The effect of change in the rhythm of food intake and sleeping time during ramadan on the diurnal variation of fibrinolytic activity

1991 ◽  
Vol 5 (3) ◽  
pp. 177-180 ◽  
Author(s):  
S.M. Bakir ◽  
M.M.T. Kordy ◽  
A.M.A. Gader
Keyword(s):  
Food Intake ◽  
Diurnal Variation ◽  
Fibrinolytic Activity ◽  
Sleeping Time

Fibrinolysis and Alimentary Lipaemia in Whites and Bantus; Their Relationship and Response to Intravenous Heparin

1964 ◽  
Vol 11 (01) ◽  
pp. 108-118 ◽  
Author(s):  
H Lackner ◽  
R Sougin-Mibashan
Keyword(s):  
Diurnal Variation ◽  
Fibrinolytic Activity ◽  
Butter Fat ◽  
Intravenous Heparin ◽  
The Difference

Summary and Conclusion1. Diurnal variation in fibrinolysis is marked in the Whites and almost absent in the Bantu. >2. The difference in fibrinolytic activity beween White and Bantu has been confirmed, but was found to decrease over the course of the morning due to diurnal variation in the White subjects.3. The ingestion of butter fat does not inhibit fibrinolysis to any appreciable extent in either White or Bantu.4. The accelerating effect of heparin on fibrinolysis was found to be present in lipaemic plasma, but appears to be distinct from the fat-clearing effect.

Diurnal Variations in Olfactory Sensitivity and the Relationship to Food Intake

1994 ◽  
Vol 78 (1) ◽  
pp. 215-226 ◽  
Author(s):  
Harry S. Koelega
Keyword(s):  
Food Intake ◽  
Diurnal Variation ◽  
Diurnal Variations ◽  
Consistent Pattern ◽  
Olfactory Sensitivity ◽  
Group Data ◽  
The Future ◽  
The Relationship

At least a dozen studies have investigated the effects of food intake on olfactory sensitivity. Most studies reported the existence of food-related changes in sensitivity but the findings are highly discrepant. In the present study, earlier studies are reviewed, their shortcomings discussed, and the results of an experiment are reported. Using an air-dilution olfactometer, sensitivity to the odor of acetophenone was assessed throughout the day in seven subjects on four consecutive days, both with and without lunch. In the group data no consistent pattern of changes in sensitivity related to food intake was found, although some individual subjects showed a diurnal variation. Some suggestions are made enhancing the possibility that in the future a relationship between food intake and olfactory sensitivity may be observed.

PLASMA INSULIN AND GROWTH HORMONE IN DAIRY COWS; DIURNAL VARIATION AND RELATION TO FOOD INTAKE AND PLASMA SUGAR AND ACETOACETATE LEVELS

1973 ◽  
Vol 73 (2) ◽  
pp. 289-303 ◽  
Author(s):  
Knut Hove ◽  
Anne Kristine Blom
Keyword(s):  
Growth Hormone ◽  
Food Intake ◽  
Diurnal Variation ◽  
Dairy Cows ◽  
Plasma Levels ◽  
Plasma Insulin ◽  
Diurnal Variations ◽  
Plasma Growth Hormone ◽  
The Mean ◽  
Different Levels

ABSTRACT Marked diurnal variations were found in plasma growth hormone (GH), insulin, acetoacetate (AcAc) and sugar in two herds (U and A) of dairy cows kept at two different levels of feeding. Seven animals from each herd were tested. The main diurnal variations were related to food intake, a significant increase in plasma insulin, and a significant decrease in plasma sugar being found. The acetoacetate level rose significantly during feeding in herd U (moderately underfed), while no significant increase was found in herd A (adequately fed). Plasma growth hormone was found to decrease (P < 0.01) only during feeding in herd U, while no change in the GH level could be detected in herd A. The mean level of GH in herd U was found to be twice the value found in herd A. There were no significant differences between the herds in plasma insulin and sugar. Significant differences in plasma levels of GH, insulin and sugar were found between animals when analysed within the herds. Variations in the levels of insulin and acetoacetate were very small during the night. This is contrary to GH, which shows the least variation during food intake. The correlation coefficient between the plasma components was low, although in many cases significant.

scholarly journals Diurnal Variation in Rat Liver Thyroid Hormone Receptor (TR)-α Messenger Ribonucleic Acid (mRNA) Is Dependent on the Biological Clock in the Suprachiasmatic Nucleus, whereas Diurnal Variation of TRβ1 mRNA Is Modified by Food Intake

Endocrinology ◽  
2004 ◽  
Vol 145 (3) ◽  
pp. 1284-1289 ◽  
Author(s):  
B. Zandieh Doulabi ◽  
M. Platvoet-Ter Schiphorst ◽  
A. Kalsbeek ◽  
E. Fliers ◽  
O. Bakker ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Food Intake ◽  
Diurnal Variation ◽  
Mrna Expression ◽  
Suprachiasmatic Nucleus ◽  
Rat Liver ◽  
Thyroid Hormone Receptor ◽  
Biological Clock ◽  
Free Access ◽  
Diurnal Changes

Abstract Previous studies have shown a diurnal variation of certain isoforms of thyroid hormone receptors (TR) in rat liver. The genesis of these diurnal changes is still unknown. To clarify whether the biological clock, located in the hypothalamic suprachiasmatic nucleus (SCN), is involved, we made selective SCN lesions. Rats with an SCN lesion lost their circadian rhythm of plasma corticosterone and TSH when compared with intact animals. TRα1 and TRα2 mRNA expression of control rats was higher in the light period than in the dark period; changes that were abolished in the rats with SCN lesions. In contrast, liver TRβ1 mRNA of intact rats showed a diurnal variation that failed to reach statistical significance. To evaluate whether these effects could be explained indirectly by the disappearance of rhythmic feeding behavior in rats with SCN lesions, we performed a second experiment in which otherwise intact animals were subjected to a regular feeding (RF) schedule, with one meal every 4 h. When compared with rats with free access to food, RF only affected TRβ1 mRNA expression and had no effect on the diurnal changes in TRα1 and TRα2. We conclude that liver TRβ1 expression is most clearly affected by food intake. Diurnal changes in liver TRα1 and TRα2 are controlled by the biological clock in the SCN but not via changes in the daily rhythm of food intake. The findings may have physiological relevance for diurnal variation of T3-dependent gene expression, which is supported by a diurnal variation in the expression of the 5′-deiodinase gene.

URINARY EXCRETION OF CALCIUM, HYDROXYPROLINE AND 3′,5′-CYCLIC ADENOSINE MONOPHOSPHATE IN PRIMARY HYPERPARATHYROIDISM

1979 ◽  
Vol 92 (1) ◽  
pp. 138-147 ◽  
Author(s):  
Johan Halse ◽  
Jan O. Gordeladze
Keyword(s):  
Food Intake ◽  
Primary Hyperparathyroidism ◽  
Urinary Excretion ◽  
Diurnal Variation ◽  
Cyclic Adenosine Monophosphate ◽  
Adenosine Monophosphate ◽  
Parathyroid Surgery ◽  
Creatinine Ratio ◽  
Parathyroid Function ◽  
The Individual

ABSTRACT Urinary excretion of calcium (Ca), hydroxyproline (Hyp) and 3′,5′-cyclic adenosine monophosphate (cAMP) was measured during fasting, and in the afternoon, over a 3 day period. Twelve hyperparathyroid patients, of whom 6 were re-studied after successful parathyroid surgery, and 10 control subjects participated, and were maintained on a collagen free diet for the duration of the study. Expressed as creatinine ratio values, Hyp was significantly higher in the morning than during the afternoon, whereas the Ca excretion pattern showed low morning and high afternoon values for all groups. cAMP excretion did not change during the two sampling periods. Large day to day variations for each parameter were observed in the individual patient. The value of cAMP measurements in the diagnosis of primary hyperparathyroidism was confirmed. The results may imply that a diurnal variation in Hyp excretion exists in primary hyperparathyroidism and that food intake produces a suppression of Hyp excretion, possibly secondary to suppression of parathyroid function or, in our view, to increased calcitonin excretion.

Effects of food intake and cholecystokinin on plasma trypsinogen levels in dogs

1984 ◽  
Vol 246 (5) ◽  
pp. G543-G549 ◽  
Author(s):  
R. D. Reidelberger ◽  
M. O'Rourke ◽  
P. R. Durie ◽  
M. C. Geokas ◽  
C. Largman
Keyword(s):  
Food Intake ◽  
Diurnal Variation ◽  
Plasma Levels ◽  
Exocrine Secretion ◽  
Low Doses ◽  
Feeding Period ◽  
Cholecystokinin Octapeptide ◽  
Before And After ◽  
Cationic Trypsin ◽  
Normal Feeding

Concentrations of plasma immunoreactive anionic and cationic trypsin(ogen) were monitored in unanesthetized dogs to investigate diurnal variation, response to food intake, and effects of cholecystokinin octapeptide (CCK-8) plus secretin administration. Identical meals were consumed at the beginning and end of a 24-h period. Plasma levels of both trypsin(ogen)s increased significantly within 30 min of feeding. Second-meal responses were much larger than those following the first meal. Plasma cationic trypsin(ogen) was also elevated during the normal feeding period when food was withheld and dogs in adjacent cages were fed. Small, irregular variations in plasma trypsin(ogen)s occurred during the interdigestive period when blood was sampled every 2 h. CCK-8 plus secretin, in doses shown previously to stimulate exocrine secretion of enzymes submaximally, increased plasma levels of both trypsin(ogen)s dose dependently. Most (greater than 80%) of the immunoreactive cationic trypsin(ogen) in plasma before and after feeding and following CCK-8 was in proenzyme form. We conclude that plasma levels of pancreatic trypsinogens are increased by food intake and low doses of CCK-8. Furthermore, cephalic mechanisms appear to play an important role in mediating the response to food intake.

Diurnal Variation of the Fibrinolytic System

1988 ◽  
Vol 59 (03) ◽  
pp. 495-499 ◽  
Author(s):  
V Grimaudo ◽  
J Hauert ◽  
F Bachmahh ◽  
E K O Kruithof
Keyword(s):  
Diurnal Variation ◽  
Plasminogen Activator ◽  
Fibrinolytic Activity ◽  
Significant Proportion ◽  
Plasminogen Activator Inhibitor ◽  
Fibrinolytic System ◽  
Tissue Type ◽  
Clot Lysis ◽  
Euglobulin Clot Lysis Time ◽  
Pai 1

AbstractTo elucidate which component(s) of thei fibrinolytic system is (are) responsible for the diurnal variation of fibrinolytic activity we have studied several parameters of this system in 8 healthy male volunteers during a period of. 24 h. Blood was collected at 8 a. m., 10 a. m., 12 a. m., 4 p.m., 8 p.m. and 8 a. m. next morning. The following tests were performed: euglobulin clot lysis time (ECLT), fibrinolytic activity of euglobulins on fibrin plates in the presence and absence of blocking antibodies to tissue-type plasminogen activator (t-PA) and/or urokinase (u-PA), overall plasminogen activator inhibitor (PAI) activity, antigen levels of t-PA, u-PA and PAI-I and zymography of the euglobulin fraction after SDS-PAGE. From 8-10 a. m. to 4-8 p. m., total fibrinolytic activity increased by 1l3% (p <0.01) or 71%h (p <0.01) when measured by ECIX or by fibrin plate assay, respectively. The immunoquenching experiments showed that this increase was entirely due to t-PA related activity whereas u-PA activity and t-PA/u-PA independent activity remained constant during the day. Average antigen levels of u-PA and t-PA in the afternoon were 6% and 25% lower than those measured in the morning. During this period, overall PAI activity and PAI-1 antigen decreased by 3l% (p <0.01) and 52% (p <0.01) respectively. Electrophoretic-zymographic analysis of_ the euglobulins revealed that throughout the day the majority of t-PA was present in the form of the 110 kDa t-PA/PAI-I complex. The intensity of this cornplex was lowest in the afternoon. Free t-PA was almost undetectable in morning samples, but constituted a significant proportion of total t-PA in the afternoon. The diurnal increase of fibrinolytic activity, therefore, is not due to an augmentation of antigen levels of t-PA and/or u-PA but to a decline of those of PAI-1.

scholarly journals Effects of simmondsin on food intake, growth, and metabolic variables in lean (+/?) and obese (fa/fa) Zucker rats

1999 ◽  
Vol 81 (2) ◽  
pp. 159-167 ◽  
Author(s):  
G. Flo ◽  
S. Vermaut ◽  
V. M. Darras ◽  
M. Van Boven ◽  
E. Decuypere ◽  
...  
Keyword(s):  
Food Intake ◽  
Diurnal Variation ◽  
Total Cholesterol ◽  
Heat Production ◽  
Hdl Cholesterol ◽  
Zucker Rats ◽  
Cholesterol Levels ◽  
Obese Rats ◽  
Obese Zucker Rats ◽  
Production Pattern

Incorporation of 2·5 g/kg of the anorexigen, simmondsin, in the diet resulted in food intake reduction in both lean and obese Zucker rats; however, the obese rats were much more sensitive to the food intake-reducing activity of simmondsin. In both obese and lean simmondsin-treated Zucker rats, growth was slower than in control rats, but was the same as that in pair-fed animals. The 24 h heat production pattern showed a smaller diurnal variation and a lower mean in obese rats than in lean rats. Food intake reduction, as a result of either simmondsin treatment or pair feeding, caused a decrease in mean heat production. Simmondsin treatment, but not pair feeding, caused a decrease in the diurnal variation of heat production. Plasma total cholesterol levels were increased in both simmondsin-treated and pair-fed obese and lean Zucker rats compared with control animals; this increase was mainly due to an increase in HDL-cholesterol levels. Blood leptin levels in both obese and lean rats decreased with decreased food intake and decreased fat deposition, but in obese rats, simmondsin treatment resulted in an additional decrease in leptin levels. It is concluded that the food intake-reducing effect of simmondsin is more pronounced in obese Zucker rats than in their lean littermates, and except for the simmondsin-specific effects on leptin and total cholesterol values in obese littermates, the effects of simmondsin are related to food intake restriction in obese and lean Zucker rats.

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