From folk medicine to functional food: a review on the bioactive components and pharmacological properties of citrus peels

2018 ◽  
Vol 18 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Ayokunle O. Ademosun ◽  
Ganiyu Oboh ◽  
Tosin A. Olasehinde ◽  
Opeyemi O. Adeoyo
Keyword(s):  
Functional Food ◽  
Folk Medicine ◽  
Pharmacological Properties ◽  
Bioactive Components ◽  
Citrus Peels

scholarly journals Botanical, Chemical and Pharmacological Properties of Artocarpus lakoocha (Monkey Fruit): A Review

2020 ◽  
Author(s):  
Arun Kumar Gupta ◽  
Urbi Pathak ◽  
Manisha Medhi ◽  
Andrea Mastinu ◽  
Mukesh S. Sikarwar ◽  
...  
Keyword(s):  
Chronic Diseases ◽  
Bioactive Compounds ◽  
Functional Food ◽  
Large Family ◽  
Food Products ◽  
Pharmacological Properties ◽  
Bioactive Components ◽  
Inhibitory Factors

Artocarpus are members of the Moraceae family who are believed to be a large family comprises of nearly 60 genera and about 1400 species. The most important genus of the Moraceae family is Ficus, Morus and Artocarpus. The extract and bioactive compounds from bark, leaves, seeds and pericarp of monkey fruit have shown to possess exceptional phytochemical, nutritional and valuable pharmacological properties. This fruit is capable of offering numerous inhibitory factors such as antibacterial, antitubercular, antiviral, antifungal, antiplatelet, antiarthritic, tyrosinase inhibitory and cytotoxicity. This review devotes the complete overview of pharmacological and bioactive components exclusively found in the monkey fruit and its parts. However, fruit exhibits appreciable properties, but they are still unknown as well as underutilized. The remarkable properties of plants and the modern approaches are needed for the treatment of chronic diseases, the development of drugs and functional food products, or for the improvement of properties existed ones. 

scholarly journals ETHNOBOTANICAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL PROPERTIES OF NEPENTHES SPECIES: A REVIEW

2017 ◽  
Vol 10 (11) ◽  
pp. 16 ◽  
Author(s):  
Shuaibu Babaji Sanusi ◽  
Mohd Fadzelly Abu Bakar ◽  
Maryati Mohamed ◽  
Siti Fatimah Sabran ◽  
Muhammad Murtala Mainasara
Keyword(s):  
Folk Medicine ◽  
Therapeutic Agents ◽  
Bioactive Components ◽  
Pharmacological Activities ◽  
Crude Extracts ◽  
Gastrointestinal Discomfort ◽  
Wide Range ◽  
Long Time ◽  
Phytochemical Compounds ◽  
Ethnobotanical Uses

The genus Nepenthes (Nepenthaceae) has been utilized in folk medicine for a long time in India and Southeast Asia countries. They are used in the treatment of leprosy, cholera, night blindness, gastrointestinal discomfort, dysentery, stomachache, and bed-wetting among others. This review highlights the ethnobotanical uses, phytochemicals, and pharmacological activities of both crude extracts and pure bioactive compounds of Nepenthes spp. The phytochemical compounds isolated from Nepenthes species include flavonoids, terpenoids, tannins, alkaloids, and steroids among other phytochemicals. A wide range of pharmacological activities was exhibited by the crude extracts and pure bioactive components such as antibacterial, antifungal, antimalarial antioxidant, antidiabetic, antiosteoporotic, anti-inflammatory, cytotoxicity, and hypolipidemic activities. This review revealed that many active compounds are present in Nepenthes spp. However, many pharmacological screenings such as anticancer, antiviral, wound healing, antihelminthic, antidiarrheal properties, among others have not been carried out yet. Therefore, more biological investigations and phytochemical screenings are required to fully explore the genus Nepenthes which may lead to development of new therapeutic agents.  

scholarly journals Seaweed as novel food for prevention and therapy for life style related disease

2021 ◽  
Vol 5 (1) ◽  
pp. 1
Author(s):  
Lindarsih Notowidjojo
Keyword(s):  
Cardiovascular Disease ◽  
Functional Food ◽  
Folk Medicine ◽  
Novel Food ◽  
Disease Epidemiology ◽  
Related Disease ◽  
The World ◽  
Alternative Sources ◽  
Epidemiology Studies ◽  
Prevention And Therapy

Seaweed has long been known and consumed as a functional food and folk medicine, especially in people who live in coastal areas. Research on seaweed has recently increased with the surge need for alternative sources of functional food to deal with health problems related to lifestyle, such as obesity, diabetes, hypertension and cardiovascular disease. Epidemiology studies have found that population consumed seaweed is on a regular basis have significantly less diet-related diseases.1,2 Even the largest population of old age is in Japan, which consumes the most seaweed in the world.1,3 In countries such as Japan, China, and Korea, approximately 66% of algae species have been used as a daily ingredient in their dishes for many years.

ETHNOBOTANICAL RESEARCH OF THE PERSPECTIVE MEDICINAL PLANT OFCISTANCHE SALSA (С.А. МEY.) G. BECK

Vestnik ◽  
2021 ◽  
pp. 252-255
Author(s):  
Д.К. Айдарбаев ◽  
А.Ж. Жарқынбек
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Folk Medicine ◽  
Climatic Conditions ◽  
Pharmacological Properties ◽  
Ecological Features ◽  
Wide Range ◽  
The Family ◽  
Research Recommendations

В статье рассматриваются биологические и экологические особенности цистанхе, а также предусматривается этноботанические исследования, рекомендации по рациональному использованию. Выявлены некоторые значения Cistanchе, которое произрастает в Казахстане. Определена область использования в народной медицине цистанхе из семейства Orobanchaceae. В исследовании показана роль цистанхе, как растения с широким спектром фармакологических свойств. Проведен анализ маршрутно-рекогносцировочных исследований популяции цистанхе, определены распределение, запасы и объемы ежегодных заготовок по основным расположенным флористическим районам. Проведен расчет среднего суммарного объема заготовок сырья, собранных в Прибалхашье Алматинской области. В настоящее время в результате глобального потепления климатические условия меняются, и многие виды растений вымирают. Поэтому защита и эффективное использование растений является одной из самых актуальных проблем. Также важно изучить цистанхе, используемый в народной медицине как лекарственное растение. The article discusses the biological and ecological features of cistanche, as well as provides for ethnobotanical research, recommendations for rational use. Some values of Cistanche, which grows in Kazakhstan, are revealed. The scope of use in folk medicine of cistanha from the family Orobanchaceae is determined. The study shows the role of cistanche as a plant with a wide range of pharmacological properties. Conducted analysis of route-reconnaissance studies of cisterna populations, determined the distribution, stock and volumes of annual preparations for the main floristic areas. Calculated the average total volume of raw materials collected in the Balkhash region of Almaty region. As a result of global warming, climatic conditions are changing and many plant species are dying. Therefore, the protection and efficient use of plants is one of the most pressing problems. It is also important to study the tanks used in folk medicine as a medicinal plant.

Polysaccharides as Bioactive Components of Functional Food

2015 ◽  
pp. 133-158 ◽  
Author(s):  
Patricia Peso-Echarri ◽  
Carlos Alberto González-Bermúdez ◽  
Gaspar Ros-Berruezo ◽  
Carmen Martínez-Graciá ◽  
Carmen Frontela-Saseta
Keyword(s):  
Functional Food ◽  
Bioactive Components

scholarly journals Cocoa Shell as a Step Forward to Functional Chocolates—Bioactive Components in Chocolates with Different Composition

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5470
Author(s):  
Veronika Barišić ◽  
Milica Cvijetić Stokanović ◽  
Ivana Flanjak ◽  
Kristina Doko ◽  
Antun Jozinović ◽  
...  
Keyword(s):  
Functional Food ◽  
Bioactive Components ◽  
Nutritional Properties ◽  
Frap Assay ◽  
Total Polyphenol ◽  
Antioxidant Power ◽  
Cocoa Butter Equivalents ◽  
Dairy Ingredients ◽  
Ferric Reducing Antioxidant Power ◽  
Cocoa Shell

Chocolate is considered as both caloric and functional food. Its nutritional properties may be improved by addition of fiber; however, this may reduce polyphenols content. The aim of this research was to determine the influence of cocoa shell addition (as a source of fiber) and its combination with different ingredients (cocoa butter equivalents (CBE), emulsifiers, dairy ingredients) on polyphenols of dark and milk chocolates. Total polyphenol (TPC) and total flavonoid (TFC) contents were determined spectrophotometrically, identification and quantification of individual compounds by high pressure liquid chromatography and antioxidant capacity by ferric reducing antioxidant power (FRAP) assay. Results showed that even though addition of cocoa shell to chocolate results in reduced contents of TPC, TFC, and individual compounds, it is not significant compared to ones reported by other authors for commercial chocolates. Other ingredients influence determined values for all investigated parameters; however, additional research is needed to reveal exact mechanisms and implications.

Halimium halimifolium: From the Chemical and Functional Characterization to a Nutraceutical Ingredient Design

Planta Medica ◽  
2019 ◽  
Vol 85 (11/12) ◽  
pp. 1024-1033 ◽  
Author(s):  
Khawla Kerbab ◽  
Francesca Sansone ◽  
Lahcene Zaiter ◽  
Tiziana Esposito ◽  
Rita Celano ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Folk Medicine ◽  
Oral Intake ◽  
In Vitro Dissolution ◽  
Bioactive Components ◽  
Ph Change ◽  
Laser Scattering ◽  
Aerial Parts ◽  
Derivatives Of

Abstract Halimium halimifolium (Hh) is a shrub used in Algerian folk medicine to treat gastrointestinal pain. An UHPLC-PDA-ESI/MSn method was developed to identify the metabolic profile of the traditionally used infusion (Hh-A) from the aerial parts. The structures of flavanols were confirmed by NMR analysis after the isolation procedure from a hydrohalcolic extract (Hh-B) that also allowed for the identification of phenolic acids, an aryl butanol glucoside, and different derivatives of quercetin, myricetin, and kaempferol. Tiliroside isomers were the chemical markers of Hh-A and Hh-B (54.33 and 36.00 mg/g, respectively). Hh-A showed a significant scavenging activity both against the radicals 1,1-diphenyl-2-picrylhydrazyl and 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (EC50 = 10.49 µg/mL and TEAC value = 1.98 mM Trolox/mg infusion) and the lipopolysaccharide-induced reactive oxygen species release in A375 and HeLa cells. Moreover, the antihyperglycemic properties, by inhibiting the α-amylase and α-glucosidase enzymes (IC50 = 0.82 mg/mL and 25.01 µg/mL, respectively), were demonstrated. To upgrade the therapeutic effect, a microencapsulation process is proposed as a strategy to optimize stability, handling, and delivery of bioactive components, avoiding the degradation and loss of the biological efficacy after oral intake. Hh-loaded microparticles were designed using cellulose acetate phthalate as the enteric coating material and spray drying as a production process. The results showed a satisfactory process yield (67.9%), encapsulation efficiency (96.7%), and micrometric characteristics of microparticles (laser-scattering, fluorescent, and scanning electron microscopy). In vitro dissolution studies (USPII-pH change method) showed that Hh-loaded microparticles are able to prevent the release and degradation of the bioactive components in the gastric tract, releasing them into the intestinal environment.

scholarly journals Traditional Uses, Phytochemical and Pharmacological Properties of Ficus auriculata: A Review

2021 ◽  
Vol 11 (3) ◽  
pp. 163-169
Author(s):  
Garima Tamta ◽  
Nisha Mehra ◽  
S. Tandon
Keyword(s):  
Amino Acids ◽  
Leaf Extract ◽  
Folk Medicine ◽  
Farming System ◽  
Pharmacological Properties ◽  
Glutathione Level ◽  
Fruit Extract ◽  
Commercial Purpose ◽  
Medicinal Properties ◽  
Histopathological Studies

Ficus auriculata belongs to family Moraceae. It is also known as Elephant earfig tree because of its large leaves. In India  it is commonly known as Timla, Gular , Tirmal, Timal, Timbal, Tremal, Trimmal.. The plants are mainly distributed in temperate, tropical and subtropical regions of about 1800–2600 m altitude. It is native to Asia, especially in India, China, Nepal, Bhutan, Pakistan, Myanmar, Thailand, Vietnam, Malaysia.The plants have great ethnomedicinal importance and are used in traditional folk medicine for curing many ailments in humans. The plants rich in Phytoconstituent  e.g.  alkaloids, carbohydrates, saponins, glycosides, phytosterols, resins, phenols, tannins, diterpenes, flavonoids, proteins, and amino acids which are present in barks, leaves and fruit extract. The review reveals that huge numbers of phytochemicals which was  isolated from the plant possesses the biological and pharmacological properties are shown by the  bark, leaves and fruits extract of Ficus auriculata i.e antioxidant, antibacterial, hepatoprotective, histopathological studies, toxicity activity,  anticancerous, antidiabatic, hyperlipidemic, hyperglycemic and anti-inflammatory. Leaf extract has also an important role in Glutathione  level in cardiac and also used as fodder for farming system,  for medicinal properties and for further commercial purpose. Keywords: Ficus auriculata, Phytochemistry, Pharmacological Activity, Herbal Medicine

scholarly journals Ethanobotanical, phytochemical and pharmacological properties of Zizyphus nummularia (Burm. F.): A Review

2018 ◽  
Vol 10 (3) ◽  
pp. 137
Author(s):  
Babita Aggarwal ◽  
Pankaj Sharma ◽  
HS Lamba
Keyword(s):  
Mental Retardation ◽  
Folk Medicine ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Anti Inflammatory

<p><em>Zizyphus nummularia</em> (Burm. F.), Family: Rhamnaceae, is widely distributed in dry regions of India. It is a bushy weed used as folk medicine. The plant is valued for its nutritional edible fruits. Traditionally, it is used in mental retardation, fever, diarrhea, dysentery. The plant has been evaluated for various pharmacological activities such as anti-inflammatory, anthelmintic, antibacterial, antifertility activity. Present review discusses phytochemistry and pharmacological aspects of the drug.</p>

scholarly journals A review of pears (Pyrus spp.), ancient functional food for modern times

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sung-Yong Hong ◽  
Ephraim Lansky ◽  
Sam-Sog Kang ◽  
Mihi Yang
Keyword(s):  
Functional Food ◽  
Communicable Disease ◽  
Folk Medicine ◽  
Protective Effects ◽  
Modern Times ◽  
Carcinogenic Effects ◽  
Underlying Diseases ◽  
Non Communicable Disease

Abstract Background Pears have been world-widely used as a sweet and nutritious food and a folk medicine for more than two millennia. Methods We conducted a review from ancient literatures to current reports to extract evidence-based functions of pears. Results We found that pears have many active compounds, e.g., flavonoids, triterpenoids, and phenolic acids including arbutin, chlorogenic acid, malaxinic acid, etc. Most of researchers agree that the beneficial compounds are concentrated in the peels. From various in vitro, in vivo, and human studies, the medicinal functions of pears can be summarized as anti-diabetic,-obese, −hyperlipidemic, −inflammatory, −mutagenic, and -carcinogenic effects, detoxification of xenobiotics, respiratory and cardio-protective effects, and skin whitening effects. Therefore, pears seem to be even effective for prevention from Covid-19 or PM2.5 among high susceptible people with multiple underlying diseases. Conclusion For the current or post Covid-19 era, pears have potential for functional food or medicine for both of communicable and non-communicable disease.

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