scholarly journals African Adansonia digitata fruit pulp (baobab) modifies provitamin A carotenoid bioaccessibility from composite pearl millet porridges

2019 ◽  
Vol 57 (4) ◽  
pp. 1382-1392 ◽  
Author(s):  
Hawi Debelo ◽  
Cheikh Ndiaye ◽  
Johanita Kruger ◽  
Bruce R. Hamaker ◽  
Mario G. Ferruzzi
Keyword(s):  
Pearl Millet ◽  
Provitamin A ◽  
Fruit Pulp ◽  
Adansonia Digitata

Comprehensive Metabolomic, Lipidomic and Pathological Profiles of Baobab (Adansonia digitata) Fruit pulp Extracts in Diabetic Rats

2021 ◽  
pp. 114139
Author(s):  
Mona A. Mohammed ◽  
Hanan Naeim Attia ◽  
Souad E. El-Gengaihi ◽  
Yousreya A. Maklad ◽  
Kawkab A. Ahmed ◽  
...  
Keyword(s):  
Diabetic Rats ◽  
Fruit Pulp ◽  
Adansonia Digitata

scholarly journals Phytochemical Profile, Antioxidant and Antidiabetic Activities of Adansonia digitata L. (Baobab) from Mali, as a Source of Health-Promoting Compounds

Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3104 ◽  
Author(s):  
Alessandra Braca ◽  
Chiara Sinisgalli ◽  
Marinella De Leo ◽  
Beatrice Muscatello ◽  
Pier Luigi Cioni ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Content ◽  
Geographic Region ◽  
Major Constituent ◽  
Total Phenolic ◽  
Fruit Pulp ◽  
Adansonia Digitata ◽  
Chemical Profiles ◽  
Health Promoting ◽  
Promising Source

Background: Adansonia digitata L. (Malvaceae), also known as baobab, is a tree attracting recent interest especially due to the high nutritional value of the fruit pulp. However, few studies are reported on the secondary metabolite content, showing high variability depending on the geographic region. Methods: In this study, the chemical profiles of Malian commercial baobab fruits and leaves, focused on phenolic content, were investigated by HPLC coupled with a photodiode array (PDA)/UV and an electrospray ionization (ESI) mass spectrometer (MS) and gas chromatography (GC)/MS. In addition, the extracts of fruit pulps obtained from three different markets (Fruits 1, 2, and 3) were evaluated for their total phenolic content (TPC), antioxidant activity and α-glucosidase inhibition. Results: Baobab fruit pulps were found to be rich in procyanidins and flavonol glycosides, with tiliroside as the major constituent. The baobab leaves showed a similar profile respect to the fruits, but with more detected phenolics. All fruit pulp extracts exerted antioxidant activity (highest for Fruit 3) and higher α-glucosidase inhibition than acarbose used as standard. Conclusions: This study confirmed the variability of baobab with different origins and indicated Malian species baobab as a promising source of health-promoting substances.

Antidiarrhoeal Activity Of Ethanolic Extract Of Adansonia Digitata Fruit Pulp In Rats.

2013 ◽  
Vol 3 (6) ◽  
pp. 172 ◽  
Author(s):  
Maha Abdelrahim ◽  
Babiker Elamin ◽  
Dalia Khalil ◽  
Samia Badwi
Keyword(s):  
Ethanolic Extract ◽  
Fruit Pulp ◽  
Adansonia Digitata

scholarly journals Peptic Ulcer Healing Activity of Fruit Pulp Extract and Seed Oil of Adansonia digitata Linn

2019 ◽  
Vol 11 (05) ◽  
Author(s):  
Kajal Kamalso Malgave ◽  
Nilofar Shahnwaj Naikwade ◽  
Padma Laxmikant Ladda ◽  
Tabbasum S. Shikalgar ◽  
Sudhir S. Patil
Keyword(s):  
Secondary Metabolites ◽  
Seed Oil ◽  
Enzyme Level ◽  
Histopathological Study ◽  
Antiulcer Activity ◽  
Marker Enzyme ◽  
Fruit Pulp ◽  
Adansonia Digitata ◽  
Ulcer Index ◽  
Standard Drug

Adansonia digitata (AD) Linn has been used to cure PU in Ayurveda but its efficacy has not been validated. The current study was so carried out to evaluate the antiulcer activity of ethanolic extract of Adansonia digitata fruit pulp (ADFP), n hexane extract of Adansonia digitata seed oil (ADSO) and their combination (ADFP+ADSO) in rats. The effect of AD on gastric ulcer in pylorus ligation induced and ethanol induced models was studied using doses [ADFO (500 mg/kg), ADSO (300 mg/kg) and combination of ADFP and ADSO] for 10 days. Omeprazole (10 mg/kg) were used as the standard drug. Depending on the model, outcomes measures were gastric volume, pH, free acidity, total acidity, ulcer index, percentage inhibition of ulcer index, protein, pepsin, mucus, antioxidant marker enzyme level (Superoxide dismutase, Catalase, Lipid peroxidation), morphological and Histopathological study. The result obtained with combination was set up near to the standard drug and consequence showed that the combination of ADFP and ADSO was found to be more effective than the individual extract of AD. The outcomes were statistically evaluated with the one-way ANOVA followed by the test of Dennett’s‘t’. The secondary-metabolites such as flavonoids, proteins, saponins, tannins, phenols, terpenoids, alkaloids and Fatty acids (palmitic acid, oleic acid, linoleic acid) are potent as antioxidant, antiulcer and anti-inflammatory. The finding of this reading confirmed that AD has antiulcer activity due to 1 or more of the secondary-metabolites present in it. Therefore, this study validates its antiulcer use in Ayurveda. Future investigation on separation of specific phytochemicals and elucidate MOA are needed.

scholarly journals Phytochemical Screening and Hepatoprotective Potential of Aqueous Fruit Pulp Extract of Adansonia digitata against CCL4 Induced Liver Damage in Rats

2020 ◽  
pp. 12-21
Author(s):  
A. M. Sa’id ◽  
A. H. Musa ◽  
J. A. Mashi ◽  
F. U. Maigari ◽  
M. N. Nuhu
Keyword(s):  
Aqueous Extract ◽  
Liver Damage ◽  
Serum Levels ◽  
Health Science ◽  
Fruit Pulp ◽  
Medical Sciences ◽  
Adansonia Digitata ◽  
Hepatoprotective Effects ◽  
Dose Dependent ◽  
Basic Medical

Aim: The current study was carried out to evaluate the hepatoprotective effects of aqueous extract of Adansonia digitata fruit pulp on carbon tetrachloride (CCl4) induced liver damage in  rats. Place and Duration of Study: Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Science, between November 2017 and January 2018. Methodology: A. digitata fruit pulp was extracted by maceration using water; and a concentration of 100 mg/ml was used. Two doses of the aqueous extract (200 mg/kg and 300 mg/kg) and Livoline (25 mg/kg) were used to investigate their hepatoprotective effects on CCl4-induced hepatotoxicity in rats. Results: The two doses of the plant extract showed dose-dependent hepatoprotective effect on CCl4-induced hepatotoxicity, as evident by the significant reduction (P<0.05) in serum levels of AST, ALT, ALP and bilirubin along with the improved histopathological liver sections compared to CCl4-treated animals. Conclusion: Due to its hepatoprotective potentials, A. digitata extract may be used to develop standard treatment drugs against some liver disorders when it is further evaluated through extensive researches.

scholarly journals Hydromethanolic Extracts from Adansonia digitata L. Edible Parts Positively Modulate Pathophysiological Mechanisms Related to the Metabolic Syndrome

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2858
Author(s):  
Stefania Cicolari ◽  
Marco Dacrema ◽  
Arold Jorel Tsetegho Sokeng ◽  
Jianbo Xiao ◽  
Achille Parfait Atchan Nwakiban ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Biological Properties ◽  
Fruit Pulp ◽  
Adansonia Digitata ◽  
Leaf Extracts ◽  
Beneficial Effects ◽  
The Metabolic Syndrome ◽  
Triglyceride Accumulation ◽  
Edible Parts ◽  
Alpha Glucosidase

Metabolic syndrome includes a cluster of risk factors for many pathological conditions, including hyperglycemia, abdominal obesity, hyperlipidemia, and hypertension. Adansonia digitata L. (also known as baobab) is used in traditional African Medicine and recent studies showed that it improves the metabolism of carbohydrates and lipids. The aim of this study is to investigate the mechanisms of action associated with the beneficial effects of extracts from the edible parts of baobab (fruit pulp, leaves, raw and toasted seeds), evaluating their inhibitory activity against: alpha-amylase, alpha-glucosidase, angiotensin-converting enzyme, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, and pancreatic lipase. Baobab fruit pulp and leaf extracts resulted to be the most active ones and were then tested on the differentiation process of SW-872 human liposarcoma cells to mature adipocytes. The addition of these latter extracts did not affect triglyceride accumulation, indicating a neutral impact on this parameter. The findings here reported help to explain the growing amount of evidence on the biological properties of baobab and provide suggestions about their use in food and nutraceutical fields.

scholarly journals HIV-1 REVERSE TRANSCRIPTASE AND PROTEASE ASSAY OF METHANOLIC EXTRACTS OF ADANSONIA DIGITATA L.

2016 ◽  
Vol 8 (9) ◽  
pp. 124 ◽  
Author(s):  
Amrish Sharma ◽  
Vinod Rangari
Keyword(s):  
Reverse Transcriptase ◽  
Leaf Extract ◽  
Bark Extract ◽  
Root Bark ◽  
Fruit Pulp ◽  
Adansonia Digitata ◽  
Methanolic Extracts ◽  
Anti Hiv ◽  
Protease Assay ◽  
Hiv 1

<p><strong>Objective</strong>:<strong> </strong>Anti-HIV activity studies of methanolic extracts of <em>Adansonia digitata</em> L. leaves, root bark and fruit pulp.<strong></strong></p><p><strong>Methods</strong>:<strong> </strong>Methanolic extracts of <em>A. digitata</em> were tested for HIV enzyme inhibitory activity against HIV-1 reverse transcriptase (RT) and HIV-1 protease (PR). HIV-1 RT assay was performed using<em> </em>non-radioactive HIV-RT colorimetric ELISA kit while the HIV-1 PR assay was performed using a fluorogenic octapeptide substrate, HIV-FRET (fluorescence resonance energy transfer) and a recombinant HIV-1 protease solution (AnaSpec Inc., USA).</p><p><strong>Results</strong>:<strong> </strong>The percentage inhibition of controls and <em>A. digitata </em>leaves, root bark and fruit pulp extracts were calculated relative to uninhibited HIV-1 RT and PR in 2% DMSO. The results of the HIV-1 RT assay indicated 26.5% inhibition by root bark extract (50 µg/ml) and 12.2% inhibition by leaf extract while the fruit pulp extract (100 µg/ml) has shown only 5.9% inhibition as compared to standard Nevirapine (100 nM) 27.5% inhibition.</p><p>In the case of HIV-protease assay, leaf extract and fruit pulp extract (50 µg/ml) has shown quite high inhibition (≥ 50%) to the extent of 75% and 74% respectively which is very significant. The root bark extract has shown 35% inhibition.</p><p><strong>Conclusion: </strong>Methanolic extract of the leaves, root bark and fruit pulp of <em>A. digitata</em> has shown low anti-HIV-1 RT but significant PR activity. HIV-1 RT activity of root bark extract and HIV-1 PR activity of fruit pulp extract indicates the potential of the plant as an anti-HIV agent. </p>

Xylogalacturonan-enriched pectin from the fruit pulp of Adansonia digitata: Structural characterization and antidepressant-like effect

2021 ◽  
Vol 262 ◽  
pp. 117946
Author(s):  
O.A. Patova ◽  
A. Luаnda ◽  
N.M. Paderin ◽  
S.V. Popov ◽  
J.J. Makangara ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Fruit Pulp ◽  
Adansonia Digitata
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