Correction to: Dilution of QuEChERS Extracts Without Cleanup Improves Results in the UHPLC-MS/MS Multiresidue Analysis of Pesticides in Tomato

The paper would like to show a direct injection into GC-MS/QqQ for the determination of secondary aromas in white wine samples fermented in two different ways. The procedure has been compared with more traditional methods used in this field, i.e., headspace analysis and liquid–liquid extraction. The application of such direct injection, for the first time in the literature, allows us to analyze Volatile Organic Compounds (VOCs) in the range 0.1–100 µg mL−1, with Limits of Detection (LODs) and Limits of Quantification (LOQs) between 0.01–0.05 µg mL−1 and 0.03–0.09 µg mL−1, respectively, intraday and interday below 5.6% and 8.5%, respectively, and recoveries above 92% at two different fortification levels. The procedure has been applied to real wine samples: it evidences how the fermentation in wood (cherry) barrel yields higher VOC levels than ones in wine fermented in steel tank, causing production of different secondary aromas and different relative flavors.

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Integration of Liquid Chromatography with Immunoassay: An Approach Combining the Strengths of Both Methods

Journal of AOAC International ◽

10.1093/jaoac/77.5.1275 ◽

1994 ◽

Vol 77 (5) ◽

pp. 1275-1287 ◽

Cited By ~ 7

Author(s):

Petra M Krämer ◽

Qing X Li ◽

Bruce D Hammock

Keyword(s):

Liquid Chromatography ◽

Sensitivity And Specificity ◽

Immunosorbent Assay ◽

Uv Detection ◽

Enzyme Linked Immunosorbent Assay ◽

Multiresidue Analysis ◽

Selective Method ◽

Separation Power ◽

Immunochemical Detection ◽

Very High

Abstract The integration of liquid chromatography (LC) with immunochemical detection combines the superior separation power of LC and the sensitivity and specificity of immunoassays. This approach is shown with 3 LC systems (Perkin-Elmer, C18 RP, 4.6 mm; Varian, C18 RP, 1 mm microbore; Michrom, C18 RP, 1 mm microbore) Integrated with an enzyme-linked immunosorbent assay (ELISA) selective for five 4-nitrophenols. The nitrophenols were separated with the 3 LC systems with isocratic runs of 15 to 20 min. Microbore LC separation showed a 10-20 times reduction in solvent amount compared to conventional separation. LC–immunoassay was about 8- to 10-fold more sensitive compared with LC with UV detection. Integrated LC–immunoassay proved to be a very selective method when 2-methylphenol was injected with an equimolar mixture of 2-amino-4-nitrophenol and 3-methyl-4-nrtrophenol; 2-methy I phenol does not crossreact with the serum used. Only 2 peaks could be seen in the detection, even when 2-methylphenol was present in very high amounts (3000 pmol). Further, the EUSA-LC detection proved to be selective and sensitive for complex matrixes. 2-Amlno-4-nitrophenol was clearly identified in spiked extracts of soil and plant, even when a very small amount (2.4 ng) was injected. Although LC–immunoassay is more labor intensive than LC with UV detection, it offers great advantages in multiresidue analysis and is generally applicable for peak confirmation.

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Pesticide Multiresidue Analysis of 303 Compounds Using Supercritical Fluid Extraction

Analytical Sciences ◽

10.2116/analsci.22.1473 ◽

2006 ◽

Vol 22 (11) ◽

pp. 1473-1476 ◽

Cited By ~ 21

Author(s):

Yukiko ONO ◽

Takashi YAMAGAMI ◽

Takeshi NISHINA ◽

Toshiaki TOBINO

Keyword(s):

Supercritical Fluid Extraction ◽

Supercritical Fluid ◽

Fluid Extraction ◽

Multiresidue Analysis

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Development and validation of an analytical method for the multiresidue analysis of pesticides in sesame seeds using liquid- and gas chromatography with tandem mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2021.462346 ◽

2021 ◽

pp. 462346

Author(s):

Raviraj Shinde ◽

Anita Pardeshi ◽

Manisha Dhanshetty ◽

Michelangelo Anastassiades ◽

Kaushik Banerjee

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Tandem Mass Spectrometry ◽

Analytical Method ◽

Tandem Mass ◽

Multiresidue Analysis ◽

Sesame Seeds ◽

Development And Validation

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Dilution of QuEChERS Extracts Without Cleanup Improves Results in the UHPLC-MS/MS Multiresidue Analysis of Pesticides in Tomato

Food Analytical Methods ◽

10.1007/s12161-020-01921-1 ◽

2021 ◽

Author(s):

Fabiane M. Stringhini ◽

Lucila C. Ribeiro ◽

Graziela I. Rocha ◽

Juliana D. de B. Kuntz ◽

Renato Zanella ◽

...

Keyword(s):

Matrix Effect ◽

Practical Method ◽

Analysis Method ◽

Multiresidue Analysis ◽

Limit Of Quantification ◽

Chromatography Tandem Mass Spectrometry ◽

The Matrix ◽

Liquid Chromatography Tandem Mass ◽

Ultrahigh Performance Liquid Chromatography ◽

Positive Results

AbstractTomato is well-known to be one of the most cultivated and consumed vegetables worldwide and frequently contain pesticide residues. Therefore, a simple multiresidue method was established and validated to determine 129 pesticides and metabolites in tomato samples using a modified acetate QuEChERS without cleanup for sample preparation and determination by ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). Dilution of the raw extract in different proportions of mobile phase was evaluated and a dilution of 10 times presented adequate results improving analysis performance while minimizing the matrix effect. Validation performed according to SANTE guideline presented satisfactory results. Practical method limit of quantification was 0.01 mg kg−1 for most compounds. Recoveries between 70 and 120% with precision ≤ 20% were found for most compounds and spike levels evaluated. Matrix effect results were not significant for most part of compounds. Method proved to be simple, robust, and effective to be applied in routine analysis. Method applicability was performed by analysis of samples commercialized in Brazil and positive results were found demonstrating the importance of the proposed method.

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