scholarly journals Ectopic Banking and Implantation of an Amputated Hand

2020 ◽  
Vol 54 (5) ◽  
pp. 731-737
Author(s):  
Omid Liaghat ◽  
Zohre Shabbooie
Keyword(s):  
Body Part ◽  
Hemodynamic Instability ◽  
Tissue Loss ◽  
Body Parts ◽  
Recipient Site ◽  
First Case ◽  
Soft Tissue Loss ◽  
The Right ◽  
Hand Replantation ◽  
Standard Tests

Abstract Background Ectopic banking includes techniques and indications used to bank amputated body parts for later replantation when a body part is amputated in its entirety. Immediate replantation is sometimes impossible due to hemodynamic instability, soft tissue loss, and extensive contamination of the amputated part. The first case of temporary ectopic banking of hand implantation was reported in 2015 by Xu Zhang in China which was not completely successful. The first replantation was reported almost 54 years ago, followed by a limited number of similar cases that were not successful. Xu could not restore the useful function of the replanted hand. Purpose In this study, we reported a case of hand replantation by the banking technique. Method We carried out a hand replantation by the banking technique using the right ankle as the recipient site. Result We restored the useful function of the amputated part and evaluated the function with standard tests. Conclusion Using right ankle as recipient site in ectopic banking can be a useful approach which helps and ensures the researchers and surgeons to decide if they intend to use this method.

scholarly journals Exploring the Interaction Between Handedness and Body Parts Ownership by Means of the Implicit Association Test

2021 ◽  
Vol 15 ◽  
Author(s):  
Damiano Crivelli ◽  
Valeria Peviani ◽  
Gerardo Salvato ◽  
Gabriella Bottini
Keyword(s):  
Implicit Association Test ◽  
Motor Behavior ◽  
Body Part ◽  
Association Test ◽  
The Self ◽  
Body Parts ◽  
Implicit Association ◽  
Healthy Individuals ◽  
Animal Body ◽  
The Right

The experience of owning a body is built upon the integration of exteroceptive, interoceptive, and proprioceptive signals. Recently, it has been suggested that motor signals could be particularly important in producing the feeling of body part ownership. One thus may hypothesize that the strength of this feeling may not be spatially uniform; rather, it could vary as a function of the degree by which different body parts are involved in motor behavior. Given that our dominant hand plays a leading role in our motor behavior, we hypothesized that it could be more strongly associated with one’s self compared to its non-dominant counterpart. To explore whether this possible asymmetry manifests as a stronger implicit association of the right hand (vs left hand) with the self, we administered the Implicit Association Test to a group of 70 healthy individuals. To control whether this asymmetric association is human-body specific, we further tested whether a similar asymmetry characterizes the association between a right (vs left) animal body part with the concept of self, in an independent sample of subjects (N = 70, 140 subjects total). Our results revealed a linear relationship between the magnitude of the implicit association between the right hand with the self and the subject’s handedness. In detail, the strength of this association increased as a function of hand preference. Critically, the handedness score did not predict the association of the right-animal body part with the self. These findings suggest that, in healthy individuals, the dominant and non-dominant hands are differently perceived at an implicit level as belonging to the self. We argue that such asymmetry may stem from the different roles that the two hands play in our adaptive motor behavior.

scholarly journals The Role of Autologous Dermal Micrografts in Regenerative Surgery: A Clinical Experimental Study

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Marco Mario Tresoldi ◽  
Antonio Graziano ◽  
Alberto Malovini ◽  
Angela Faga ◽  
Giovanni Nicoletti
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Soft Tissue ◽  
Objective Assessment ◽  
Healing Process ◽  
Tissue Loss ◽  
Dermal Substitute ◽  
Recipient Site ◽  
Significant Difference ◽  
Soft Tissue Loss

The aim of the study was the objective assessment of the effectiveness of a microfragmented dermal extract obtained with Rigenera™ technology in promoting the wound healing process in an in vivo homogeneous experimental human acute surgical wound model. The study included 20 patients with 24 acute postsurgical soft tissue loss and a planned sequential two-stage repair with a dermal substitute and an autologous split-thickness skin graft. Each acute postsurgical soft tissue loss was randomized to be treated either with an Integra® dermal substitute enriched with the autologous dermal micrografts obtained with Rigenera™ technology (group A—Rigenera™ protocol) or with an Integra® dermal substitute only (group B—control). The reepithelialization rate in the wounds was assessed in both groups at 4 weeks through digital photography with the software “ImageJ.” The dermal cell suspension enrichment with the Rigenera™ technology was considered effective if the reepithelialized area was higher than 25% of the total wound surface as this threshold was considered far beyond the expected spontaneous reepithelialization rate. In the Rigenera™ protocol group, the statistical analysis failed to demonstrate any significant difference vs. the controls. The old age of the patients likely influenced the outcome as the stem cell regenerative potential is reduced in the elderly. A further explanation for the unsatisfying results of our trial might be the inadequate amount of dermal stem cells used to enrich the dermal substitutes. In our study, we used a 1 : 200 donor/recipient site ratio to minimize donor site morbidity. The gross dimensional disparity between the donor and recipient sites and the low concentration of dermal mesenchymal stromal stem cells might explain the poor epithelial proliferative boost observed in our study. A potential option in the future might be preconditioning of the dermal stem cell harvest with senolytic active principles that would fully enhance their regenerative potential. This trial is registered with trial protocol number NCT03912675.

scholarly journals Income Redistribution, Body Part Redistribution, and Respect for the Separateness of Persons

2019 ◽  
Vol 16 (3) ◽  
Author(s):  
Joseph Mazor
Keyword(s):  
Personal Identity ◽  
Body Part ◽  
Moral Authority ◽  
The Body ◽  
Labor Income ◽  
Body Parts ◽  
The Poor ◽  
Negative Rights ◽  
Separateness Of Persons ◽  
The Right

This article considers the question of why labor income may be permissibly redistributed to the poor even though non-essential body parts should generally be protected from redistribution to the infirm – the body-income puzzle.  It argues that proposed solutions that affirm self-ownership but reject ownership of labor income are unsuccessful.  And proposed solutions that grant individuals entitlements to resources based on the centrality of those resources to the individual’s personal identity are also unsuccessful.  Instead, this article defends a solution to the body-income puzzle based on a novel conception of respect for the separateness of persons.  This conception holds that the sphere of moral authority protected from interference by respect for the separateness of persons includes both the body and labor income.  And the strength of the negative rights constituting this sphere vary based on these rights' importance to the personal identity of the right-holder.  It is shown that a commitment to helping the disadvantaged tempered by this conception of respect for the separateness of persons can solve the body-income puzzle.

scholarly journals Welcoming back my arm: Affective touch increases body ownership following right hemisphere stroke

2019 ◽  
Author(s):  
Paul M. Jenkinson ◽  
Cristina Papadaki ◽  
Sahba Besharati ◽  
Valentina Moro ◽  
Valeria Gobbetto ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
Experimental Studies ◽  
Body Part ◽  
Body Ownership ◽  
Body Parts ◽  
Unique Role ◽  
Affective Touch ◽  
Lesion Symptom Mapping ◽  
The Right ◽  
Right Hemisphere Stroke

AbstractRight hemisphere stroke can impair the ability to recognise one’s contralesional body parts as belonging to one’s self. The study of this so-called ‘disturbed sense of limb ownership’ (DSO) can provide unique insights into the neurocognitive mechanisms of body ownership. Here, we address a hypothesis built upon experimental studies on body ownership in healthy volunteers. These studies have shown that affective (pleasant) touch, an interoceptive modality associated with unmyelinated, slow-conducting C tactile afferents, has a unique role in the sense of body ownership. Here we systematically investigated whether affective touch stimulation could increase body ownership in patients with DSO following right hemisphere stroke. An initial feasibility study in 16 adult, acute stroke patients enabled us to optimise and calibrate an affective touch protocol to be administered by the bedside. The main experiment, conducted with a different sample of 26 right hemisphere patients, assessed changes in limb ownership elicited following self-(patient) versus other-(experimenter) generated tactile stimulation, using a velocity known to optimally activate C-tactile fibres (i.e. 3cm/s), and a second velocity that is suboptimal for C-tactile activation (i.e. 18cm/s). We further examined the specificity and mechanism of observed changes in limb ownership in secondary analyses looking at (1) the influence of perceived intensity and pleasantness of touch, (2) touch laterality, and (3) level of DSO on ownership change, as well as (4) changes in unilateral neglect arising from touch. Findings indicated a significant increase in limb ownership following experimenter-administered, CT-optimal touch. Voxel-based Lesion-Symptom Mapping (VLSM) identified damage to the right insula and, more substantially, the right corpus callosum, associated with a failure to increase body ownership following experimenter-administered, affective touch. Our findings suggest that affective touch can increase the sense of body-part ownership following right hemisphere stroke, potentially due to its unique role in the multisensory integration processes that underlie the sense of body ownership.

scholarly journals Welcoming back my arm: affective touch increases body ownership following right-hemisphere stroke

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Paul M Jenkinson ◽  
Cristina Papadaki ◽  
Sahba Besharati ◽  
Valentina Moro ◽  
Valeria Gobbetto ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
Experimental Studies ◽  
Body Part ◽  
Body Ownership ◽  
Body Parts ◽  
Unique Role ◽  
Affective Touch ◽  
Lesion Symptom Mapping ◽  
The Right ◽  
Right Hemisphere Stroke

Abstract Right-hemisphere stroke can impair the ability to recognize one’s contralesional body parts as belonging to one’s self. The study of this so-called ‘disturbed sense of limb ownership’ can provide unique insights into the neurocognitive mechanisms of body ownership. In this study, we address a hypothesis built upon experimental studies on body ownership in healthy volunteers. These studies have shown that affective (pleasant) touch, an interoceptive modality associated with unmyelinated, slow-conducting C-tactile afferents, has a unique role in the sense of body ownership. In this study, we systematically investigated whether affective touch stimulation could increase body ownership in patients with a disturbed sense of limb ownership following right-hemisphere stroke. An initial feasibility study in 16 adult patients with acute stroke enabled us to optimize and calibrate an affective touch protocol to be administered by the bedside. The main experiment, conducted with a different sample of 26 right hemisphere patients, assessed changes in limb ownership elicited following self- (patient) versus other- (experimenter) generated tactile stimulation, using a velocity known to optimally activate C-tactile fibres (i.e. 3 cm/s), and a second velocity that is suboptimal for C-tactile activation (i.e. 18 cm/s). We further examined the specificity and mechanism of observed changes in limb ownership in secondary analyses looking at (i) the influence of perceived intensity and pleasantness of touch, (ii) touch laterality and (iii) level of disturbed sense of limb ownership on ownership change and (iv) changes in unilateral neglect arising from touch. Findings indicated a significant increase in limb ownership following experimenter-administered, C-tactile-optimal touch. Voxel-based lesion-symptom mapping identified damage to the right insula and, more substantially, the right corpus callosum, associated with a failure to increase body ownership following experimenter-administered, affective touch. Our findings suggest that affective touch can increase the sense of body-part ownership following right-hemisphere stroke, potentially due to its unique role in the multisensory integration processes that underlie the sense of body ownership.

scholarly journals The contribution of stimulating multiple body parts simultaneously to the illusion of owning an entire artificial body

2020 ◽  
Author(s):  
Sophie H. O’Kane ◽  
H. Henrik Ehrsson
Keyword(s):  
Onset Time ◽  
Body Part ◽  
Whole Body ◽  
Multisensory Perception ◽  
Entire Body ◽  
Body Ownership ◽  
Body Parts ◽  
The Right ◽  
Three Body ◽  
Full Body

AbstractThe full-body ownership illusion exploits multisensory perception to induce a feeling of ownership for an entire artificial body. Whilst previous research has shown that the synchronous visuotactile stimulation of a single body part is sufficient for illusory ownership over the whole body, the effect of combining multisensory stimulation across multiple body parts remains unknown. Therefore, 48 healthy adults participated in conditions of a full-body ownership illusion involving synchronous or asynchronous visuotactile stimulation to one, two or three body parts simultaneously (2 x 3 design). We developed a novel questionnaire to isolate the sense of ownership of five specific body parts (left leg, right leg, left arm, right arm, and trunk) from the full-body ownership experience and sought not only to test for greater (part and whole) body ownership in synchronous versus asynchronous stimulation, but also, potentially varying degrees of illusion intensity related to the number of body parts stimulated. As expected, illusory full-body ownership and all five body-part ownership ratings were significantly higher following synchronous stimulation (all p values ≤.01). Since non-stimulated body parts also received significantly higher ownership ratings following synchronous stimulation, the results are consistent with an illusion engaging the entire body. We further noted that ownership ratings for the right body parts (often stimulated) were significantly higher than ownership ratings for the left body parts (never stimulated). Regarding explicit feelings of full-body ownership, subjective ratings were not significantly enhanced by increasing the number of synchronously stimulated body parts (synchronicity x number stimulated interaction; p.099). Instead, median ratings indicated a moderate affirmation (+1) of full-body illusory sensation for all three synchronous conditions; a finding mirrored by full-body illusion onset time. The results support the notion that feelings of full-body ownership are mediated by a generalisation from stimulated part(s)-to-whole, supported by processes related to multisensory body perception.

Adult-to-Adult Living-Donor Liver Transplantation

Swiss Surgery ◽  
2003 ◽  
Vol 9 (5) ◽  
pp. 227-236 ◽  
Author(s):  
Majno ◽  
Mentha ◽  
Berney ◽  
Bühler ◽  
Giostra ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Therapeutic Option ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Multidisciplinary Program ◽  
First Case ◽  
Living Donor Transplantation ◽  
The Right

Living donor liver transplantation is a relatively new procedure in which the right side of the liver is harvested in a healthy donor and transplanted into a recipient. After the first case in 1994, over 3000 cases have been done worldwide. This review summarizes the reasons why the procedure is needed, describes its main technical aspects, highlights the boundaries in which it can be done safely, summarizes the current experience worldwide and describes the main points of the program in our unit. We argue that living-donor transplantation is a viable alternative to a long time on the waiting list for several patients, and it can be performed safely and successfully provided that all precautions are undertaken to minimize the risks in the donor and to increase the chances of a good outcome in the recipients. If these prerequisites are met, and within the framework of a structured multidisciplinary program, we believe that living-donor liver transplantation should be funded by health insurances as a recognized therapeutic option.

Our Bodies, Whose Property?

2013 ◽  
Author(s):  
Anne Phillips
Keyword(s):  
Labor Markets ◽  
Personal Autonomy ◽  
The Body ◽  
Body Parts ◽  
Complex Issue ◽  
Human Organs ◽  
Property Owners ◽  
The Common ◽  
The Difference ◽  
The Right

No one wants to be treated like an object, regarded as an item of property, or put up for sale. Yet many people frame personal autonomy in terms of self-ownership, representing themselves as property owners with the right to do as they wish with their bodies. Others do not use the language of property, but are similarly insistent on the rights of free individuals to decide for themselves whether to engage in commercial transactions for sex, reproduction, or organ sales. Drawing on analyses of rape, surrogacy, and markets in human organs, this book challenges notions of freedom based on ownership of our bodies and argues against the normalization of markets in bodily services and parts. The book explores the risks associated with metaphors of property and the reasons why the commodification of the body remains problematic. The book asks what is wrong with thinking of oneself as the owner of one's body? What is wrong with making our bodies available for rent or sale? What, if anything, is the difference between markets in sex, reproduction, or human body parts, and the other markets we commonly applaud? The book contends that body markets occupy the outer edges of a continuum that is, in some way, a feature of all labor markets. But it also emphasizes that we all have bodies, and considers the implications of this otherwise banal fact for equality. Bodies remind us of shared vulnerability, alerting us to the common experience of living as embodied beings in the same world. Examining the complex issue of body exceptionalism, the book demonstrates that treating the body as property makes human equality harder to comprehend.

Some key body parts and polysemy

2017 ◽  
Author(s):  
Carol Priestley
Keyword(s):  
Human Life ◽  
Body Part ◽  
Cultural Bias ◽  
Body Parts ◽  
Visible Body

This chapter discusses body part nouns, a part of language that is central to human life, and the polysemy that arises in connection with them. Examples from everyday speech and narrative in various contexts are examined in a Papuan language called Koromu and semantic characteristics of body part nouns in other studies are also considered. Semantic templates are developed for nouns that represent highly visible body parts: for example, wapi ‘hands/arms’, ehi ‘feet/legs’, and their related parts. Culture-specific explications are expressed in a natural metalanguage that can be translated into Koromu to avoid the cultural bias inherent in using other languages and to reveal both distinctive semantic components and similarities to cross-linguistic examples.

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