Antimicrobial Resistance Progression in the United Kingdom: A Temporal Comparison of Clostridioides difficile Antimicrobial Susceptibilities

Anaerobe ◽  
2021 ◽  
pp. 102385
Author(s):  
Vernon Jon J ◽  
Wilcox Mark H ◽  
Freeman Jane
Keyword(s):  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Temporal Comparison ◽  
Clostridioides Difficile ◽  
The United Kingdom ◽  
Antimicrobial Susceptibilities

scholarly journals Changes in the Framing of Antimicrobial Resistance in Print Media in Australia and the United Kingdom (2011–2020): A Comparative Qualitative Content and Trends Analysis

Antibiotics ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1432
Author(s):  
Chris Degeling ◽  
Victoria Brookes ◽  
Tarant Hill ◽  
Julie Hall ◽  
Anastacia Rowles ◽  
...  
Keyword(s):  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Scientific Discovery ◽  
Public Awareness ◽  
Media Framing ◽  
Public Health Response ◽  
Large Hospital ◽  
The United Kingdom ◽  
Health Response ◽  
Community Outbreaks

Educating the public about antimicrobial resistance (AMR) is considered a key part of an optimal public health response. In both media depictions and policy discourses around health risks, how a problem is framed underpins public awareness and understanding, while also guiding opinions on what actions can and should be taken. Using a mixed methods approach we analyse newspaper content in Australia and the United Kingdom (UK) from 2011 to 2020 to track how causes, consequences and solutions to AMR are represented in countries with different policy approaches. Analyses demonstrate greater variability in the frames used in UK newspapers reflecting large hospital and community outbreaks and a sustained period of policy reform mid-decade. Newspapers in Australia focus more on AMR causes and consequences, highlighting the importance of scientific discovery, whereas UK coverage has greater discussion of the social and economic drivers of AMR and their associated solutions. Variations in the trends of different frames around AMR in UK newspapers indicate greater levels of public deliberation and debate around immediate and actionable solutions; whereas AMR has not had the same health and political impacts in Australia resulting in a media framing that potentially encourages greater public complacency about the issue.

scholarly journals Antimicrobial resistance risk factors and characterisation of faecal E. coli isolated from healthy Labrador retrievers in the United Kingdom

2015 ◽  
Vol 119 (1-2) ◽  
pp. 31-40 ◽  
Author(s):  
Vanessa M. Schmidt ◽  
Gina L. Pinchbeck ◽  
Tim Nuttall ◽  
Neil McEwan ◽  
Susan Dawson ◽  
...  
Keyword(s):  
Risk Factors ◽  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Resistance Risk ◽  
E Coli ◽  
The United Kingdom ◽  
Labrador Retrievers

scholarly journals A General Public Study on Preferences and Welfare Impacts of Antimicrobial Resistance in the United Kingdom

2021 ◽  
Author(s):  
Maria Veronica Dorgali ◽  
Alberto Longo ◽  
Caroline Vass ◽  
Gemma Shields ◽  
Roger Harrison ◽  
...  
Keyword(s):  
United Kingdom ◽  
Antimicrobial Resistance ◽  
General Public ◽  
Welfare Impacts ◽  
The United Kingdom

scholarly journals First Neisseria gonorrhoeae strain with resistance to cefixime causing gonorrhoea treatment failure in Austria, 2011

2011 ◽  
Vol 16 (43) ◽  
Author(s):  
M Unemo ◽  
D Golparian ◽  
A Stary ◽  
A Eigentler
Keyword(s):  
Public Health ◽  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Neisseria Gonorrhoeae ◽  
Treatment Failure ◽  
Effective Treatment ◽  
Therapeutic Failure ◽  
Health Control ◽  
Gonorrhoeae Strain ◽  
The United Kingdom

We describe the first cefixime-resistant Neisseria gonorrhoeae strain in Austria that caused treatment failure. It follows the first five cases in Europe of cefixime treatment failure, reported in Norway in 2010 and the United Kingdom in 2011. Effective treatment of gonorrhoea is crucial for public health control and, at present, requires substantially enhanced awareness, more frequent test-of-cure, interaction with experts after therapeutic failure, tracing and therapy of contacts, and surveillance of gonococcal antimicrobial resistance and treatment failures worldwide.

scholarly journals Comparison of genotypes, antimicrobial resistance and virulence profiles of oral and non oral Enterococcus faecalis from Brazil, Japan and the United Kingdom

2019 ◽  
Vol 84 ◽  
pp. 49-54
Author(s):  
Renata Ximenes Lins ◽  
Raphael Hirata ◽  
Melanie Wilson ◽  
Michael A. O Lewis ◽  
Rivail Antonio Sergio Fidel ◽  
...  
Keyword(s):  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Enterococcus Faecalis ◽  
The United Kingdom

scholarly journals Antibiotic and Metal Resistance in Escherichia coli Isolated from Pig Slaughterhouses in the United Kingdom

Antibiotics ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 746
Author(s):  
Hongyan Yang ◽  
Shao-Hung Wei ◽  
Jon L. Hobman ◽  
Christine E. R. Dodd
Keyword(s):  
Escherichia Coli ◽  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Metal Resistance ◽  
E Coli ◽  
The United Kingdom ◽  
Important Concern ◽  
Pathogenic Escherichia Coli ◽  
Amoxicillin Clavulanic Acid ◽  
Few Data

Antimicrobial resistance is currently an important concern, but there are few data on the co-presence of metal and antibiotic resistance in potentially pathogenic Escherichia coli entering the food chain from pork, which may threaten human health. We have examined the phenotypic and genotypic resistances to 18 antibiotics and 3 metals (mercury, silver, and copper) of E. coli from pig slaughterhouses in the United Kingdom. The results showed resistances to oxytetracycline, streptomycin, sulphonamide, ampicillin, chloramphenicol, trimethoprim–sulfamethoxazole, ceftiofur, amoxicillin–clavulanic acid, aztreonam, and nitrofurantoin. The top three resistances were oxytetracycline (64%), streptomycin (28%), and sulphonamide (16%). Two strains were resistant to six kinds of antibiotics. Three carried the blaTEM gene. Fifteen strains (18.75%) were resistant to 25 µg/mL mercury and five (6.25%) of these to 50 µg/mL; merA and merC genes were detected in 14 strains. Thirty-five strains (43.75%) showed resistance to silver, with 19 possessing silA, silB, and silE genes. Fifty-five strains (68.75%) were resistant to 8 mM copper or above. Seven contained the pcoE gene. Some strains were multi-resistant to antibiotics, silver, and copper. The results in this study, based on strains isolated between 2007 and 2010, will aid understanding about the effects of strategies to reduce resistance and mechanisms of antimicrobial resistance (AMR).

scholarly journals Does gonorrhoea screening intensity play a role in the early selection of antimicrobial resistance in men who have sex with men (MSM)? A comparative study of Belgium and the United Kingdom

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 569 ◽  
Author(s):  
Chris R. Kenyon ◽  
Irith De Baetselier ◽  
Tania Crucitti
Keyword(s):  
United Kingdom ◽  
Antimicrobial Resistance ◽  
The United States ◽  
National Surveillance ◽  
Surveillance Programme ◽  
The Past ◽  
The United Kingdom ◽  
Sex With Men ◽  
The Uk ◽  
Selection Of

Background: It is unclear why antimicrobial resistance in Neisseria gonorrhoeae in the United Kingdom (UK) and the United States has tended to first appear in men who have sex with men (MSM). We hypothesize that increased exposure to antimicrobials from intensive STI screening programmes plays a role. Methods: We assess if there is a difference in the distribution of azithromycin, cefixime and ceftriaxone minimum inhibitory concentrations (MICs) between MSM and women in the United Kingdom (UK) where 70% of MSM report STI screening in the past year vs. Belgium where 9% report STI screening in the past year. Our hypothesis is that MICs of the MSM should be higher than those of the women in the UK but not Belgium. Data for the MICs were taken from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in the UK in 2010/2011 and 2014 and a similar national surveillance programme in Belgium in 2013/2014 (the first most complete available data). We used the Mann–Whitney test to compare the MIC distributions between MSM and women within each country Results: In the UK the MICs for all three antimicrobials were significantly higher in MSM than women at both time points (P all <0.0005). In Belgium only the MIC distribution for azithromycin was higher in MSM (P<0.0005). Conclusion: The findings for cefixime and ceftriaxone, but not azithromycin are compatible with our hypothesis that screening-intensity could contribute to the emergence of AMR. Numerous other interpretations of our results are discussed.

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