cancer Therapy ◽  
Cancer Patients ◽  
Cytotoxic Effect ◽  
Tumor Lysis Syndrome ◽  
Kidney Injury ◽  
Chemotherapeutic Agents ◽  
Oxygen Intermediates ◽  
Circulating Blood Volume

Кidney injury is a frequent and significant complication of cancer and cancer therapy. The kidneys are susceptible to injury from malignant infiltration, damage by metabolites of malignant cells, glomerular  injury, nephrotoxic drugs including chemotherapeutic agents. Also  bone marrow transplantation complications, infections with immune  suppression (including septicemia), tumor lysis syndrome should be  taken into account. Chemotherapeutic agents are a common cause  of acute kidney injury but can potentially lead to chronic kidney  disease development in cancer patients. This article summarizes risk  factors of acute kidney injury in cancer patients. Risk factors are  divided into two groups. The systemic are decrease of total  circulating blood volume, infiltration of kidney tissue by tumor cells,  dysproteinemia, electrolyte disturbances. The local (renal) risk  factors are microcirculation disturbances, drugs biotransformation  with formation of reactive oxygen intermediates, high concentration of nephrotoxic agents in proximal tubules and its  sensitivity to ischemia. Drug-related risk factors include: drugs  combination with cytotoxic effect high doses long term use necessity, direct cytotoxic effect of not only chemotherapeutic agents but also its metabolites, mean solubility forming intratubular  precipitates. Early diagnosis, timely prevention and treatment of  these complications provide significantly improve nononcologic results of treatment.

Sign in / Sign up

Export Citation Format

Share Document