Graeco Latin Square Designs with Neighbor Effects

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Sobita Sapam ◽  
Bikas Kumar Sinha
2020 ◽  
Vol 36 (2) ◽  
pp. 296-302 ◽  
Author(s):  
Luke J. Hearne ◽  
Damian P. Birney ◽  
Luca Cocchi ◽  
Jason B. Mattingley

Abstract. The Latin Square Task (LST) is a relational reasoning paradigm developed by Birney, Halford, and Andrews (2006) . Previous work has shown that the LST elicits typical reasoning complexity effects, such that increases in complexity are associated with decrements in task accuracy and increases in response times. Here we modified the LST for use in functional brain imaging experiments, in which presentation durations must be strictly controlled, and assessed its validity and reliability. Modifications included presenting the components within each trial serially, such that the reasoning and response periods were separated. In addition, the inspection time for each LST problem was constrained to five seconds. We replicated previous findings of higher error rates and slower response times with increasing relational complexity and observed relatively large effect sizes (η2p > 0.70, r > .50). Moreover, measures of internal consistency and test-retest reliability confirmed the stability of the LST within and across separate testing sessions. Interestingly, we found that limiting the inspection time for individual problems in the LST had little effect on accuracy relative to the unconstrained times used in previous work, a finding that is important for future brain imaging experiments aimed at investigating the neural correlates of relational reasoning.


2011 ◽  
Vol 16 (1) ◽  
Author(s):  
Sorta Basar Ida Simanjuntak ◽  
Sukarti Moeljopawiro ◽  
Wayan Tunas Artama ◽  
Subagus Wahyuono

Toksoplasmosis adalah penyakit yang disebabkan oleh infeksi Toxoplasma gondii. Penyakit ini sangat berbahaya pada hewan maupun manusia. Toksoplasmosis sampai sekarang masih sulit ditanggulangi. Untuk itu, dicari akternatif dengan cara pemberian imunostimulator, seperti Spirulina platensis. Tujuan penelitian ini adalah untuk mengetahui ekstrak Spirulina platensis yang paling potensial meningkatkan respon imun humoral dan mengetahui dosis Spirulina platensis yang efektif dalam meningkatkan respons imun humoral. Rancangan penelitian adalah Rancangan Acak Lengkap pola Faktorial. Faktor pertama adalah jenis ekstrak (ekstrak etil asetat, ekstrak air dan Spirulina platensis murni). Faktor kedua adalah dosis ekstrak (0, 5, 10, 15 mg/ekor mencit). Hasil penelitian menunjukkan bahwa ekstrak etil asetat dengan dosis 5 mg/ekor mencit adalah yang terbaik meningkatkan respon imun humoral. Uji lanjut dengan Latin Square Design (LSD) menunjukkan bahwa terdapat interaksi antara jenis ekstrak dan dosis ekstrak.


2019 ◽  
Vol 2 (1) ◽  
pp. 9-13
Author(s):  
Zaim Anshari ◽  
Chrismis Novalinda Ginting ◽  
Linda Chiuman ◽  
Yuliani Mardiati Lubis

This study aims to determine whether mangosteen rind extract (in the form of ethanol extract/EE) can be used as an anti-diarrhea drug after compared with other anti-diarrhea substances in three experimental groups. This research is an in vitro experimental study using adult male guinea pigs weighing 400-600 gr through the standard method of Magnus with the Latin square controlled experiment design. The study was conducted at the Pharmacology and Toxicology Laboratory of the Faculty of Pharmacy, University of North Sumatra. The results showed that the contraction of ileum in Ach with Atp + Ach compared the difference in contraction of ileum Ach with EE + Ach showed the difference in difference between the two contractions of the ileum was significant, the contraction of ileum in His with Dip + His compared indifference in contraction of ileum His with EE + His showed a difference indifference. the two ileal contractions are significant, the ileal contraction in the bar with Papa + Bar compared to the difference between the ileum bar contraction with EE + Bar shows no difference in the difference between the two ileum contractions. The conclusion is that the Mangosteen Skin Ethanol Extract works similarly to Papaverine Hydrochloride which is an antidiarrheal drug used to relax smooth muscles so that it can also make blood vessels dilate by relaxing smooth muscles in the walls of blood vessels.


1999 ◽  
Vol 1999 ◽  
pp. 133-133 ◽  
Author(s):  
B M L McLean ◽  
J J Hyslop ◽  
A C Longland ◽  
D Cuddeford ◽  
T Hollands

Processed cereals are used routinely in diets for equines but little information is available on how physical processing affects the digestibility of cereals in equines. This study examines the effects of three physical processing methods (rolling, micronisation and extrusion) on the in vivo apparent digestibility of barley fed to ponies.Three mature caecally-fistulated Welsh-cross pony geldings, (LW 284kg ± 3.8kg) were used in a 3 x 4 incomplete latin square changeover design experiment consisting of four 21 day periods. Each period comprised a sixteen day adaptation phase and a five day recording phase when apparent digestibility in vivo was determined. Ponies were offered 4kg dry matter (DM) per day of either 100% hay cubes (HC) or one of three diets consisting of a 50:50 barley:hay cubes mix. The barley in the mixed diets was either rolled barley (RB), micronised barley (MB) or extruded barley (EB). Diets were offered in 2 equal meals per day fed at 09:00 and 17:00 hours respectively.


BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e023850
Author(s):  
Catherine S Wall ◽  
Rose S Bono ◽  
Rebecca C Lester ◽  
Cosima Hoetger ◽  
Thokozeni Lipato ◽  
...  

IntroductionIn the USA, Food and Drug Administration regulations prohibit the sale of flavoured cigarettes, with menthol being the exception. However, the manufacture, advertisement and sale of flavoured cigar products are permitted. Such flavourings influence positive perceptions of tobacco products and are linked to increased use. Flavourings may mask the taste of tobacco and enhance smoke inhalation, influencing toxicant exposure and abuse liability among novice tobacco users. Using clinical laboratory methods, this study investigates how flavour availability affects measures of abuse liability in young adult cigarette smokers. The specific aims are to evaluate the effect of cigar flavours on nicotine exposure, and behavioural and subjective measures of abuse liability.Methods and analysesParticipants (projected n=25) are healthy smokers of five or more cigarettes per day over the past 3 months, 18–25 years old, naive to cigar use (lifetime use of 50 or fewer cigar products and no more than 10 cigars smoked in the past 30 days) and without a desire to quit cigarette smoking in the next 30 days. Participants complete five laboratory sessions in a Latin square design with either their own brand cigarette or a session-specific Black & Mild cigar differing in flavour (apple, cream, original and wine). Participants are single-blinded to cigar flavours. Each session consists of two 10-puff smoking bouts (30 s interpuff interval) separated by 1 hour. Primary outcomes include saliva nicotine concentration, behavioural economic task performance and response to various questionnaire items assessing subjective effects predictive of abuse liability. Differences in outcomes across own brand cigarette and flavoured cigar conditions will be tested using linear mixed models.Ethics and disseminationThe Virginia Commonwealth University Institutional Review Board approved the study (VCU IRB: HM20007848). Dissemination channels for study findings include scientific journals, scientific meetings, and policy briefs.Trial registration numberNCT02937051.


2019 ◽  
Vol 97 (7) ◽  
pp. 3056-3070 ◽  
Author(s):  
Emily A Petzel ◽  
Evan C Titgemeyer ◽  
Alexander J Smart ◽  
Kristin E Hales ◽  
Andrew P Foote ◽  
...  

AbstractTwo experiments were conducted to measure rates of ruminal disappearance, and energy and nutrient availability and N balance among cows fed corn husks, leaves, or stalks. Ruminal disappearance was estimated after incubation of polyester bags containing husks, leaves or stalks in 2 separate ruminally cannulated cows in a completely randomized design. Organic matter (OM) that initially disappeared was greatest for stalks and least for husks and leaves (P < 0.01), but amounts of NDF that initially disappeared was greatest for husks, intermediate for stalks, and least for leaves (P < 0.01). Amounts of DM and OM that slowly disappeared were greatest in husks, intermediate in leaves, and least in stalks (P < 0.01). However, amounts of NDF that slowly disappeared were greatest in leaves, intermediate in husks, and least in stalks (P < 0.01). Rate of DM and OM disappearance was greater for leaves, intermediate for husks and least for stalks, but rate of NDF disappearance was greatest for stalks, intermediate for leaves, and least for husks (P < 0.01). Energy and nutrient availability in husks, leaves, or stalks were measured by feeding ruminally cannulated cows husk-, leaf-, or stalk-based diets in a replicated Latin square. Digestible energy lost as methane was less (P = 0.02) when cows were fed leaves in comparison to husks or stalks, and metabolizable energy (Mcal/kg DM) was greater (P = 0.03) when cows were fed husks and leaves compared with stalks. Heat production (Mcal/d) was not different (P = 0.74) between husks, leaves, or stalks; however, amounts of heat produced as a proportion of digestible energy intake were less (P = 0.05) among cows fed leaves in comparison to stalks or husks. Subsequently, there was a tendency (P = 0.06) for net energy available for maintenance from leaves (1.42 Mcal/kg DM) to be greater than stalks (0.91 Mcal/kg DM), and husks (1.30 Mcal/kg DM) were intermediate. Nitrogen balance was greater when cows were fed leaves, intermediate for husks, and least for stalks (P = 0.01). Total tract digestion of NDF was greater (P < 0.01) for husks and leaves compared with stalks. Husks had greater (P = 0.04) OM digestibility in comparison to stalks, and leaves were intermediate. Apparently, greater production of methane from husks in comparison to leaves limited amounts of energy available for maintenance from husks even though total-tract nutrient digestion was greatest when cows were fed husks or leaves.


Mathematics ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 285
Author(s):  
Laura M. Johnson ◽  
Stephanie Perkins

This communication provides a discussion of a scheme originally proposed by Falcón in a paper entitled “Latin squares associated to principal autotopisms of long cycles. Applications in cryptography”. Falcón outlines the protocol for a cryptographical scheme that uses the F-critical sets associated with a particular Latin square to generate access levels for participants of the scheme. Accompanying the scheme is an example, which applies the protocol to a particular Latin square of order six. Exploration of the example itself, revealed some interesting observations about both the structure of the Latin square itself and the autotopisms associated with the Latin square. These observations give rise to necessary conditions for the generation of the F-critical sets associated with certain autotopisms of the given Latin square. The communication culminates with a table which outlines the various access levels for the given Latin square in accordance with the scheme detailed by Falcón.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 176-176
Author(s):  
B V Le Thanh ◽  
J R R Bergstrom ◽  
J D Hahn ◽  
L F Wang ◽  
E Beltranena ◽  
...  

Abstract Feed enzymes may ameliorate reduced nutrient and energy digestibility in nursery pigs. The objective was to test effects of super-dosing phytase and fiber-degrading enzymes on digestibility of DM, GE, CP, AA, and Ca. We tested supplementing a super dose (added 1,500 FYT/kg) of phytase (Ronozyme Hi-Phos) with or without carbohydrase cocktail that contained 85 FXU β-xylanase/kg, 587 U/g endo-1,4-β-glucanase, 513 U/g endo-1,3(4)-β-glucanase, 15,000 U/g hemicellulases, and 3,000 U/g pectinases in corn-soybean meal diets in a 2 × 2 factorial arrangement. Diets included 68% corn, 17% SBM, and a basal level of 500 FTU/kg of phytase, and were formulated to contain 2.50 Mcal/kg NE and 5.10 gSID Lys/Mcal NE. Eight ileal-cannulated nursery pigs (initial BW 10 kg) were fed 4 diets at 3.0 × maintenance DE (110 kcal per kg of BW0.75) for four 9-day periods in a double 4 × 4 Latin square. Apparent hindgut fermentation (AHF) was calculated as apparent total tract digestibility (ATTD) minus apparent ileal digestibility (AID). Interactions between super-dosing phytase and carbohydrase cocktail were observed. Supplementing either carbohydrase cocktail or super dose phytase, but not their combination, increased (P &lt; 0.05) diet AID of DM, GE, CP, and most AA by 4–5%-units. Supplementing super dose phytase increased (P &lt; 0.05) AID of P by 16%-units and ATTD of P by 10%-units. Supplementing super dose phytase or carbohydrase cocktail did not affect AID of Ca and ATTD of GE, CP, and Ca, and diet DE value. Supplementing carbohydrase cocktail without super dose phytase decreased (P &lt; 0.05) diet AHF of DM, GE, and CP. In conclusion, dietary inclusion of super dose phytase or carbohydrase cocktail increased ileal digestibility of nutrients in nursery pigs, and thereby reduced protein entering the large intestine. Additive or synergistic effects of carbohydrase cocktail and super dose phytase were not detected.


Sign in / Sign up

Export Citation Format

Share Document